Search results for: pile load test.

Authors: Young-Jun You, Ki-Tae Park, Kyu-Wan Lee

Abstract:

Since prestressed concrete members rely on the tensile strength of the prestressing strands to resist loads, loss of even few them could result catastrophic. Therefore, it is important to measure present residual prestress force. Although there are some techniques for obtaining present prestress force, some problems still remain. One method is to install load cell in front of anchor head but this may increase cost. Load cell is a transducer using the elastic material property. Anchor head is also an elastic material and this might result in monitoring monitor present prestress force. Features of fiber optic sensor such as small size, great sensitivity, high durability can assign sensing function to anchor head. This paper presents the concept of smart anchor head which acts as load cell and experiment for the applicability of it. Test results showed the smart anchor head worked good and strong linear relationship between load and response.

Keywords: SHM, prestress force, anchor head, fiber optic sensor

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Authors: Heung Seok Chae, Jaegeol Park

Abstract:

Recently, there have been an increasing interest in RFID system and RFID systems have been applied to various applications. Load balancing is a fundamental technique for providing scalability of systems by moving workload from overloaded nodes to under-loaded nodes. This paper presents an approach to adaptive load balancing for RFID middlewares. Workloads of RFID middlewares can have a considerable variation according to the location of the connected RFID readers and can abruptly change at a particular instance. The proposed approach considers those characteristics of RFID middle- wares to provide an efficient load balancing.

Keywords: RFID middleware, Adaptive load balancing.

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Authors: S.A. Alqallaf, S.A. Al-Mawsawi, A. Haider

Abstract:

In order to evaluate the performance of a unified power flow controller (UPFC), mathematical models for steady state and dynamic analysis are to be developed. The steady state model is mainly concerned with the incorporation of the UPFC in load flow studies. Several load flow models for UPFC have been introduced in literature, and one of the most reliable models is the decoupled UPFC model. In spite of UPFC decoupled load flow model simplicity, it is more robust compared to other UPFC load flow models and it contains unique capabilities. Some shortcoming such as additional set of nonlinear equations are to be solved separately after the load flow solution is obtained. The aim of this study is to investigate the different control strategies that can be realized in the decoupled load flow model (individual control and combined control), and the impact of the location of the UPFC in the network on its control parameters.

Keywords: UPFC, Decoupled model, Load flow.

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Authors: Mandla T. Nene, Edgar.Jembere, Matthew O. Adigun, Themba Shezi, Siyabonga S. Cebekhulu

Abstract:

The drastic increase in the usage of SMS technology has led service providers to seek for a solution that enable users of mobile devices to access services through SMSs. This has resulted in the proposal of solutions towards SMS-based service invocation in service oriented environments. However, the dynamic nature of service-oriented environments coupled with sudden load peaks generated by service request, poses performance challenges to infrastructures for supporting SMS-based service invocation. To address this problem we adopt load balancing techniques. A load balancing model with adaptive load balancing and load monitoring mechanisms as its key constructs is proposed. The load balancing model then led to realization of Least Loaded Load Balancing Framework (LLLBF). Evaluation of LLLBF benchmarked with round robin (RR) scheme on the queuing approach showed LLLBF outperformed RR in terms of response time and throughput. However, LLLBF achieved better result in the cost of high processing power.

Keywords: SMS (Short Message Service), LLLBF (Least Loaded Load Balancing Framework), Service Oriented Computing (SOC).

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Authors: Ali Fadhil Naser, Wang Zonglin

Abstract:

The main objectives of this study are to inspect and identify any damage of jaimusi highway prestressed concrete bridge after repair and strengthening of damaged structural members and to evaluate the performance of the bridge structural members by adopting static load test. Inspection program after repair and strengthening includes identifying and evaluating the structural members of bridge such as T-shape cantilever structure, hanging beams, corbels, external tendons, anchor beams, sticking steel plate, and piers. The results of inspection show that the overall state of the bridge structural member after repair and strengthening is good. The results of rebound test of concrete strength show that the average strength of concrete is 46.31Mpa. Whereas, the average value of concrete strength of anchor beam is 49.82Mpa. According to the results of static load test, the experimental values are less than theoretical values of internal forces, deflection, and strain, indicating that the stiffness of the experimental structure, overall deformation and integrity satisfy the designed standard and the working performance is good, and the undertaking capacity has a certain surplus. There is not visible change in the length and width of cracks and there are not new cracks under experimental load.

