Search results for: Genetic code vector space

Authors: Olumuyiwa A. Lasode, Tajudeen O. Popoola, B. V. S. S. S. Prasad

Abstract:

Fluid flow in cylinders of elliptic cross-section was investigated. Fluid used is Liquefied petroleum gas (LPG). LPG found in Nigeria contains majorly butane with percentages of propane. Commercial available code FLUENT which uses finite volume method was used to solve fluid flow governing equations. There has been little attention paid to fluid flow in cylindrical elliptic pipes. The present work aims to predict the LPG gas flow in cylindrical pipes of elliptic cross-section. Results of flow parameters of velocity and pressure distributions are presented. Results show that the pressure drop in elliptic pipes is higher than circular pipe of the same cross-sectional area. This is an important result as the pressure drop is related to the pump power needed to drive the flow. Results show that the velocity increases towards centre of the pipe as the flow moves downstream, and also increases towards the outlet of the pipe.

Keywords: Elliptic Pipes, Liquefied Petroleum Gas, Numerical Study, Pressure Drop.

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Authors: Dong-Chul Lee, Byung-Kwan Oh, Se-Woon Choi, Hyo-Sun Park

Abstract:

The unanticipated brittle fracture of connection of the steel moment resisting frame (SMRF) occurred in 1994 the Northridge earthquake. Since then, the researches for the vulnerability of connection of the existing SMRF and for rehabilitation of those buildings were conducted. This paper suggests performance-based optimal seismic retrofit technique using connection upgrade. For optimal design, a multi-objective genetic algorithm(NSGA-II) is used. One of the two objective functions is to minimize initial cost and another objective function is to minimize lifetime seismic damages cost. The optimal algorithm proposed in this paper is performed satisfying specified performance objective based on FEMA 356. The nonlinear static analysis is performed for structural seismic performance evaluation. A numerical example of SAC benchmark SMRF is provided using the performance-based optimal seismic retrofit technique proposed in this paper

Keywords: connection upgrade, performace-based seismicdesign, seismic retrofit, multi-objective optimization

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Authors: Moghiman Mohammad, Amiri Maryam, Amiri Amirhosein

Abstract:

The present paper develops and validates a numerical procedure for the calculation of turbulent combustive flow in converging and diverging ducts and throuh simulation of the heat transfer processes, the amount of production and spread of Nox pollutant has been measured. A marching integration solution procedure employing the TDMA is used to solve the discretized equations. The turbulence model is the Prandtl Mixing Length method. Modeling the combustion process is done by the use of Arrhenius and Eddy Dissipation method. Thermal mechanism has been utilized for modeling the process of forming the nitrogen oxides. Finite difference method and Genmix numerical code are used for numerical solution of equations. Our results indicate the important influence of the limiting diverging angle of diffuser on the coefficient of recovering of pressure. Moreover, due to the intense dependence of Nox pollutant to the maximum temperature in the domain with this feature, the Nox pollutant amount is also in maximum level.

Keywords: Converging and Diverging Duct, Combustion, Diffuser, Diverging Angle, Nox

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Authors: H. Shayeghi, M. Mahdavi, A. Kazemi

Abstract:

Transmission network expansion planning (TNEP) is a basic part of power system planning that determines where, when and how many new transmission lines should be added to the network. Up till now, various methods have been presented to solve the static transmission network expansion planning (STNEP) problem. But in all of these methods, transmission expansion planning considering network adequacy restriction has not been investigated. Thus, in this paper, STNEP problem is being studied considering network adequacy restriction using discrete particle swarm optimization (DPSO) algorithm. The goal of this paper is obtaining a configuration for network expansion with lowest expansion cost and a specific adequacy. The proposed idea has been tested on the Garvers network and compared with the decimal codification genetic algorithm (DCGA). The results show that the network will possess maximum efficiency economically. Also, it is shown that precision and convergence speed of the proposed DPSO based method for the solution of the STNEP problem is more than DCGA approach.

