Search results for: Structural identification
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 2127

Search results for: Structural identification

1437 Automated Method Time Measurement System for Redesigning Dynamic Facility Layout

Authors: Salam Alzubaidi, G. Fantoni, F. Failli, M. Frosolini

Abstract:

The dynamic facility layout problem is a really critical issue in the competitive industrial market; thus, solving this problem requires robust design and effective simulation systems. The sustainable simulation requires inputting reliable and accurate data into the system. So this paper describes an automated system integrated into the real environment to measure the duration of the material handling operations, collect the data in real-time, and determine the variances between the actual and estimated time schedule of the operations in order to update the simulation software and redesign the facility layout periodically. The automated method- time measurement system collects the real data through using Radio Frequency-Identification (RFID) and Internet of Things (IoT) technologies. Hence, attaching RFID- antenna reader and RFID tags enables the system to identify the location of the objects and gathering the time data. The real duration gathered will be manipulated by calculating the moving average duration of the material handling operations, choosing the shortest material handling path, and then updating the simulation software to redesign the facility layout accommodating with the shortest/real operation schedule. The periodic simulation in real-time is more sustainable and reliable than the simulation system relying on an analysis of historical data. The case study of this methodology is in cooperation with a workshop team for producing mechanical parts. Although there are some technical limitations, this methodology is promising, and it can be significantly useful in the redesigning of the manufacturing layout.

Keywords: Dynamic facility layout problem, internet of things, method time measurement, radio frequency identification, simulation.

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1436 Identification of Promiscuous Epitopes for Cellular Immune Responses in the Major Antigenic Protein Rv3873 Encoded by Region of Difference 1 of Mycobacterium tuberculosis

Authors: Abu Salim Mustafa

Abstract:

Rv3873 is a relatively large size protein (371 amino acids in length) and its gene is located in the immunodominant genomic region of difference (RD)1 that is present in the genome of Mycobacterium tuberculosis but deleted from the genomes of all the vaccine strains of Bacillus Calmette Guerin (BCG) and most other mycobacteria. However, when tested for cellular immune responses using peripheral blood mononuclear cells from tuberculosis patients and BCG-vaccinated healthy subjects, this protein was found to be a major stimulator of cell mediated immune responses in both groups of subjects. In order to further identify the sequence of immunodominant epitopes and explore their Human Leukocyte Antigen (HLA)-restriction for epitope recognition, 24 peptides (25-mers overlapping with the neighboring peptides by 10 residues) covering the sequence of Rv3873 were synthesized chemically using fluorenylmethyloxycarbonyl chemistry and tested in cell mediated immune responses. The results of these experiments helped in the identification of an immunodominant peptide P9 that was recognized by people expressing varying HLA-DR types. Furthermore, it was also predicted to be a promiscuous binder with multiple epitopes for binding to HLA-DR, HLA-DP and HLA-DQ alleles of HLA-class II molecules that present antigens to T helper cells, and to HLA-class I molecules that present antigens to T cytotoxic cells. In addition, the evaluation of peptide P9 using an immunogenicity predictor server yielded a high score (0.94), which indicated a greater probability of this peptide to elicit a protective cellular immune response. In conclusion, P9, a peptide with multiple epitopes and ability to bind several HLA class I and class II molecules for presentation to cells of the cellular immune response, may be useful as a peptide-based vaccine against tuberculosis.

Keywords: Mycobacterium tuberculosis, Rv3873, peptides, vaccine

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1435 Sustainable Development of Medium Strength Concrete Using Polypropylene as Aggregate Replacement

Authors: Reza Keihani, Ali Bahadori-Jahromi, Timothy James Clacy

Abstract:

Plastic as an environmental burden is a well-rehearsed topic in the research area. This is due to its global demand and destructive impacts on the environment, which has been a significant concern to the governments. Typically, the use of plastic in the construction industry is seen across low-density, non-structural applications due to its diverse range of benefits including high strength-to-weight ratios, manipulability and durability. It can be said that with the level of plastic consumption experienced in the construction industry, an ongoing responsibility is shown for this sector to continually innovate alternatives for application of recycled plastic waste such as using plastic made replacement from polyethylene, polystyrene, polyvinyl and polypropylene in the concrete mix design. In this study, the impact of partially replaced fine aggregate with polypropylene in the concrete mix design was investigated to evaluate the concrete’s compressive strength by conducting an experimental work which comprises of six concrete mix batches with polypropylene replacements ranging from 0.5 to 3.0%. The results demonstrated a typical decline in the compressive strength with the addition of plastic aggregate, despite this reduction generally mitigated as the level of plastic in the concrete mix increased. Furthermore, two of the six plastic-containing concrete mixes tested in the current study exceeded the ST5 standardised prescribed concrete mix compressive strength requirement at 28-days containing 1.50% and 2.50% plastic aggregates, which demonstrated the potential for use of recycled polypropylene in structural applications, as a partial by mass, fine aggregate replacement in the concrete mix.

