Search results for: textile damage
1265 In vitro Effects of Viscum album on the Functionality of Rabbit Spermatozoa
Authors: Marek Halenár, Eva Tvrdá, Simona Baldovská, Ľubomír Ondruška, Peter Massányi, Adriana Kolesárová
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This study aimed to assess the in vitro effects of different concentrations of the Viscum album extract on the motility, viability, and reactive oxygen species (ROS) production by rabbit spermatozoa during different time periods (0, 2, and 8h). Spermatozoa motility was assessed by using the CASA (Computer aided sperm analysis) system. Cell viability was evaluated by using the metabolic activity MTT assay, and the luminol-based luminometry was applied to quantify the ROS formation. The CASA analysis revealed that low Viscum concentrations were able to prevent a rapid decline of spermatozoa motility, especially in the case of concentrations ranging between 1 and 5 µg/mL (P<0.05 with respect to time 8h). At the same time, concentrations ranging between 1 and 100 µg/mL of the extract led to a significant preservation of the cell viability (P<0.05 in case of 5, 50 and 100 µg/mL; P<0.01 with respect to 1 and 10 µg/mL, time 8h). 1 and 5 µg/mL of the extract exhibited antioxidant characteristics, translated into a significant reduction of the ROS production, particularly notable at time 8h (P<0.01). The results indicate that the Viscum extract is capable of delaying the damage inflicted to the spermatozoon by the in vitro environment.Keywords: CASA, mistletoe, mitochondrial activity, motility, reactive oxygen species, rabbits, spermatozoa, Viscum album
Procedia PDF Downloads 3941264 Determining Inventory Replenishment Policy for Major Component in Assembly-to-Order of Cooling System Manufacturing
Authors: Tippawan Nasawan
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The objective of this study is to find the replenishment policy in Assembly-to-Order manufacturing (ATO) which some of the major components have lead-time longer than customer lead-time. The variety of products, independent component demand, and long component lead-time are the difficulty that has resulted in the overstock problem. In addition, the ordering cost is trivial when compared to the cost of material of the major component. A conceptual design of the Decision Supporting System (DSS) has introduced to assist the replenishment policy. Component replenishment by using the variable which calls Available to Promise (ATP) for making the decision is one of the keys. The Poisson distribution is adopted to realize demand patterns in order to calculate Safety Stock (SS) at the specified Customer Service Level (CSL). When distribution cannot identify, nonparametric will be applied instead. The test result after comparing the ending inventory between the new policy and the old policy, the overstock has significantly reduced by 46.9 percent or about 469,891.51 US-Dollars for the cost of the major component (material cost only). Besides, the number of the major component inventory is also reduced by about 41 percent which helps to mitigate the chance of damage and keeping stock.Keywords: Assembly-to-Order, Decision Supporting System, Component replenishment , Poisson distribution
Procedia PDF Downloads 1271263 Efficient HVAC System in Green Building Design
Authors: Omid Khabiri, Maryam Ghavami
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Buildings designed and built as high performance, sustainable or green are the vanguard in a movement to make buildings more energy efficient and less environmentally harmful. Although Heating, Ventilating, and Air Conditioning (HVAC) systems offer many opportunities for recovery and re-use of thermal energy; however, the amount of energy used annually by these systems typically ranges from 40 to 60 percent of the overall energy consumption in a building, depending on the building design, function, condition, climate, and the use of renewable energy strategies. HVAC systems may also damage the environment by unnecessary use of non-renewable energy sources, which contribute to environmental pollution, and by creating noise and discharge of contaminated water and air containing chemicals, lubricating oils, refrigerants, heat transfer fluids, and particulate (gases matter). In fact, HVAC systems will significantly impact how “green” a building is, where an efficient HVAC system design can result in considerable energy, emissions and cost savings as well as providing increased user thermal comfort. This paper presents the basic concepts of green building design and discusses the role of efficient HVAC system and practical strategies for ensuring high performance sustainable buildings in design and operation.Keywords: green building, hvac system, design strategies, high-performance equipment, efficient technologies
Procedia PDF Downloads 5771262 Ground Water Contamination by Tannery Effluents and Its Impact on Human Health in Peshawar, Pakistan
Authors: Fawad Ali, Muhammad Ateeq, Ikhtiar Khan
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Ground water, a major source of drinking water supply in Peshawar has been severely contaminated by leather tanning industry. Effluents from the tanneries contain high concentration of chromium besides several other chemical species. Release of untreated effluents from the tanning industry has severely damaged surface and ground water, agriculture soil as well as vegetables and crops. Chromium is a well-known carcinogenic and mutagenic agent. Once in the human food chain, it causes multiple problems to the exposed population including various types of cancer, skin dermatitis, and DNA damage. In order to assess the extent of chromium and other heavy metals contamination, water samples were analyzed for heavy metals using Graphite Furnace Atomic Absorption Spectrometer (GFAAS, Analyst 700, Perkin Elmer). Total concentration of chromium was above the permissible limit (0.048 mg/l) in 85% of the groundwater (drinking water) samples. The concentration of cobalt, manganese, cadmium, nickel, lead, zinc and iron was also determined in the ground water, surface water, agriculture soil, and vegetables samples from the affected area.Keywords: heavy metals, soil, groundwater, tannery effluents, food chain
Procedia PDF Downloads 3461261 Synthesis and Characterization of Cobalt Oxide and Cu-Doped Cobalt Oxide as Photocatalyst for Model Dye Degradation
Authors: Vrinda P. S. Borker
