Search results for: D. N. Reddy
143 Preparation and Evaluation of Zidovudine Nanoparticles
Authors: D. R. Rama Brahma Reddy, A. Vijaya Sarada Reddy
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Nanoparticles represent a promising drug delivery system of controlled and targeted drug release. They are specially designed to release the drug in the vicinity of target tissue. The aim of this study was to prepare and evaluate polymethacrylic acid nanoparticles containing Zidovudine in different drug to polymer ratio by nanoprecipitation method. SEM indicated that nanoparticles have a discrete spherical structure without aggregation. The average particle size was found to be 120 ± 0.02 - 420 ± 0.05 nm. The particle size of the nanoparticles was gradually increased with increase in the proportion of polymethacrylic acid polymer. The drug content of the nanoparticles was increasing on increasing polymer concentration up to a particular concentration. No appreciable difference was observed in the extent of degradation of product during 60 days in which, nanoparticles were stored at various temperatures. FT-IR studies indicated that there was no chemical interaction between drug and polymer and stability of drug. The in-vitro release behavior from all the drug loaded batches was found to be zero order and provided sustained release over a period of 24 h. The developed formulation overcome and alleviates the drawbacks and limitations of Zidovudine sustained release formulations and could possibility be advantageous in terms of increased bio availability of Zidovudine.Keywords: nanoparticles, zidovudine, biodegradable, polymethacrylic acid
Procedia PDF Downloads 626142 Study of Interaction between Recycled Asphalt Pavement (RAP) Material and Virgin Material
Authors: G. Bharath, K. S. Reddy, Vivek Tandon, M. Amaranatha Reddy
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This paper presents the details of a study conducted to evaluate the interaction between recycled binder and fresh binder in Recycled Asphalt Pavement (RAP) mixes. When RAP is mixed with virgin aggregates in the presence of fresh binder there will be partial blending in a hot mix asphalt mixture. A recent approach used by some researchers for studying the degree of blending of RAP binder with virgin binder has been adopted in this study. Dense Bituminous Macadam mix of Ministry of Road Transport of India with a nominal maximum aggregate size of 19 mm was studied. Two proportions of RAP-20% and 35% and two types of virgin binders – viscosity grade VG10 and VG30 were considered. Design binder contents were determined for all the four types of mixes (two RAP contents and two virgin binders) as per Marshall mix design procedure. The degree of blending of RAP and virgin binders was evaluated in terms of the complex modulus of the binder. Laboratory test results showed that with an increase in RAP content, the degree of blending decreases. Better blending was observed for softer grade binder (VG10).Keywords: blending, complex modulus, recycled asphalt pavement, virgin binder
Procedia PDF Downloads 432141 Disaster and Crisis Management Using Geographical Information System (GIS) during the Operation and Maintenance Stages of the Hyderabad Metro Rail in India
Authors: Sai Rajeev Reddy, Ishita Roy, M. Anji Reddy
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The paper describes the importance of preventive measures and immediate Emergency logistics during accidents and unfortunate Disasters for the Hyderabad Metro Rails in their various stages of construction. This is the need of the modern generation where accidents, explosions, attacks and sudden crisis are frequent casualties which take huge tolls of life in the present world. The paper utilizes the workflow and application of Geographical information System (GIS) to provide information about problems and crisis structures for efficient Metro Transportation in the city. The study analyzes the difficulties and problems which cause accidents during operation and maintenance stages of the Metro Rail. The paper focuses upon the intermediate and firsthand information of Crisis with the help of GIS technology to share Disaster data for effective measures by the Cyber Police stations, Emergency Responders, Hospitals and First Aid Centre to act immediately and save lives. The results and conclusions have nevertheless proved very informative and useful for the safety board authorities of the Hyderabad Metro Rail. The operation and Maintenance are integral stages in the development of any Multipurpose transportation Projects and are usually prone to various Disasters and tragedies. Hence, the GIS technologies help in distribution of information among the masses with the web Technologies and advanced software developed to prevent and manage crisis widely and in a cost-benefits manner.Keywords: Geographical Information System, emergency assessment, accident zones, surveillance