Keywords: Compressive strength, concrete, polypropylene, sustainability.

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1434 Structural Performance Evaluation of Electronic Road Sign Panels Reflecting Damage Scenarios

Authors: Junwon Seo, Bipin Adhikari, Euiseok Jeong

Abstract:

This paper is intended to evaluate the structural performance of welded electronic road signs under various damage scenarios (DSs) using a finite element (FE) model calibrated with full-scale ultimate load testing results. The tested electronic road sign specimen was built with a back skin made of 5052 aluminum and two channels and a frame made of 6061 aluminum, where the back skin was connected to the frame by welding. The size of the tested specimen was 1.52 m long, 1.43 m wide, and 0.28 m deep. An actuator applied vertical loads at the center of the back skin of the specimen, resulting in a displacement of 158.7 mm and an ultimate load of 153.46 kN. Using these testing data, generation and calibration of a FE model of the tested specimen were executed in ABAQUS, indicating that the difference in the ultimate load between the calibrated model simulation and full-scale testing was only 3.32%. Then, six different DSs were simulated where the areas of the welded connection in the calibrated model were diminished for the DSs. It was found that the corners at the back skin-frame joint were prone to connection failure for all the DSs, and failure of the back skin-frame connection occurred remarkably from the distant edges.

Keywords: Computational analysis, damage scenarios, electronic road signs, finite element, welded connections.

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1433 Considering the Effect of Semi-Rigid Connection in Steel Frame Structures for Progressive Collapse

Authors: Fooad Karimi Ghaleh Jough, Mohsen Soori

Abstract:

Today, the occurrence of progressive failure in structures has become a challenging issue, requiring the presentation of suitable solutions for structural resistance to this phenomenon. It is also necessary to evaluate the vulnerability of existing and under-construction buildings to progressive failure. The kind of lateral load-resisting system the building and its connections have is one of the most significant and influential variables in structural resistance to the risk of progressing failure. Using the "Alternative Path" approach suggested by the GSA2003 and UFC2013 recommendations, different configurations of semi-rigid connections against progressive failure are offered in this study. In order to do this, the Opensees program was used to model nine distinct semi-rigid connection configurations on a three-story Special Area of Conservation (SAC) structure, accounting for the impact of connection stiffness. Then, using nonlinear dynamic analysis, the effects of column removal were explored in two scenarios: corner column removal and middle column removal on the first level. Nonlinear static analysis results showed that when a column is removed, structures with semi-rigid connections experience larger displacements, which result in the construction of a plastic hinge. Furthermore, it was clear from the findings of the nonlinear static analysis that the possibility of progressive failure increased with the number of semi-rigid connections in the structure.

Keywords: Semi-rigid, nonlinear static analysis, progressive collapse, alternative path.

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1432 Structural Analysis of a Composite Wind Turbine Blade

Authors: C. Amer, M. Sahin

Abstract:

The design of an optimised horizontal axis 5-meter-long wind turbine rotor blade in according with IEC 61400-2 standard is a research and development project in order to fulfil the requirements of high efficiency of torque from wind production and to optimise the structural components to the lightest and strongest way possible. For this purpose, a research study is presented here by focusing on the structural characteristics of a composite wind turbine blade via finite element modelling and analysis tools. In this work, first, the required data regarding the general geometrical parts are gathered. Then, the airfoil geometries are created at various sections along the span of the blade by using CATIA software to obtain the two surfaces, namely; the suction and the pressure side of the blade in which there is a hat shaped fibre reinforced plastic spar beam, so-called chassis starting at 0.5m from the root of the blade and extends up to 4 m and filled with a foam core. The root part connecting the blade to the main rotor differential metallic hub having twelve hollow threaded studs is then modelled. The materials are assigned as two different types of glass fabrics, polymeric foam core material and the steel-balsa wood combination for the root connection parts. The glass fabrics are applied using hand wet lay-up lamination with epoxy resin as METYX L600E10C-0, is the unidirectional continuous fibres and METYX XL800E10F having a tri-axial architecture with fibres in the 0,+45,-45 degree orientations in a ratio of 2:1:1. Divinycell H45 is used as the polymeric foam. The finite element modelling of the blade is performed via MSC PATRAN software with various meshes created on each structural part considering shell type for all surface geometries, and lumped mass were added to simulate extra adhesive locations. For the static analysis, the boundary conditions are assigned as fixed at the root through aforementioned bolts, where for dynamic analysis both fixed-free and free-free boundary conditions are made. By also taking the mesh independency into account, MSC NASTRAN is used as a solver for both analyses. The static analysis aims the tip deflection of the blade under its own weight and the dynamic analysis comprises normal mode dynamic analysis performed in order to obtain the natural frequencies and corresponding mode shapes focusing the first five in and out-of-plane bending and the torsional modes of the blade. The analyses results of this study are then used as a benchmark prior to modal testing, where the experiments over the produced wind turbine rotor blade has approved the analytical calculations.

