Search results for: Artificial potential fields
2639 Inflammatory Markers in the Blood and Chronic Periodontitis
Authors: Saimir Heta, Ilma Robo, Nevila Alliu, Tea Meta
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Background: Plasma levels of inflammatory markers are the expression of the infectious wastes of existing periodontitis, as well as of existing inflammation everywhere in the body. Materials and Methods: The study consists of the clinical part of the measurement of inflammatory markers of 23 patients diagnosed with chronic periodontitis and the recording of parental periodontal parameters of patient periodontal status: hemorrhage index and probe values, before and 7-10 days after non-surgical periodontal treatment. Results: The level of fibrinogen drops according to the categorization of disease progression, active and passive, with the biggest % (18%-30%) at the fluctuation 10-20 mg/d. Fluctuations in fibrinogen level according to the age of patients in the range 0-10 mg/dL under 40 years and over 40 years was 13%-26%, in the range 10-20 mg/dL was 26%-22%, in the 20-40 mg/dL was 9%-4%. Conclusions: Non-surgical periodontal treatment significantly reduces the level of non-inflammatory markers in the blood. Oral health significantly reduces the potential source for periodontal bacteria, with the potential of promoting thromboembolism, through interaction between thrombocytes.
Keywords: Chronic periodontitis, atherosclerosis, risk factor, inflammatory markers.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5632638 Impact of Faults in Different Software Systems: A Survey
Authors: Neeraj Mohan, Parvinder S. Sandhu, Hardeep Singh
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Software maintenance is extremely important activity in software development life cycle. It involves a lot of human efforts, cost and time. Software maintenance may be further subdivided into different activities such as fault prediction, fault detection, fault prevention, fault correction etc. This topic has gained substantial attention due to sophisticated and complex applications, commercial hardware, clustered architecture and artificial intelligence. In this paper we surveyed the work done in the field of software maintenance. Software fault prediction has been studied in context of fault prone modules, self healing systems, developer information, maintenance models etc. Still a lot of things like modeling and weightage of impact of different kind of faults in the various types of software systems need to be explored in the field of fault severity.
Keywords: Fault prediction, Software Maintenance, Automated Fault Prediction, and Failure Mode Analysis
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20792637 An Efficient and Generic Hybrid Framework for High Dimensional Data Clustering
Authors: Dharmveer Singh Rajput , P. K. Singh, Mahua Bhattacharya
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Clustering in high dimensional space is a difficult problem which is recurrent in many fields of science and engineering, e.g., bioinformatics, image processing, pattern reorganization and data mining. In high dimensional space some of the dimensions are likely to be irrelevant, thus hiding the possible clustering. In very high dimensions it is common for all the objects in a dataset to be nearly equidistant from each other, completely masking the clusters. Hence, performance of the clustering algorithm decreases. In this paper, we propose an algorithmic framework which combines the (reduct) concept of rough set theory with the k-means algorithm to remove the irrelevant dimensions in a high dimensional space and obtain appropriate clusters. Our experiment on test data shows that this framework increases efficiency of the clustering process and accuracy of the results.Keywords: High dimensional clustering, sub-space, k-means, rough set, discernibility matrix.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19502636 Present Energy Scenario and Potentiality of Wind Energy in Bangladesh
Authors: Md. Alamgir Hossain, Md. Raju Ahmed
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Scarcity in energy sector is a major problem, which can hamper the growing development of a country. Bangladesh is one of the electricity-deprived countries; however, the energy demand of Bangladesh is increasing day by day. Due to the shortage of natural resources and environmental issues, many nations are now moving towards renewable energy. Among various form of renewable energy, wind energy is one of most potential source. In this paper, the present energy condition of Bangladesh is discussed and the necessity of moving towards renewable energy is clarified. The wind speed found at different locations at different heights and different years from the survey of several organizations are presented. Although, the results of installed low capacity wind turbines (from few kW to few tens of kW) operated by private or government organization at different places in Bangladesh are not so encouraging; however, it is shown that Bangladesh has a high potential of using large wind turbine (MW range) for capturing wind energy at different places. The present condition of wind energy in Bangladesh and other countries in the world are also presented to emphasize the requisite of moving towards wind energy.
