Search results for: rapid complex algorithm prototyping.
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 5316

Search results for: rapid complex algorithm prototyping.

4206 Space Vector PWM Simulation for Three Phase DC/AC Inverter

Authors: M. Kubeitari, A. Alhusayn, M. Alnahar

Abstract:

Space Vector Pulse Width Modulation SVPWM is one of the most used techniques to generate sinusoidal voltage and current due to its facility and efficiency with low harmonics distortion. This algorithm is specially used in power electronic applications. This paper describes simulation algorithm of SVPWM & SPWM using MatLab/simulink environment. It also implements a closed loop three phases DC-AC converter controlling its outputs voltages amplitude and frequency using MatLab. Also comparison between SVPWM & SPWM results is given.

Keywords: DC-AC Converter, MatLab, SPWM, SVPWM, Vref - rotating frame.

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4205 Malicious Vehicle Detection Using Monitoring Algorithm in Vehicular Adhoc Networks

Authors: S. Padmapriya

Abstract:

Vehicular Adhoc Networks (VANETs), a subset of Mobile Adhoc Networks (MANETs), refers to a set of smart vehicles used for road safety. This vehicle provides communication services among one another or with the Road Side Unit (RSU). Security is one of the most critical issues related to VANET as the information transmitted is distributed in an open access environment. As each vehicle is not a source of all messages, most of the communication depends on the information received from other vehicles. To protect VANET from malicious action, each vehicle must be able to evaluate, decide and react locally on the information received from other vehicles. Therefore, message verification is more challenging in VANET because of the security and privacy concerns of the participating vehicles. To overcome security threats, we propose Monitoring Algorithm that detects malicious nodes based on the pre-selected threshold value. The threshold value is compared with the distrust value which is inherently tagged with each vehicle. The proposed Monitoring Algorithm not only detects malicious vehicles, but also isolates the malicious vehicles from the network. The proposed technique is simulated using Network Simulator2 (NS2) tool. The simulation result illustrated that the proposed Monitoring Algorithm outperforms the existing algorithms in terms of malicious node detection, network delay, packet delivery ratio and throughput, thereby uplifting the overall performance of the network.

Keywords: VANET, security, malicious vehicle detection, threshold value, distrust value.

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4204 Optimizing Boiler Combustion System in a Petrochemical Plant Using Neuro-Fuzzy Inference System and Genetic Algorithm

Authors: Yul Y. Nazaruddin, Anas Y. Widiaribowo, Satriyo Nugroho

Abstract:

Boiler is one of the critical unit in a petrochemical plant. Steam produced by the boiler is used for various processes in the plant such as urea and ammonia plant. An alternative method to optimize the boiler combustion system is presented in this paper. Adaptive Neuro-Fuzzy Inference System (ANFIS) approach is applied to model the boiler using real-time operational data collected from a boiler unit of the petrochemical plant. Nonlinear equation obtained is then used to optimize the air to fuel ratio using Genetic Algorithm, resulting an optimal ratio of 15.85. This optimal ratio is then maintained constant by ratio controller designed using inverse dynamics based on ANFIS. As a result, constant value of oxygen content in the flue gas is obtained which indicates more efficient combustion process.

Keywords: ANFIS, boiler, combustion process, genetic algorithm, optimization.

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4203 Hot-Spot Blob Merging for Real-Time Image Segmentation

Authors: K. Kraus, M. Uiberacker, O. Martikainen, R. Reda

Abstract:

One of the major, difficult tasks in automated video surveillance is the segmentation of relevant objects in the scene. Current implementations often yield inconsistent results on average from frame to frame when trying to differentiate partly occluding objects. This paper presents an efficient block-based segmentation algorithm which is capable of separating partly occluding objects and detecting shadows. It has been proven to perform in real time with a maximum duration of 47.48 ms per frame (for 8x8 blocks on a 720x576 image) with a true positive rate of 89.2%. The flexible structure of the algorithm enables adaptations and improvements with little effort. Most of the parameters correspond to relative differences between quantities extracted from the image and should therefore not depend on scene and lighting conditions. Thus presenting a performance oriented segmentation algorithm which is applicable in all critical real time scenarios.