Keywords: Dynamic analysis, Fiber Reinforced Composites, Horizontal axis wind turbine blade, Hand-wet layup, Modal Testing.

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1431 Representation of Power System for Electromagnetic Transient Calculation

Authors: P. Sowa

Abstract:

The new idea of analyze of power system failure with use of artificial neural network is proposed. An analysis of the possibility of simulating phenomena accompanying system faults and restitution is described. It was indicated that the universal model for the simulation of phenomena in whole analyzed range does not exist. The main classic method of search of optimal structure and parameter identification are described shortly. The example with results of calculation is shown.

Keywords: Dynamic equivalents, Network reduction, Neural networks, Power system analysis.

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1430 Evolutionary Decision Trees and Software Metrics for Module Defects Identification

Authors: Monica Chiş

Abstract:

Software metric is a measure of some property of a piece of software or its specification. The aim of this paper is to present an application of evolutionary decision trees in software engineering in order to classify the software modules that have or have not one or more reported defects. For this some metrics are used for detecting the class of modules with defects or without defects.

Keywords: Evolutionary decision trees, decision trees, softwaremetrics.

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1429 Effects of Corrosion on Reinforced Concrete Beams with Silica Fume and Polypropylene Fibre

Authors: S.Shanmugam, V.G. Srisanthi, S.Ramachandran

Abstract:

Reinforced concrete has good durability and excellent structural performance. But there are cases of early deterioration due to a number of factors, one prominent factor being corrosion of steel reinforcement. The process of corrosion sets in due to ingress of moisture, oxygen and other ingredients into the body of concrete, which is unsound, permeable and absorbent. Cracks due to structural and other causes such as creep, shrinkage, etc also allow ingress of moisture and other harmful ingredients and thus accelerate the rate of corrosion. There are several interactive factors both external and internal, which lead to corrosion of reinforcement and ultimately failure of structures. Suitable addition of mineral admixture like silica fume (SF) in concrete improves the strength and durability of concrete due to considerable improvement in the microstructure of concrete composites, especially at the transition zone. Secondary reinforcement in the form of fibre is added to concrete, which provides three dimensional random reinforcement in the entire mass of concrete. Reinforced concrete beams of size 0.1 m X 0.15 m and length 1m have been cast using M 35 grade of concrete. The beams after curing process were subjected to corrosion process by impressing an external Direct Current (Galvanostatic Method) for a period of 15 days under stressed and unstressed conditions. The corroded beams were tested by applying two point loads to determine the ultimate load carrying capacity and cracking pattern and the results of specimens were compared with that of the companion specimens. Gravimetric method is used to quantify corrosion that has occurred.

Keywords: Carbonation, Corrosion, Cracking, Spalling.

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1428 Site Inspection and Evaluation Behavior of Qing Shang Concrete Bridge

Authors: Haleem K. Hussain, Liu Gui Wei, Zhang Lian Zhen, Yongxue Li

Abstract:

It is necessary to evaluate the bridges conditions and strengthen bridges or parts of them. The reinforcement necessary due to some reasons can be summarized as: First, a changing in use of bridge could produce internal forces in a part of structural which exceed the existing cross-sectional capacity. Second, bridges may also need reinforcement because damage due to external factors which reduced the cross-sectional resistance to external loads. One of other factors could listed here its misdesign in some details, like safety of bridge or part of its.This article identify the design demands of Qing Shan bridge located in is in Heilongjiang Province He gang - Nen Jiang Road 303 provincial highway, Wudalianchi area, China, is an important bridge in the urban areas. The investigation program was include the observation and evaluate the damage in T- section concrete beams , prestressed concrete box girder bridges section in additional evaluate the whole state of bridge includes the pier , abutments , bridge decks, wings , bearing and capping beam, joints, ........etc. The test results show that the bridges in general structural condition are good. T beam span No 10 were observed, crack extended upward along the ribbed T beam, and continue to the T beam flange. Crack width varying between 0.1mm to 0.4mm, the maximum about 0.4mm. The bridge needs to be improved flexural bending strength especially at for T beam section.

Keywords: Field investigation, prestressed concrete box girder, maintenance, Qing Shan Bridge

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1427 Studying the Structural Behaviour of RC Beams with Circular Openings of Different Sizes and Locations Using FE Method

Authors: Ali Shubbar, Hasanain Alwan, Ee Yu Phur, John McLoughlin, Ameer Al-khaykan

Abstract:

This paper aims to investigate the structural behaviour of RC beams with circular openings of different sizes and locations modelled using ABAQUS FEM software. Seven RC beams with the dimensions of 1200 mm×150 mm×150 mm were tested under three-point loading. Group A consists of three RC beams incorporating circular openings with diameters of 40 mm, 55 mm and 65 mm in the shear zone. However, Group B consists of three RC beams incorporating circular openings with diameters of 40 mm, 55 mm and 65 mm in the flexural zone. The final RC beam did not have any openings, to provide a control beam for comparison. The results show that increasing the diameter of the openings increases the maximum deflection and the ultimate failure load decreases relative to the control beam. In the shear zone, the presence of the openings caused an increase in the maximum deflection ranging between 4% and 22% and a decrease in the ultimate failure load of between 26% and 36% compared to the control beam. However, the presence of the openings in the flexural zone caused an increase in the maximum deflection of between 1.5% and 19.7% and a decrease in the ultimate failure load of between 6% and 13% relative to the control beam. In this study, the optimum location for placing circular openings was found to be in the flexural zone of the beam with a diameter of less than 30% of the depth of the beam.