Keywords: Renewable energy, wind speed, wind power, modern wind turbine, scarcity of power and gas crisis.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 35692635 Perspectives of Renewable Energy in 21st Century in India: Statistics and Estimation
Authors: Manoj Kumar, Rajesh Kumar
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With the favourable geographical conditions at Indian-subcontinent, it is suitable for flourishing renewable energy. Increasing amount of dependence on coal and other conventional sources is driving the world into pollution and depletion of resources. This paper presents the statistics of energy consumption and energy generation in Indian Sub-continent, which notifies us with the increasing energy demands surpassing energy generation. With the aggrandizement in demand for energy, usage of coal has increased, since the major portion of energy production in India is from thermal power plants. The increase in usage of thermal power plants causes pollution and depletion of reserves; hence, a paradigm shift to renewable sources is inevitable. In this work, the capacity and potential of renewable sources in India are analyzed. Based on the analysis of this work, future potential of these sources is estimated.Keywords: Energy consumption and generation, depletion of reserves, pollution, estimation, renewable sources.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 8192634 A New Method for Extracting Ocean Wave Energy Utilizing the Wave Shoaling Phenomenon
Authors: Shafiq R. Qureshi, Syed Noman Danish, Muhammad Saeed Khalid
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Fossil fuels are the major source to meet the world energy requirements but its rapidly diminishing rate and adverse effects on our ecological system are of major concern. Renewable energy utilization is the need of time to meet the future challenges. Ocean energy is the one of these promising energy resources. Threefourths of the earth-s surface is covered by the oceans. This enormous energy resource is contained in the oceans- waters, the air above the oceans, and the land beneath them. The renewable energy source of ocean mainly is contained in waves, ocean current and offshore solar energy. Very fewer efforts have been made to harness this reliable and predictable resource. Harnessing of ocean energy needs detail knowledge of underlying mathematical governing equation and their analysis. With the advent of extra ordinary computational resources it is now possible to predict the wave climatology in lab simulation. Several techniques have been developed mostly stem from numerical analysis of Navier Stokes equations. This paper presents a brief over view of such mathematical model and tools to understand and analyze the wave climatology. Models of 1st, 2nd and 3rd generations have been developed to estimate the wave characteristics to assess the power potential. A brief overview of available wave energy technologies is also given. A novel concept of on-shore wave energy extraction method is also presented at the end. The concept is based upon total energy conservation, where energy of wave is transferred to the flexible converter to increase its kinetic energy. Squeezing action by the external pressure on the converter body results in increase velocities at discharge section. High velocity head then can be used for energy storage or for direct utility of power generation. This converter utilizes the both potential and kinetic energy of the waves and designed for on-shore or near-shore application. Increased wave height at the shore due to shoaling effects increases the potential energy of the waves which is converted to renewable energy. This approach will result in economic wave energy converter due to near shore installation and more dense waves due to shoaling. Method will be more efficient because of tapping both potential and kinetic energy of the waves.Keywords: Energy Utilizing, Wave Shoaling Phenomenon
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 26692633 Extend of Self-Life of Potato Round Slices with Edible Coating, Green Tea and Ascorbic Acid
Authors: A. Spanou, P. Giannouli
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The effects of coatings based on sodium alginate (S.A) and carboxyl methyl cellulose (CMC) on the color and moisture characteristics of potato round slices were investigated. It is the first time that this combination of polysaccharides is used as edible coating which alone had the best performance as inhibitor of potato color discoloration during the storage of 15 days at 4oC. When ascorbic acid (AA) and green tea (GT) were added in the above edible coating its effects on potato round slices changed. The mixtures of sodium alginate and carboxyl methyl cellulose with ascorbic acid or with green tea behave as a potential moisture barrier, resulting to the extent of potato samples self–life. These data suggests that both GT and AA are potential inhibitors of dehydration in potatoes and not only natural antioxidants.