Keywords: DPSO algorithm, Adequacy restriction, STNEP.

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Authors: Ahmed H. Amer, A. Amar, Sh. Hamada, I. I. Bondouk, F. A. El-Hussiny

Abstract:

Elastic scattering of α-particles from 9Be and 11B nuclei at different alpha energies have been analyzed. Optical model parameters (OMPs) of α-particles elastic scattering by these nuclei at different energies have been obtained. In the present calculations, the real part of the optical potential are derived by folding of nucleonnucleon (NN) interaction into nuclear matter density distribution of the projectile and target nuclei using computer code FRESCO. A density-dependent version of the M3Y interaction (CDM3Y6), which is based on the G-matrix elements of the Paris NN potential, has been used. Volumetric integrals of the real and imaginary potential depth (JR, JW) have been calculated and found to be energy dependent. Good agreement between the experimental data and the theoretical predictions in the whole angular range. In double folding (DF) calculations, the obtained normalization coefficient Nr is in the range 0.70–1.32.

Keywords: Elastic scattering of α-particles, optical model parameters, double folding model, nucleon-nucleon interaction.

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Authors: Neville Fernandes, Satish Shenoy B., Raghuvir Pai B., Rammohan S. Pai B, Shrikanth Rao.D

Abstract:

This research details a Computational Fluid Dynamics (CFD) approach to model fluid flow in a journal bearing with 8 equispaced semi-circular axial grooves. Water is used as the lubricant and is fed from one end of the bearing to the other, under pressure. The geometry of the bearing is modeled using a commercially available modeling software GAMBIT and the flow analysis is performed using a dedicated CFD analysis software FLUENT. The pressure distribution in the bearing clearance is obtained from FLUENT for various whirl ratios and is used to calculate the hydrodynamic force components in the radial and tangential direction of the bearing. These values along with the various whirl speeds can be used to do a regression analysis to determine the stiffness and damping coefficients. The values obtained are then compared with the stiffness and damping coefficients of a 3 Axial groove water lubricated journal bearing and those obtained from a FORTRAN code for a similar bearing.

Keywords: CFD, multiple axial groove, Water lubricated, Stiffness and Damping Coefficients.

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Authors: Feifei Lee, Qiu Chen, Koji Kotani, Tadahiro Ohmi

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In this paper, we propose an improved fast search algorithm using combined histogram features and temporal division method for short MPEG video clips from large video database. There are two types of histogram features used to generate more robust features. The first one is based on the adjacent pixel intensity difference quantization (APIDQ) algorithm, which had been reliably applied to human face recognition previously. An APIDQ histogram is utilized as the feature vector of the frame image. Another one is ordinal feature which is robust to color distortion. Combined with active search [4], a temporal pruning algorithm, fast and robust video search can be realized. The proposed search algorithm has been evaluated by 6 hours of video to search for given 200 MPEG video clips which each length is 30 seconds. Experimental results show the proposed algorithm can detect the similar video clip in merely 120ms, and Equal Error Rate (ERR) of 1% is achieved, which is more accurately and robust than conventional fast video search algorithm.

Keywords: Fast search, Adjacent pixel intensity differencequantization (APIDQ), DC image, Histogram feature.

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Authors: Gökhan Silahtaroğlu

Abstract:

Clustering large populations is an important problem when the data contain noise and different shapes. A good clustering algorithm or approach should be efficient enough to detect clusters sensitively. Besides space complexity, time complexity also gains importance as the size grows. Using hierarchies we developed a new algorithm to split attributes according to the values they have and choosing the dimension for splitting so as to divide the database roughly into equal parts as much as possible. At each node we calculate some certain descriptive statistical features of the data which reside and by pruning we generate the natural clusters with a complexity of O(n).

Keywords: Clustering, tree, split, pruning, entropy, gini.