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Major water pollutants are dyes from effluents of industries. Different methods have been tried to degrade or treat the effluent before it is left to the environment. In order to understand the degradation process and later apply it to effluents, solar degradation study of methylene blue (MB) and methyl red (MR), the model dyes was carried out in the presence of photo-catalysts, the oxides of cobalt oxide Co₃O₄, and copper doped cobalt oxides (Co₀.₉Cu₀.₁)₃O₄ and (Co₀.₉₅Cu₀.₀₅)₃O₄. They were prepared from oxalate complex and hydrazinated oxalate complex of cobalt as well as mix metals, copper, and cobalt. The complexes were synthesized and characterized by FTIR. Complexes were decomposed to form oxides and were characterized by XRD. They were found to be monophasic. Solar degradation of MR and MB was carried out in presence of these oxides in acidic and basic medium. Degradation was faster in alkaline medium in the presence of Co₃O₄ obtained from hydrazinated oxalate. Doping of nanomaterial oxides modifies their characteristics. Doped cobalt oxides are found to photo-decolourise MR in alkaline media efficiently. In the absence of photocatalyst, solar degradation of alkaline MR does not occur. In acidic medium, MR is minimally decolorized even in the presence of photocatalysts. The industrial textile effluent contains chemicals like NaCl and Na₂CO₃ along with the unabsorbed dye. It is reported that these two chemicals hamper the degradation of dye. The chemicals like K₂S₂O₈ and H₂O₂ are reported to enhance degradation. The solar degradation study of MB in presence of photocatalyst (Co₀.₉Cu₀.₁)₃O₄ and these four chemicals reveals that presence of K₂S₂O₈ and H₂O₂ enhances degradation. It proves that H₂O₂ generates hydroxyl ions required for degradation of dye and the sulphate anion radical being strong oxidant attacks dye molecules leading to its fragmentation rapidly. Thus addition of K₂S₂O₈ and H₂O₂ during solar degradation in presence of (Co₀.₉Cu₀.₁)₃O₄ helps to break the organic moiety efficiently.Keywords: cobalt oxides, Cu-doped cobalt oxides, H₂O₂ in dye degradation, photo-catalyst, solar dye degradation
Procedia PDF Downloads 1781260 Cellular Mechanisms Involved in the Radiosensitization of Breast- and Lung Cancer Cells by Agents Targeting Microtubule Dynamics
Authors: Elsie M. Nolte, Annie M. Joubert, Roy Lakier, Maryke Etsebeth, Jolene M. Helena, Marcel Verwey, Laurence Lafanechere, Anne E. Theron
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Treatment regimens for breast- and lung cancers may include both radiation- and chemotherapy. Ideally, a pharmaceutical agent which selectively sensitizes cancer cells to gamma (γ)-radiation would allow administration of lower doses of each modality, yielding synergistic anti-cancer benefits and lower metastasis occurrence, in addition to decreasing the side-effect profiles. A range of 2-methoxyestradiol (2-ME) analogues, namely 2-ethyl-3-O-sulphamoyl-estra-1,3,5 (10) 15-tetraene-3-ol-17one (ESE-15-one), 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16) were in silico-designed by our laboratory, with the aim of improving the parent compound’s bioavailability in vivo. The main effect of these compounds is the disruption of microtubule dynamics with a resultant mitotic accumulation and induction of programmed cell death in various cancer cell lines. This in vitro study aimed to determine the cellular responses involved in the radiation sensitization effects of these analogues at low doses in breast- and lung cancer cell lines. The oestrogen receptor positive MCF-7-, oestrogen receptor negative MDA-MB-231- and triple negative BT-20 breast cancer cell lines as well as the A549 lung cancer cell line were used. The minimal compound- and radiation doses able to induce apoptosis were determined using annexin-V and cell cycle progression markers. These doses (cell line dependent) were used to pre-sensitize the cancer cells 24 hours prior to 6 gray (Gy) radiation. Experiments were conducted on samples exposed to the individual- as well as the combination treatment conditions in order to determine whether the combination treatment yielded an additive cell death response. Morphological studies included light-, fluorescence- and transmission electron microscopy. Apoptosis induction was determined by flow cytometry employing annexin V, cell cycle analysis, B-cell lymphoma 2 (Bcl-2) signalling, as well as reactive oxygen species (ROS) production. Clonogenic studies were performed by allowing colony formation for 10 days post radiation. Deoxyribonucleic acid (DNA) damage was quantified via γ-H2AX foci and micronuclei quantification. Amplification of the p53 signalling pathway was determined by western blot. Results indicated that exposing breast- and lung cancer cells to nanomolar concentrations of these analogues 24 hours prior to γ-radiation induced more cell death than the compound- and radiation treatments alone. Hypercondensed chromatin, decreased cell density, a damaged cytoskeleton and an increase in apoptotic body formation were observed in cells exposed to the combination treatment condition. An increased number of cells present in the sub-G1 phase as well as increased annexin-V staining, elevation of ROS formation and decreased Bcl-2 signalling confirmed the additive effect of the combination treatment. In addition, colony formation decreased significantly. p53 signalling pathways were significantly amplified in cells exposed to the analogues 24 hours prior to radiation, as was the amount of DNA damage. In conclusion, our results indicated that pre-treatment of breast- and lung cancer cells with low doses of 2-ME analogues sensitized breast- and lung cancer cells to γ-radiation and induced apoptosis more so than the individual treatments alone. Future studies will focus on the effect of the combination treatment on non-malignant cellular counterparts.Keywords: cancer, microtubule dynamics, radiation therapy, radiosensitization
Procedia PDF Downloads 2071259 Solubility of Water in CO2 Mixtures at Pipeline Operation Conditions
Authors: Mohammad Ahmad, Sander Gersen, Erwin Wilbers
