Search results for: Matrix cooling
667 Semi-Blind Two-Dimensional Code Acquisition in CDMA Communications
Authors: Rui Wu, Tapani Ristaniemi
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In this paper, we propose a new algorithm for joint time-delay and direction-of-arrival (DOA) estimation, here called two-dimensional code acquisition, in an asynchronous directsequence code-division multiple-access (DS-CDMA) array system. This algorithm depends on eigenvector-eigenvalue decomposition of sample correlation matrix, and requires to know desired user-s training sequence. The performance of the algorithm is analyzed both analytically and numerically in uncorrelated and coherent multipath environment. Numerical examples show that the algorithm is robust with unknown number of coherent signals.
Keywords: Two-Dimensional Code Acquisition, EV-t, DSCDMA
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1511666 Prediction-Based Midterm Operation Planning for Energy Management of Exhibition Hall
Authors: Doseong Eom, Jeongmin Kim, Kwang Ryel Ryu
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Large exhibition halls require a lot of energy to maintain comfortable atmosphere for the visitors viewing inside. One way of reducing the energy cost is to have thermal energy storage systems installed so that the thermal energy can be stored in the middle of night when the energy price is low and then used later when the price is high. To minimize the overall energy cost, however, we should be able to decide how much energy to save during which time period exactly. If we can foresee future energy load and the corresponding cost, we will be able to make such decisions reasonably. In this paper, we use machine learning technique to obtain models for predicting weather conditions and the number of visitors on hourly basis for the next day. Based on the energy load thus predicted, we build a cost-optimal daily operation plan for the thermal energy storage systems and cooling and heating facilities through simulation-based optimization.
Keywords: Building energy management, machine learning, simulation-based optimization, operation planning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 975665 Solar Architecture of Low-Energy Buildings for Industrial Applications
Authors: P. Brinks, O. Kornadt, R. Oly
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This research focuses on the optimization of glazed surfaces and the assessment of possible solar gains in industrial buildings. Existing window rating methods for single windows were evaluated and a new method for a simple analysis of energy gains and losses by single windows was introduced. Furthermore extensive transient building simulations were carried out to appraise the performance of low cost polycarbonate multi-cell sheets in interaction with typical buildings for industrial applications. Mainly energy saving potential was determined by optimizing the orientation and area of such glazing systems in dependency on their thermal qualities. Moreover the impact on critical aspects such as summer overheating and daylight illumination was considered to ensure the user comfort and avoid additional energy demand for lighting or cooling. Hereby the simulated heating demand could be reduced by up to 1/3 compared to traditional architecture of industrial halls using mainly skylights.
Keywords: Solar Architecture, Passive Solar Building Design, Glazing, Low-Energy Buildings, Industrial Buildings.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1962664 Adaptive MPC Using a Recursive Learning Technique
Authors: Ahmed Abbas Helmy, M. R. M. Rizk, Mohamed El-Sayed
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A model predictive controller based on recursive learning is proposed. In this SISO adaptive controller, a model is automatically updated using simple recursive equations. The identified models are then stored in the memory to be re-used in the future. The decision for model update is taken based on a new control performance index. The new controller allows the use of simple linear model predictive controllers in the control of nonlinear time varying processes.
