Search results for: cell area.

Authors: P. Varzakas

Abstract:

In this paper, the problem of estimating the optimal radio capacity of a single-cell spread spectrum (SS) multiple-inputmultiple- output (MIMO) system operating in a Rayleigh fading environment is examined. The optimisation between the radio capacity and the theoretically achievable average channel capacity (in the sense of information theory) per user of a MIMO single-cell SS system operating in a Rayleigh fading environment is presented. Then, the spectral efficiency is estimated in terms of the achievable average channel capacity per user, during the operation over a broadcast time-varying link, and leads to a simple novel-closed form expression for the optimal radio capacity value based on the maximization of the achieved spectral efficiency. Numerical results are presented to illustrate the proposed analysis.

Keywords: Channel capacity, MIMO systems, Radio capacity, Rayleigh fading, Spectral efficiency.

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Authors: Mehdi Modabberifar, Milad Roodi, Ehsan Souri

Abstract:

In recent years, honeycomb fiber reinforced plastic (FRP) sandwich panels have been increasingly used in various industries. Low weight, low price and high mechanical strength are the benefits of these structures. However, their mechanical properties and behavior have not been fully explored. The objective of this study is to conduct a combined numerical-statistical investigation of honeycomb FRP sandwich beams subject to torsion load. In this paper, the effect of geometric parameters of sandwich panel on maximum shear strain in both face and core and angle of torsion in a honeycomb FRP sandwich structures in torsion is investigated. The effect of Parameters including core thickness, face skin thickness, cell shape, cell size, and cell thickness on mechanical behavior of the structure were numerically investigated. Main effects of factors were considered in this paper and regression equations were derived. Taguchi method was employed as experimental design and an optimum parameter combination for the maximum structure stiffness has been obtained. The results showed that cell size and face skin thickness have the most significant impacts on torsion angle, maximum shear strain in face and core.

Keywords: Finite element, honeycomb FRP sandwich panel, torsion, civil engineering.

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Authors: R. Kandiah, K. Miyamoto

Abstract:

In Sri Lanka, the Jaffna area is a high drought affected area and depends mainly on groundwater aquifers for water needs. Water for daily activities is extracted from wells. As households manually extract water from the wells, it is not drawn from mid evening to early morning. The water inflow at night provides the maximum water level that decreases during the daytime due to extraction. The storage volume of water in wells is limited or at its lowest level during the dry season. This study analyzes the domestic water budget during the dry season in the Jaffna area. In order to evaluate the water inflow rate into wells, storage volume and extraction volume from wells over time, water pressure is measured at the bottom of three wells, which are located in coastal area denoted as well A, in nonspecific area denoted as well B, and agricultural area denoted as well C. The water quality at the wells A, B, and C, are mostly fresh, modest fresh, and saline respectively. From the monitoring, we can find that the daily inflow amount of water into the wells and daily water extraction depend on each other, that is, higher extraction yields higher inflow. And, in the dry season, the daily inflow volume and the daily extraction volume of each well are almost in balance.

Keywords: Domestic water, water balance, water budget, ground water, shallow well.

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Authors: Fatih Özogul, Nurten Toy, Yesim Özogul

Abstract:

The influences of cell-free solutions (CFSs) of lactic acid bacteria (LAB) on cadaverine and other biogenic amines production by Listeria monocytogenes and Staphylococcus aureus were investigated in lysine decarboxylase broth (LDB) using HPLC. Cell free solutions were prepared from Lactococcus lactis subsp. lactis, Leuconostoc mesenteroides subsp. cremoris, Pediococcus acidilactici and Streptococcus thermophiles. Two different concentrations that were 50% and 25% CFS and the control without CFSs were prepared. Significant variations on biogenic amine production were observed in the presence of L. monocytogenes and S. aureus (P < 0.05). The function of CFS on biogenic amine production by foodborne pathogens varied depending on strains and specific amine. Cadaverine formation by L. monocytogenes and S. aureus in control were 500.9 and 948.1 mg/L, respectively while the CFSs of LAB induced 4-fold lower cadaverine production by L. monocytogenes and 7-fold lower cadaverine production by S. aureus. The CFSs resulted in strong decreases in cadaverine and putrescine production by L. monocytogenes and S. aureus, although remarkable increases were observed for histamine, spermidine, spermine, serotonin, dopamine, tyramine and agmatine in the presence of LAB in lysine decarboxylase broth.