Procedia PDF Downloads 567140 Quantification of Dowel-Concrete Interaction in Jointed Plain Concrete Pavements Using 3D Numerical Simulation
Authors: Lakshmana Ravi Raj Gali, K. Sridhar Reddy, M. Amaranatha Reddy
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Load transfer between adjacent slabs of the jointed plain concrete pavement (JPCP) system is inevitable for long-lasting performance. Dowel bars are generally used to ensure sufficient degree of load transfer, in addition to the load transferred by aggregate interlock mechanism at the joints. Joint efficiency is the measure of joint quality, a major concern and therefore the dowel bar system should be designed and constructed well. The interaction between dowel bars and concrete that includes various parameters of dowel bar and concrete will explain the degree of joint efficiency. The present study focuses on the methodology of selecting contact stiffness, which quantifies dowel-concrete interaction. In addition, a parametric study which focuses on the effect of dowel diameter, dowel shape, the spacing between dowel bars, joint opening, the thickness of the slab, the elastic modulus of concrete, and concrete cover on contact stiffness was also performed. The results indicated that the thickness of the slab is most critical among various parameters to explain the joint efficiency. Further displacement equivalency method was proposed to find out the contact stiffness. The proposed methodology was validated with the available field surface deflection data collected by falling weight deflectometer (FWD).Keywords: contact stiffness, displacement equivalency method, Dowel-concrete interaction, joint behavior, 3D numerical simulation
Procedia PDF Downloads 152139 Investigation on Biomass as an Alternate Source for Power Generation
Authors: Narsimhulu Sanke, D. N. Reddy
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The purpose of the paper is to discuss the biomass as a renewable source of energy for power generation. The setup is designed and fabricated in the Centre for Energy Technology (CET) and four different fuels are tested in the laboratory, but here the focus is on wood blocks (fuel) combustion with temperature, gas composition percentage by volume and the heating values.Keywords: biomass, downdraft gasifier, power generation, renewable energy sources
Procedia PDF Downloads 544138 3D Numerical Simulation of Undoweled and Uncracked Joints in Short Paneled Concrete Pavements
Authors: K. Sridhar Reddy, M. Amaranatha Reddy, Nilanjan Mitra
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Short paneled concrete pavement (SPCP) with shorter panel size can be an alternative to the conventional jointed plain concrete pavements (JPCP) at the same cost as the asphalt pavements with all the advantages of concrete pavement with reduced thickness, less chance of mid-slab cracking and or dowel bar locking so common in JPCP. Cast-in-situ short concrete panels (short slabs) laid on a strong foundation consisting of a dry lean concrete base (DLC), and cement treated subbase (CTSB) will reduce the thickness of the concrete slab to the order of 180 mm to 220 mm, whereas JPCP was with 280 mm for the same traffic. During the construction of SPCP test sections on two Indian National Highways (NH), it was observed that the joints remain uncracked after a year of traffic. The undoweled and uncracked joints load transfer variability and joint behavior are of interest with anticipation on its long-term performance of the SPCP. To investigate the effects of undoweled and uncracked joints on short slabs, the present study was conducted. A multilayer linear elastic analysis using 3D finite element package for different panel sizes with different thicknesses resting on different types of solid elastic foundation with and without temperature gradient was developed. Surface deflections were obtained from 3D FE model and validated with measured field deflections from falling weight deflectometer (FWD) test. Stress analysis indicates that flexural stresses in short slabs are decreased with a decrease in panel size and increase in thickness. Detailed evaluation of stress analysis with the effects of curling behavior, the stiffness of the base layer and a variable degree of load transfer, is underway.Keywords: joint behavior, short slabs, uncracked joints, undoweled joints, 3D numerical simulation
Procedia PDF Downloads 182137 The Temperature Influence for Gasification in the Advanced Biomass Gasifier
Authors: Narsimhulu Sanke, D. N. Reddy
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The paper is to discuss about the influence of the temperature in the advanced biomass gasifier for gasification, when tested four different biomass fuels individually in the gasification laboratory of Centre for Energy Technology (CET). The gasifier is developed in CET to test any kind of biomass fuel for gasification without changing the gasifier. The gasifier can be used for batch operations and observed and found that there were no operational problems.Keywords: biomass fuels, temperature, advanced downdraft gasifier, tar, renewable energy sources