Keywords: Jiamusi Bridge, Damage inspection, deflection, strain.

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Authors: T. Y. Huang, B. Z. Wang, S. C. Lin, S. Y. Hsu

Abstract:

A CFD software was employed to analyze the characteristics of the flat round porous aerostatic bearings. The effects of gap between the bearing and the guide way and the porosity of the porous material on the load capacity of the bearing were studied. The adequacy of the simulation model and the approach was verified. From the parametric study, it is found that the depth of the flow path does not influence the load capacity of the bearing; the load capacity of the bearing will decrease if the thickness of the porous material increases or the porous material protrudes above the bearing housing; the variation of the chamfer at the edge of the bearing does not affect the bearing load capacity. For a bearing with an air gap of 5μm and a porosity of 0.1, the average load capacity and the pressure distribution of the bearing are nearly unchanged no matter the bearing moves at a constant or a varying speed.

Keywords: Aerostatic bearing, Load capacity, Porosity, Porous material.

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Authors: Aleš Florian, Lenka Ševelová

Abstract:

Low volume roads are widely used all over the world. To improve their quality the computer simulation of their behavior is proposed. The FEM model enables to determine stress and displacement conditions in the pavement and/or also in the particular material layers. Different variants of pavement layers, material used, humidity as well as loading conditions can be studied. Among others, the input information about material properties of individual layers made from recycled materials is crucial for obtaining results as exact as possible. For this purpose the cyclic-load triaxial test machine testing of cyclic-load performance of materials is a promising test method. The test is able to simulate the real traffic loading on particular materials taking into account the changes in the horizontal stress conditions produced in particular layers by crossings of vehicles. Also the test specimen can be prepared with different amount of water. Thus modulus of elasticity (Young modulus) of different materials including recycled ones can be measured under the different conditions of horizontal and vertical stresses as well as under the different humidity conditions. Using the proposed testing procedure the modulus of elasticity of recycled materials used in the newly built low volume road is obtained under different stress and humidity conditions set to standard, dry and fully saturated level. Obtained values of modulus of elasticity are used in FEA.

Keywords: FEA, FEM, geotechnical materials, low volume roads, pavement, triaxial test, Young modulus.

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Authors: N. Mungkung, S. Wongcharoen, C. Sukkongwari, Somchai Arunrungrasmi

Abstract:

This study examines the design and construction of AC Electronics load surge protection in order to carry electric surge load arisen from faults in low voltage electricity system (single phase/220V) by using the principle of electronics load clamping voltage during induction period so that electric voltage could go through to safe load and continue to work. The qualification of the designed device could prevent both transient over voltage and voltage swell. Both will work in cooperation, resulting in the ability to improve and modify the quality of electrical power in Thailand electricity distribution system more effective than the past and help increase the lifetime of electric appliances, electric devices, and electricity protection equipments.

Keywords: Electronics Load, Transient Over Voltage, Voltage Swell.

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Authors: P. S. Bhowmik, D. V. Rajan, S. P. Bose

Abstract:

The load flow study in a power system constitutes a study of paramount importance. The study reveals the electrical performance and power flows (real and reactive) for specified condition when the system is operating under steady state. This paper gives an overview of different techniques used for load flow study under different specified conditions.

Keywords: Load Flow Studies, Y-matrix and Z-matrix iteration, Newton-Raphson method, Fast Decoupled method, Fuzzy logic, Artificial Neural Network.