Keywords: Cell-free solution, lactic acid bacteria, cadaverine, food borne-pathogen.

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Authors: E. Bene

Abstract:

Our sowing date experiment took place in the Demonstration Garden of Institution of Plant Sciences, Centre for Agricultural Sciences of University of Debrecen, in 2012-2014. The paper contains data of test year 2014. Our purpose, besides several other examinations, was to observe how sowing date influences the leaf area index and the activity of photosynthesis of maize hybrids, and how those factors affect fruiting. In the experiment we monitored the change of the leaf area index and the photosynthesis of hybrids with four different growing seasons. The results obtained confirm that not only the environmental and agricultural factors in the growing season have effect on the yield, but also other factors like the leaf area index and the photosynthesis are determinative parameters, and all those factors together, modifying the effects of each other, develop average yields.

Keywords: Sowing date, hybrid, leaf area index, photosynthetic capacity.

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Authors: S. H. Borghei, E. Teymourian, M. Mobin, G. M. Komaki, S. Sheikh

Abstract:

Imperialist Competitive Algorithm (ICA) is a recent meta-heuristic method that is inspired by the social evolutions for solving NP-Hard problems. The ICA is a population-based algorithm which has achieved a great performance in comparison to other metaheuristics. This study is about developing enhanced ICA approach to solve the Cell Formation Problem (CFP) using sequence data. In addition to the conventional ICA, an enhanced version of ICA, namely EICA, applies local search techniques to add more intensification aptitude and embed the features of exploration and intensification more successfully. Suitable performance measures are used to compare the proposed algorithms with some other powerful solution approaches in the literature. In the same way, for checking the proficiency of algorithms, forty test problems are presented. Five benchmark problems have sequence data, and other ones are based on 0-1 matrices modified to sequence based problems. Computational results elucidate the efficiency of the EICA in solving CFP problems.

Keywords: Cell formation problem, Group technology, Imperialist competitive algorithm, Sequence data.

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Authors: Murad A, Baker H, Mahmoud S, Gabr A

Abstract:

The groundwater is one of the main sources for sustainability in the United Arab Emirates (UAE). Intensive developments in Al-Ain area lead to increase water demand, which consequently reduced the overall groundwater quantity in major aquifers. However, in certain residential areas within Al-Ain, it has been noticed that the groundwater level is rising, for example in Sha-ab Al Askher area. The reasons for the groundwater rising phenomenon are yet to be investigated. In this work, twenty four seismic refraction profiles have been carried out along the study pilot area; as well as field measurement of the groundwater level in a number of available water wells in the area. The processed seismic data indicated the deepest and shallowest groundwater levels are 15m and 2.3 meters respectively. This result is greatly consistent with the proper field measurement of the groundwater level. The minimum detected value may be referred to perched subsurface water which may be associated to the infiltration from the surrounding water bodies such as lakes, and elevated farms. The maximum values indicate the accurate groundwater level within the study area. The findings of this work may be considered as a preliminary help to the decision makers.

Keywords: groundwater, shallow seismic method, United Arab Emirates

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Authors: Savita Sindhu, Shruti Vashist

Abstract:

A wireless body area sensor network (WBASN) is composed of a central node and heterogeneous sensors to supervise the physiological signals and functions of the human body. This overwhelmimg area has stimulated new research and calibration processes, especially in the area of WBASN’s attainment and fidelity. In the era of mobility or imbricated WBASN’s, system performance incomparably degrades because of unstable signal integrity. Hence, it is mandatory to define mitigation techniques in the design to avoid interference. There are various mitigation methods available e.g. diversity techniques, equalization, viterbi decoder etc. This paper presents equalization mitigation scheme in WBASNs to improve the signal integrity. Eye diagrams are also given to represent accuracy of the signal. Maximum no. of symbols is taken to authenticate the signal which in turn results in accuracy and increases the overall performance of the system.

Keywords: Wireless body area network, equalizer, RLS, LMS.