Keywords: Image segmentation, Model-based, Region growing, Blob Analysis, Occlusion, Shadow detection, Intelligent videosurveillance.

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4202 A GA-Based Role Assignment Approach for Web-based Cooperative Learning Environments

Authors: Yi-Chun Chang, Jian-Wei Li

Abstract:

Web-based cooperative learning focuses on (1) the interaction and the collaboration of community members, and (2) the sharing and the distribution of knowledge and expertise by network technology to enhance learning performance. Numerous research literatures related to web-based cooperative learning have demonstrated that cooperative scripts have a positive impact to specify, sequence, and assign cooperative learning activities. Besides, literatures have indicated that role-play in web-based cooperative learning environments enhances two or more students to work together toward the completion of a common goal. Since students generally do not know each other and they lack the face-to-face contact that is necessary for the negotiation of assigning group roles in web-based cooperative learning environments, this paper intends to further extend the application of genetic algorithm (GA) and propose a GA-based algorithm to tackle the problem of role assignment in web-based cooperative learning environments, which not only saves communication costs but also reduces conflict between group members in negotiating role assignments.

Keywords: genetic algorithm (GA), role assignment, role-play; web-based cooperative learning.

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4201 Analysis of Cooperative Learning Behavior Based on the Data of Students' Movement

Authors: Wang Lin, Li Zhiqiang

Abstract:

The purpose of this paper is to analyze the cooperative learning behavior pattern based on the data of students' movement. The study firstly reviewed the cooperative learning theory and its research status, and briefly introduced the k-means clustering algorithm. Then, it used clustering algorithm and mathematical statistics theory to analyze the activity rhythm of individual student and groups in different functional areas, according to the movement data provided by 10 first-year graduate students. It also focused on the analysis of students' behavior in the learning area and explored the law of cooperative learning behavior. The research result showed that the cooperative learning behavior analysis method based on movement data proposed in this paper is feasible. From the results of data analysis, the characteristics of behavior of students and their cooperative learning behavior patterns could be found.

Keywords: Behavior pattern, cooperative learning, data analyze, K-means clustering algorithm.

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4200 GA Based Optimal Feature Extraction Method for Functional Data Classification

Authors: Jun Wan, Zehua Chen, Yingwu Chen, Zhidong Bai

Abstract:

Classification is an interesting problem in functional data analysis (FDA), because many science and application problems end up with classification problems, such as recognition, prediction, control, decision making, management, etc. As the high dimension and high correlation in functional data (FD), it is a key problem to extract features from FD whereas keeping its global characters, which relates to the classification efficiency and precision to heavens. In this paper, a novel automatic method which combined Genetic Algorithm (GA) and classification algorithm to extract classification features is proposed. In this method, the optimal features and classification model are approached via evolutional study step by step. It is proved by theory analysis and experiment test that this method has advantages in improving classification efficiency, precision and robustness whereas using less features and the dimension of extracted classification features can be controlled.

Keywords: Classification, functional data, feature extraction, genetic algorithm, wavelet.

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4199 Mining Network Data for Intrusion Detection through Naïve Bayesian with Clustering

Authors: Dewan Md. Farid, Nouria Harbi, Suman Ahmmed, Md. Zahidur Rahman, Chowdhury Mofizur Rahman

Abstract:

Network security attacks are the violation of information security policy that received much attention to the computational intelligence society in the last decades. Data mining has become a very useful technique for detecting network intrusions by extracting useful knowledge from large number of network data or logs. Naïve Bayesian classifier is one of the most popular data mining algorithm for classification, which provides an optimal way to predict the class of an unknown example. It has been tested that one set of probability derived from data is not good enough to have good classification rate. In this paper, we proposed a new learning algorithm for mining network logs to detect network intrusions through naïve Bayesian classifier, which first clusters the network logs into several groups based on similarity of logs, and then calculates the prior and conditional probabilities for each group of logs. For classifying a new log, the algorithm checks in which cluster the log belongs and then use that cluster-s probability set to classify the new log. We tested the performance of our proposed algorithm by employing KDD99 benchmark network intrusion detection dataset, and the experimental results proved that it improves detection rates as well as reduces false positives for different types of network intrusions.