Keywords: Ascorbic acid, edible coating, green tea, moisture barrier.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 33982632 Transforming Personal Healthcare through Patient Engagement: An In-Depth Analysis of Tools and Methods for the Digital Age
Authors: Emily Hickmann, Peggy Richter, Maren Kählig, Hannes Schlieter
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Patient engagement is a cornerstone of high-quality care and essential for patients with chronic diseases to achieve improved health outcomes. Through digital transformation, possibilities to engage patients in their personal healthcare have multiplied. However, the exploitation of this potential is still lagging. To support the transmission of patient engagement theory into practice, this paper’s objective is to give a state-of-the-art overview of patient engagement tools and methods. A systematic literature review was conducted. Overall, 56 tools and methods were extracted and synthesized according to the four attributes of patient engagement, i.e., personalization, access, commitment, and therapeutic alliance. The results are discussed in terms of their potential to be implemented in digital health solutions under consideration of the “computers are social actors” (CASA) paradigm. It is concluded that digital health can catalyze patient engagement in practice, and a broad future research agenda is formulated.
Keywords: Chronic diseases, digitalization, patient-centeredness, patient empowerment, patient engagement.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 772631 A Numerical Simulation of the Indoor Air Flow
Authors: Karel Frana, Jianshun S. Zhang, Milos Muller
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The indoor airflow with a mixed natural/forced convection was numerically calculated using the laminar and turbulent approach. The Boussinesq approximation was considered for a simplification of the mathematical model and calculations. The results obtained, such as mean velocity fields, were successfully compared with experimental PIV flow visualizations. The effect of the distance between the cooled wall and the heat exchanger on the temperature and velocity distributions was calculated. In a room with a simple shape, the computational code OpenFOAM demonstrated an ability to numerically predict flow patterns. Furthermore, numerical techniques, boundary type conditions and the computational grid quality were examined. Calculations using the turbulence model k-omega had a significant effect on the results influencing temperature and velocity distributions.Keywords: natural and forced convections, numerical simulations, indoor airflows.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 32062630 Energy Performance of Buildings Due to Downscaled Seasonal Models
Authors: Anastasia K. Eleftheriadou, Athanasios Sfetsos, Nikolaos Gounaris
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The current paper presents an extensive bottom-up framework for assessing building sector-specific vulnerability to climate change: energy supply and demand. The research focuses on the application of downscaled seasonal models for estimating energy performance of buildings in Greece. The ARW-WRF model has been set-up and suitably parameterized to produce downscaled climatological fields for Greece, forced by the output of the CFSv2 model. The outer domain, D01/Europe, included 345 x 345 cells of horizontal resolution 20 x 20 km2 and the inner domain, D02/Greece, comprised 180 x 180 cells of 5 x 5 km2 horizontal resolution. The model run has been setup for a period with a forecast horizon of 6 months, storing outputs on a six hourly basis.Keywords: Urban environment, vulnerability, climate change, energy performance, seasonal forecast models.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17432629 Effect of Evaporator Temperature on the Performance of Water Desalination/Refrigeration Adsorption System Using AQSOA-ZO2
Authors: Peter G. Youssef, Saad M. Mahmoud, Raya K. Al-Dadah
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Many water desalination technologies have been developed but in general they are energy intensive and have high cost and adverse environmental impact. Recently, adsorption technology for water desalination has been investigated showing the potential of using low temperature waste heat (50-85oC) thus reducing energy consumption and CO2 emissions. This work mathematically compares the performance of an adsorption cycle that produces two useful effects namely, fresh water and cooling using two different adsorbents, silica-gel and an advanced zeolite material AQSOA-ZO2, produced by Mitsubishi plastics. It was found that at low chilled water temperatures, typically below 20oC, the AQSOA-Z02 is more efficient than silica-gel as the cycle can produce 5.8 m3 of fresh water per day and 50.1 Rton of cooling per tonne of AQSOA-ZO2. Above 20oC silica-gel is still better as the cycle production reaches 8.4 m3 per day and 62.4 Rton per tonne of silica-gel. These results show the potential of using the AQSOA-Z02 at low chilled water temperature for water desalination and cooling applications.Keywords: Adsorption, desalination, refrigeration, seawater.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 24812628 Thrust Vectoring Control of Supersonic Flow Through an Orifice Injector
Authors: Ibrahim Mnafeg, Azgal Abichou, Lotfi Beji