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Authors: H. Aldousari, T. Buchacher, N. M. Spyrou

Abstract:

Cerium-doped lanthanum bromide LaBr3:Ce(5%) crystals are considered to be one of the most advanced scintillator materials used in PET scanning, combining a high light yield, fast decay time and excellent energy resolution. Apart from the correct choice of scintillator, it is also important to optimise the detector geometry, not least in terms of source-to-detector distance in order to obtain reliable measurements and efficiency. In this study a commercially available 25 mm x 25 mm BrilLanCeTM 380 LaBr3: Ce (5%) detector was characterised in terms of its efficiency at varying source-to-detector distances. Gamma-ray spectra of 22Na, 60Co, and 137Cs were separately acquired at distances of 5, 10, 15, and 20cm. As a result of the change in solid angle subtended by the detector, the geometric efficiency reduced in efficiency with increasing distance. High efficiencies at low distances can cause pulse pile-up when subsequent photons are detected before previously detected events have decayed. To reduce this systematic error the source-to-detector distance should be balanced between efficiency and pulse pile-up suppression as otherwise pile-up corrections would need to be necessary at short distances. In addition to the experimental measurements Monte Carlo simulations have been carried out for the same setup, allowing a comparison of results. The advantages and disadvantages of each approach have been highlighted.

Keywords: BrilLanCeTM380 LaBr3:Ce(5%), Coincidence summing, GATE simulation, Geometric efficiency

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Authors: Eman Alzahrani, Hala M. Abo-Dief, Ashraf T. Mohamed

Abstract:

The present work is aimed at examining carbon steel oil pipelines corrosion using three natural extracts (Eruca Sativa, Rosell and Mango peels) that are used as inhibitors of different concentrations ranging from 0.05-0.1wt. %. Two sulphur compounds are used as corrosion mediums. Weight loss method was used for measuring the corrosion rate of the carbon steel specimens immersed in technical white oil at 100ºC at various time intervals in absence and presence of the two sulphur compounds. The corroded specimens are examined using the chemical wear test, scratch test and hardness test. The scratch test is carried out using scratch loads from 0.5 Kg to 2.0 Kg. The scratch width is obtained at various scratch load and test conditions. The Brinell hardness test is carried out and investigated for both corroded and inhibited specimens. The results showed that three natural extracts can be used as environmentally friendly corrosion inhibitors.

Keywords: Inhibition, natural extract, pipelines corrosion, sulphur compounds.

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Authors: Bachir Chemani, Rachid Halfaoui

Abstract:

The aim of study was to evaluate pressure distribution characteristics of the elastic textile bandages using two instrumental techniques: a prototype Instrument and a load Transference. The prototype instrument which simulates shape of real leg has pressure sensors which measure bandage pressure. Using this instrument, the results show that elastic textile bandages presents different pressure distribution characteristics and none produces a uniform distribution around lower limb.

The load transference test procedure is used to determine whether a relationship exists between elastic textile bandage structure and pressure distribution characteristics. The test procedure assesses degree of load, directly transferred through a textile when loads series are applied to bandaging surface. A range of weave fabrics was produced using needle weaving machine and a sewing technique. A textile bandage was developed with optimal characteristics far superior pressure distribution than other bandages. From results, we find that theoretical pressure is not consistent exactly with practical pressure. It is important in this study to make a practical application for specialized nurses in order to verify the results and draw useful conclusions for predicting the use of this type of elastic band.

Keywords: Textile, cotton, pressure, venous ulcers, elastic.

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Authors: Jagadish H. Pujar

Abstract:

Fuzzy Load forecasting plays a paramount role in the operation and management of power systems. Accurate estimation of future power demands for various lead times facilitates the task of generating power reliably and economically. The forecasting of future loads for a relatively large lead time (months to few years) is studied here (long term load forecasting). Among the various techniques used in forecasting load, artificial intelligence techniques provide greater accuracy to the forecasts as compared to conventional techniques. Fuzzy Logic, a very robust artificial intelligent technique, is described in this paper to forecast load on long term basis. The paper gives a general algorithm to forecast long term load. The algorithm is an Extension of Short term load forecasting method to Long term load forecasting and concentrates not only on the forecast values of load but also on the errors incorporated into the forecast. Hence, by correcting the errors in the forecast, forecasts with very high accuracy have been achieved. The algorithm, in the paper, is demonstrated with the help of data collected for residential sector (LT2 (a) type load: Domestic consumers). Load, is determined for three consecutive years (from April-06 to March-09) in order to demonstrate the efficiency of the algorithm and to forecast for the next two years (from April-09 to March-11).