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Carbon capture, transport and underground storage have become a major solution to reduce CO2 emissions from power plants and other large CO2 sources. A big part of this captured CO2 stream is transported at high pressure dense phase conditions and stored in offshore underground depleted oil and gas fields. CO2 is also transported in offshore pipelines to be used for enhanced oil and gas recovery. The captured CO2 stream with impurities may contain water that causes severe corrosion problems, flow assurance failure and might damage valves and instrumentations. Thus, free water formation should be strictly prevented. The purpose of this work is to study the solubility of water in pure CO2 and in CO2 mixtures under real pipeline pressure (90-150 bar) and temperature operation conditions (5-35°C). A set up was constructed to generate experimental data. The results show the solubility of water in CO2 mixtures increasing with the increase of the temperature or/and with the increase in pressure. A drop in water solubility in CO2 is observed in the presence of impurities. The data generated were then used to assess the capabilities of two mixture models: the GERG-2008 model and the EOS-CG model. By generating the solubility data, this study contributes to determine the maximum allowable water content in CO2 pipelines.Keywords: carbon capture and storage, water solubility, equation of states, fluids engineering
Procedia PDF Downloads 3021258 Peltier Air Conditioning System for Preventing Ambient Heating: An Alternative to Gas Air Conditioners
Authors: Siamak Eskandari, Neda Ebadi
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After discovering and using Freon as refrigerant in refrigerators and air conditioners, researchers have been working hard to minimize massive environmental damage caused by this type of systems, including ozone depletion, heat production, and urban warming. However, there is a growing concern for global warming and climate change and its impacts on climates. Although gas air conditioners can provide comfort in short term, there are long-term consequences and effects, including global warming, polar ice melting, sea level rising, rising sea surface temperatures, reduction in seasonal precipitation, tropical storms, and drought. In this theoretical and practical study, Peltier electronic chip was used with no gas in the structure and operation. In fact, cooling and heating are based on bipolar electronics. With an innovative method, Peltier air conditioners provide cooling in warm seasons and heating in cold seasons in buildings. Such a system prevents ambient warming. The problem of air circulation between high buildings in large cities and draught will be considerably resolved through the use of the silent fan in the system. In addition, the system is designed and developed in accordance with international standards such as LEED and Energy Star.Keywords: energy, Building cooling and heating, peltier, leed, energy star
Procedia PDF Downloads 1951257 Detection of Latent Fingerprints Recovered from Arson Simulation by a Novel Fluorescent Method
Authors: Somayeh Khanjani, Samaneh Nabavi, Shirin Jalili, Afshin Khara
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Fingerprints are area source of ubiquitous evidence and consequential for establishing identity. The detection and subsequent development of fingerprints are thus inevitable in criminal investigations. This becomes a difficult task in the case of certain extreme conditions like fire. A fire scene may be accidental or arson. The evidence subjected to fire is generally overlooked as there is a misconception that they are damaged. There are several scientific approaches to determine whether the fire was deliberate or not. In such as scenario, fingerprints may be most critical to link the perpetrator to the crime. The reason for this may be the destructive nature of fire. Fingerprints subjected to fire are exposed to high temperatures, soot deposition, electromagnetic radiation, and subsequent water force. It is believed that these phenomena damage the fingerprint. A novel fluorescent and a pre existing small particle reagent were investigated for the same. Zinc carbonates based fluorescent small particle reagent was capable of developing latent fingerprints exposed to a maximum temperature of 800 ̊C. Fluorescent SPR may prove very useful in such cases. Fluorescent SPR reagent based on zinc carbonate is a potential method for developing fingerprints from arson sites. The method is cost effective and non hazardous. This formulation is suitable for developing fingerprints exposed to fire/ arson.Keywords: fingerprint, small particle reagent (SPR), arson, novel fluorescent
Procedia PDF Downloads 4721256 Spatial Occupation of the Wild Boar 'Sus Scrofa Algirus' in the Oasis of Southern Tunisia: The Continental Oasis of Kebili and the Coastal Oasis of Gabes
Authors: Ghandri Aida
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The wild boar ‘Sus scrofa algirus’ is an invasive species that has a significant invasive potential allowing it to colonize the agroecosystems of southern Tunisia. In fact, these agroecosystems contain sites with high tranquility-refuge value (refuge zones) which are very attractive for this Suidae thanks to the very dense vegetation (reed beds on the outskirts of the oases and the border areas of the wadis and chotts) and the almost impenetrability for man. When this species is present in abundance, it could cause severe ecological and socio-economic damage. The present work aims to analyze the spatial distribution of this species in the oases of southern Tunisia, namely the coastal oases of Gabès and the continental oases of Kébili, using GLMMs (generalized linear mixed models). In particular, it aims to evaluate the influence of certain landscape factors and vegetation on the occurrence of this harmful species. Our results suggest that the spatial occupancy of wild boar in Tunisian oases essentially depends on proximity to the nearest roads as a repelling factor as well as irrigation, the proportion of cereal cultivation and proximity to areas of refuge as attractive factors.Keywords: sus scrofa algirus, occurence, GLMM, oasis of southern tunisia
Procedia PDF Downloads 21255 Application of Medium High Hydrostatic Pressure in Preserving Textural Quality and Safety of Pineapple Compote
Authors: Nazim Uddin, Yohiko Nakaura, Kazutaka Yamamoto