Keywords: Adaptive control, model predictive control, dynamic matrix control, online model identification
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1763663 School Design and Energy Efficiency
Authors: B. Su
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Auckland has a temperate climate with comfortable warm, dry summers and mild, wet winters. An Auckland school normally does not need air conditioning for cooling during the summer and only need heating during the winter. The space hating energy is the major portion of winter school energy consumption and the winter energy consumption is major portion of annual school energy consumption. School building thermal design should focus on the winter thermal performance for reducing the space heating energy. A number of Auckland schools- design data and energy consumption data are used for this study. This pilot study investigates the relationships between their energy consumption data and school building design data to improve future school design for energy efficiency.Keywords: Building energy efficiency, building thermal performance, school building design, school energy consumption
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1866662 Examining of Tool Wear in Cryogenic Machining of Cobalt-Based Haynes 25 Superalloy
Authors: Murat Sarıkaya, Abdulkadir Güllü
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Haynes 25 alloy (also known as L-605 alloy) is cobalt based super alloy which has widely applications such as aerospace industry, turbine and furnace parts, power generators and heat exchangers and petroleum refining components due to its excellent characteristics. However, the workability of this alloy is more difficult compared to normal steels or even stainless. In present work, an experimental investigation was performed under cryogenic cooling to determine cutting tool wear patterns and obtain optimal cutting parameters in turning of cobalt based superalloy Haynes 25. In experiments, uncoated carbide tool was used and cutting speed (V) and feed rate (f) were considered as test parameters. Tool wear (VBmax) were measured for process performance indicators. Analysis of variance (ANOVA) was performed to determine the importance of machining parameters.Keywords: Cryogenic machining, difficult-to-cut alloy, tool wear, turning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2749661 Controlled Synchronization of an Array of Nonlinear System with Time Delays
Authors: S.M. Lee, J.H. Koo, J.H. Park, S.C. Won
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In this paper, we propose synchronization of an array of nonlinear systems with time delays. The array of systems is decomposed into isolated systems to establish appropriate Lyapunov¬Krasovskii functional. Using the Lyapunov-Krasovskii functional, a sufficient condition for the synchronization is derived in terms of LMIs(Linear Matrix Inequalities). Delayed feedback control gains are obtained by solving the sufficient condition. Numerical examples are given to show the validity the proposed method.
Keywords: Synchronization, Delay, Lyapunov method, LMI.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1427660 Modeling and Performance Evaluation of Three Power Generation and Refrigeration Energy Recovery Systems from Thermal Loss of a Diesel Engine in Different Driving Conditions
Authors: H. Golchoobian, M. H. Taheri, S. Saedodin, A. Sarafraz
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This paper investigates the possibility of using three systems of organic Rankine auxiliary power generation, ejector refrigeration and absorption to recover energy from a diesel car. The analysis is done for both urban and suburban driving modes that vary from 60 to 120 km/h. Various refrigerants have also been used for organic Rankine and Ejector refrigeration cycles. The capacity was evaluated by Organic Rankine Cycle (ORC) system in both urban and suburban conditions for cyclopentane and ammonia as refrigerants. Also, for these two driving plans, produced cooling by absorption refrigeration system under variable ambient temperature conditions and in ejector refrigeration system for R123, R134a and R141b refrigerants were investigated.
Keywords: Absorption system, diesel engine, ejector refrigeration, energy recovery, organic Rankine cycle.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 682659 Proposal of Solidification/Stabilisation Process of Chosen Hazardous Waste by Cementation
Authors: Bozena Dohnalkova
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This paper presents a part of the project solving which is dedicated to the identification of the hazardous waste with the most critical production within the Czech Republic with the aim to study and find the optimal composition of the cement matrix that will ensure maximum content disposal of chosen hazardous waste. In the first stage of project solving – which represents this paper – a specific hazardous waste was chosen, its properties were identified and suitable solidification agents were chosen. Consequently solidification formulas and testing methodology was proposed.
Keywords: Cementation, solidification, waste, binder.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1859658 Existence and Exponential Stability of Almost Periodic Solution for Cohen-Grossberg SICNNs with Impulses
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In this paper, based on the estimation of the Cauchy matrix of linear impulsive differential equations, by using Banach fixed point theorem and Gronwall-Bellman-s inequality, some sufficient conditions are obtained for the existence and exponential stability of almost periodic solution for Cohen-Grossberg shunting inhibitory cellular neural networks (SICNNs) with continuously distributed delays and impulses. An example is given to illustrate the main results.
Keywords: Almost periodic solution, exponential stability, neural networks, impulses.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14320657 Performance Assessment of Carbon Nano Tube Based Cutting Fluid in Machining Process
Authors: Alluru Gopala Krishna, Thella Babu Rao
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In machining, there is always a problem with heat generation and friction produced during the process as they consequently affect tool wear and surface finish. An instant heat transfer mechanism could protect the cutting tool edge and enhance the tool life by cooling the cutting edge of the tool. In the present work, carbon nanotube (CNT) based nano-cutting fluid is proposed for machining a hard-to-cut material. Tool wear and surface roughness are considered for the evaluation of the nano-cutting fluid in turning process. The performance of nanocoolant is assessed against the conventional coolant and dry machining conditions and it is observed that the proposed nanocoolant has produced better performance than the conventional coolant.Keywords: CNT based nanocoolant, turning, tool wear, surface roughness.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1717656 Preconditioned Jacobi Method for Fuzzy Linear Systems
Authors: Lina Yan, Shiheng Wang, Ke Wang
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A preconditioned Jacobi (PJ) method is provided for solving fuzzy linear systems whose coefficient matrices are crisp Mmatrices and the right-hand side columns are arbitrary fuzzy number vectors. The iterative algorithm is given for the preconditioned Jacobi method. The convergence is analyzed with convergence theorems. Numerical examples are given to illustrate the procedure and show the effectiveness and efficiency of the method.