Keywords: Clustering, detection rate, false positive, naïveBayesian classifier, network intrusion detection.

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4198 Uncertainty Multiple Criteria Decision Making Analysis for Stealth Combat Aircraft Selection

Authors: C. Ardil

Abstract:

Fuzzy set theory and its extensions (intuitionistic fuzzy sets, picture fuzzy sets, and neutrosophic sets) have been widely used to address imprecision and uncertainty in complex decision-making. However, they may struggle with inherent indeterminacy and inconsistency in real-world situations. This study introduces uncertainty sets as a promising alternative, offering a structured framework for incorporating both types of uncertainty into decision-making processes.This work explores the theoretical foundations and applications of uncertainty sets. A novel decision-making algorithm based on uncertainty set-based proximity measures is developed and demonstrated through a practical application: selecting the most suitable stealth combat aircraft.

The results highlight the effectiveness of uncertainty sets in ranking alternatives under uncertainty. Uncertainty sets offer several advantages, including structured uncertainty representation, robust ranking mechanisms, and enhanced decision-making capabilities due to their ability to account for ambiguity.Future research directions are also outlined, including comparative analysis with existing MCDM methods under uncertainty, sensitivity analysis to assess the robustness of rankings,and broader application to various MCDM problems with diverse complexities. By exploring these avenues, uncertainty sets can be further established as a valuable tool for navigating uncertainty in complex decision-making scenarios.

Keywords: Uncertainty set, stealth combat aircraft selection multiple criteria decision-making analysis, MCDM, uncertainty proximity analysis

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4197 Constraint Based Frequent Pattern Mining Technique for Solving GCS Problem

Authors: First G.M. Karthik, Second Ramachandra.V.Pujeri, Dr.

Abstract:

Generalized Center String (GCS) problem are generalized from Common Approximate Substring problem and Common substring problems. GCS are known to be NP-hard allowing the problems lies in the explosion of potential candidates. Finding longest center string without concerning the sequence that may not contain any motifs is not known in advance in any particular biological gene process. GCS solved by frequent pattern-mining techniques and known to be fixed parameter tractable based on the fixed input sequence length and symbol set size. Efficient method known as Bpriori algorithms can solve GCS with reasonable time/space complexities. Bpriori 2 and Bpriori 3-2 algorithm are been proposed of any length and any positions of all their instances in input sequences. In this paper, we reduced the time/space complexity of Bpriori algorithm by Constrained Based Frequent Pattern mining (CBFP) technique which integrates the idea of Constraint Based Mining and FP-tree mining. CBFP mining technique solves the GCS problem works for all center string of any length, but also for the positions of all their mutated copies of input sequence. CBFP mining technique construct TRIE like with FP tree to represent the mutated copies of center string of any length, along with constraints to restraint growth of the consensus tree. The complexity analysis for Constrained Based FP mining technique and Bpriori algorithm is done based on the worst case and average case approach. Algorithm's correctness compared with the Bpriori algorithm using artificial data is shown.

Keywords: Constraint Based Mining, FP tree, Data mining, GCS problem, CBFP mining technique.

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4196 Web 2.0 in Higher Education: The Instructors’ Acceptance in Higher Educational Institutes in Kingdom of Bahrain

Authors: Amal M. Alrayes, Hayat M. Ali

Abstract:

Since the beginning of distance education with the rapid evolution of technology, the social network plays a vital role in the educational process to enforce the interaction been the learners and teachers. There are many Web 2.0 technologies, services and tools designed for educational purposes. This research aims to investigate instructors’ acceptance towards web-based learning systems in higher educational institutes in Kingdom of Bahrain. Questionnaire is used to investigate the instructors’ usage of Web 2.0 and the factors affecting their acceptance. The results confirm that instructors had high accessibility to such technologies. However, patterns of use were complex. Whilst most expressed interest in using online technologies to support learning activities, learners seemed cautious about other values associated with web-based system, such as the shared construction of knowledge in a public format. The research concludes that there are main factors that affect instructors’ adoption which are security, performance expectation, perceived benefits, subjective norm, and perceived usefulness.

Keywords: Web 2.0, Higher education, Acceptance, Students’ perception.