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Authors: Gururaj S Punekar, N K Kishore Senior, H S Y Shastry

Abstract:

Charge Simulation Method (CSM) is one of the very widely used numerical field computation technique in High Voltage (HV) engineering. The high voltage fields of varying non uniformities are encountered in practice. CSM programs being case specific, the simulation accuracies heavily depend on the user (programmers) experience. Here is an effort to understand CSM errors and evolve some guidelines to setup accurate CSM models, relating non uniformities with assignment factors. The results are for the six-point-charge model of sphere-plane gap geometry. Using genetic algorithm (GA) as tool, optimum assignment factors at different non uniformity factors for this model have been evaluated and analyzed. It is shown that the symmetrically placed six-point-charge models can be good enough to set up CSM programs with potential errors less than 0.1% when the field non uniformity factor is greater than 2.64 (field utilization factor less than 52.76%).

Keywords: Assignment factor, Charge Simulation Method, High Voltage, Numerical field computation, Non uniformity factor, Simulation errors.

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Authors: G. Seksenbaeva, K. Atabayev, N. Alpusbaeva, T. Tulebayev, G. Sabdenova

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In article are analyzed value of audiovisual sources which possesses high integrative potential and allows studying movement of information in the history - information movement from generation to the generation, in essence providing continuity of historical development and inheritance of traditions. Information thus fixed in them is considered as a source not only about last condition of society, but also significant for programming of its subsequent activity.

Keywords: Historical source, audiovisual documents, audiovisual source, film documents, photo documents, phonodocuments, cultural heritage, National Archives, material culture, spiritual culture.

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Authors: Sanjay Singh, M Sathish Kumar, H. S Mruthyunjaya

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Multicarrier transmission system such as Orthogonal Frequency Division Multiplexing (OFDM) is a promising technique for high bit rate transmission in wireless communication systems. OFDM is a spectrally efficient modulation technique that can achieve high speed data transmission over multipath fading channels without the need for powerful equalization techniques. A major drawback of OFDM is the high Peak-to-Average Power Ratio (PAPR) of the transmit signal which can significantly impact the performance of the power amplifier. In this paper we have compared the PAPR reduction performance of Golay and Reed-Muller coded OFDM signal. From our simulation it has been found that the PAPR reduction performance of Golay coded OFDM is better than the Reed-Muller coded OFDM signal. Moreover, for the optimum PAPR reduction performance, code configuration for Golay and Reed-Muller codes has been identified.

Keywords: OFDM, PAPR, Perfect Codes, Golay Codes, Reed-Muller Codes

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Authors: Anas M. Fares, A. Touqan

Abstract:

A common approach in resisting lateral forces is the use of reinforced concrete shear walls in buildings. These walls represent the main elements to resist the lateral forces due to their large strength and stiffness. However, such walls may contain many openings due to functional requirements, and this may largely affect the overall lateral stiffness of them. It is thus of prime importance to quantify the effect of openings on the dynamic performance of the shear walls. SAP2000 structural analysis program is used as a main source after verifying the results. This study is made by using linear elastic analysis. The results are compared to ASCE7-16 code empirical equations for estimating the fundamental period of shear wall structures. Finally, statistical regression is used to fit an equation for estimating the increase in the fundamental period of shear-walled regular structures due to windows openings in the walls.

Keywords: Concrete, earthquake-resistant design, finite element, fundamental period, lateral stiffness, linear analysis, modal analysis, rayleigh, SAP2000, shear wall, ASCE7-16.

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Authors: R. Rinkeviciene, B. Kundrotas, S. Lisauskas

Abstract:

In this paper, the authors take a look at advantages of multiphase induction motors comparing them with three phase ones and present the applications where six-phase induction motors are used. They elaborate the mathematical model of six-phase induction motor with two similar stator three phase winding, shifted by 30 degrees in space and three phase winding in rotor, in synchronous reference frame for soft starting and scalar control. The authors simulate and discuss results of speed and torque starting transients.

Keywords: Model, scalar control, six-phase induction motor.