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Traditional mechanical control systems in thrust vectoring are efficient in rocket thrust guidance but their costs and their weights are excessive. The fluidic injection in the nozzle divergent constitutes an alternative procedure to achieve the goal. In this paper, we present a 3D analytical model for fluidic injection in a supersonic nozzle integrating an orifice. The fluidic vectoring uses a sonic secondary injection in the divergent. As a result, the flow and interaction between the main and secondary jet has built in order to express the pressure fields from which the forces and thrust vectoring are deduced. Under various separation criteria, the present analytical model results are compared with the existing numerical and experimental data from the literature.Keywords: Flow separation, Fluidic thrust vectoring, Nozzle, Secondary jet, Shock wave.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21292627 3D Modeling of Temperature by Finite Element in Machining with Experimental Authorization
Authors: P. Mottaghizadeh, M. Bagheri
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In the present paper, the three-dimensional temperature field of tool is determined during the machining and compared with experimental work on C45 workpiece using carbide cutting tool inserts. During the metal cutting operations, high temperature is generated in the tool cutting edge which influence on the rate of tool wear. Temperature is most important characteristic of machining processes; since many parameters such as cutting speed, surface quality and cutting forces depend on the temperature and high temperatures can cause high mechanical stresses which lead to early tool wear and reduce tool life. Therefore, considerable attention is paid to determine tool temperatures. The experiments are carried out for dry and orthogonal machining condition. The results show that the increase of tool temperature depends on depth of cut and especially cutting speed in high range of cutting conditions.Keywords: Finite element method, Machining, Temperature measurement, Thermal fields
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20752626 Using Pattern Search Methods for Minimizing Clustering Problems
Authors: Parvaneh Shabanzadeh, Malik Hj Abu Hassan, Leong Wah June, Maryam Mohagheghtabar
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Clustering is one of an interesting data mining topics that can be applied in many fields. Recently, the problem of cluster analysis is formulated as a problem of nonsmooth, nonconvex optimization, and an algorithm for solving the cluster analysis problem based on nonsmooth optimization techniques is developed. This optimization problem has a number of characteristics that make it challenging: it has many local minimum, the optimization variables can be either continuous or categorical, and there are no exact analytical derivatives. In this study we show how to apply a particular class of optimization methods known as pattern search methods to address these challenges. These methods do not explicitly use derivatives, an important feature that has not been addressed in previous studies. Results of numerical experiments are presented which demonstrate the effectiveness of the proposed method.Keywords: Clustering functions, Non-smooth Optimization, Nonconvex Optimization, Pattern Search Method.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16412625 FEA Modeling of Material Removal Rate in Electrical Discharge Machining of Al6063/SiC Composites
Authors: U. K. Vishwakarma , A. Dvivedi, P. Kumar
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Metal matrix composites (MMC) are generating extensive interest in diverse fields like defense, aerospace, electronics and automotive industries. In this present investigation, material removal rate (MRR) modeling has been carried out using an axisymmetric model of Al-SiC composite during electrical discharge machining (EDM). A FEA model of single spark EDM was developed to calculate the temperature distribution.Further, single spark model was extended to simulate the second discharge. For multi-discharge machining material removal was calculated by calculating the number of pulses. Validation of model has been done by comparing the experimental results obtained under the same process parameters with the analytical results. A good agreement was found between the experimental results and the theoretical value.Keywords: Electrical Discharge Machining, FEA, Metal matrix composites, Multi-discharge
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 37332624 Pervasiveness of Aflatoxin in Peanuts Growing in the Area of Pothohar, Pakistan
Authors: Mateen Abbas, Abdul Muqeet Khan, Muhammad Rafique Asi, Javed Akhtar
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Mycotoxin (aflatoxins) contamination of peanuts is a great concern for human health. A total of 72 samples of unripe, roasted, and salty peanuts were collected randomly from Pothohar plateau of Pakistan for the assessment of aflatoxin. Samples were dried, ground and extracted by acetonitrile (84%). The filtered extracts were cleaned up by MycoSep-226 and analyzed by high performance liquid chromatography with flourescence detector. Quantification limit of Aflatoxin was 1 μg/kg and 70% Recovery was observed in spiked samples in the range 1–10 μg/kg. The screening of mycotoxins indicated that aflatoxins were present in most of the samples being detected in 82%, in concentrations from 14.25 μg/kg to 98.80 μg/kg. Optimal conditions for mycotoxin production and fungal growth are frequently found in the crop fields as well as in store houses. Human exposure of such toxin can be controlled by pointed out such awareness and implemented the regulations.Keywords: Aflatoxin, HPLC, Pakistan, Peanuts, Punjab