Keywords: preconditioning, M-matrix, Jacobi method, fuzzy linear system (FLS).
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1891655 Characterization of Indoor Power Lines as Data Communication Channels Experimental Details and Results
Authors: Sheroz Khan, A. F. Salami, W. A. Lawal, AHM Zahirul Alam, Shihab Abdel Hameed, M. J. E.Salami
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In this paper, a multi-branch power line is modeled using ABCD matrix to show its worth as a communication channel. The model is simulated using MATLAB in an effort to investigate the effects of multiple loading, multipath, and those as a result of load mismatching. The channel transfer function is obtained and investigated using different cable lengths, and different number of bridge taps under given loading conditions.
Keywords: Power line Communication, Transfer Function, Channel Modeling, Signal Transmission.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1922654 Disinfestation of Wheat Using Liquid Nitrogen Aeration
Authors: Haiyan. Li, Jitendra. Paliwal, Digvir S. Jayas, Noel D. G. White
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A study was undertaken to investigate the effect of liquid nitrogen aeration on mortalities of adult Cryptolestes furrugineus, rusty grain beetles, in a prototype cardboard grain bin equipped with an aeration system. The grain bin was filled with Hard Red Spring wheat and liquid nitrogen was introduced from the bottom of the bin. The survival of both cold acclimated and unacclimated C. furrugineus was tested. The study reveals that cold acclimated insects had higher survival than unacclimated insects under similar cooling conditions. In most cases, mortalities of as high as 100% were achieved at the bottom 100 cm of the grain bin for unacclimated insects for most of the trials. Insect survival increased as the distance from the bottom of the grain bin increased. There was no adverse effect of liquid nitrogen aeration on wheat germination.Keywords: Cold acclimated, liquid nitrogen aeration, mortalities, rusty grain beetles.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1507653 Passive Ventilation System Analysis using Solar Chimney in South of Algeria
Authors: B. Belfuguais, S. Larbi
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The work presented in this study is related to an energy system analysis based on passive cooling system for dwellings. It consists to solar chimney energy performances determination versus geometrical and environmental considerations as the size and inlet width conditions of the chimney. Adrar site located in the southern region of Algeria is chosen for this study according to ambient temperature and solar irradiance technical data availability. Obtained results are related to the glazing temperature distributions, the chimney air flow and internal wall temperatures. The air room change per hour (ACH) parameter, the outlet air velocity and mass air flow rate are also determined. It is shown that the chimney width has a significant effect on energy performances compared to its entry size. A good agreement is observed between these results and those obtained by others from the literature.Keywords: Solar chimney, Energy performances, Passive ventilation, Numerical simulation
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2915652 Influence of Differences of Heat Insulation Methods on Thermal Comfort of Apartment Buildings
Authors: Hikaru Sato, Hiroatsu Fukuda, Yupeng Wang
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The aim of this study is to analyze influence of differences of heat insulation methods on indoor thermal environment and comfort of apartment buildings. This study analyzes indoor thermal environment and comfort on units of apartment buildings using calculation software "THERB" and compares three different kinds of heat insulation methods. Those are outside insulation on outside walls, inside insulation on outside walls and interior insulation. In terms of indoor thermal environment, outside insulation is the best to stabilize room temperature. In winter, room temperature on outside insulation after heating is higher than other and it is kept 3-5 degrees higher through all night. But the surface temperature with outside insulation did not dramatically increase when heating was used, which was 3 to 5oC lower than the temperature with other insulation. The PMV of interior insulation fall nearly range of comfort when the heating and cooling was use.Keywords: Apartment Building, Indoor Thermal Environment, Insulation, PMV
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1344651 Evaluation of Corrosion by Impedance Spectroscopy of Embedded Steel in an Alternative Concrete Exposed to the Chloride Ion
Authors: Erika J. Ruíz, Jairo R. Cortes, Willian A. Aperador
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In this article was evaluated the protective effect of the alternative concrete obtained from the binary mixture of fly ash, and iron and steel slag. After mixing the cement with aggregates, structural steel was inserted in the matrix cementitious. The study was conducted comparatively with specimens exposed to natural conditions free of chloride ion. The chloride ion effect on the specimens accelerated under controlled conditions (3.5% NaCl and 25°C temperature). The impedance data were acquired in a range of 1 mHz to 100 kHz.