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Authors: Qinyi Mei, Li-Ping Wang

Abstract:

MDS matrices are of great significance in the design of block ciphers and hash functions. In the present paper, we investigate the problem of constructing MDS matrices which are both lightweight and low-latency. We propose a new method of constructing lightweight MDS matrices using circulant matrices which can be implemented efficiently in hardware. Furthermore, we provide circulant MDS matrices with as few bit XOR operations as possible for the classical dimensions 4 × 4, 8 × 8 over the space of linear transformations over finite field F42 . In contrast to previous constructions of MDS matrices, our constructions have achieved fewer XORs.

Keywords: Linear diffusion layer, circulant matrix, lightweight, MDS matrix.

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Authors: J. P. Dubois, O. M. Abdul-Latif

Abstract:

Support Vector Machine (SVM) is a statistical learning tool that was initially developed by Vapnik in 1979 and later developed to a more complex concept of structural risk minimization (SRM). SVM is playing an increasing role in applications to detection problems in various engineering problems, notably in statistical signal processing, pattern recognition, image analysis, and communication systems. In this paper, SVM was applied to the detection of medical ultrasound images in the presence of partially developed speckle noise. The simulation was done for single look and multi-look speckle models to give a complete overlook and insight to the new proposed model of the SVM-based detector. The structure of the SVM was derived and applied to clinical ultrasound images and its performance in terms of the mean square error (MSE) metric was calculated. We showed that the SVM-detected ultrasound images have a very low MSE and are of good quality. The quality of the processed speckled images improved for the multi-look model. Furthermore, the contrast of the SVM detected images was higher than that of the original non-noisy images, indicating that the SVM approach increased the distance between the pixel reflectivity levels (detection hypotheses) in the original images.

Keywords: LS-SVM, medical ultrasound imaging, partially developed speckle, multi-look model.

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Authors: Abdullah A. Al Orainy

Abstract:

Small cell backhaul solutions need to be cost-effective, scalable, and easy to install. This paper presents an overview of small cell backhaul technologies. Wireless solutions including TV white space, satellite, sub-6 GHz radio wave, microwave and mmWave with their backhaul characteristics are discussed. Recent research on issues like beamforming, backhaul architecture, precoding and large antenna arrays, and energy efficiency for dense small cell backhaul with mmWave communications is reviewed. Recent trials of 5G technologies are summarized.

Keywords: Backhaul, Small Cells, Wireless, 5G.

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Authors: M. Seifi, S. Fallah, M. Firoozrai

Abstract:

Matrix metalloproteinase-3 (MMP3) is key member of the MMP family, and is known to be present in coronary atherosclerotic. Several studies have demonstrated that MMP-3 5A/6A polymorphism modify each transcriptional activity in allele specific manner. We hypothesized that this polymorphism may play a role as risk factor for development of coronary stenosis. The aim of our study was to estimate MMP-3 (5A/6A) gene polymorphism on interindividual variability in risk for coronary stenosis in an Iranian population.DNA was extracted from white blood cells and genotypes were obtained from coronary stenosis cases (n=95) and controls (n=100) by PCR (polymerase chain reaction) and restriction fragment length polymorphism techniques. Significant differences between cases and controls were observed for MMP3 genotype frequencies (X2=199.305, p< 0.001); the 6A allele was less frequently seen in the control group, compared to the disease group (85.79 vs. 78%, 6A/6A+5A/6A vs. 5A/5A, P≤0.001). These data imply the involvement of -1612 5A/6A polymorphism in coronary stenosis, and suggest that probably the 6A/6A MMP-3 genotype is a genetic susceptibility factor for coronary stenosis.

Keywords: Coronary artery stenosis, matrixmetalloproteinase-3, polymorphism, polymerase chain reaction.