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4195 Segmentation of Gray Scale Images of Dropwise Condensation on Textured Surfaces

Authors: Helene Martin, Solmaz Boroomandi Barati, Jean-Charles Pinoli, Stephane Valette, Yann Gavet

Abstract:

In the present work we developed an image processing algorithm to measure water droplets characteristics during dropwise condensation on pillared surfaces. The main problem in this process is the similarity between shape and size of water droplets and the pillars. The developed method divides droplets into four main groups based on their size and applies the corresponding algorithm to segment each group. These algorithms generate binary images of droplets based on both their geometrical and intensity properties. The information related to droplets evolution during time including mean radius and drops number per unit area are then extracted from the binary images. The developed image processing algorithm is verified using manual detection and applied to two different sets of images corresponding to two kinds of pillared surfaces.

Keywords: Dropwise condensation, textured surface, image processing, watershed.

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4194 An Algorithm for Autonomous Aerial Navigation using MATLAB® Mapping Tool Box

Authors: Mansoor Ahsan, Suhail Akhtar, Adnan Ali, Farrukh Mazhar, Muddssar Khalid

Abstract:

In the present era of aviation technology, autonomous navigation and control have emerged as a prime area of active research. Owing to the tremendous developments in the field, autonomous controls have led today’s engineers to claim that future of aerospace vehicle is unmanned. Development of guidance and navigation algorithms for an unmanned aerial vehicle (UAV) is an extremely challenging task, which requires efforts to meet strict, and at times, conflicting goals of guidance and control. In this paper, aircraft altitude and heading controllers and an efficient algorithm for self-governing navigation using MATLAB® mapping toolbox is presented which also enables loitering of a fixed wing UAV over a specified area. For this purpose, a nonlinear mathematical model of a UAV is used. The nonlinear model is linearized around a stable trim point and decoupled for controller design. The linear controllers are tested on the nonlinear aircraft model and navigation algorithm is subsequently developed for for autonomous flight of the UAV. The results are presented for trajectory controllers and waypoint based navigation. Our investigation reveals that MATLAB® mapping toolbox can be exploited to successfully deliver an efficient algorithm for autonomous aerial navigation for a UAV.

Keywords: Navigation, trajectory-control, unmanned aerial vehicle, PID-control, MATLAB® mapping toolbox.

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4193 Optimum Design of Trusses by Cuckoo Search

Authors: M. Saravanan, J. Raja Murugadoss, V. Jayanthi

Abstract:

Optimal design of structure has a main role in reduction of material usage which leads to deduction in the final cost of construction projects. Evolutionary approaches are found to be more successful techniques for solving size and shape structural optimization problem since it uses a stochastic random search instead of a gradient search. By reviewing the recent literature works the problem found was the optimization of weight. A new meta-heuristic algorithm called as Cuckoo Search (CS) Algorithm has used for the optimization of the total weight of the truss structures. This paper has used set of 10 bars and 25 bars trusses for the testing purpose. The main objective of this work is to reduce the number of iterations, weight and the total time consumption. In order to demonstrate the effectiveness of the present method, minimum weight design of truss structures is performed and the results of the CS are compared with other algorithms.

Keywords: Cuckoo search algorithm, levy’s flight, meta-heuristic, optimal weight.

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4192 A CT-based Monte Carlo Dose Calculations for Proton Therapy Using a New Interface Program

Authors: A. Esmaili Torshabi, A. Terakawa, K. Ishii, H. Yamazaki, S. Matsuyama, Y. Kikuchi, M. Nakhostin, H. Sabet, A. Ishizaki, W. Yamashita, T. Togashi, J. Arikawa, H. Akiyama, K. Koyata

Abstract:

The purpose of this study is to introduce a new interface program to calculate a dose distribution with Monte Carlo method in complex heterogeneous systems such as organs or tissues in proton therapy. This interface program was developed under MATLAB software and includes a friendly graphical user interface with several tools such as image properties adjustment or results display. Quadtree decomposition technique was used as an image segmentation algorithm to create optimum geometries from Computed Tomography (CT) images for dose calculations of proton beam. The result of the mentioned technique is a number of nonoverlapped squares with different sizes in every image. By this way the resolution of image segmentation is high enough in and near heterogeneous areas to preserve the precision of dose calculations and is low enough in homogeneous areas to reduce the number of cells directly. Furthermore a cell reduction algorithm can be used to combine neighboring cells with the same material. The validation of this method has been done in two ways; first, in comparison with experimental data obtained with 80 MeV proton beam in Cyclotron and Radioisotope Center (CYRIC) in Tohoku University and second, in comparison with data based on polybinary tissue calibration method, performed in CYRIC. These results are presented in this paper. This program can read the output file of Monte Carlo code while region of interest is selected manually, and give a plot of dose distribution of proton beam superimposed onto the CT images.

Keywords: Monte Carlo, CT images, Quadtree decomposition, Interface program, Proton beam

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4191 An Algorithm for Determining the Arrival Behavior of a Secondary User to a Base Station in Cognitive Radio Networks

Authors: Danilo López, Edwin Rivas, Leyla López

Abstract:

This paper presents the development of an algorithm that predicts the arrival of a secondary user (SU) to a base station (BS) in a cognitive network based on infrastructure, requesting a Best Effort (BE) or Real Time (RT) type of service with a determined bandwidth (BW) implementing neural networks. The algorithm dynamically uses a neural network construction technique using the geometric pyramid topology and trains a Multilayer Perceptron Neural Networks (MLPNN) based on the historical arrival of an SU to estimate future applications. This will allow efficiently managing the information in the BS, since it precedes the arrival of the SUs in the stage of selection of the best channel in CRN. As a result, the software application determines the probability of arrival at a future time point and calculates the performance metrics to measure the effectiveness of the predictions made.

Keywords: Cognitive radio, MLPNN, base station, prediction, best effort, real time.

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4190 Force Analysis of an Automated Rapid Maxillary Expansion (ARME) Appliance

Authors: A.A.Sharizli, N.A.Abu Osman, A.A.Saifizul

Abstract:

An Automated Rapid Maxillary Expander (ARME) is a specially designed microcontroller-based orthodontic appliance to overcome the shortcomings imposed by the traditional maxillary expansion appliances. This new device is operates by automatically widening the maxilla (upper jaw) by expanding the midpalatal suture [1]. The ARME appliance that has been developed is a combination of modified butterfly expander appliance, micro gear, micro motor, and microcontroller to automatically produce light and continuous pressure to expand the maxilla. For this study, the functionality of the system is verified through laboratory tests by measure the forced applied to the teeth each time the maxilla expands. The laboratory test results show that the developed appliance meets the desired performance specifications consistently.

Keywords: Maxillary Expansion, Microcontroller, Automated, Orthodontist, Force Analysis.

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4189 Integrated ACOR/IACOMV-R-SVM Algorithm

Authors: Hiba Basim Alwan, Ku Ruhana Ku-Mahamud

Abstract:

A direction for ACO is to optimize continuous and mixed (discrete and continuous) variables in solving problems with various types of data. Support Vector Machine (SVM), which originates from the statistical approach, is a present day classification technique. The main problems of SVM are selecting feature subset and tuning the parameters. Discretizing the continuous value of the parameters is the most common approach in tuning SVM parameters. This process will result in loss of information which affects the classification accuracy. This paper presents two algorithms that can simultaneously tune SVM parameters and select the feature subset. The first algorithm, ACOR-SVM, will tune SVM parameters, while the second IACOMV-R-SVM algorithm will simultaneously tune SVM parameters and select the feature subset. Three benchmark UCI datasets were used in the experiments to validate the performance of the proposed algorithms. The results show that the proposed algorithms have good performances as compared to other approaches.

Keywords: Continuous ant colony optimization, incremental continuous ant colony, simultaneous optimization, support vector machine.