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22682623 Bio-Inspired Generalized Global Shape Approach for Writer Identification
Authors: Azah Kamilah Muda, Siti Mariyam Shamsuddin, Maslina Darus
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Writer identification is one of the areas in pattern recognition that attract many researchers to work in, particularly in forensic and biometric application, where the writing style can be used as biometric features for authenticating an identity. The challenging task in writer identification is the extraction of unique features, in which the individualistic of such handwriting styles can be adopted into bio-inspired generalized global shape for writer identification. In this paper, the feasibility of generalized global shape concept of complimentary binding in Artificial Immune System (AIS) for writer identification is explored. An experiment based on the proposed framework has been conducted to proof the validity and feasibility of the proposed approach for off-line writer identification.Keywords: Writer identification, generalized global shape, individualistic, pattern recognition.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12302622 Effect of Integrity of the Earthing System on the Rise of Earth Potential
Authors: N. Ullah, A. Haddad, F. Van Der Linde
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This paper investigates the effects of breaks in bonds, breaks in the earthing system and breaks in earth wire on the rise of the earth potential (EPR) in a substation and at the transmission tower bases using various models of an L6 tower. Different approaches were adopted to examine the integrity of the earthing system and the terminal towers. These effects were investigated to see the associated difference in the EPR magnitudes with respect to a healthy system at various locations. Comparisons of the computed EPR magnitudes were then made between the healthy and unhealthy system to detect any difference. The studies were conducted at power frequency for a uniform soil with different soil resistivities. It was found that full breaks in the double bond of the terminal towers increase the EPR significantly at the fault location, while they reduce EPR at the terminal tower bases. A fault on the isolated section of the grid can result in EPR values up to 8 times of those on a healthy system at higher soil resistivities, provided that the extended earthing system stays connected to the grid.Keywords: Bonding, earthing, EPR, integrity, system.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17272621 Molecular Dynamics Simulation of Liquid-Vapor Interface on the Solid Surface Using the GEAR-S Algorithm
Authors: D. Toghraie, A. R. Azimian
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In this paper, the Lennard -Jones potential is applied to molecules of liquid argon as well as its vapor and platinum as solid surface in order to perform a non-equilibrium molecular dynamics simulation to study the microscopic aspects of liquid-vapor-solid interactions. The channel is periodic in x and y directions and along z direction it is bounded by atomic walls. It was found that density of the liquids near the solid walls fluctuated greatly and that the structure was more like a solid than a liquid. This indicates that the interactions of solid and liquid molecules are very strong. The resultant surface tension, liquid density and vapor density are found to be well predicted when compared with the experimental data for argon. Liquid and vapor densities were found to depend on the cutoff radius which induces the use of P3M (particle-particle particle-mesh) method which was implemented for evaluation of force and surface tension.Keywords: Lennard-Jones Potential, Molecular DynamicsSimulation, Periodic Boundary Conditions (PBC), Non-EquilibriumMolecular Dynamics (NEMD).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20152620 Status and Management of Grape Stem Borer, Celosterna scrabrator with Soil Application of Chlorantraniliprole 0.4 gr
Authors: D. N. Kambrekar, S. B. Jagginavar, J. Aruna
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Grape stem borer, Celosterna scrabrator is an important production constraint in grapes in India. Hitherto this pest was a severe menace only on the aged and unmanaged fields but during the recent past it has also started damaging the newly established fields. In India, since Karnataka, Andra Pradesh, Tamil Nadu and Maharashtra are the major grape production states, the incidence of stem borer is also restricted and severe in these states. The grubs of the beetle bore in to the main stem and even the branches, which affect the translocation of nutrients to the areal parts of the plant. Since, the grubs bore inside the stem, the chewed material along with its excreta is discharged outside the holes and the frass is found on the ground just below the bored holes. The portion of vines above the damaged part has a sticky