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Authors: D. SuganyaDevi, G. Padmavathi

Abstract:

Reliable secure multicast communication in mobile adhoc networks is challenging due to its inherent characteristics of infrastructure-less architecture with lack of central authority, high packet loss rates and limited resources such as bandwidth, time and power. Many emerging commercial and military applications require secure multicast communication in adhoc environments. Hence key management is the fundamental challenge in achieving reliable secure communication using multicast key distribution for mobile adhoc networks. Thus in designing a reliable multicast key distribution scheme, reliability and congestion control over throughput are essential components. This paper proposes and evaluates the performance of an enhanced optimized multicast cluster tree algorithm with destination sequenced distance vector routing protocol to provide reliable multicast key distribution. Simulation results in NS2 accurately predict the performance of proposed scheme in terms of key delivery ratio and packet loss rate under varying network conditions. This proposed scheme achieves reliability, while exhibiting low packet loss rate with high key delivery ratio compared with the existing scheme.

Keywords: Key Distribution, Mobile Adhoc Network, Multicast and Reliability.

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Authors: Pavan Badami, Vivek Shrivastava, Saravanan V., Nandeesh Hiremath, K. N. Seetharamu

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In the present work flow past circular cylinder and cylinder with rectangular and triangular wake splitter is studied to improve aerodynamic parameters. The Comparison of drag coefficient is tabulated for bare cylinder, cylinder with rectangular and triangular wake splitters. Flow past circular cylinder and cylinder with triangular and rectangular wake splitter is performed at Reynoldsnumber 5, 20, 40, 50,80, 100.An incompressible PISO finite volume code employing a non-staggered grid arrangement is used, a second order upwind scheme is used for convective terms. The time discretization is implicit and a Second order Crank-Nicholson scheme is employed. Length of wake splitter in both configurations is taken to be equal to diameter of cylinder. Wake length is found to be less with rectangular wake splitter when compared to bare cylinder and cylinder with triangular wake splitter. Coefficient of drag is found to be less for triangular wake splitter when compared to bare cylinder & cylinder with rectangular wake splitter.

Keywords: Coefficient of drag and pressure, CFDFLUENT, Triangular and rectangular wake splitter, wake length.

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Authors: Surendran M, Palani G. S, Nagesh R. Iyer

Abstract:

Multi-site damage (MSD) has been a challenge to aircraft, civil and power plant structures. In real life components are subjected to cracking at many vulnerable locations such as the bolt holes. However, we do not consider for the presence of multiple cracks. Unlike components with a single crack, these components are difficult to predict. When two cracks approach one another, their stress fields influence each other and produce enhancing or shielding effect depending on the position of the cracks. In the present study, numerical studies on fracture analysis have been conducted by using the developed code based on the modified virtual crack closure integral (MVCCI) technique and finite element analysis (FEA) software ABAQUS for computing SIF of plates with multiple cracks. Various parametric studies have been carried out and the results have been compared with literature where ever available and also with the solution, obtained by using ABAQUS. By conducting extensive numerical studies expressions for SIF have been obtained for collinear cracks and non-aligned cracks.

Keywords: Crack interaction, Fracture mechanics, Multiple site damage, stress intensity factor, collinear cracks, non-aligned cracks.

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Authors: Rakesh Prajapati, Purvik Patel, Hardik Patel

Abstract:

Productivity and quality are two important aspects that have become great concerns in today’s competitive global market. Every production/manufacturing unit mainly focuses on these areas in relation to the process, as well as the product developed. The electrical discharge machining (EDM) process, even now it is an experience process, wherein the selected parameters are still often far from the maximum, and at the same time selecting optimization parameters is costly and time consuming. Material Removal Rate (MRR) during the process has been considered as a productivity estimate with the aim to maximize it, with an intention of minimizing surface roughness taken as most important output parameter. These two opposites in nature requirements have been simultaneously satisfied by selecting an optimal process environment (optimal parameter setting). Objective function is obtained by Regression Analysis and Analysis of Variance. Then objective function is optimized using Genetic Algorithm technique. The model is shown to be effective; MRR and Surface Roughness improved using optimized machining parameters.

Keywords: Material removal rate, TWR, OC, DOE, ANOVA, MINITAB.