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4188 Continuous Feature Adaptation for Non-Native Speech Recognition

Authors: Y. Deng, X. Li, C. Kwan, B. Raj, R. Stern

Abstract:

The current speech interfaces in many military applications may be adequate for native speakers. However, the recognition rate drops quite a lot for non-native speakers (people with foreign accents). This is mainly because the nonnative speakers have large temporal and intra-phoneme variations when they pronounce the same words. This problem is also complicated by the presence of large environmental noise such as tank noise, helicopter noise, etc. In this paper, we proposed a novel continuous acoustic feature adaptation algorithm for on-line accent and environmental adaptation. Implemented by incremental singular value decomposition (SVD), the algorithm captures local acoustic variation and runs in real-time. This feature-based adaptation method is then integrated with conventional model-based maximum likelihood linear regression (MLLR) algorithm. Extensive experiments have been performed on the NATO non-native speech corpus with baseline acoustic model trained on native American English. The proposed feature-based adaptation algorithm improved the average recognition accuracy by 15%, while the MLLR model based adaptation achieved 11% improvement. The corresponding word error rate (WER) reduction was 25.8% and 2.73%, as compared to that without adaptation. The combined adaptation achieved overall recognition accuracy improvement of 29.5%, and WER reduction of 31.8%, as compared to that without adaptation.

Keywords: speaker adaptation; environment adaptation; robust speech recognition; SVD; non-native speech recognition

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4187 Phytopathology Prediction in Dry Soil Using Artificial Neural Networks Modeling

Authors: F. Allag, S. Bouharati, M. Belmahdi, R. Zegadi

Abstract:

The rapid expansion of deserts in recent decades as a result of human actions combined with climatic changes has highlighted the necessity to understand biological processes in arid environments. Whereas physical processes and the biology of flora and fauna have been relatively well studied in marginally used arid areas, knowledge of desert soil micro-organisms remains fragmentary. The objective of this study is to conduct a diversity analysis of bacterial communities in unvegetated arid soils. Several biological phenomena in hot deserts related to microbial populations and the potential use of micro-organisms for restoring hot desert environments. Dry land ecosystems have a highly heterogeneous distribution of resources, with greater nutrient concentrations and microbial densities occurring in vegetated than in bare soils. In this work, we found it useful to use techniques of artificial intelligence in their treatment especially artificial neural networks (ANN). The use of the ANN model, demonstrate his capability for addressing the complex problems of uncertainty data.

Keywords: Desert soil, Climatic changes, Bacteria, Vegetation, Artificial neural networks.

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4186 A Context-Sensitive Algorithm for Media Similarity Search

Authors: Guang-Ho Cha

Abstract:

This paper presents a context-sensitive media similarity search algorithm. One of the central problems regarding media search is the semantic gap between the low-level features computed automatically from media data and the human interpretation of them. This is because the notion of similarity is usually based on high-level abstraction but the low-level features do not sometimes reflect the human perception. Many media search algorithms have used the Minkowski metric to measure similarity between image pairs. However those functions cannot adequately capture the aspects of the characteristics of the human visual system as well as the nonlinear relationships in contextual information given by images in a collection. Our search algorithm tackles this problem by employing a similarity measure and a ranking strategy that reflect the nonlinearity of human perception and contextual information in a dataset. Similarity search in an image database based on this contextual information shows encouraging experimental results.

Keywords: Context-sensitive search, image search, media search, similarity ranking, similarity search.

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4185 Accrual Based Scheduling for Cloud in Single and Multi Resource System: Study of Three Techniques

Authors: R. Santhosh, T. Ravichandran

Abstract:

This paper evaluates the accrual based scheduling for cloud in single and multi-resource system. Numerous organizations benefit from Cloud computing by hosting their applications. The cloud model provides needed access to computing with potentially unlimited resources. Scheduling is tasks and resources mapping to a certain optimal goal principle. Scheduling, schedules tasks to virtual machines in accordance with adaptable time, in sequence under transaction logic constraints. A good scheduling algorithm improves CPU use, turnaround time, and throughput. In this paper, three realtime cloud services scheduling algorithm for single resources and multiple resources are investigated. Experimental results show Resource matching algorithm performance to be superior for both single and multi-resource scheduling when compared to benefit first scheduling, Migration, Checkpoint algorithms.

Keywords: Cloud computing, Scheduling, Migration, Checkpoint, Resource Matching.