Keywords: Fuzzy Logic Control (FLC), Data DependantFactors(DDF), Model Dependent Factors(MDF), StatisticalError(SE), Short Term Load Forecasting (STLF), MiscellaneousError(ME).

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Authors: T. Karech A. Noui, T. Bouzid

Abstract:

This article presents a comparative study by numerical analysis of the behavior of reinforcements of clayey soils by flexible columns (stone columns) and rigid columns (piles). The numerical simulation was carried out in 3D for an assembly of foundation, columns and a pile of a bridge. Particular attention has been paid to take into account the installation of the columns. Indeed, in practice, due to the compaction of the column, the soil around it sustains a lateral expansion and the horizontal stresses are increased. This lateral expansion of the column can be simulated numerically. This work represents a comparative study of the interaction between the soil on one side, and the two types of reinforcement on the other side, and their influence on the behavior of the soil and of the pile of a bridge.

Keywords: Piles, stone columns, interaction, foundation, settlement, consolidation.

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Authors: Y. H. Mugahed Amran, Raizal S. M. Rashid, Farzad Hejazi, Nor Azizi Safiee, A. A. Abang Ali

Abstract:

Experimental and analytical studies were accomplished to examine the structural behavior of precast foamed concrete sandwich panel (PFCSP) under vertical in-plane shear load. PFCSP full-scale specimens with total number of six were developed with varying heights to study an important parameter slenderness ratio (H/t). The production technique of PFCSP and the procedure of test setup were described. The results obtained from the experimental tests were analysed in the context of in-plane shear strength capacity, load-deflection profile, load-strain relationship, slenderness ratio, shear cracking patterns and mode of failure. Analytical study of finite element analysis was implemented and the theoretical calculations of the ultimate in-plane shear strengths using the adopted ACI318 equation for reinforced concrete wall were determined aimed at predicting the in-plane shear strength of PFCSP. The decrease in slenderness ratio from 24 to 14 showed an increase of 26.51% and 21.91% on the ultimate in-plane shear strength capacity as obtained experimentally and in FEA models, respectively. The experimental test results, FEA models data and theoretical calculation values were compared and provided a significant agreement with high degree of accuracy. Therefore, on the basis of the results obtained, PFCSP wall has the potential use as an alternative to the conventional load-bearing wall system.

Keywords: Deflection profiles, foamed concrete, load-strain relationships, precast foamed concrete sandwich panel, slenderness ratio, vertical in-plane shear strength capacity.

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Authors: Jungbhin You, Taekyun Kim, Jongho Park, Sungnam Hong, Sun-Kyu Park

Abstract:

Reinforced concrete has been mainly used in construction field because of excellent durability. However, it may lead to reduction of durability and safety due to corrosion of reinforcement steels according to damage of concrete surface. Recently, research of textile is ongoing to complement weakness of reinforced concrete. In previous research, only experiment of longitudinal length were performed. Therefore, in order to investigate the adhesion performance according to the lattice shape and the embedded length, the pull-out test was performed on the roving with parameter of the number of lateral reinforcement, the lateral reinforcement length and the lateral reinforcement spacing. As a result, the number of lateral reinforcement and the lateral reinforcement length did not significantly affect the load variation depending on the adhesion performance, and only the load analysis results according to the reinforcement spacing are affected.

Keywords: Adhesion performance, lateral reinforcement, pull-out test, textile.