Keywords: Alternative concrete, corrosion, alkaline activation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1407650 New Technologies for Modeling of Gas Turbine Cooled Blades
Authors: A. Pashayev, D. Askerov, R.Sadiqov, A. Samedov, C. Ardil
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In contrast to existing methods which do not take into account multiconnectivity in a broad sense of this term, we develop mathematical models and highly effective combination (BIEM and FDM) numerical methods of calculation of stationary and cvazistationary temperature field of a profile part of a blade with convective cooling (from the point of view of realization on PC). The theoretical substantiation of these methods is proved by appropriate theorems. For it, converging quadrature processes have been developed and the estimations of errors in the terms of A.Ziqmound continuity modules have been received. For visualization of profiles are used: the method of the least squares with automatic conjecture, device spline, smooth replenishment and neural nets. Boundary conditions of heat exchange are determined from the solution of the corresponding integral equations and empirical relationships. The reliability of designed methods is proved by calculation and experimental investigations heat and hydraulic characteristics of the gas turbine 1st stage nozzle blade
Keywords: multiconnected systems, method of the boundary integrated equations, splines, neural networks.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1641649 Numerical Modeling of Gas Turbine Engines
Authors: A. Pashayev, D. Askerov, C. Ardil, R. Sadiqov
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In contrast to existing methods which do not take into account multiconnectivity in a broad sense of this term, we develop mathematical models and highly effective combination (BIEM and FDM) numerical methods of calculation of stationary and quasi-stationary temperature field of a profile part of a blade with convective cooling (from the point of view of realization on PC). The theoretical substantiation of these methods is proved by appropriate theorems. For it, converging quadrature processes have been developed and the estimations of errors in the terms of A.Ziqmound continuity modules have been received. For visualization of profiles are used: the method of the least squares with automatic conjecture, device spline, smooth replenishment and neural nets. Boundary conditions of heat exchange are determined from the solution of the corresponding integral equations and empirical relationships. The reliability of designed methods is proved by calculation and experimental investigations heat and hydraulic characteristics of the gas turbine first stage nozzle blade.
Keywords: Multiconnected systems, method of the boundary integrated equations, splines, neural networks.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1614648 Weighted Harmonic Arnoldi Method for Large Interior Eigenproblems
Authors: Zhengsheng Wang, Jing Qi, Chuntao Liu, Yuanjun Li
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The harmonic Arnoldi method can be used to find interior eigenpairs of large matrices. However, it has been shown that this method may converge erratically and even may fail to do so. In this paper, we present a new method for computing interior eigenpairs of large nonsymmetric matrices, which is called weighted harmonic Arnoldi method. The implementation of the method has been tested by numerical examples, the results show that the method converges fast and works with high accuracy.
Keywords: Harmonic Arnoldi method, weighted harmonic Arnoldi method, eigenpair, interior eigenproblem, non symmetric matrix.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1535647 Enhancing Thermal Efficiency of Double Skin Façade Buildings in Semi-Arid Climate
Authors: Farid Vahedi
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There is a great deal of interest in constructing Double Skin Facade (DSF) structures which are considered as modern movement in field of Energy Conservation, renewable energies, and Architecture design. This trend provides many conclusive alternatives which are frequently associated with sustainable building. In this paper a building with Double Skin Facade is considered in the semiarid climate of Tehran, Iran, in order to consider the DSF-s performance during hot seasons. Mathematical formulations calculate solar heat gain by the external skin. Moreover, Computational Fluid Dynamics (CFD) simulations were performed on the case study building to enhance effectiveness of the facade. The conclusion divulged difference of gained energy by the cavity and room with and without blind and louvers. Some solutions were introduced to surge the performance of natural ventilation by plunging the cooling loads in summer.