Keywords: Ultimate failure load, maximum deflection, shear zone, flexural zone.

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1426 Sensitivity Analysis of Principal Stresses in Concrete Slab of Rigid Pavement Made From Recycled Materials

Authors: Aleš Florian, Lenka Ševelová

Abstract:

Complex sensitivity analysis of stresses in a concrete slab of the real type of rigid pavement made from recycled materials is performed. The computational model of the pavement is designed as a spatial (3D) model, is based on a nonlinear variant of the finite element method that respects the structural nonlinearity, enables to model different arrangements of joints, and the entire model can be loaded by the thermal load. Interaction of adjacent slabs in joints and contact of the slab and the subsequent layer are modeled with the help of special contact elements. Four concrete slabs separated by transverse and longitudinal joints and the additional structural layers and soil to the depth of about 3m are modeled. The thickness of individual layers, physical and mechanical properties of materials, characteristics of joints, and the temperature of the upper and lower surface of slabs are supposed to be random variables. The modern simulation technique Updated Latin Hypercube Sampling with 20 simulations is used. For sensitivity analysis the sensitivity coefficient based on the Spearman rank correlation coefficient is utilized. As a result, the estimates of influence of random variability of individual input variables on the random variability of principal stresses s1 and s3 in 53 points on the upper and lower surface of the concrete slabs are obtained.

Keywords: Concrete, FEM, pavement, sensitivity, simulation.

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1425 Electron Density Discrepancy Analysis of Energy Metabolism Coenzymes

Authors: Alan Luo, Hunter N. B. Moseley

Abstract:

Many macromolecular structure entries in the Protein Data Bank (PDB) have a range of regional (localized) quality issues, be it derived from X-ray crystallography, Nuclear Magnetic Resonance (NMR) spectroscopy, or other experimental approaches. However, most PDB entries are judged by global quality metrics like R-factor, R-free, and resolution for X-ray crystallography or backbone phi-psi distribution statistics and average restraint violations for NMR. Regional quality is often ignored when PDB entries are re-used for a variety of structurally based analyses. The binding of ligands, especially ligands involved in energy metabolism, is of particular interest in many structurally focused protein studies. Using a regional quality metric that provides chemically interpretable information from electron density maps, a significant number of outliers in regional structural quality was detected across X-ray crystallographic PDB entries for proteins bound to biochemically critical ligands. In this study, a series of analyses was performed to evaluate both specific and general potential factors that could promote these outliers. In particular, these potential factors were the minimum distance to a metal ion, the minimum distance to a crystal contact, and the isotropic atomic b-factor. To evaluate these potential factors, Fisher’s exact tests were performed, using regional quality criteria of outlier (top 1%, 2.5%, 5%, or 10%) versus non-outlier compared to a potential factor metric above versus below a certain outlier cutoff. The results revealed a consistent general effect from region-specific normalized b-factors but no specific effect from metal ion contact distances and only a very weak effect from crystal contact distance as compared to the b-factor results. These findings indicate that no single specific potential factor explains a majority of the outlier ligand-bound regions, implying that human error is likely as important as these other factors. Thus, all factors, including human error, should be considered when regions of low structural quality are detected. Also, the downstream re-use of protein structures for studying ligand-bound conformations should screen the regional quality of the binding sites. Doing so prevents misinterpretation due to the presence of structural uncertainty or flaws in regions of interest.

Keywords: Biomacromolecular structure, coenzyme, electron density discrepancy analysis, X-ray crystallography.

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1424 A Corpus-Based Study on the Styles of Three Translators

Authors: Wang Yunhong

Abstract:

The present paper is preoccupied with the different styles of three translators in their translating a Chinese classical novel Shuihu Zhuan. Based on a parallel corpus, it adopts a target-oriented approach to look into whether and what stylistic differences and shifts the three translations have revealed. The findings show that the three translators demonstrate different styles concerning their word choices and sentence preferences, which implies that identification of recurrent textual patterns may be a basic step for investigating the style of a translator.

Keywords: Corpus, lexical choices, sentence characteristics, style.