appearance. The leaves become pale yellow which looks like a deficiency of micronutrients. The leaves ultimately dry and drop down. The status of the incidence of the grape stem borer in different grape growing districts of Northern Karnataka was carried out during three years. In each taluka five locations were surveyed for the incidence of grape stem borer. Further, the experiment on management of stem borer was carried out in the grape gardens of Vijayapur districts under farmers field during three years. Stem borer infested plants that show live holes were selected per treatments and it was replicated three times. Live and dead holes observed during pre-treatment were closely monitored and only plants with live holes were selected and tagged. Different doses of chlorantraniliprole 0.4% GR were incorporated into the soil around the vine basins near root zone surrounded to trunk region by removing soils up to 5-10 cm with a peripheral distance of 1 to 1.5 feet from the main trunk where feeder roots are present. Irrigation was followed after application of insecticide for proper incorporation of the test chemical. The results indicated that there was sever to moderate incidence of the stem borer in all the grape growing districts of northern Karnataka. Maximum incidence was recorded in Belagavi (11 holes per vine) and minimum was in Gadag district (8.5 holes per vine). The investigations carried out to study the efficacy of chlorantraniliprole on grape stem borer for successive three years under farmers field indicated that chlorantraniliprole @ 15g/vine applied just near the active root zone of the plant followed by irrigation has successfully managed the pest. The insecticide has translocated to all the parts of the plants and thereby stopped the activity of the pest which has resulted in to better growth of the plant and higher berry yield compared to other treatments under investigation. Thus, chlorantraniliprole 0.4 GR @ 15g/vine can be effective means in managing the stem borer.
Keywords: Chlorantraniliprole, grape stem borer, Celosterna scrabrator, management.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10892619 In silico Studies on Selected Drug Targets for Combating Drug Resistance in Plasmodium falcifarum
Authors: D. Bhaskar, N. R. Wadehra, M. Gulati, A. Narula, R. Vishnu, G. Katyal
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With drug resistance becoming widespread in Plasmodium falciparum infections, the development of the alternative drugs is the desired strategy for prevention and cure of malaria. Three drug targets were selected to screen promising drug molecules from the GSK library of 13469 molecules. Using an in silico structure-based drug designing approach, the differences in binding energies of the substrate and inhibitor were exploited between target sites of parasite and human to design a drug molecule against Plasmodium. The docking studies have shown several promising molecules from GSK library with more effective binding as compared to the already known inhibitors for the drug targets. Though stronger interaction has been shown by several molecules as compared to the reference, few molecules have shown the potential as drug candidates though in vitro studies are required to validate the results. In case of thymidylate synthase-dihydrofolatereductase (TS-DHFR), three compounds have shown promise for future studies as potential drugs.
Keywords: Drug resistance, Drug targets, In silico studies, Plasmodium falciparum.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19412618 Development and Evaluation of a Nutraceutical Herbal Summer Drink
Authors: Munish Garg, Vinni Ahuja
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In the past few years, high consumption of soft drinks has attracted negative attention world-wide due to its possible adverse effects, leading the health conscious people to find alternative nutraceutical or herbal health drinks. In the present study, a nutraceutical soft drink was developed utilizing some easily available and well known traditional herbs having nutritional potential. The key ingredients were selected as bael, amla, lemon juice, ashwagandha and poppy seeds based on their household routine use in the summer with proven refreshing, cooling and energetic feeling since ages. After several trials made, the final composition of nutraceutical summer soft drink was selected as most suitable combination based on the taste, physicochemical, microbial and organoleptic point of view. The physicochemical analysis of the prepared drink found to contain optimum level of titratable acidity, total soluble solids and pH which were in accordance of the commercial recommendations. There were no bacterial colonies found in the product therefore found within limits. During the nine point’s hedonic scale sensory evaluation, the drink was strongly liked for colour, taste, flavour and texture. The formulation was found to contain flavonoids (80mg/100ml), phenolics (103mg/100ml), vitamin C (250mg/100ml) and has antioxidant potential (75.52%) apart from providing several other essential vitamins, minerals and healthy components. The developed nutraceutical drink provides an economical and feasible option for the consumers with very good taste combined with potential health benefits. The present drink is potentially capable to replace the synthetic soft drinks available in the market.