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Authors: Smarajit Ghosh , Karma Sonam Sherpa

Abstract:

This paper reports a new and accurate method for load-flow solution of radial distribution networks with minimum data preparation. The node and branch numbering need not to be sequential like other available methods. The proposed method does not need sending-node, receiving-node and branch numbers if these are sequential. The proposed method uses the simple equation to compute the voltage magnitude and has the capability to handle composite load modelling. The proposed method uses the set of nodes of feeder, lateral(s) and sub lateral(s). The effectiveness of the proposed method is compared with other methods using two examples. The detailed load-flow results for different kind of load-modellings are also presented.

Keywords: Load−flow, Feeder, Lateral, Power, Voltage, Composite, Exponential

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Authors: P. Sateesh Kumar , S. Ramachandram

Abstract:

Genetic Zone Routing Protocol (GZRP) is a new hybrid routing protocol for MANETs which is an extension of ZRP by using Genetic Algorithm (GA). GZRP uses GA on IERP and BRP parts of ZRP to provide a limited set of alternative routes to the destination in order to load balance the network and robustness during node/link failure during the route discovery process. GZRP is studied for its performance compared to ZRP in many folds like scalability for packet delivery and proved with improved results. This paper presents the results of the effect of load balancing on GZRP. The results show that GZRP outperforms ZRP while balancing the load.

Keywords: MANET, routing, ZRP, Genetic algorithm, GZRP, load balancing

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Authors: M. Sedighizadeh, A. Rezazadeh

Abstract:

Based on the component approach, three kinds of dynamic load models, including a single –motor model, a two-motor model and composite load model have been developed for the stability studies of Khuzestan power system. The study results are presented in this paper. Voltage instability is a dynamic phenomenon and therefore requires dynamic representation of the power system components. Industrial loads contain a large fraction of induction machines. Several models of different complexity are available for the description investigations. This study evaluates the dynamic performances of several dynamic load models in combination with the dynamics of a load changing transformer. Case study is steel industrial substation in Khuzestan power systems.

Keywords: Dynamic load, modeling, Voltage Stability.

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Authors: Anas M. Fares

Abstract:

The using of finite element programs in analyzing and designing buildings are becoming very popular, but there are many engineers still using the tributary area method (TAM) in designing the structural members such as columns. This study is an attempt to investigate the accuracy of the TAM results with different load condition (gravity and lateral load), different floors numbers, and different columns stiffness's. To conduct this study, linear elastic analysis in ETABS program is used. The results from finite element method are compared to those obtained from TAM. According to the analysis of the data obtained, it can be seen that there is significance difference between the real load carried by columns and the load which is calculated by using the TAM. Thus, using 3-D models are the best choice to calculate the real load effected on columns and design these columns according to this load.

Keywords: Tributary area method, finite element method, ETABS, lateral load, axial loads, reinforced concrete, stiffness, multi-floor buildings.

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Authors: F. Vallée, J-F. Toubeau, Z. De Grève, J. Lobry

Abstract:

When evaluating the capacity of a generation park to cover the load in transmission systems, traditional Loss of Load Expectation (LOLE) and Expected Energy not Served (EENS) indices can be used. If those indices allow computing the annual duration and severity of load non covering situations, they do not take into account the fact that the load excess is generally shifted from one penury state (hour or quarter of an hour) to the following one. In this paper, a sequential Monte Carlo framework is introduced in order to compute adjusted LOLE and EENS indices. Practically, those adapted indices permit to consider the effect of load excess transfer on the global adequacy of a generation park, providing thus a more accurate evaluation of this quantity.

Keywords: Expected Energy not Served, Loss of Load Expectation, Monte Carlo simulation, reliability, wind generation.

