Investigating the Effect of Velocity Inlet and Carrying Fluid on the Flow inside Coronary Artery

Authors: Mohammadreza Nezamirad, Nasim Sabetpour, Azadeh Yazdi, Amirmasoud Hamedi

Abstract:

In this study OpenFOAM 4.4.2 was used to investigate flow inside the coronary artery of the heart. This step is the first step of our future project, which is to include conjugate heat transfer of the heart with three main coronary arteries. Three different velocities were used as inlet boundary conditions to see the effect of velocity increase on velocity, pressure, and wall shear of the coronary artery. Also, three different fluids, namely the University of Wisconsin solution, gelatin, and blood was used to investigate the effect of different fluids on flow inside the coronary artery. A code based on Reynolds Stress Navier Stokes (RANS) equations was written and implemented with the real boundary condition that was calculated based on MRI images. In order to improve the accuracy of the current numerical scheme, hex dominant mesh is utilized. When the inlet velocity increases to 0.5 m/s, velocity, wall shear stress, and pressure increase at the narrower parts.

Keywords: CFD, heart, simulation, OpenFOAM.

References:

[1] Vikas Kannojiya, Arup Kumar Das, Prasanta Kumar Das. (2021) Simulation of Blood as Fluid: A Review from Rheological Aspects. IEEE Reviews in Biomedical Engineering 14, 327-341.
[2] Siamak N. Doost, Liang Zhong, Boyang Su, Yosry S. Morsi. (2016) The numerical analysis of non-Newtonian blood flow in human patient-specific left ventricle. Computer Methods and Programs in Biomedicine 127, 232-247.
[3] Collins M. J., Moainie S. L., Griffith B. P., and Poston R. S., "Preserving and Evaluating Hearts with ex vivo Machine Perfusion: an Avenue to Improve Early Graft Performance and Expand the Donor," European Journal of Cardio-thoracic Surgery, 34 318—325, 2008.
[4] Garry Leonard Howe, ”A MULTIPHYSICS SIMULATION OF A CORONARY ARTERY”, master thesis, California Polytechnic State University.
[5] Sengupta, D., Kahn, A. M., Burns, J. C., Sankaran, S., Shadden, S. C., & Marsden, A. L. (2012). Image-based modeling of hemodynamics in coronary artery aneurysms caused by Kawasaki disease. Biomechanics and modeling in mechanobiology, 11(6), 915-932.