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Compote (fruit in syrup) of pineapple (Ananas comosus L. Merrill) is expected to have a high market potential as one of convenient ready-to-eat (RTE) foods worldwide. High hydrostatic pressure (HHP) in combination with low temperature (LT) was applied to the processing of pineapple compote as well as medium HHP (MHHP) in combination with medium-high temperature (MHT) since both processes can enhance liquid impregnation and inactivate microbes. MHHP+MHT (55 or 65 °C) process, as well as the HHP+LT process, has successfully inactivated the microbes in the compote to a non-detectable level. Although the compotes processed by MHHP+MHT or HHP+LT have lost the fresh texture as in a similar manner as those processed solely by heat, it was indicated that the texture degradations by heat were suppressed under MHHP. Degassing process reduced the hardness, while calcium (Ca) contributed to be retained hardness in MHT and MHHP+MHT processes. Electrical impedance measurement supported the damage due to degassing and heat. The color, Brix, and appearance were not affected by the processing methods significantly. MHHP+MHT and HHP+LT processes may be applicable to produce high-quality, safe RTE pineapple compotes. Further studies on the optimization of packaging and storage condition will be indispensable for commercialization.Keywords: compote of pineapple, RTE, medium high hydrostatic pressure, postharvest loss, texture
Procedia PDF Downloads 1371254 In vitro Investigation of Genotoxic and Antigenotoxic Properties of Gunnera perpensa Roots Extracts
Authors: P. H. Mfengwana, S. S. Mashele, L. Verschaeve, R. Anthonissen, I. T. Manduna
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Gunnera perpensa is traditionally used mostly by women for the treatment of different gynaecological related conditions due to its proven uterine contractility effects. The uses of this plant include menstrual pain relief, treatment of infertility and promotion of easy labour. However, even though this plant species has been reported to possess numerous medicinal properties, to author’s best knowledge, its safety has not been investigated. Thus, this study was aimed at investigating the genotoxicity and antigenotoxicity of Gunnera perpensa aqueous, methanol and dichloromethane extracts. The in vitro toxicity of the plant extracts was assessed with the neutral red uptake (NRU) test. Genotoxic and antigenotoxic properties of Gunnera perpensa were investigated using high-throughput assays: bacterial Vitotox test and the alkaline comet assay with and without S9 activation on human C3A cells. Ethyl Methanesulfonate (EMS) and 4-nitroquinoline-oxide (4-NQO) were used as positive controls, respectively. All extracts showed toxicity in a dose-dependent manner; however, that does not mean they were all genotoxic. Methanol extract did show genotoxicity with S9 (metabolism) only at the highest concentration of 500 µg/ml due to increased DNA damage observed, however, no genotoxicity was observed from other concentrations. Therefore, the results show that Gunnera perpensa extracts are genotoxic and not safe for human use.Keywords: antigenotoxicity, comet test, genotoxicity, Gunnera perpensa, vitotox assay
Procedia PDF Downloads 1331253 Epileptic Seizures in Patients with Multiple Sclerosis
Authors: Anat Achiron
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Background: Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system in young adults. It involves the immune system attacking the protective covering of nerve fibers (myelin), leading to inflammation and damage. MS can result in various neurological symptoms, such as muscle weakness, coordination problems, and sensory disturbances. Seizures are not common in MS, and the frequency is estimated between 0.4 to 6.4% over the disease course. Objective: Investigate the frequency of seizures in individuals with multiple sclerosis and to identify associated risk factors. Methods: We evaluated the frequency of seizures in a large cohort of 5686 MS patients followed at the Sheba Multiple Sclerosis Center and studied associated risk factors and comorbidities. Our research was based on data collection using a cohort study design. We applied logistic regression analysis to assess the strength of associations. Results: We found that younger age at onset, longer disease duration, and prolonged time to immunomodulatory treatment initiation were associated with increased risk for seizures. Conclusions: Our findings suggest that seizures in people with MS are directly related to the demyelination process and not associated with other factors like medication side effects or comorbid conditions. Therefore, initiating immunomodulatory treatment early in the disease course could reduce not only disease activity but also decrease seizure risk.Keywords: epilepsy, seizures, multiple sclerosis, white matter, age
Procedia PDF Downloads 711252 Experimental and Numerical Investigations of Impact Response on High-Speed Train Windshield
Authors: Wen Ma, Yong Peng, Zhixiang Li
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Security journey is a vital focus on the field of Rail Transportation. Accidents caused by the damage of the high-speed train windshield have occurred many times and have given rise to terrible consequences. Train windshield consists of tempered glass and polyvinyl butyral (PVB) film. In this work, the quasi-static tests and the split Hopkinson pressure bar (SHPB) tests were carried out first to obtain the mechanical properties and constitutive model for the tempered glass and PVB film. These tests results revealed that stress and Young’s modulus of tempered glass were wake-sensitive to strain rate, but stress and Young’s modulus of PVB film were strong-sensitive to strain rate. Then impact experiment of the windshield was carried out to investigate dynamic response and failure characteristics of train windshield. In addition, a finite element model based on the combined finite element method was proposed to investigate fracture and fragmentation responses of train windshield under different-velocity impact. The results can be used for further design and optimization of the windshield for high-speed train application.Keywords: constitutive model, impact response, mechanism properties, PVB film, tempered glass
Procedia PDF Downloads 1461251 Logistics Process of Pineapple’s Leaves Product in Prachuapkhirikhan Province
Authors: Atcharawan Phenwansuk