Keywords: Herbal drink, nutraceuticals, summer drink, antioxidant.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 38982617 A Fuzzy Mixed Integer Multi-Scenario Portfolio Optimization Model
Authors: M. S. Osman, A. A. Tharwat, I. A. El-Khodary, A. G. Chalabi
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In this paper, we propose a multiple objective optimization model with respect to portfolio selection problem for investors looking forward to diversify their equity investments in a number of equity markets. Based on Markowitz-s M-V model we developed a Fuzzy Mixed Integer Multi-Objective Nonlinear Programming Problem (FMIMONLP) to maximize the investors- future gains on equity markets, reach the optimal proportion of the budget to be invested in different equities. A numerical example with a comprehensive analysis on artificial data from several equity markets is presented in order to illustrate the proposed model and its solution method. The model performed well compared with the deterministic version of the model.
Keywords: Equity Markets, Future Scenarios, PortfolioSelection, Multiple Criteria Fuzzy Optimization
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19752616 A Detailed Review on Pin Fin Heat Sink
Authors: Vedulla Manoj Kumar, B. Nageswara Rao, Sk. Farooq
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Heat sinks are being considered in many advanced heat transfer applications including automotive and stationary fuel cells as well as cooling of electronic devices. However, there are innumerable fundamental issues in the fields of heat transfer and fluid mechanics perspectives which remains unresolved. The present review emphasizes on the progress of research in the field of pin fin heat sinks, while understanding the fluid dynamics and heat transfer characteristics with a detailed and sophisticated prediction of the temperature distribution, high heat flux removal and by minimizing thermal resistance. Lot of research work carried out across the globe to address this challenge and trying to come up with an economically viable and user friendly solution. The high activities for future pin fin heat sinks research and development to meet the current issue is recorded in this article.
Keywords: Heat sinks, heat transfer, heat flux, thermal resistance, electronic devices.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 26572615 The Effect of Porous Alkali Activated Material Composition on Buffer Capacity in Bioreactors
Authors: G. Bumanis, D. Bajare
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With demand for primary energy continuously growing, search for renewable and efficient energy sources has been high on agenda of our society. One of the most promising energy sources is biogas technology. Residues coming from dairy industry and milk processing could be used in biogas production; however, low efficiency and high cost impede wide application of such technology. One of the main problems is management and conversion of organic residues through the anaerobic digestion process which is characterized by acidic environment due to the low whey pH (<6) whereas additional pH control system is required. Low buffering capacity of whey is responsible for the rapid acidification in biological treatments; therefore alkali activated material is a promising solution of this problem. Alkali activated material is formed using SiO2 and Al2O3 rich materials under highly alkaline solution. After material structure forming process is completed, free alkalis remain in the structure of materials which are available for leaching and could provide buffer capacity potential. In this research porous alkali activated material was investigated. Highly porous material structure ensures gradual leaching of alkalis during time which is important in biogas digestion process. Research of mixture composition and SiO2/Na2O and SiO2/Al2O ratio was studied to test the buffer capacity potential of alkali activated material. This research has proved that by changing molar ratio of components it is possible to obtain a material with different buffer capacity, and this novel material was seen to have considerable potential for using it in processes where buffer capacity and pH control is vitally important.
Keywords: Alkaline material, buffer capacity, biogas production.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20582614 A Study on Multi-Agent Behavior in a Soccer Game Domain
Authors: S. R. Mohd Shukri, M. K. Mohd Shaukhi
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There have been many games developing simulation of soccer games. Many of these games have been designed with highly realistic features to attract more users. Many have also incorporated better artificial intelligent (AI) similar to that in a real soccer game. One of the challenging issues in a soccer game is the cooperation, coordination and negotiation among distributed agents in a multi-agent system. This paper focuses on the incorporation of multi-agent technique in a soccer game domain. The better the cooperation of a multi-agent team, the more intelligent the game will be. Thus, past studies were done on the robotic soccer game because of the better multi-agent system implementation. From this study, a better approach and technique of multi-agent behavior could be select to improve the author-s 2D online soccer game.Keywords: Multi-Agent, Robotic Intelligent, Role Assignment, Formation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19402613 Work and Religion: Artificial Dichotomy or Competing Interests?