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1423 The Game of Maundy Block

Authors: Alessandro Cincotti

Abstract:

The game of Maundy Block is the three-player variant of Maundy Cake, a classical combinatorial game. Even though to determine the solution of Maundy Cake is trivial, solving Maundy Block is challenging because of the identification of queer games, i.e., games where no player has a winning strategy.

Keywords: Combinatorial game, Maundy Cake, Three-player partizan games.

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1422 Image Segmentation Using 2-D Histogram in RGB Color Space in Digital Libraries

Authors: El Asnaoui Khalid, Aksasse Brahim, Ouanan Mohammed

Abstract:

This paper presents an unsupervised color image segmentation method. It is based on a hierarchical analysis of 2-D histogram in RGB color space. This histogram minimizes storage space of images and thus facilitates the operations between them. The improved segmentation approach shows a better identification of objects in a color image and, at the same time, the system is fast.

Keywords: Image segmentation, hierarchical analysis, 2-D histogram, Classification.

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1421 Latent Factors of Severity in Truck-Involved and Non-Truck-Involved Crashes on Freeways

Authors: Shin-Hyung Cho, Dong-Kyu Kim, Seung-Young Kho

Abstract:

Truck-involved crashes have higher crash severity than non-truck-involved crashes. There have been many studies about the frequency of crashes and the development of severity models, but those studies only analyzed the relationship between observed variables. To identify why more people are injured or killed when trucks are involved in the crash, we must examine to quantify the complex causal relationship between severity of the crash and risk factors by adopting the latent factors of crashes. The aim of this study was to develop a structural equation or model based on truck-involved and non-truck-involved crashes, including five latent variables, i.e. a crash factor, environmental factor, road factor, driver’s factor, and severity factor. To clarify the unique characteristics of truck-involved crashes compared to non-truck-involved crashes, a confirmatory analysis method was used. To develop the model, we extracted crash data from 10,083 crashes on Korean freeways from 2008 through 2014. The results showed that the most significant variable affecting the severity of a crash is the crash factor, which can be expressed by the location, cause, and type of the crash. For non-truck-involved crashes, the crash and environment factors increase severity of the crash; conversely, the road and driver factors tend to reduce severity of the crash. For truck-involved crashes, the driver factor has a significant effect on severity of the crash although its effect is slightly less than the crash factor. The multiple group analysis employed to analyze the differences between the heterogeneous groups of drivers.

Keywords: Crash severity, structural equation modeling, truck-involved crashes, multiple group analysis, crash on freeway.

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1420 On Bounding Jayanti's Distributed Mutual Exclusion Algorithm

Authors: Awadhesh Kumar Singh

Abstract:

Jayanti-s algorithm is one of the best known abortable mutual exclusion algorithms. This work is an attempt to overcome an already known limitation of the algorithm while preserving its all important properties and elegance. The limitation is that the token number used to assign process identification number to new incoming processes is unbounded. We have used a suitably adapted alternative data structure, in order to completely eliminate the use of token number, in the algorithm.

Keywords: Abortable, deterministic, local spin, mutual exclusion.

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1419 Res2ValHUM: Creation of Resource Management Tool and Microbial Consortia Isolation and Identification

Authors: A. Ribeiro, N. Valério, C. Vilarinho, J. Araujo, J. Carvalho

Abstract:

Res2ValHUM project involves institutions from the Spanish Autonomous Region of Galicia and the north of Portugal (districts of Porto and Braga) and has as overall objectives of promotion of composting as an process for the correct managing of organic waste, valorization of compost in different fields or applications for the constitution of products with high added value, reducing of raw materials losses, and reduction of the amount of waste throw in landfills. Three main actions were designed to achieve the objectives: development of a management tool to improve collection and residue channeling for composting, sensibilization of the population for composting and characterization of the chemical and biological properties of compost and humic and fulvic substances to envisage high-value applications of compost. Here we present the cooperative activity of Galician and northern Portuguese institutions to valorize organic waste in both regions with common socio-economic characteristics and residue management problems. Results from the creation of the resource manage tool proved the existence of a large number of agricultural wastes that could be valorized. In the North of Portugal, the wastes from maize, oats, potato, apple, grape pomace, rye, and olive pomace can be highlighted. In the Autonomous Region of Galicia the wastes from maize, wheat, potato, apple, and chestnuts can be emphasized. Regarding the isolation and identification of microbial consortia from compost samples, results proved microorganisms belong mainly to the genus Bacillus spp. Among all the species identified in compost samples, Bacillus licheniformis can be highlighted in the production of humic and fulvic acids.

Keywords: Agricultural wastes, Bacillus licheniformis, Bacillus spp., Humic-acids, Fulvic-acids.