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4184 Design and Implementation of DC-DC Converter with Inc-Cond Algorithm

Authors: Mustafa Engin Basoğlu, Bekir Çakır

Abstract:

The most important component affecting the efficiency of photovoltaic power systems are solar panels. In other words, efficiency of these systems are significantly affected due to the being low efficiency of solar panel. Thus, solar panels should be operated under maximum power point conditions through a power converter. In this study, design of boost converter has been carried out with maximum power point tracking (MPPT) algorithm which is incremental conductance (Inc-Cond). By using this algorithm, importance of power converter in MPPT hardware design, impacts of MPPT operation have been shown. It is worth noting that initial operation point is the main criteria for determining the MPPT performance. In addition, it is shown that if value of load resistance is lower than critical value, failure operation is realized. For these analyzes, direct duty control is used for simplifying the control.

Keywords: Boost converter, Incremental Conductance (Inc- Cond), MPPT, Solar panel.

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4183 A Novel Multiplex Real-Time PCR Assay Using TaqMan MGB Probes for Rapid Detection of Trisomy 21

Authors: Mehrdad Hashemi, Mitra Behrooz Aghdam, Reza Mahdian, Ahmad Reza Kamyab

Abstract:

Cytogenetic analysis still remains the gold standard method for prenatal diagnosis of trisomy 21 (Down syndrome, DS). Nevertheless, the conventional cytogenetic analysis needs live cultured cells and is too time-consuming for clinical application. In contrast, molecular methods such as FISH, QF-PCR, MLPA and quantitative Real-time PCR are rapid assays with results available in 24h. In the present study, we have successfully used a novel MGB TaqMan probe-based real time PCR assay for rapid diagnosis of trisomy 21 status in Down syndrome samples. We have also compared the results of this molecular method with corresponding results obtained by the cytogenetic analysis. Blood samples obtained from DS patients (n=25) and normal controls (n=20) were tested by quantitative Real-time PCR in parallel to standard G-banding analysis. Genomic DNA was extracted from peripheral blood lymphocytes. A high precision TaqMan probe quantitative Real-time PCR assay was developed to determine the gene dosage of DSCAM (target gene on 21q22.2) relative to PMP22 (reference gene on 17p11.2). The DSCAM/PMP22 ratio was calculated according to the formula; ratio=2 -ΔΔCT. The quantitative Real-time PCR was able to distinguish between trisomy 21 samples and normal controls with the gene ratios of 1.49±0.13 and 1.03±0.04 respectively (p value <0.001). These results represent the presence of 3 copies of target gene in DS samples Vs 2 copies in normal controls. The results of quantitative Real-time PCR were in complete agreement with results of cytogenetic analysis. This study confirms previous reports regarding successful implementation of quantitative Real-time PCR for detection of trisomy 21. However, the assay has been improved by using MGB probes and more accurate data analysis. This assay, in particular, when performed in combination with another molecular assay such as QF-PCR or MLPA, can be used as a reliable technique for rapid prenatal diagnosis of trisomy 21.

Keywords: Trisomy 21, Real-time PCR, MGB-TaqMan Probes, Gene Dosage.

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4182 Multi-Objective Cellular Manufacturing System under Machines with Different Life-Cycle using Genetic Algorithm

Authors: N. Javadian, J. Rezaeian, Y. Maali

Abstract:

In this paper a multi-objective nonlinear programming model of cellular manufacturing system is presented which minimize the intercell movements and maximize the sum of reliability of cells. We present a genetic approach for finding efficient solutions to the problem of cell formation for products having multiple routings. These methods find the non-dominated solutions and according to decision makers prefer, the best solution will be chosen.

Keywords: Cellular Manufacturing, Genetic Algorithm, Multiobjective, Life-Cycle.

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4181 Analysis of Blind Decision Feedback Equalizer Convergence: Interest of a Soft Decision

Authors: S. Cherif, S. Marcos, M. Jaidane

Abstract:

In this paper the behavior of the decision feedback equalizers (DFEs) adapted by the decision-directed or the constant modulus blind algorithms is presented. An analysis of the error surface of the corresponding criterion cost functions is first developed. With the intention of avoiding the ill-convergence of the algorithm, the paper proposes to modify the shape of the cost function error surface by using a soft decision instead of the hard one. This was shown to reduce the influence of false decisions and to smooth the undesirable minima. Modified algorithms using the soft decision during a pseudo-training phase with an automatic switch to the properly tracking phase are then derived. Computer simulations show that these modified algorithms present better ability to avoid local minima than conventional ones.