Procedia PDF Downloads 494136 Single Feed Circularly Polarized Poly Fractal Antenna for Wireless Applications
Authors: V. V. Reddy, N. V. Sarma
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A circularly polarized fractal boundary microstrip antenna is presented. The sides of a square patch along x-axis, y-axis are replaced with Minkowski and Koch curves correspondingly. By using the fractal curves as edges, asymmetry in the structure is created to excite two orthogonal modes for circular polarization (CP) operation. The indentation factors of the fractal curves are optimized for pure CP. The simulated results of the novel poly fractal antenna are demonstrated.Keywords: fractal, circular polarization, Minkowski, Koch
Procedia PDF Downloads 356135 Maximizing the Efficiency of Knowledge Management Systems
Authors: Tori Reddy Dodla, Laura Ann Jones
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The objective of this study was to propose strategies to improve the efficiency of Knowledge Management Systems (KMS). This study highlights best practices from various industries to create an overall summary of Knowledge Management (KM) and efficiency in organizational performance. Results indicated eleven best practices for maximizing the efficiency of organizational KMS that can be divided into four categories: Designing the KMS, Identifying Case Studies, Implementing the KMS, and Promoting adoption and usage. Our findings can be used as a foundation for scholars to conduct further research on KMS efficiency.Keywords: artificial intelligence, knowledge management efficiency, knowledge management systems, organizational performance
Procedia PDF Downloads 113134 Isolation and Synthesis of 1’-S-1’-Acetoxycavicol Acetate as Potent Antidandruff Agent
Authors: M. Vijaya Bhaskar Reddy
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The air-dried and powdered methanol solvent extraction of the rhizomes of Alpinia galangal is subjected to bio-assay guided fractionation and isolation yielded a known compound namely, 1'-S-1'-Acetoxychavicol acetate (1). The isolated known compound has been identified based on the physical, spectral data (IR, ¹H, ¹³C, NMR and mass spectroscopy) and comparison with an authentic sample. Finally isolated 1'-S-1'-Acetoxychavicol acetate (1) was confirmed by synthesis. The crude methanol extract and identified known compound (1) were tested for antidandruff property against Malassezia furfur showed with MIC 1000 µg/mL and 7.81 µg/mL, respectively.Keywords: Alpinia galanga, isolation, 1'-S-1'-Acetoxychavicol acetate, antidandruff activity, Malassezia furfur
Procedia PDF Downloads 171133 Rb-Modified Few-Layered Graphene for Gas Sensing Application
Authors: Vasant Reddy, Shivani A. Singh, Pravin S. More
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In the present investigation, we demonstrated the fabrication of few-layers of graphene sheets with alkali metal i.e. Rb-G using chemical route method. The obtained materials were characterized by means of chemical, structural and electrical techniques, using the ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), scanning electron microscopy (SEM) and 4 points probe, respectively. The XRD studies were carried out to understand the phase of the samples where we found a sharp peak of Rb-G at 26.470. UV-Spectroscopy of Graphene and Rb-modified graphene samples shows the absorption peaks at ~248 nm and ~318 nm respectively. These analyses show that this modified material can be useful for gas sensing applications and to be used in diverse areas.Keywords: chemical route, graphene, gas sensing, UV-spectroscopy
Procedia PDF Downloads 270132 Providing Security to Private Cloud Using Advanced Encryption Standard Algorithm
Authors: Annapureddy Srikant Reddy, Atthanti Mahendra, Samala Chinni Krishna, N. Neelima
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In our present world, we are generating a lot of data and we, need a specific device to store all these data. Generally, we store data in pen drives, hard drives, etc. Sometimes we may loss the data due to the corruption of devices. To overcome all these issues, we implemented a cloud space for storing the data, and it provides more security to the data. We can access the data with just using the internet from anywhere in the world. We implemented all these with the java using Net beans IDE. Once user uploads the data, he does not have any rights to change the data. Users uploaded files are stored in the cloud with the file name as system time and the directory will be created with some random words. Cloud accepts the data only if the size of the file is less than 2MB.Keywords: cloud space, AES, FTP, NetBeans IDE