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1418 Stability Optimization of Functionally Graded Pipes Conveying Fluid

Authors: Karam Y. Maalawi, Hanan E.M EL-Sayed

Abstract:

This paper presents an exact analytical model for optimizing stability of thin-walled, composite, functionally graded pipes conveying fluid. The critical flow velocity at which divergence occurs is maximized for a specified total structural mass in order to ensure the economic feasibility of the attained optimum designs. The composition of the material of construction is optimized by defining the spatial distribution of volume fractions of the material constituents using piecewise variations along the pipe length. The major aim is to tailor the material distribution in the axial direction so as to avoid the occurrence of divergence instability without the penalty of increasing structural mass. Three types of boundary conditions have been examined; namely, Hinged-Hinged, Clamped- Hinged and Clamped-Clamped pipelines. The resulting optimization problem has been formulated as a nonlinear mathematical programming problem solved by invoking the MatLab optimization toolbox routines, which implement constrained function minimization routine named “fmincon" interacting with the associated eigenvalue problem routines. In fact, the proposed mathematical models have succeeded in maximizing the critical flow velocity without mass penalty and producing efficient and economic designs having enhanced stability characteristics as compared with the baseline designs.

Keywords: Functionally graded materials, pipe flow, optimumdesign, fluid- structure interaction

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1417 TNFRSF11B Gene Polymorphisms A163G and G11811C in Prediction of Osteoporosis Risk

Authors: Boroňová I., Bernasovská J., Kľoc J., Tomková Z., Petrejčíková E., Gabriková D., Mačeková S.

Abstract:

Osteoporosis is a complex health disease characterized by low bone mineral density, which is determined by an interaction of genetics with metabolic and environmental factors. Current research in genetics of osteoporosis is focused on identification of responsible genes and polymorphisms. TNFRSF11B gene plays a key role in bone remodeling. The aim of this study was to investigate the genotype and allele distribution of A163G (rs3102735) osteoprotegerin gene promoter and G1181C (rs2073618) osteoprotegerin first exon polymorphisms in the group of 180 unrelated postmenopausal women with diagnosed osteoporosis and 180 normal controls. Genomic DNA was isolated from peripheral blood leukocytes using standard methodology. Genotyping for presence of different polymorphisms was performed using the Custom Taqman®SNP Genotyping assays. Hardy-Weinberg equilibrium was tested for each SNP in the groups of participants using the chi-square (χ2) test. The distribution of investigated genotypes in the group of patients with osteoporosis were as follows: AA (66.7%), AG (32.2%), GG (1.1%) for A163G polymorphism; GG (19.4%), CG (44.4%), CC (36.1%) for G1181C polymorphism. The distribution of genotypes in normal controls were follows: AA (71.1%), AG (26.1%), GG (2.8%) for A163G polymorphism; GG (22.2%), CG (48.9%), CC (28.9%) for G1181C polymorphism. In A163G polymorphism the variant G allele was more common among patients with osteoporosis: 17.2% versus 15.8% in normal controls. Also, in G1181C polymorphism the phenomenon of more frequent occurrence of C allele in the group of patients with osteoporosis was observed (58.3% versus 53.3%). Genotype and allele distributions showed no significant differences (A163G: χ2=0.270, p=0.605; χ2=0.250, p=0.616; G1181C: χ2= 1.730, p=0.188; χ2=1.820, p=0.177). Our results represents an initial study, further studies of more numerous file and associations studies will be carried out. Knowing the distribution of genotypes is important for assessing the impact of these polymorphisms on various parameters associated with osteoporosis. Screening for identification of “at-risk” women likely to develop osteoporosis and initiating subsequent early intervention appears to be most effective strategy to substantially reduce the risks of osteoporosis.

Keywords: Osteoporosis, Real-time PCR method, SNP polymorphisms.

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1416 Seismic Retrofitting of RC Buildings with Soft Storey and Floating Columns

Authors: Vinay Agrawal, Suyash Garg, Ravindra Nagar, Vinay Chandwani

Abstract:

Open ground storey with floating columns is a typical feature in the modern multistory constructions in urban India. Such features are very much undesirable in buildings built in seismically active areas. The present study proposes a feasible solution to mitigate the effects caused due to non-uniformity of stiffness and discontinuity in load path and to simultaneously hold the functional use of the open storey particularly under the floating column, through a combination of various lateral strengthening systems. An investigation is performed on an example building with nine different analytical models to bring out the importance of recognising the presence of open ground storey and floating columns. Two separate analyses on various models of the building namely, the equivalent static analysis and the response spectrum analysis as per IS: 1893-2002 were performed. Various measures such as incorporation of Chevron bracings and shear walls, strengthening the columns in the open ground storey, and their different combinations were examined. The analysis shows that, in comparison to two short ones separated by interconnecting beams, the structural walls are most effective when placed at the periphery of the buildings and used as one long structural wall. Further, it can be shown that the force transfer from floating columns becomes less horizontal when the Chevron Bracings are placed just below them, thereby reducing the shear forces in the beams on which the floating column rests.

Keywords: Equivalent static analysis, floating column, open ground storey, response spectrum analysis, shear wall, stiffness irregularity.