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Authors: Brice Nya, Detlef Schulz

Abstract:

Any use of energy in industrial productive activities is combined with various environment impacts. Withintransportation, this fact was not only found among land transport, railways and maritime transport, but also in the air transport industry. An effective climate protection requires strategies and measures for reducing all greenhouses gas emissions, in particular carbon dioxide, and must take into account the economic, ecologic and social aspects. It seem simperative now to develop and manufacture environmentally friendly products and systems, to reduce consumption and use less resource, and to save energy and power. Today-sproducts could better serve these requirements taking into account the integration of a power management system into the electrical power system.This paper gives an overview of an approach ofpower management with load prioritization in modernaircraft. Load dimensioning and load management strategies on current civil aircraft will be presented and used as a basis for the proposed approach.

Keywords: Load management, power management, electrical load analysis, flight mission, power load profile.

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Authors: A.Gjukaj, G.Kabashi, G.Pula, N.Avdiu, B.Prebreza

Abstract:

This paper discusses aspects of re-design of loadshedding schemes with respect to actual developments in the Kosovo power system. Load-shedding is a type of emergency control that is designed to ensure system stability by reducing power system load to match the power generation supply. This paper presents a new adaptive load-shedding scheme that provides emergency protection against excess frequency decline, in cases when the Kosovo power system might be disconnected from the regional transmission network. The proposed load-shedding scheme uses the local frequency rate information to adapt the load-shedding pattern to suit the size and location of the occurring disturbance. The proposed scheme is tested in a software simulation on a large scale PSS/E model which represents nine power system areas of Southeast Europe including the Kosovo power system.

Keywords: About Load Shedding, Power System Transient, PSS/E Dynamic Simulation, Under-frequency Protection

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Authors: D. P. Sharma, A. Chaturvedi, G.Purohit , R.Shivarudraswamy

Abstract:

In today scenario, to meet enhanced demand imposed by domestic, commercial and industrial consumers, various operational & control activities of Radial Distribution Network (RDN) requires a focused attention. Irrespective of sub-domains research aspects of RDN like network reconfiguration, reactive power compensation and economic load scheduling etc, network performance parameters are usually estimated by an iterative process and is commonly known as load (power) flow algorithm. In this paper, a simple mechanism is presented to implement the load flow analysis (LFA) algorithm. The reported algorithm utilizes graph theory principles and is tested on a 69- bus RDN.

Keywords: Radial Distribution network, Graph, Load-flow, Array.

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Authors: Ajay Shekhar Pandey, D. Singh, S. K. Sinha

Abstract:

A clustering based technique has been developed and implemented for Short Term Load Forecasting, in this article. Formulation has been done using Mean Absolute Percentage Error (MAPE) as an objective function. Data Matrix and cluster size are optimization variables. Model designed, uses two temperature variables. This is compared with six input Radial Basis Function Neural Network (RBFNN) and Fuzzy Inference Neural Network (FINN) for the data of the same system, for same time period. The fuzzy inference system has the network structure and the training procedure of a neural network which initially creates a rule base from existing historical load data. It is observed that the proposed clustering based model is giving better forecasting accuracy as compared to the other two methods. Test results also indicate that the RBFNN can forecast future loads with accuracy comparable to that of proposed method, where as the training time required in the case of FINN is much less.

Keywords: Load forecasting, clustering, fuzzy inference.

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Authors: M Ahmadigorji, A. Abbaspour, A Rajabi-Ghahnavieh, M. Fotuhi- Firuzabad

Abstract:

DG application has received increasing attention during recent years. The impact of DG on various aspects of distribution system operation, such as reliability and energy loss, depend highly on DG location in distribution feeder. Optimal DG placement is an important subject which has not been fully discussed yet. This paper presents an optimization method to determine optimal DG placement, based on a cost/worth analysis approach. This method considers technical and economical factors such as energy loss, load point reliability indices and DG costs, and particularly, portability of DG. The proposed method is applied to a test system and the impacts of different parameters such as load growth rate and load forecast uncertainty (LFU) on optimum DG location are studied.