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The product design is important to the development of SME towards the global, because it made to the quality product to react the needs of consumers and could reduces cost in the production, making it more profitable. As a results, the business are competition advantage for more marketing. It also enhance image of product and firms to build its own brand products to be acceptable. The product was designed should be shape, size, colorful, and direct of target consumers. This is method to add value products to get popular and effective, because the beauty is first satisfaction which come from main shape and color of the design product, but the product was designed need to hold data and law combination of shape and color between artistic theory and satisfaction of consumers together. The design must consider the safety of life and asset of consumers the most important. From to use of designed products should be to consider the cost savings, convenient distance, transportation, routes (land, water or air) of living space on transport (capacity, volume, width, length of the car, truck and container, etc). The packaging must be can to prevent not damage of the products. If products is more large , maybe to design new packaging, which can easily disassembled for make smaller package such as designing the assembly. Products must be packed in the container for size standard for save costs, as well as the buyer can make transport and assembly of products to fit easily on your own.Keywords: logistics process , pineapple’s leaves product, product design, satisfaction of consumers
Procedia PDF Downloads 3971250 Study and Modeling of Flood Watershed in Arid and Semi Arid Regions of Algeria
Authors: Belagoune Fares, Boutoutaou Djamel
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The study on floods in Algeria established by the National Agency of Water Resources (ANRH) shows that the country is confronted with the phenomenon of very destructive floods and floods especially in arid and semiarid regions. Flooding of rivers in these areas is less known. They are characterized by their sudden duration (rain showers, thunderstorm).The duration of the flood is of the order of minutes to hours. The human and material damage caused by these floods were still high. The study area encompasses three watersheds in semi-arid and arid south and Algeria. THERE are pools of Chott-Melghir (68,751 km2), highland Constantine-07 (9578 km2) and El Hodna-05 basin (25,843 km2). The total area of this zone is about 104,500km2.Studies of protection against floods and design studies of hydraulic structures (spillway, storm basin, etc.) require the raw data which is often unknown in several places particularly at ungauged wadis of these areas. This makes it very difficult to schedules and managers working in the field of hydraulic studies. The objective of this study and propose a methodology for determining flows in the absence of observations in the semi-arid and arid south eastern Algeria. The objective of the study is to propose a methodology for these areas of flood calculation for ungauged rivers.Keywords: flood, watershed, specific flow, coefficient of variation, arid
Procedia PDF Downloads 5061249 A Comparative Analysis of Machine Learning Techniques for PM10 Forecasting in Vilnius
Authors: Mina Adel Shokry Fahim, Jūratė Sužiedelytė Visockienė
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With the growing concern over air pollution (AP), it is clear that this has gained more prominence than ever before. The level of consciousness has increased and a sense of knowledge now has to be forwarded as a duty by those enlightened enough to disseminate it to others. This realisation often comes after an understanding of how poor air quality indices (AQI) damage human health. The study focuses on assessing air pollution prediction models specifically for Lithuania, addressing a substantial need for empirical research within the region. Concentrating on Vilnius, it specifically examines particulate matter concentrations 10 micrometers or less in diameter (PM10). Utilizing Gaussian Process Regression (GPR) and Regression Tree Ensemble, and Regression Tree methodologies, predictive forecasting models are validated and tested using hourly data from January 2020 to December 2022. The study explores the classification of AP data into anthropogenic and natural sources, the impact of AP on human health, and its connection to cardiovascular diseases. The study revealed varying levels of accuracy among the models, with GPR achieving the highest accuracy, indicated by an RMSE of 4.14 in validation and 3.89 in testing.Keywords: air pollution, anthropogenic and natural sources, machine learning, Gaussian process regression, tree ensemble, forecasting models, particulate matter
Procedia PDF Downloads 531248 Valorization of Waste and By-products for Protein Extraction and Functional Properties
Authors: Lorena Coelho, David Ramada, Catarina Nobre, Joaquim Gaião, Juliana Duarte
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The development of processes that allows the valorization of waste and by-products generated by industries is crucial to promote symbiotic relationships between different sectors and is mandatory to “close the loop” in the circular economy paradigm. In recent years, by-products and waste from agro-food and forestry sector have attracted attention due to their potential application and technical characteristics. The extraction of bio-based active compounds to be reused is in line with the circular bioeconomy concept trends, combining the use of renewable resources with the process’s circularity, aiming the waste reduction and encouraging reuse and recycling. Among different types of bio-based materials, which are being explored and can be extracted, proteins fractions are becoming an attractive new raw material. Within this context, BioTrace4Leather project, a collaboration between two Technological Centres – CeNTI and CTIC, and a company of Tanning and Finishing of Leather – Curtumes Aveneda, aims to develop innovative and biologically sustainable solutions for leather industry and accomplish the market circularity trends. Specifically, it aims to the valorisation of waste and by-products from the tannery industry through proteins extraction and the development of an innovative and biologically sustainable materials. The achieved results show that keratin, gelatine, and collagen fractions can be successfully extracted from hair and leather bovine waste. These products could be reintegrated into the industrial manufacturing process to attain innovative and functional textile and leather substrates. ACKNOWLEDGEMENT This work has been developed under BioTrace4Leather scope, a project co-funded by Operational Program for Competitiveness and Internationalization (COMPETE) of PORTUGAL2020, through the European Regional Development Fund (ERDF), under grant agreement Nº POCI-01-0247-FEDER-039867.Keywords: leather by-products, circular economy, sustainability, protein fractions