Procedia PDF Downloads 206131 Robustness of MIMO-OFDM Schemes for Future Digital TV to Carrier Frequency Offset
Authors: D. Sankara Reddy, T. Kranthi Kumar, K. Sreevani
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This paper investigates the impact of carrier frequency offset (CFO) on the performance of different MIMO-OFDM schemes with high spectral efficiency for next generation of terrestrial digital TV. We show that all studied MIMO-OFDM schemes are sensitive to CFO when it is greater than 1% of intercarrier spacing. We show also that the Alamouti scheme is the most sensitive MIMO scheme to CFO.Keywords: modulation and multiplexing (MIMO-OFDM), signal processing for transmission carrier frequency offset, future digital TV, imaging and signal processing
Procedia PDF Downloads 487130 Wired Network Services in Mobile Phones
Authors: Subhash Reddy
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Mobile communication in today’s world means a lot to the human kind, through this many deals are made and others are broken, within seconds. That is because of our sophisticated methods of transporting the data at very high speeds and to very long distances, within no time. That is also because we kept on changing the method of serving the connections as the no of connections kept on increasing, that has led to many methods like TDMA, CDMA, and FDMA, etc. in wireless communications. And also the areas, where the connections are provided are also divided into CELLS, which are the basic blocks for cellular communications. Along with the wireless network, providing a wired network in mobile phones would serve as a very good alternative and would divert the extra traffic of a cell, so that a CELL which is providing wireless network can operate more efficiently.Keywords: CDMA, FDMA, TDMA, CELL
Procedia PDF Downloads 486129 Thermal Radiation and Chemical Reaction Effects on MHD Casson Fluid Past a Permeable Stretching Sheet in a Porous Medium
Authors: Y. Sunita Rani, Y. Hari Krishna, M. V. Ramana Murthy, K. Sudhaker Reddy
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This article studied effects of radiation and chemical reaction on MHD casson fluoid flow past a Permeable Stretching Sheet in a Porous Medium. Suitable transformations are considered to transform the governing partial differential equations as ordinary ones and then solved by the numerical procedures like Runge- Kutta – Fehlberg shooting technique method. The effects of various governing parameters, on the velocity, temperature and concentration are displayed through graphs and discussed numerically.Keywords: MHD, Casson fluid, porous medium, permeable stretching sheet
Procedia PDF Downloads 127128 Laboratory Evaluation of Gilsonite Modified Bituminous Mixes
Authors: R. Vishnu, K. S. Reddy, Amrendra Kumar
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The present guideline for the construction of flexible pavement in India, IRC 37: 2012 recommends to use viscous grade VG 40 bitumen in both wearing and binder bituminous layers. However, most of the bitumen production plants in India are unable to produce the air-blown VG40 grade bitumen. This requires plant’s air-blowing technique modification, and often the manufactures finds it as uneconomical. In this context, stiffer grade bitumen can be produced if bitumen is modified. Gilsonite, which is naturally occurring asphalt have been found to be used for increasing the stiffness of binders. The present study evaluates the physical, rheological characteristics of Gilsonite modified binders and the performance characteristics of these binders when used in the mix.Keywords: bitumen, gilsonite, stiffness, laboratory evaluation
Procedia PDF Downloads 465127 Morphology and Mineralogy of Acid Treated Soil
Authors: P. Hari Prasad Reddy, C. H. Rama Vara Prasad, G. Kalyan Kumar
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This paper presents the morphological and mineralogical changes occurring in the soil due to immediate and prolonged interaction with different concentrations of phosphoric acid and sulphuric acid. In order to assess the effect of acid contamination, a series of sediment volume, scanning electron microscopy and X-ray diffraction analysis tests were carried out on soil samples were exposed to different concentrations (1N, 4N and 8N) of phosphoric and sulphuric acid. Experimental results show that both acids showed severe morphological and mineralogical changes with synthesis of neogenic formations mainly at higher concentrations (4N and 8N) and at prolonged duration of interaction (28 and 80 days).Keywords: phosphoric acid, scanning electron microscopy, sulphuric acid, x-ray diffraction analysis
Procedia PDF Downloads 428126 Multiband Multipolarized Planar Antenna for WLAN/WiMAX Applications
Authors: Sanjeeva Reddy, D. Vakula