Keywords: Blind DFEs, decision-directed algorithm, constant modulus algorithm, cost function analysis, convergence analysis, soft decision.

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4180 Research on the Relevance Feedback-based Image Retrieval in Digital Library

Authors: Rongtao Ding, Xinhao Ji, Linting Zhu

Abstract:

In recent years, the relevance feedback technology is regarded in content-based image retrieval. This paper suggests a neural networks feedback algorithm based on the radial basis function, coming to extract the semantic character of image. The results of experiment indicated that the performance of this relevance feedback is better than the feedback algorithm based on Single-RBF.

Keywords: Image retrieval, relevance feedback, radial basis function.

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4179 Wavelet based Image Registration Technique for Matching Dental x-rays

Authors: P. Ramprasad, H. C. Nagaraj, M. K. Parasuram

Abstract:

Image registration plays an important role in the diagnosis of dental pathologies such as dental caries, alveolar bone loss and periapical lesions etc. This paper presents a new wavelet based algorithm for registering noisy and poor contrast dental x-rays. Proposed algorithm has two stages. First stage is a preprocessing stage, removes the noise from the x-ray images. Gaussian filter has been used. Second stage is a geometric transformation stage. Proposed work uses two levels of affine transformation. Wavelet coefficients are correlated instead of gray values. Algorithm has been applied on number of pre and post RCT (Root canal treatment) periapical radiographs. Root Mean Square Error (RMSE) and Correlation coefficients (CC) are used for quantitative evaluation. Proposed technique outperforms conventional Multiresolution strategy based image registration technique and manual registration technique.

Keywords: Diagnostic imaging, geometric transformation, image registration, multiresolution.

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4178 Network Reconfiguration of Distribution System Using Artificial Bee Colony Algorithm

Authors: S. Ganesh

Abstract:

Power distribution systems typically have tie and sectionalizing switches whose states determine the topological configuration of the network. The aim of network reconfiguration of the distribution network is to minimize the losses for a load arrangement at a particular time. Thus the objective function is to minimize the losses of the network by satisfying the distribution network constraints. The various constraints are radiality, voltage limits and the power balance condition. In this paper the status of the switches is obtained by using Artificial Bee Colony (ABC) algorithm. ABC is based on a particular intelligent behavior of honeybee swarms. ABC is developed based on inspecting the behaviors of real bees to find nectar and sharing the information of food sources to the bees in the hive. The proposed methodology has three stages. In stage one ABC is used to find the tie switches, in stage two the identified tie switches are checked for radiality constraint and if the radilaity constraint is satisfied then the procedure is proceeded to stage three otherwise the process is repeated. In stage three load flow analysis is performed. The process is repeated till the losses are minimized. The ABC is implemented to find the power flow path and the Forward Sweeper algorithm is used to calculate the power flow parameters. The proposed methodology is applied for a 33–bus single feeder distribution network using MATLAB.

Keywords: Artificial Bee Colony (ABC) algorithm, Distribution system, Loss reduction, Network reconfiguration.

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4177 Performance Analysis of Proprietary and Non-Proprietary Tools for Regression Testing Using Genetic Algorithm

Authors: K. Hema Shankari, R. Thirumalaiselvi, N. V. Balasubramanian

Abstract:

The present paper addresses to the research in the area of regression testing with emphasis on automated tools as well as prioritization of test cases. The uniqueness of regression testing and its cyclic nature is pointed out. The difference in approach between industry, with business model as basis, and academia, with focus on data mining, is highlighted. Test Metrics are discussed as a prelude to our formula for prioritization; a case study is further discussed to illustrate this methodology. An industrial case study is also described in the paper, where the number of test cases is so large that they have to be grouped as Test Suites. In such situations, a genetic algorithm proposed by us can be used to reconfigure these Test Suites in each cycle of regression testing. The comparison is made between a proprietary tool and an open source tool using the above-mentioned metrics. Our approach is clarified through several tables.

Keywords: APFD metric, genetic algorithm, regression testing, RFT tool, test case prioritization, selenium tool.

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