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1415 Bridge Health Monitoring: A Review

Authors: Mohammad Bakhshandeh

Abstract:

Structural Health Monitoring (SHM) is a crucial and necessary practice that plays a vital role in ensuring the safety and integrity of critical structures, and in particular, bridges. The continuous monitoring of bridges for signs of damage or degradation through Bridge Health Monitoring (BHM) enables early detection of potential problems, allowing for prompt corrective action to be taken before significant damage occurs. Although all monitoring techniques aim to provide accurate and decisive information regarding the remaining useful life, safety, integrity, and serviceability of bridges, understanding the development and propagation of damage is vital for maintaining uninterrupted bridge operation. Over the years, extensive research has been conducted on BHM methods, and experts in the field have increasingly adopted new methodologies. In this article, we provide a comprehensive exploration of the various BHM approaches, including sensor-based, non-destructive testing (NDT), model-based, and artificial intelligence (AI)-based methods. We also discuss the challenges associated with BHM, including sensor placement and data acquisition, data analysis and interpretation, cost and complexity, and environmental effects, through an extensive review of relevant literature and research studies. Additionally, we examine potential solutions to these challenges and propose future research ideas to address critical gaps in BHM.

Keywords: Structural health monitoring, bridge health monitoring, sensor-based methods, machine-learning algorithms, model-based techniques, sensor placement, data acquisition, data analysis.

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1414 Rapid Finite-Element Based Airport Pavement Moduli Solutions using Neural Networks

Authors: Kasthurirangan Gopalakrishnan, Marshall R. Thompson, Anshu Manik

Abstract:

This paper describes the use of artificial neural networks (ANN) for predicting non-linear layer moduli of flexible airfield pavements subjected to new generation aircraft (NGA) loading, based on the deflection profiles obtained from Heavy Weight Deflectometer (HWD) test data. The HWD test is one of the most widely used tests for routinely assessing the structural integrity of airport pavements in a non-destructive manner. The elastic moduli of the individual pavement layers backcalculated from the HWD deflection profiles are effective indicators of layer condition and are used for estimating the pavement remaining life. HWD tests were periodically conducted at the Federal Aviation Administration-s (FAA-s) National Airport Pavement Test Facility (NAPTF) to monitor the effect of Boeing 777 (B777) and Beoing 747 (B747) test gear trafficking on the structural condition of flexible pavement sections. In this study, a multi-layer, feed-forward network which uses an error-backpropagation algorithm was trained to approximate the HWD backcalculation function. The synthetic database generated using an advanced non-linear pavement finite-element program was used to train the ANN to overcome the limitations associated with conventional pavement moduli backcalculation. The changes in ANN-based backcalculated pavement moduli with trafficking were used to compare the relative severity effects of the aircraft landing gears on the NAPTF test pavements.

Keywords: Airfield pavements, ANN, backcalculation, newgeneration aircraft

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1413 Effect of Shell Dimensions on Buckling Behavior and Entropy Generation of Thin Welded Shells

Authors: Sima Ziaee, Khosro Jafarpur

Abstract:

Among all mechanical joining processes, welding has been employed for its advantage in design flexibility, cost saving, reduced overall weight and enhanced structural performance. However, for structures made of relatively thin components, welding can introduce significant buckling distortion which causes loss of dimensional control, structural integrity and increased fabrication costs. Different parameters can affect buckling behavior of welded thin structures such as, heat input, welding sequence, dimension of structure. In this work, a 3-D thermo elastic-viscoplastic finite element analysis technique is applied to evaluate the effect of shell dimensions on buckling behavior and entropy generation of welded thin shells. Also, in the present work, the approximated longitudinal transient stresses which produced in each time step, is applied to the 3D-eigenvalue analysis to ratify predicted buckling time and corresponding eigenmode. Besides, the possibility of buckling prediction by entropy generation at each time is investigated and it is found that one can predict time of buckling with drawing entropy generation versus out of plane deformation. The results of finite element analysis show that the length, span and thickness of welded thin shells affect the number of local buckling, mode shape of global buckling and post-buckling behavior of welded thin shells.

Keywords: Buckling behavior, Elastic viscoplastic model, Entropy generation, Finite element method, Shell dimensions.

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1412 Structural Analysis of Stiffened FGM Thick Walled Cylinders by Application of a New Cylindrical Super Element

Authors: S. A. Moeini, M. T.Ahmadian

Abstract:

Structural behavior of ring stiffened thick walled cylinders made of functionally graded materials (FGMs) is investigated in this paper. Functionally graded materials are inhomogeneous composites which are usually made from a mixture of metal and ceramic. The gradient compositional variation of the constituents from one surface to the other provides an elegant solution to the problem of high transverse shear stresses that are induced when two dissimilar materials with large differences in material properties are bonded. FGM formation of the cylinder is modeled by power-law exponent and the variation of characteristics is supposed to be in radial direction. A finite element formulation is derived for the analysis. According to the property variation of the constituent materials in the radial direction of the wall, it is not convenient to use conventional elements to model and analyze the structure of the stiffened FGM cylinders. In this paper a new cylindrical super-element is used to model the finite element formulation and analyze the static and modal behavior of stiffened FGM thick walled cylinders. By using this super-element the number of elements, which are needed for modeling, will reduce significantly and the process time is less in comparison with conventional finite element formulations. Results for static and modal analysis are evaluated and verified by comparison to finite element formulation with conventional elements. Comparison indicates a good conformity between results.