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A single layer, multi-band triangular patch antenna is proposed for WLAN/WiMAX applications with different polarization requirements. This probe feed patch is integrated with arc shaped slit to achieve circular polarized (CP) and linearly polarized (LP) radiation characteristics. The main contribution of antenna is to resonate the frequencies of 2.4 GHz with CP and 3.5 GHz, 5.28 GHz with LP. The design procedure of antenna is described and the performance is validated using measurements. Size of antenna is also reduced and provides stable gain at all resonant frequencies. Proposed structure also provides better enhancement in terms of 10-dB impedance bandwidth, achieved gain of 5.1, 5.6, and 2.9 dBi at respective bands.Keywords: circular polarization, arc shaped slit, multi band antenna, triangular patch antenna, axial ratio
Procedia PDF Downloads 397125 Phasor Measurement Unit Based on Particle Filtering
Authors: Rithvik Reddy Adapa, Xin Wang
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Phasor Measurement Units (PMUs) are very sophisticated measuring devices that find amplitude, phase and frequency of various voltages and currents in a power system. Particle filter is a state estimation technique that uses Bayesian inference. Particle filters are widely used in pose estimation and indoor navigation and are very reliable. This paper studies and compares four different particle filters as PMUs namely, generic particle filter (GPF), genetic algorithm particle filter (GAPF), particle swarm optimization particle filter (PSOPF) and adaptive particle filter (APF). Two different test signals are used to test the performance of the filters in terms of responsiveness and correctness of the estimates.Keywords: phasor measurement unit, particle filter, genetic algorithm, particle swarm optimisation, state estimation
Procedia PDF Downloads 9124 Optimum Stratification of a Skewed Population
Authors: D. K. Rao, M. G. M. Khan, K. G. Reddy
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The focus of this paper is to develop a technique of solving a combined problem of determining Optimum Strata Boundaries (OSB) and Optimum Sample Size (OSS) of each stratum, when the population understudy is skewed and the study variable has a Pareto frequency distribution. The problem of determining the OSB is formulated as a Mathematical Programming Problem (MPP) which is then solved by dynamic programming technique. A numerical example is presented to illustrate the computational details of the proposed method. The proposed technique is useful to obtain OSB and OSS for a Pareto type skewed population, which minimizes the variance of the estimate of population mean.Keywords: stratified sampling, optimum strata boundaries, optimum sample size, pareto distribution, mathematical programming problem, dynamic programming technique
Procedia PDF Downloads 455123 Design and Development of Chassis Made of Composite Material
Authors: P. Ravinder Reddy, Chaitanya Vishal Nalli, B. Tulja Lal, Anusha Kankanala
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The chassis frame of an automobile with different sections have been considered for different loads. The orthotropic materials are selected to get the stability by varying fiber angle, fiber thickness, laminates, fiber properties, matrix properties and elastic ratios. The geometric model of chassis frame is carried out with parametric modelling approach. The analysis of chassis frame is carried out with ANSYS FEA software. The static and dynamic analysis of chassis frame is carried out by varying geometric parameters, orthotropic properties, materials and various sections. The static and dynamic response is discussed in detail in different sections.Keywords: chassis frame, dynamic response, geometric model, orthotropic materials
Procedia PDF Downloads 334122 Characterization of Number of Subgroups of Finite Groups
Authors: Khyati Sharma, A. Satyanarayana Reddy
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The topic of how many subgroups exist within a certain finite group naturally arises in the study of finite groups. Over the years, different researchers have investigated this issue from a variety of angles. The significant contributions of the key mathematicians over the time have been summarized in this article. To this end, we classify finite groups into three categories viz. (a) Groups for which the number of subgroups is less than |G|, (b) equals to |G|, and finally, (c) greater than |G|. Because every element of a finite group generates a cyclic subgroup, counting cyclic subgroups is the most important task in this endeavor. A brief survey on the number of cyclic subgroups of finite groups is also conducted by us. Furthermore, we also covered certain arithmetic relations between the order of a finite group |G| and the number of its distinct cyclic subgroups |C(G)|. In order to provide pertinent context and possibly reveal new novel areas of potential research within the field of research on finite groups, we finally pose and solicit a few open questions.Keywords: abstract algebra, cyclic subgroup, finite group, subgroup