Authors: Philip T. Roundy
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Prior research has examined the relationship between religiosity, religious involvement, and involvement in secular, civic organizations. However, research has not examined the influence of religious involvement on secular, non-civic organizations (i.e. work organizations). This study examines the link between religiosity, religious involvement, and the three-component model of organizational commitment. More specifically, the author hypothesizes that individuals high in religiosity (and religious involvement) will have lower affective, continuance, and normative commitment than less religious (or non-religious) individuals. In addition, it is hypothesized that this relationship is moderated by a third factor: organizational spirituality. Further, the author hypothesizes that for organizations that are spiritual the negative relationship between religiosity and job commitment will be weakened or even negated.Keywords: Job Commitment, Organizational Spirituality, Religiosity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18252612 On a Pitch Duration Technique for Prosody Control
Authors: JongKuk Kim, HernSoo Hahn, Uei-Joong Yoo, MyungJin Bae
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In this paper, we propose a method of alter duration in frequency domain that control prosody in real time after pitch alteration. If there has a method to alteration duration freely among prosody information, that may used in several fields such as speech impediment person's pronunciation proof reading or language study. The pitch alteration method used control prosody altered by PSOLA synthesis method which is in time domain processing method. However, the duration of pitch alteration speech is changed by the frequency domain. In this paper, we altered the duration with the method of duration alteration by Fast Fourier Transformation in frequency domain. Consequently, the intelligibility of the pitch and duration are controlled has a slight decrease than the case when only pitch is changed, but the proposed algorithm obtained the higher MOS score about naturalness.Keywords: PSOLA, Pitch Alteration, Duration Control.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16852611 Application of Acidithiobacillus ferrooxidans in Desulfurization of US Coal: 10 L Batch Stirred Reactor Study
Authors: Ashish Pathak, Dong-Jin Kim, S. Singh, H. Srichandan, Byoung-Gon Kim
Abstract:
The desulfurization of coal using biological methods is an emerging technology. The biodesulfurization process uses the catalytic activity of chemolithotrophic acidpohiles in removing sulfur and pyrite from the coal. The present study was undertaken to examine the potential of Acidithiobacillus ferrooxidans in removing the pyritic sulfur and iron from high iron and sulfur containing US coal. The experiment was undertaken in 10 L batch stirred tank reactor having 10% pulp density of coal. The reactor was operated under mesophilic conditions and aerobic conditions were maintained by sparging the air into the reactor. After 35 days of experiment, about 64% of pyrite and 21% of pyritic sulfur was removed from the coal. The findings of the present study indicate that the biodesulfurization process does have potential in treating the high pyrite and sulfur containing coal. A good mass balance was also obtained with net loss of about 5% showing its feasibility for large scale application.
Keywords: At.ferrroxidans, Batch reactor, Coal desulfurization, Pyrite.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16692610 Solvent Effect on Antioxidant Activity and Total Phenolic Content of Betula alba and Convolvulus arvensi
Authors: Mohd Azman A. Nurul, Husni Shafik, Almajano P. Maria, Gallego G. Maria
Abstract:
The potential of using herbal Betula alba (BA) and Convolvulus arvensis (CA) as a natural antioxidant for food applications were investigated. Each plant extract was prepared by using pure ethanol, different concentration of ethanol aqueous solutions, including 50% and 75%, 50% methanol aqueous and water. Total phenolic content (TPC) was determined using Folin–Ciocalteau method and antioxidant activity were analyzed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, trolox equivalent antioxidant capacity (TEAC), Oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) respectively. Ethanol extract of CA exhibited the highest TPC and antioxidant activity; however BA showed varies of antioxidant activity value in each assay. The BA and CA exhibit the potential sources of natural antioxidant for food commodities.
Keywords: Solvent effect, Antioxidant activity, Betula Alba, Convolvulus arvensis, Total Phenolic Content.
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