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Authors: Badr M. Alshammari, T. Guesmi

Abstract:

In this paper, the concept of a non-dominated sorting multi-objective particle swarm optimization with local search (NSPSO-LS) is presented for the optimal design of multimachine power system stabilizers (PSSs). The controller design is formulated as an optimization problem in order to shift the system electromechanical modes in a pre-specified region in the s-plan. A composite set of objective functions comprising the damping factor and the damping ratio of the undamped and lightly damped electromechanical modes is considered. The performance of the proposed optimization algorithm is verified for the 3-machine 9-bus system. Simulation results based on eigenvalue analysis and nonlinear time-domain simulation show the potential and superiority of the NSPSO-LS algorithm in tuning PSSs over a wide range of loading conditions and large disturbance compared to the classic PSO technique and genetic algorithms.

Keywords: Multi-objective optimization, particle swarm optimization, power system stabilizer, low frequency oscillations.

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Authors: C. Wan, A. Mita

Abstract:

This paper proposes a novel system for monitoring the health of underground pipelines. Some of these pipelines transport dangerous contents and any damage incurred might have catastrophic consequences. However, most of these damage are unintentional and usually a result of surrounding construction activities. In order to prevent these potential damages, monitoring systems are indispensable. This paper focuses on acoustically recognizing road cutters since they prelude most construction activities in modern cities. Acoustic recognition can be easily achieved by installing a distributed computing sensor network along the pipelines and using smart sensors to “listen" for potential threat; if there is a real threat, raise some form of alarm. For efficient pipeline monitoring, a novel monitoring approach is proposed. Principal Component Analysis (PCA) was studied and applied. Eigenvalues were regarded as the special signature that could characterize a sound sample, and were thus used for the feature vector for sound recognition. The denoising ability of PCA could make it robust to noise interference. One class SVM was used for classifier. On-site experiment results show that the proposed PCA and SVM based acoustic recognition system will be very effective with a low tendency for raising false alarms.

Keywords: One class SVM, pipeline monitoring system, principal component analysis, sound recognition, third party damage.

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Authors: Anujendra, Parag Kumar Guha Thakurta

Abstract:

The data transmission between mobile hosts and base stations (BSs) in Mobile networks are often vulnerable to failure. So, efficient link connectivity, in terms of the services of both base stations and communication channels of the network, is required in wireless mobile networks to achieve highly reliable data transmission. In addition, it is observed that the number of blocked hosts is increased due to insufficient number of channels during heavy load in the network. Under such scenario, the channels are allocated accordingly to offer a reliable communication at any given time. Therefore, a reliability-based channel allocation model with acceptable system performance is proposed as a MOO problem in this paper. Two conflicting parameters known as Resource Reuse factor (RRF) and the number of blocked calls are optimized under reliability constraint in this problem. The solution to such MOO problem is obtained through NSGA-II (Non dominated Sorting Genetic Algorithm). The effectiveness of the proposed model in this work is shown with a set of experimental results.

Keywords: Base station, channel, GA, Pareto-optimal, reliability.

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Authors: Benjapol Auprasert, Yachai Limpiyakorn

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Measuring the complexity of software has been an insoluble problem in software engineering. Complexity measures can be used to predict critical information about testability, reliability, and maintainability of software systems from automatic analysis of the source code. During the past few years, many complexity measures have been invented based on the emerging Cognitive Informatics discipline. These software complexity measures, including cognitive functional size, lend themselves to the approach of the total cognitive weights of basic control structures such as loops and branches. This paper shows that the current existing calculation method can generate different results that are algebraically equivalence. However, analysis of the combinatorial meanings of this calculation method shows significant flaw of the measure, which also explains why it does not satisfy Weyuker's properties. Based on the findings, improvement directions, such as measures fusion, and cumulative variable counting scheme are suggested to enhance the effectiveness of cognitive complexity measures.

Keywords: Cognitive Complexity Measure, Cognitive Weight of Basic Control Structure, Counting Rules, Cumulative Variable Counting Scheme.