Procedia PDF Downloads 1581247 Challenges of Climate Change on Agricultural Productivity in Sub-Saharan Africa
Authors: Mohammed Sale Abubakar, Kabir Omar, Mohammed Umar Abba
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The effects of climate change continue to ravage globe upsetting or even overturning the entire communities in its wake. It is therefore on the front burner of most global issues affecting the world today. Hardly any field of endeavor has escaped the manifestation of its effects. The effects of climate change on agricultural productivity calls for intense study because of the nexus between agriculture, global food security and provision of employment for the teaming population in sub-saharan Africa. This paper examines current challenges of climate change on agricultural productivity in this region. This challenge indicated that both long and short-term change in climate bring unpleasant repercussion on agricultural productivity as they manifest in the vulnerability of industrial work force. The paper also focused on the impact of agriculture and bio-environmental engineering as a separate entity that will help to fight these major challenges facing humanity currently associated with negative effects of climate change such as scarcity of water, declining agricultural yields, desert encroachment, and damage of coastal structures. Finally, a suggestion was put forward as an effort that should be directed towards mitigating the negative effects of climate change on our environment.Keywords: climate change mitigation, desert encroachment, environment, global food security, greenhouse gases (GHGs)
Procedia PDF Downloads 3551246 Cost Effectiveness of Slit-Viscoelastic Dampers for Seismic Retrofit of Structures
Authors: Minsung Kim, Jinkoo Kim
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In order to reduce or eliminate seismic damage in structures, many researchers have investigated various energy dissipation devices. In this study, the seismic capacity and cost of a slit-viscoelastic seismic retrofit system composed of a steel slit plate and viscoelastic dampers connected in parallel are evaluated. The combination of the two different damping mechanisms is expected to produce enhanced seismic performance of the building. The analysis model of the system is first derived using various link elements in the nonlinear dynamic analysis software Perform 3D, and fragility curves of the structure retrofitted with the dampers are obtained using incremental dynamic analyses. The analysis results show that the displacement of the structure equipped with the hybrid dampers is smaller than that of the structure with slit dampers due to the enhanced self-centering capability of the system. It is also observed that the initial cost of hybrid system required for the seismic retrofit is smaller than that of the structure with viscoelastic dampers. Acknowledgement: This research was financially supported by the Ministry of Trade, Industry and Energy(MOTIE) and Korea Institute for Advancement of Technology(KIAT) through the International Cooperative R&D program(N043100016_Development of low-cost high-performance seismic energy dissipation devices using viscoelastic material).Keywords: damped cable systems, seismic retrofit, viscous dampers, self-centering
Procedia PDF Downloads 2671245 Exploring Urbanization-Induced Wetland Loss within the Greater Toronto Area from 2005 to 2015
Authors: Kaushika Vinotheeswaran
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The Greater Toronto Area (GTA), located in Ontario, Canada, is among the fastest-growing metropolitan areas in North America. Rapid urbanization within the GTA has led to increased imperviousness and surface runoff, contributing to wetland loss. Wetland cover and land cover data from the Southern Ontario Land Resource Information System were analyzed to characterize wetland loss to built-up areas and land conversions between 2005 and 2015, evaluating the extent of urbanization-induced wetland loss. Spatial analysis revealed a significant increase in the number of wetlands lost from 2005 to 2011 compared to the period from 2011 to 2015, with these losses attributed to increased urban expansions within the GTA. Non-wetland conversions, such as agricultural and impervious built-up uses to support urban expansions, played a significant role in wetland loss. Current approaches to wetland policy implementation and land-use planning strategies do not effectively identify or mitigate damage to wetlands in advance of development, resulting in significant wetland loss. Therefore, wetland conservation policies must be re-evaluated to address gaps in policy practice and focus on minimizing wetland loss.Keywords: wetland loss, urbanization, impervious, pervious, wetland conservation
Procedia PDF Downloads 701244 Cantilever Shoring Piles with Prestressing Strands: An Experimental Approach
Authors: Hani Mekdash, Lina Jaber, Yehia Temsah
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Underground space is becoming a necessity nowadays, especially in highly congested urban areas. Retaining underground excavations using shoring systems is essential in order to protect adjoining structures from potential damage or collapse. Reinforced Concrete Piles (RCP) supported by multiple rows of tie-back anchors are commonly used type of shoring systems in deep excavations. However, executing anchors can sometimes be challenging because they might illegally trespass neighboring properties or get obstructed by infrastructure and other underground facilities. A technique is proposed in this paper, and it involves the addition of eccentric high-strength steel strands to the RCP section through ducts without providing the pile with lateral supports. The strands are then vertically stressed externally on the pile cap using a hydraulic jack, creating a compressive strengthening force in the concrete section. An experimental study about the behavior of the shoring wall by pre-stressed piles is presented during the execution of an open excavation in an urban area (Beirut city) followed by numerical analysis using finite element software. Based on the experimental results, this technique is proven to be cost-effective and provides flexible and sustainable construction of shoring works.Keywords: deep excavation, prestressing, pre-stressed piles, shoring system