Keywords: Distributed generation, optimal placement, cost/worthanalysis, customer interruption cost, Dynamic programming

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Authors: Omid Borazjani, Mahmoud Roosta, Khodakhast Isapour, Ali Reza Rajabi

Abstract:

This paper presents an application of Artificial Neural Network (ANN) algorithm for improving power system voltage stability. The training data is obtained by solving several normal and abnormal conditions using the Linear Programming technique. The selected objective function gives minimum deviation of the reactive power control variables, which leads to the maximization of minimum Eigen value of load flow Jacobian. The considered reactive power control variables are switchable VAR compensators, OLTC transformers and excitation of generators. The method has been implemented on a modified IEEE 30-bus test system. The results obtain from the test clearly show that the trained neural network is capable of improving the voltage stability in power system with a high level of precision and speed.

Keywords: Artificial Neural Network (ANN), Load Flow, Voltage Stability, Power Systems.

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Authors: Djilani Kobibi Youcef Islam, Hadjeri Samir, Djehaf Mohamed Abdeldjalil

Abstract:

The Flexible AC Transmission System (FACTS) technology is a new advanced solution that increases the reliability and provides more flexibility, controllability, and stability of a power system. The Unified Power Flow Controller (UPFC), as the most versatile FACTS device for regulating power flow, is able to control respectively transmission line real power, reactive power, and node voltage. The main purpose of this paper is to analyze the effect of the UPFC on the load flow, the power losses, and the voltage stability using NEPLAN software modules, Newton-Raphson load flow is used for the power flow analysis and the modal analysis is used for the study of the voltage stability. The simulation was carried out on the IEEE 14-bus test system.

Keywords: FACTS, load flow, modal analysis, UPFC, voltage stability.

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Authors: O. A. Rahmeh, P. Johnson, S. Lehmann

Abstract:

Grid networks provide the ability to perform higher throughput computing by taking advantage of many networked computer-s resources to solve large-scale computation problems. As the popularity of the Grid networks has increased, there is a need to efficiently distribute the load among the resources accessible on the network. In this paper, we present a stochastic network system that gives a distributed load-balancing scheme by generating almost regular networks. This network system is self-organized and depends only on local information for load distribution and resource discovery. The in-degree of each node is refers to its free resources, and job assignment and resource discovery processes required for load balancing is accomplished by using fitted random sampling. Simulation results show that the generated network system provides an effective, scalable, and reliable load-balancing scheme for the distributed resources accessible on Grid networks.

Keywords: Complex networks, grid networks, load-balancing, random sampling.

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Authors: Siobhan O’Shea, Sangeetha Vijaysri Nair, Hee Cheol Kim, Charles Thomas Nugent, Cheuk Yan William Tong, Sam Douthwaite, Andrew Worlock

Abstract:

The Aptima® HIV-1 Quant Dx Assay is a fully automated assay on the Panther system. It is based on Transcription- Mediated Amplification and real time detection technologies. This assay is intended for monitoring HIV-1 viral load in plasma specimens and for the detection of HIV-1 in plasma and serum specimens. Nine-hundred and seventy nine specimens selected at random from routine testing at St Thomas’ Hospital, London were anonymised and used to compare the performance of the Aptima HIV-1 Quant Dx assay and Roche COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0. Two-hundred and thirty four specimens gave quantitative HIV-1 viral load results in both assays. The quantitative results reported by the Aptima Assay were comparable to those reported by the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, v2.0 with a linear regression slope of 1.04 and an intercept on -0.097. The Aptima assay detected HIV-1 in more samples than the COBAS assay. This was not due to lack of specificity of the Aptima assay because this assay gave 99.83% specificity on testing plasma specimens from 600 HIV-1 negative individuals. To understand the reason for this higher detection rate a side-by-side comparison of low level panels made from the HIV-1 3rd international standard (NIBSC10/152) and clinical samples of various subtypes were tested in both assays. The Aptima assay was more sensitive than the COBAS assay. The good sensitivity, specificity and agreement with other commercial assays make the HIV-1 Quant Dx Assay appropriate for both viral load monitoring and detection of HIV-1 infections.

Keywords: HIV viral load, Aptima, Roche, Panther system.

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