Procedia PDF Downloads 120121 Structural and Electromagnetic Properties of CoFe2O4-ZrO2 Nanocomosites
Authors: Ravinder Reddy Butreddy, Sadhana Katlakunta
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The nanocomposites of CoFe2O4-xZrO2 with different loadings of ZrO2 (x = 0.025, 0.05, 0.075, 0.1 and 1.5) were prepared using ball mill method. All the samples were prepared at 980°C/1h using microwave sintering method. The x-ray diffraction patterns show the existence of tetragonal/monoclinic phase of ZrO2 and cubic phase of CoFe2O4. The effects of ZrO2 on structural and microstructural properties of CoFe2O4 composite ceramics were investigated. It is observed that the density of the composite decreases and porosity increases with x. The magnetic properties such as saturation magnetization (Ms), and Coercive field were calculated at room temperature. The Ms is decreased with x while coercive field is increased with x. The dielectric parameters exhibit the relaxation behavior in high-frequency region and showing increasing trend with ZrO2 concentration, showing suitableKeywords: dielectric properties, magnetic properties, microwave sintering, nanocomposites
Procedia PDF Downloads 239120 Gas Holdups in a Gas-Liquid Upflow Bubble Column With Internal
Authors: C. Milind Caspar, Valtonia Octavio Massingue, K. Maneesh Reddy, K. V. Ramesh
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Gas holdup data were obtained from measured pressure drop values in a gas-liquid upflow bubble column in the presence of string of hemispheres promoter internal. The parameters that influenced the gas holdup are gas velocity, liquid velocity, promoter rod diameter, pitch and base diameter of hemisphere. Tap water was used as liquid phase and nitrogen as gas phase. About 26 percent in gas holdup was obtained due to the insertion of promoter in in the present study in comparison with empty conduit. Pitch and rod diameter have not shown any influence on gas holdup whereas gas holdup was strongly influenced by gas velocity, liquid velocity and hemisphere base diameter. Correlation equation was obtained for the prediction of gas holdup by least squares regression analysis.Keywords: bubble column, gas-holdup, two-phase flow, turbulent promoter
Procedia PDF Downloads 106119 Greening of Supply Chains: Benefits and Challenges Faced
Authors: Anurag Reddy Ramireddy, Abrar Ahmed, G. Sourya Sri Harsha, Pushkala Muralidharan
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Supply chains have been developing over time since the inception of commercial trade and barter. The Green Supply Chain Management (GSCM) is a powerful way to differentiate a company from its competitors and it can greatly influence the plan success. With increased awareness to corporate responsibility and the requirement to meet the terms with environmental policy, GSCM is becoming increasingly important for companies. This paper explains the concept of green supply chain management, the difference between conventional supply chain management and green supply management and how GSCM benefits organizations while at the same time supporting a sustainable environment system. An effort has also been made to analyse research already done in this field while exploring the challenges and barriers that organizations face in implementing GSCM practices in their existing systems.Keywords: corporate social responsibility, green supply chain management, sustainability
Procedia PDF Downloads 383118 Preparation and Characterization of Photocatalyst for the Conversion of Carbon Dioxide to Methanol
Authors: D. M. Reddy Prasad, Nur Sabrina Binti Rahmat, Huei Ruey Ong, Chin Kui Cheng, Maksudur Rahman Khan, D. Sathiyamoorthy
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Carbon dioxide (CO2) emission to the environment is inevitable which is responsible for global warming. Photocatalytic reduction of CO2 to fuel, such as methanol, methane etc. is a promising way to reduce greenhouse gas CO2 emission. In the present work, Bi2S3/CdS was synthesized as an effective visible light responsive photocatalyst for CO2 reduction into methanol. The Bi2S3/CdS photocatalyst was prepared by hydrothermal reaction. The catalyst was characterized by X-ray diffraction (XRD) instrument. The photocatalytic activity of the catalyst has been investigated for methanol production as a function of time. Gas chromatograph flame ionization detector (GC-FID) was employed to analyze the product. The yield of methanol was found to increase with higher CdS concentration in Bi2S3/CdS and the maximum yield was obtained for 45 wt% of Bi2S3/CdS under visible light irradiation was 20 μmole/g. The result establishes that Bi2S3/CdS is favorable catalyst to reduce CO2 to methanol.Keywords: photocatalyst, CO2 reduction, methanol, visible light, XRD, GC-FID