Keywords: Double Skin Façade Buildings, Energy Conservation, Renewable Energy, Natural Ventilation, Semi-arid Climate.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5411646 Mathematical Modeling of the Influence of Hydrothermal Processes in the Water Reservoir
Authors: Alibek Issakhov
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In this paper presents the mathematical model of hydrothermal processes in thermal power plant with different wind direction scenarios in the water reservoir, which is solved by the Navier - Stokes and temperature equations for an incompressible fluid in a stratified medium. Numerical algorithm based on the method of splitting by physical parameters. Three dimensional Poisson equation is solved with Fourier method by combination of tridiagonal matrix method (Thomas algorithm).Keywords: thermal power plant, hydrothermal process, large eddy simulation, water reservoir
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1632645 Affine Projection Algorithm with Variable Data-Reuse Factor
Authors: ChangWoo Lee, Young Kow Lee, Sung Jun Ban, SungHoo Choi, Sang Woo Kim
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This paper suggests a new Affine Projection (AP) algorithm with variable data-reuse factor using the condition number as a decision factor. To reduce computational burden, we adopt a recently reported technique which estimates the condition number of an input data matrix. Several simulations show that the new algorithm has better performance than that of the conventional AP algorithm.
Keywords: Affine projection algorithm, variable data-reuse factor, condition number, convergence rate, misalignment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1532644 A Reproduction of Boundary Conditions in Three-Dimensional Continuous Casting Problem
Authors: Iwona Nowak, Jacek Smolka, Andrzej J. Nowak
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The paper discusses a 3D numerical solution of the inverse boundary problem for a continuous casting process of alloy. The main goal of the analysis presented within the paper was to estimate heat fluxes along the external surface of the ingot. The verified information on these fluxes was crucial for a good design of a mould, effective cooling system and generally the whole caster. In the study an enthalpy-porosity technique implemented in Fluent package was used for modeling the solidification process. In this method, the phase change interface was determined on the basis of the liquid fraction approach. In inverse procedure the sensitivity analysis was applied for retrieving boundary conditions. A comparison of the measured and retrieved values showed a high accuracy of the computations. Additionally, the influence of the accuracy of measurements on the estimated heat fluxes was also investigated.
Keywords: Boundary inverse problem, sensitivity analysis, continuous casting, numerical simulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1510643 Air flow and Heat Transfer Modeling of an Axial Flux Permanent Magnet Generator
Authors: Airoldi G., Bumby J. R., Dominy C., G.L. Ingram, Lim C. H., Mahkamov K., N. L. Brown, A. Mebarki, M. Shanel
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Axial Flux Permanent Magnet (AFPM) Machines require effective cooling due to their high power density. The detrimental effects of overheating such as degradation of the insulation materials, magnets demagnetization, and increase of Joule losses are well known. This paper describes the CFD simulations performed on a test rig model of an air cooled Axial Flux Permanent Magnet (AFPM) generator built at Durham University to identify the temperatures and heat transfer coefficient on the stator. The Reynolds Averaged Navier-Stokes and the Energy equations are solved and the flow pattern and heat transfer developing inside the machine are described. The Nusselt number on the stator surfaces has been found. The dependency of the heat transfer on the flow field is described temperature field obtained. Tests on an experimental are undergoing in order to validate the CFD results.
Keywords: Axial flux permanent magnet machines, thermal modeling, CFD.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2298642 Using Fly Ash as a Reinforcement to Increase Wear Resistance of Pure Magnesium
Authors: E. Karakulak, R. Yamanoğlu, M. Zeren
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In the current study, fly ash obtained from a thermal power plant was used as reinforcement in pure magnesium. The composite materials with different fly ash contents were produced with powder metallurgical methods. Powder mixtures were sintered at 540oC under 30 MPa pressure for 15 minutes in a vacuum assisted hot press. Results showed that increasing ash content continuously increases hardness of the composite. On the other hand, minimum wear damage was obtained at 2 wt. % ash content. Addition of higher level of fly ash results with formation of cracks in the matrix and increases wear damage of the material.Keywords: Mg composite, fly ash, wear, powder metallurgy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1378641 Delay-Dependent Stability Analysis for Neural Networks with Distributed Delays
Authors: Qingqing Wang, Shouming Zhong
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This paper deals with the problem of delay-dependent stability for neural networks with distributed delays. Some new sufficient condition are derived by constructing a novel Lyapunov-Krasovskii functional approach. The criteria are formulated in terms of a set of linear matrix inequalities, this is convenient for numerically checking the system stability using the powerful MATLAB LMI Toolbox. Moreover, in order to show the stability condition in this paper gives much less conservative results than those in the literature, numerical examples are considered.