Keywords: FGMs, Modal analysis, Static analysis, Stiffened cylinders.

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1411 The Gasoil Hydrofining Kinetics Constants Identification

Authors: C. Patrascioiu, V. Matei, N. Nicolae

Abstract:

The paper describes the experiments and the kinetic parameters calculus of the gasoil hydrofining. They are presented experimental results of gasoil hidrofining using Mo and promoted with Ni on aluminum support catalyst. The authors have adapted a kinetic model gasoil hydrofining. Using this proposed kinetic model and the experimental data they have calculated the parameters of the model. The numerical calculus is based on minimizing the difference between the experimental sulf concentration and kinetic model estimation.

Keywords: Hydrofining, kinetic, modeling, optimization.

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1410 Determination of Post-Failure Characteristic Behaviour of Rocks under Conventional Method Based on the Mechanism of Rock Deformation Process

Authors: Victor Abioye Akinbinu

Abstract:

This work is intended to study the post-failure characteristic behaviour of rocks and the techniques of controlling the post-failure regime based on the mechanism of rocks deformation process. It is impossible to determine the post-failure regime of rocks using conventional laboratory testing equipment. This is because most testing machines are soft and therefore no information can be obtained after the peak load. Stress-strain deformation tests were conducted using both conventional and unconventional method (i.e. the closed loop servo-controlled testing machine) in accordance to ISRM standard. Normalised pre-failure curves were constructed to show the stages in the deformation process. The first type contains the Class I and progress to Class II with low strength soft brittle rocks. The second type shows entirely Class II characteristic behaviour. The third type is extremely brittle under axial loading, resulted in explosive failure, so its class could not be determined. The difficulty in obtaining the post-failure curves increases as the total volumetric strain approaches a positive value. The author’s use of normalised pre-failure curves enables identification of additional type of deformation process with very brittle response under axial loading. Testing the third type without confinement could cause equipment damage. Identification of the deformation process with the rock classes using conventional test could guide the personnel conducting tests using closed-loop servo-controlled system, to avoid equipment damage when testing rocks with third type deformation process so that testing is performed safely. It has also improved our understanding on total specimen failure and brittleness of rocks (e.g. brittle for Class II and less brittle or ductile for Class I).

Keywords: Closed-loop servo-controlled system, conventional testing equipment, deformation process, post-failure, pre-failure normalised curves, rock classes.

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1409 Exploring Dimensionality, Systematic Mutations and Number of Contacts in Simple HP ab-initio Protein Folding Using a Blackboard-based Agent Platform

Authors: Hiram I. Beltrán, Arturo Rojo-Domínguez, Máximo Eduardo Sánchez Gutiérrez, Pedro Pablo González Pérez

Abstract:

A computational platform is presented in this contribution. It has been designed as a virtual laboratory to be used for exploring optimization algorithms in biological problems. This platform is built on a blackboard-based agent architecture. As a test case, the version of the platform presented here is devoted to the study of protein folding, initially with a bead-like description of the chain and with the widely used model of hydrophobic and polar residues (HP model). Some details of the platform design are presented along with its capabilities and also are revised some explorations of the protein folding problems with different types of discrete space. It is also shown the capability of the platform to incorporate specific tools for the structural analysis of the runs in order to understand and improve the optimization process. Accordingly, the results obtained demonstrate that the ensemble of computational tools into a single platform is worthwhile by itself, since experiments developed on it can be designed to fulfill different levels of information in a self-consistent fashion. By now, it is being explored how an experiment design can be useful to create a computational agent to be included within the platform. These inclusions of designed agents –or software pieces– are useful for the better accomplishment of the tasks to be developed by the platform. Clearly, while the number of agents increases the new version of the virtual laboratory thus enhances in robustness and functionality.

Keywords: genetic algorithms, multi-agent systems, bioinformatics, optimization, protein folding, structural biology.

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1408 Pronominal Anaphora Processing

Authors: Anna Maria Di Sciullo

Abstract:

Discourse pronominal anaphora resolution must be part of any efficient information processing systems, since the reference of a pronoun is dependent on an antecedent located in the discourse. Contrary to knowledge-poor approaches, this paper shows that syntax-semantic relations are basic in pronominal anaphora resolution. The identification of quantified expressions to which pronouns can be anaphorically related provides further evidence that pronominal anaphora is based on domains of interpretation where asymmetric agreement holds.

Keywords: asymmetric agreement, pronominal anaphora, quantifiers and indefinite expressions.

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