Procedia PDF Downloads 502117 Effective Texture Features for Segmented Mammogram Images Based on Multi-Region of Interest Segmentation Method
Authors: Ramayanam Suresh, A. Nagaraja Rao, B. Eswara Reddy
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Texture features of mammogram images are useful for finding masses or cancer cases in mammography, which have been used by radiologists. Textures are greatly succeeded for segmented images rather than normal images. It is necessary to perform segmentation for exclusive specification of cancer and non-cancer regions separately. Region of interest (ROI) is most commonly used technique for mammogram segmentation. Limitation of this method is that it is unable to explore segmentation for large collection of mammogram images. Therefore, this paper is proposed multi-ROI segmentation for addressing the above limitation. It supports greatly in finding the best texture features of mammogram images. Experimental study demonstrates the effectiveness of proposed work using benchmarked images.Keywords: texture features, region of interest, multi-ROI segmentation, benchmarked images
Procedia PDF Downloads 311116 Enabling Non-invasive Diagnosis of Thyroid Nodules with High Specificity and Sensitivity
Authors: Sai Maniveer Adapa, Sai Guptha Perla, Adithya Reddy P.
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Thyroid nodules can often be diagnosed with ultrasound imaging, although differentiating between benign and malignant nodules can be challenging for medical professionals. This work suggests a novel approach to increase the precision of thyroid nodule identification by combining machine learning and deep learning. The new approach first extracts information from the ultrasound pictures using a deep learning method known as a convolutional autoencoder. A support vector machine, a type of machine learning model, is then trained using these features. With an accuracy of 92.52%, the support vector machine can differentiate between benign and malignant nodules. This innovative technique may decrease the need for pointless biopsies and increase the accuracy of thyroid nodule detection.Keywords: thyroid tumor diagnosis, ultrasound images, deep learning, machine learning, convolutional auto-encoder, support vector machine
Procedia PDF Downloads 58115 Artificial Intelligence in Global Healthcare: Need for Robust Governance Frameworks
Authors: Sandeep Reddy, Sonia Allan, Simon Coghlan, Paul Cooper
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Artificial Intelligence (AI) and its application in medicine has generated ample interest amongst policymakers and clinicians. Successes with AI in medical imaging interpretation and clinical decision support are paving the way for its incorporation into routine healthcare delivery. While there has been a focus on the development of ethical principles to guide its application in healthcare, challenges of this application go beyond what ethics principles can address thus requiring robust governance frameworks. Also, while ethical challenges of medical artificial intelligence are being discussed, the ethics of deploying AI in lower-income countries receive less attention than in other developed economies. This creates an imperative not only for sound ethical guidelines but also for robust governance frameworks to regulate AI in medicine around the world. In this article, we discuss what components need to be considered in developing these governance frameworks and who should lead this worldwide effort.Keywords: artificial intelligence, global health, governance, ethics
Procedia PDF Downloads 152114 Effect of Gamma Irradiation on Structural and Optical Properties of ZnO/Mesoporous Silica Nanocomposite
Authors: K. Sowri Babu, P. Srinath, N. Rajeswara Rao, K. Venugopal Reddy
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The effect of gamma ray irradiation on morphology and optical properties of ZnO/Mesoporous silica (MPS) nanocomposite was studied. The ZnO/MPS nanocomposite was irradiated with gamma rays of doses 30, 60, and 90 kGy and dose-rate of irradiation was 0.15 kGy/hour. Irradiated samples are characterized with FE-SEM, FT-IR, UV-vis, and Photoluminescence (PL) spectrometers. SEM pictures showed that morphology changed from spherical to flake like morphology. UV-vis analysis showed that the band gap increased with increase of gamma ray irradiation dose. This enhancement of the band gap is assigned to the depletion of oxygen vacancies with irradiation. The intensity of PL peak decreased gradually with increase of gamma ray irradiation dose. The decrease in PL intensity is attributed to the decrease of oxygen vacancies at the interface due to poor interface and improper passivation between ZnO/MPS.Keywords: ZnO nanoparticles, nanocomposites, mesoporous silica, photoluminescence
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