Keywords: Neural networks, Globally asymptotic stability , LMI approach, Distributed delays.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1558640 Solving the Nonlinear Heat Conduction in a Spherical Coordinate with Electrical Simulation
Authors: A. M. Gheitaghy, H. Saffari, G. Q. Zhang
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Numerical approach based on the electrical simulation method is proposed to solve a nonlinear transient heat conduction problem with nonlinear boundary for a spherical body. This problem represents a strong nonlinearity in both the governing equation for temperature dependent thermal property and the boundary condition for combined convective and radiative cooling. By analysing the equivalent electrical model using the electrical circuit simulation program HSPICE, transient temperature and heat flux distributions at sphere can be obtained easily and fast. The solutions clearly illustrate the effect of the radiation-conduction parameter Nrc, the Biot number and the linear coefficient of temperature dependent conductivity and heat capacity. On comparing the results with corresponding numerical solutions, the accuracy and efficiency of this computational method is found to be good.Keywords: Convective boundary, radiative boundary, electrical simulation method, nonlinear heat conduction, spherical coordinate.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1375639 Formulation and in vitro Evaluation of Ondansetron Hydrochloride Matrix Transdermal Systems Using Ethyl Cellulose/Polyvinyl Pyrrolidone Polymer Blends
Authors: Rajan Rajabalaya, Li-Qun Tor, Sheba David
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Transdermal delivery of ondansetron hydrochloride (OdHCl) can prevent the problems encountered with oral ondansetron. In previously conducted studies, effect of amount of polyvinyl pyrrolidone, permeation enhancer and casting solvent on the physicochemical properties on OdHCl were investigated. It is feasible to develop ondansetron transdermal patch by using ethyl cellulose and polyvinyl pyrrolidone with dibutyl pthalate as plasticizer, however, the desired flux is not achieved. The primary aim of this study is to use dimethyl succinate (DMS) and propylene glycol that are not incorporated in previous studies to determine their effect on the physicochemical properties of an OdHCl transdermal patch using ethyl cellulose and polyvinyl pyrrolidone. This study also investigates the effect of permeation enhancer (eugenol and phosphatidylcholine) on the release of OdHCl. The results showed that propylene glycol is a more suitable plasticizer compared to DMS in the fabrication of OdHCl transdermal patch using ethyl cellulose and polyvinyl pyrrolidone as polymers. Propylene glycol containing patch has optimum drug content, thickness, moisture content and water absorption, tensile strength, and a better release profile than DMS. Eugenol and phosphatidylcholine can increase release of OdHCl from the patches. From the physicochemical result and permeation profile, a combination of 350mg of ethyl cellulose, 150mg polyvinyl pyrrolidone, 3% of total polymer weight of eugenol, and 40% of total polymer weight of propylene glycol is the most suitable formulation to develop an OdHCl patch. OdHCl release did not increase with increasing the percentage of plasticiser. DMS 4, PG 4, DMS 9, PG 9, DMS 14, and PG 14 gave better release profiles where using 300mg: 0mg, 300mg: 100mg, and 350mg: 150mg of EC: PVP. Thus, 40% of PG or DMS appeared to be the optimum amount of plasticiser when the above combination where EC: PVP was used. It was concluded from the study that a patch formulation containing 350mg EC, 150mg PVP, 40% PG and 3% eugenol is the best transdermal matrix patch compositions for the uniform and continuous release/permeation of OdHCl over an extended period. This patch design can be used for further pharmacokinetic and pharmacodynamic studies in suitable animal models.
Keywords: Ondansetron hydrochloride, dimethyl succinate, eugenol.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2448638 Robust BIBO Stabilization Analysis for Discrete-time Uncertain System
Authors: Zixin Liu, Shu Lü, Shouming Zhong, Mao Ye
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The discrete-time uncertain system with time delay is investigated for bounded input bounded output (BIBO). By constructing an augmented Lyapunov function, three different sufficient conditions are established for BIBO stabilization. These conditions are expressed in the form of linear matrix inequalities (LMIs), whose feasibility can be easily checked by using Matlab LMI Toolbox. Two numerical examples are provided to demonstrate the effectiveness of the derived results.
Keywords: Robust BIBO stabilization, delay-dependent stabilization, discrete-time system, time delay.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1576