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Authors: Anton V. Doroshin

Abstract:

This article contains a description of main ideas for the attitude reorientation of spacecraft (small dual-spin spacecraft, nanosatellites) using properties of its chaotic attitude motion under the action of internal perturbations. The considering method based on intentional initiations of chaotic modes of the attitude motion with big amplitudes of the nutation oscillations, and also on the redistributions of the angular momentum between coaxial bodies of the dual-spin spacecraft (DSSC), which perform in the purpose of system’s phase space changing.

Keywords: Spacecraft, Attitude Dynamics and Control, Chaos.

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Authors: Mukul Bandodkar, Virat Chourasia

Abstract:

Visually impaired people find it extremely difficult to acquire basic and vital information necessary for their living. Therefore, they are at a very high risk of being socially excluded as a result of poor access to information. In recent years, several attempts have been made in improving the communication methods for visually impaired people which involve tactile sensation such as finger Braille, manual alphabets and the print on palm method and several other electronic devices. But, there are some problems which arise in such methods such as lack of privacy and lack of compatibility to computer environment. This paper describes a low cost Braille hand glove for blind people using slot sensors and vibration motors with the help of which they can read and write emails, text messages and read e-books. This glove allows the person to type characters based on different Braille combination using six slot sensors. The vibration in six different positions of the glove which matches to the Braille code allows them to read characters.

Keywords: Braille, Braille Hand-Glove, Slot sensors, Vibration motors.

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Authors: Mert Bal, Hayri Sever, Oya Kalıpsız

Abstract:

Medical Decision Support Systems (MDSSs) are sophisticated, intelligent systems that can provide inference due to lack of information and uncertainty. In such systems, to model the uncertainty various soft computing methods such as Bayesian networks, rough sets, artificial neural networks, fuzzy logic, inductive logic programming and genetic algorithms and hybrid methods that formed from the combination of the few mentioned methods are used. In this study, symptom-disease relationships are presented by a framework which is modeled with a formal concept analysis and theory, as diseases, objects and attributes of symptoms. After a concept lattice is formed, Bayes theorem can be used to determine the relationships between attributes and objects. A discernibility relation that forms the base of the rough sets can be applied to attribute data sets in order to reduce attributes and decrease the complexity of computation.

Keywords: Formal Concept Analysis, Rough Set Theory, Granular Computing, Medical Decision Support System.

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Authors: Wen-Chi Hou, Cheng Luo, Zhewei Jiang, Feng Yan

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In this research, we propose to use the discrete cosine transform to approximate the cumulative distributions of data cube cells- values. The cosine transform is known to have a good energy compaction property and thus can approximate data distribution functions easily with small number of coefficients. The derived estimator is accurate and easy to update. We perform experiments to compare its performance with a well-known technique - the (Haar) wavelet. The experimental results show that the cosine transform performs much better than the wavelet in estimation accuracy, speed, space efficiency, and update easiness.

Keywords: DCT, Data Cube

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Authors: Hong Yi Huang, Wei Ti Kuo, Yi You Huang

Abstract:

Non-viral gene carriers composed of biodegradable polymers or lipids have been considered as a safer alternative for gene carriers over viral vectors. We have developed multi-functional nano-micelles for both drug and gene delivery application. Polyethyleneimine (PEI) was modified by grafting stearic acid (SA) and formulated to polymeric micelles (PEI-SA) with positive surface charge for gene and drug delivery. Our results showed that PEI-SA micelles provided high siRNA binding efficiency. In addition, siRNA delivered by PEI-SA carriers also demonstrated significantly high cellular uptake even in the presence of serum proteins. The post-transcriptional gene silencing efficiency was greatly improved by the polyplex formulated by 10k PEI-SA/siRNA. The amphiphilic structure of PEI-SA micelles provided advantages for multifunctional tasks; where the hydrophilic shell modified with cationic charges can electrostatically interact with DNA or siRNA, and the hydrophobic core can serve as payloads for hydrophobic drugs, making it a promising multifunctional vehicle for both genetic and chemotherapy application.

Keywords: polyethyleneimine, gene delivery, micelles, siRNA

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