Procedia PDF Downloads 1171243 A Building Structure Health Monitoring DeviceBased on Cost Effective 1-Axis Accelerometers
Authors: Chih Hsing Lin, Wen-Ching Chen, Ssu-Ying Chen, Chih-Chyau Yang, Chien-Ming Wu, Chun-Ming Huang
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Critical structures such as buildings, bridges and dams require periodic inspections to ensure safe operation. The reliable inspection of structures can be achieved by combing temperature sensor and accelerometers. In this work, we propose a building structure health monitoring device (BSHMD) with using three 1-axis accelerometers, gateway, analog to digital converter (ADC), and data logger to monitoring the building structure. The proposed BSHMD achieves the features of low cost by using three 1-axis accelerometers with the data synchronization problem being solved, and easily installation and removal. Furthermore, we develop a packet acquisition program to receive the sensed data and then classify it based on time and date. Compared with 3-axis accelerometer, our proposed 1-axis accelerometers based device achieves 64.3% cost saving. Compared with previous structural monitoring device, the BSHMD achieves 89% area saving. Therefore, with using the proposed device, the realtime diagnosis system for building damage monitoring can be conducted effectively.Keywords: building structure health monitoring, cost effective, 1-axis accelerometers, real-time diagnosis
Procedia PDF Downloads 3691242 Roles of Lysine-63-Linked Ubiquitination in Cell Decision Fate between Cell Proliferation and Apoptosis
Authors: Chargui Abderrahman, Nehdi Afef , BelaïD Amine , Djerbi Nadir, Tauc Michel, Hofman Paul, Mograbi Baharia, El May MichèLe
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K63-linked ubiquitination — i.e. conjugation of a chain of ubiquitins (Ub) linked through lys63 — has emerged as a key mechanism regulating signalling transduction pathways. Although critical, very little information is currently available about how subversion of K63 ubiquitination might contribute to cancers and inflammatory diseases. The present study provides the first evidence that Cadmium (Cd), a widespread environmental carcinogen and toxicant, is a powerful activator of K63 ubiquitination. Indeed, Cd induces accumulation of K63 polyUb proteins. Importantly, Cd-induced ubiquitination does not stem on oxidative damage or proteasome impairment. Rather, we demonstrate that Cd not only activates K63 ubiquitination but also amplifies their accumulation by overloading the capacity of autophagy pathway. At molecular level, Cd-induced ubiquitination is correlated with stabilization of HIF-1 and the activation of NF-B, two transcription factors. Strikingly, prolonged cell exposure to high Cd concentrations induces an exaggerated K63 ubiquitination that fosters aggresome formation, thus precluding these proteins from interacting with their downstream nuclear targets. We therefore propose that the aberrant activation of K63 ubiquitination by the carcinogen Cadmium could promote cell proliferation and inflammation at low levels while high levels committed cell to death.Keywords: cadmium, environmental exposure, Lysine-63-ubiquitination, kidney, apoptosis, proliferation, autophagy
Procedia PDF Downloads 2091241 Structural Performance of Prefabricated Concrete and Reinforced Concrete Structural Walls under Blast Loads
Authors: S. Kamil Akin, Turgut Acikara
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In recent years the world and our country has experienced several explosion events occurred due to terrorist attacks and accidents. In these explosion events many people have lost their lives and many buildings have been damaged. If structures were designed taking the blast loads into account, these results may not have happened or the casualties would have been less. In this thesis analysis of the protection walls have been conducted to prevent the building damage from blast loads. These analyzes was carried out for two different types of wall, concrete and reinforced concrete. Analyses were carried out on four different thicknesses of each wall element. In each wall element the stresses and displacements of the exposed surface due to the detonation charge has been calculated. The limit shear stress and displacement of the wall element according to their material properties has been taken into account. As the result of the analyses the standoff distances and TNT equivalent amount has been determined. According to equivalent TNT amounts and standoff distances the structural response of the protective wall elements has been observed. These structural responses have been observed by ABAQUS finite element package. Explosion loads were brought into effect to the protective wall element models by using the ABAQUS / CONWEP.Keywords: blast loading, blast wave, TNT equivalent method, CONWEP, finite element analysis, detonation
Procedia PDF Downloads 4391240 Seismic Performance Evaluation of Structures with Hybrid Dampers Based on FEMA P-58 Methodology
Authors: Minsung Kim, Hyunkoo Kang, Jinkoo Kim
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In this study, a hybrid energy dissipation device is developed by combining a steel slit plate and friction pads to be used for seismic retrofit of structures, and its effectiveness is investigated by comparing the life cycle costs of the structure before and after the retrofit. The seismic energy dissipation capability of the dampers is confirmed by cyclic loading tests. The probabilities of reaching various damage states are obtained by fragility analysis, and the life cycle costs of the model structures are computed using the PACT (Performance Assessment Calculation Tool) program based on FEMA P-58 methodology. The fragility analysis shows that the probabilities of reaching limit states are minimized by the seismic retrofit with hybrid dampers and increasing column size. The seismic retrofit with increasing column size and hybrid dampers results in the lowest repair cost and shortest repair time. This research was supported by a grant (13AUDP-B066083-01) from Architecture & Urban Development Research Program funded by Ministry of Land, Infrastructure and Transport of Korean government.Keywords: FEMA P-58, friction dampers, life cycle cost, seismic retrofit
Procedia PDF Downloads 3371239 Analysis of Structure-Flow Interaction for Water Brake Mechanism
Authors: Murat Avci, Fatih Kosar, Ismail Yilmaz
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In this study, structure-flow interaction for water brake mechanism is studied with Abaqus CEL approach. The water brake mechanism is used for dynamic systems such as sled system on rail. For the achievement of these system tests, structure-flow interaction should be investigated in detail. This study is about a sled test of an aircraft subsystem which rises to supersonic speeds thanks to rocket engines. To decrease or to stop the thrusting rocket sleds, water brake mechanisms are used. Water brake mechanism provides the deceleration of the structures that have supersonic speeds. Therefore, structure-flow interaction may cause damage to the water brake mechanism. To verify all design revisions with system tests are so costly so that some decisions are taken in accordance with numerical methods. In this study, structure-flow interaction that belongs to water brake mechanism is solved with Abaqus CEL approach. Fluid and deformation on the structure behaviors are modeled at the same time thanks to CEL approach. Provided analysis results are corrected with the dynamic tests. Deformation zones seen in numerical analysis are also observed in dynamic tests. Finally, Johnson-Cook material model parameters used for this analysis are proven, and it is understood that these parameters can be used for dynamic analysis like water brake mechanism.Keywords: aircraft, rocket, structure-flow, supersonic
Procedia PDF Downloads 1581238 Environmental Impact Assessment of Ambient Particle Industrial Complex Upon Vegetation Near Settling at El-Fatyah,Libya
Authors: Ashraf M. S. Soliman, Mohsen Elhasadi
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The present study was undertaken to evaluate the impact of ambient particles emitted from an industrial complex located at El-Fatyah on growth, phytomass partitioning and accumulation, pigment content and nutrient uptake of two economically important crop species; barley (Hordeum vulgare L.Family: Poaceae) and broad bean (Vicia faba L. Family: Fabaceae) growing in the region. It was obvious from the present investigation that chlorophyll and carotenoid content showed significant responses to the industrial dust. Generally, the total pigment content of the two investigated crops in the two locations continually increased till the plant age reached 70 days after sowing then begins to decrease till the end of the growing season..The total uptake of N, P and K in the two studied species decreased in response to industrial dust in the study area compared to control location. In conclusion, barley and broad bean are very sensitive to air pollutants, and may consider as bioindicators for atmospheric pollution. Pollutants caused damage of their leaves, impair plant growth, hindered nutrient uptake and consequently limit primary productivity.Keywords: Effect of Industrial Complex on barley and broad bean
Procedia PDF Downloads 5361237 A Numerical Study on the Seismic Performance of Built-Up Battened Columns
Authors: Sophia C. Alih, Mohammadreza Vafaei, Farnoud Rahimi Mansour, Nur Hajarul Falahi Abdul Halim
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Built-up columns have been widely employed by practice engineers in the design and construction of buildings and bridges. However, failures have been observed in this type of columns in previous seismic events. This study analyses the performance of built-up columns with different configurations of battens when it is subjected to seismic loads. Four columns with different size of battens were simulated and subjected to three different intensities of axial load along with a lateral cyclic load. Results indicate that the size of battens influences significantly the seismic behavior of columns. Lower shear capacity of battens results in higher ultimate strength and ductility for built-up columns. It is observed that intensity of axial load has a significant effect on the ultimate strength of columns, but it is less influential on the yield strength. For a given drift value, the stress level in the centroid of smaller size battens is significantly more than that of larger size battens signifying damage concentration in battens rather than chords. It is concluded that design of battens for shear demand lower than code specified values only slightly reduces initial stiffness of columns; however, it improves seismic performance of battened columns.Keywords: battened column, built-up column, cyclic behavior, seismic design, steel column
Procedia PDF Downloads 2561236 Characterizing the Fracture Toughness Properties of Aluminum I-Rod Removed from National Research Universal Reactor
Authors: Michael Bach
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Extensive weld repair was carried out in 2009 after a leak was detected in the aluminum 5052 vessel of the National Research Universal (NRU) reactor. This was the second vessel installed since 1974. In support of the NRU vessel leak repair and fitness for service assessments, an estimate of property changes due to irradiation exposure is required to extend the service of the reactor until 2018. In order to fully evaluate the property changes in the vessel wall, an Iodine-125 rod (I rod) made from the same material and irradiated in the NRU reactor from 1974 1991, was retrieved and sectioned for microstructure characterization and mechanical testing. The different sections of the I rod were exposed to various levels of thermal neutron fluences from 0 to a maximum of 11.9 x 1022 n/cm2. The end of life thermal neutron fluence of the NRU vessel is estimated to be 2.2 x 1022 n/cm2 at 35 years of service. Tensile test and fracture toughness test was performed on the I-rod material at various axial locations. The changes in tensile properties were attributed primarily to the creation of finely dispersed Mg-Si precipitates that harden the material and reduced the ductility. Despite having a reduction in fracture toughness, the NRU vessel is still operation at the current fluence levels.Keywords: aluminum alloy, fitness-for-service assessment , fracutre toughness, nuclear reactor, precipitate strengthening, radiation damage, tensile strength
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