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Authors: Vladislav N. Dumachev, Vladimir A. Rodin

Abstract:

By utilizing the system of the recurrence equations, containing two parameters, the dynamics of two antagonistically interconnected populations is studied. The following areas of the system behavior are detected: the area of the stable solutions, the area of cyclic solutions occurrence, the area of the accidental change of trajectories of solutions, and the area of chaos and fractal phenomena. The new two-dimensional diagram of the dynamics of the solutions change (the fractal cabbage) has been obtained. In the cross-section of this diagram for one of the equations the well-known Feigenbaum tree of doubling has been noted.Keywordsbifurcation, chaos, dynamics of populations, fractals

Keywords: bifurcation, chaos, dynamics of populations, fractals

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Authors: Yakup Sahin, Naim Suleyman Ting, Ismail Aksoy

Abstract:

In this paper, an improved active snubber cell is proposed on account of soft switching (SS) family of pulse width modulation (PWM) DC-DC converters. The improved snubber cell provides zero-voltage transition (ZVT) turn on and zero-current transition (ZCT) turn off for main switch. The snubber cell decreases EMI noise and operates with SS in a wide range of line and load voltages. Besides, all of the semiconductor devices in the converter operate with SS. There is no additional voltage and current stress on the main devices. Additionally, extra voltage stress does not occur on the auxiliary switch and its current stress is acceptable value. The improved converter has a low cost and simple structure. The theoretical analysis of converter is clarified and the operating states are given in detail. The experimental results of converter are obtained by prototype of 500 W and 100 kHz. It is observed that the experimental results and theoretical analysis of converter are suitable with each other perfectly.

Keywords: Active snubber cells, DC-DC converters, zero-voltage transition, zero-current transition.

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Authors: R. Mahjoub, K. Maghsoudi Mehraban

Abstract:

In recent years, solid oxide fuel cells have been used as one of the main technologies for the production of electrical energy with high-efficiency ratio, which is used hydrogen and other hydrocarbons as fuels. The fuel cell technology can be used either alone or in hybrid gas turbines systems. In this study, thermodynamics analysis for GT-SOFC hybrid system is developed, and then mass balance and exergy equations have been applied not only on the process but also on the individual components of the hybrid system, which enable us to estimate the thermal efficiency of the hybrid systems. Furthermore, various sources of irreversibility in the solid oxide fuel cell system are discussed, and modeling and parametric analyses like heat and pressure are carried out. This study enables us to consider the irreversible effects of solid oxide fuel cells, and also it leads to the specification of efficiency of the system accurately. Next in the study, both methane and hydrogen as a fuel for SOFC are used and implemented, and finally, our results are compared with other references.

Keywords: hybrid system, gas turbine, entropy and exergy analysis, irreversibility analysis

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Authors: A. D. Parekh, P. R. Tailor

Abstract:

Capacity and efficiency of any refrigerating system diminish rapidly as the difference between the evaporating and condensing temperature is increased by reduction in the evaporator temperature. The single stage vapour compression refrigeration system is limited to an evaporator temperature of -40 0C. Below temperature of -40 0C the either cascade refrigeration system or multi stage vapour compression system is employed. Present work describes thermal design of main three heat exchangers namely condenser (HTS), cascade condenser and evaporator (LTS) of R404A-R508B and R410A-R23 cascade refrigeration system. Heat transfer area of condenser (HTS), cascade condenser and evaporator (LTS) for both systems have been compared and the effect of condensing and evaporating temperature on heat-transfer area for both systems have been studied under same operating condition. The results shows that the required heat-transfer area of condenser and cascade condenser for R410A-R23 cascade system is lower than the R404A-R508B cascade system but heat transfer area of evaporator is similar for both the system. The heat transfer area of condenser and cascade condenser decreases with increase in condensing temperature (Tc), whereas the heat transfer area of cascade condenser and evaporator increases with increase in evaporating temperature (Te).

Keywords: Heat-transfer area, R410A, R404A, R508B, R23, Refrigeration system, Thermal design

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Authors: M. H. Rajikin, S. M. M. Syairah, A. R. Sharaniza

Abstract:

Effects of nicotine on pre-partum body weight and preimplantation embryonic development has been reported previously. Present study was conducted to determine the effects of annatto (Bixa orellana)-derived delta-tocotrienol (TCT) (with presence of 10% gamma-TCT isomer) on the nicotine-induced reduction in body weight and 8-cell embryonic growth in mice. Twenty-four 6-8 weeks old (23-25g) female balb/c mice were randomly divided into four groups (G1-G4; n=6). Those groups were subjected to the following treatments for 7 consecutive days: G1 (control) were gavaged with 0.1 ml tocopherol stripped corn oil. G2 was subcutaneously (s.c.) injected with 3 mg/kg/day of nicotine. G3 received concurrent treatment of nicotine (3 mg/kg/day) and 60 mg/kg/day of δ-TCT mixture (contains 90% delta & 10% gamma isomers) and G4 was given 60 mg/kg/day of δ-TCT mixture alone. Body weights were recorded daily during the treatment. On Day 8, females were superovulated with 5 IU Pregnant Mare’s Serum Gonadotropin (PMSG) for 48 hours followed with 5 IU human Chorionic Gonadotropin (hCG) before mated with males at the ratio of 1:1. Females were sacrificed by cervical dislocation for embryo collection 48 hours post-coitum. Collected embryos were cultured in vitro. Results showed that throughout Day 1 to Day 7, the body weight of nicotine treated group (G2) was significantly lower (p<0.05) than that of G1, G3 and G4. Intervention with δ-TCT mixture (G3) managed to increase the body weight close to the control group. This is also observed in the group treated with δ-TCT mixture alone (G4). The development of 8-cell embryos following in vitro culture (IVC) was totally inhibited in G2. Intervention with δ- TCT mixture (G3) resulted in the production of 8-cell embryos, although it was not up to that of the control group. Treatment with δ- TCT mixture alone (G4) caused significant increase in the average number of produced 8-cell embryo compared to G1. Present data indicated that δ-TCT mixture was able to reverse the body weight loss in nicotine treated mice and the development of 8-cell embryos was also improved. Further analysis on the quality of embryos need to done to confirm the effects of δ-TCT mixture on preimplantation embryos.

Keywords: δ-tocotrienol, body weight, nicotine, preimplantation embryonic development.

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Authors: Forough Ataollahi, Belinda Pingguan-Murphy, Wan Abu Bakar Wan Abas, Noor Azuan Abu Osman

Abstract:

Endothelium proliferation is an important process in cardiovascular homeostasis and can be regulated by extracellular environment, as cells can actively sense mechanical environment. In this study, we evaluated endothelial cell proliferation on PDMS/alumina (Al₂O₃) composites and pure PDMS. The substrates were prepared from pure PDMS and its composites with 5% and 10% Al₂O₃ at curing temperature 50˚C for 4h and then characterized by mechanical, structural and morphological analyses. Higher stiffness was found in the composites compared to the pure PDMS substrate. Cell proliferation of the cultured bovine aortic endothelial cells on substrate materials were evaluated via Resazurin assay and 1, 1’-Dioctadecyl-1, 3, 3, 3’, 3’-Tetramethylindocarbocyanine Perchlorate-Acetylated LDL (Dil-Ac-LDL) cell staining, respectively. The results revealed that stiffer substrates promote more endothelial cells proliferation to the less stiff substrates. Therefore, this study firmly hypothesizes that the stiffness elevates endothelial cells proliferation.

Keywords: Bovine aortic endothelial cells, extra cellular matrix, proliferation, stiffness.

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Authors: A. Maria G. Melero, A. M. Senna, J. A. Domingues, M. A. Hausen, E. Aparecida R. Duek, V. R. Botaro

Abstract:

A hydrogel from cellulose acetate cross linked with ethylenediaminetetraacetic dianhydride (HAC-EDTA) was synthesized by our research group, and submitted to characterization and biological tests. Cytocompatibility analysis was performed by confocal microscopy using human adipocyte derived stem cells (ASCs). The FTIR analysis showed characteristic bands of cellulose acetate and hydroxyl groups and the tensile tests evidence that HAC-EDTA present a Young’s modulus of 643.7 MPa. The confocal analysis revealed that there was cell growth at the surface of HAC-EDTA. After one day of culture the cells presented spherical morphology, which may be caused by stress of the sequestration of Ca²⁺ and Mg²⁺ ions at the cell medium by HAC-EDTA, as demonstrated by ICP-MS. However, after seven days and 14 days of culture, the cells present fibroblastoid morphology, phenotype expected by this cellular type. The results give efforts to indicate this new material as a potential biomaterial for tissue engineering, in the future in vivo approach.

Keywords: Cellulose acetate, hydrogel, biomaterial, cellular growth.

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Authors: C. Y. Chen

Abstract:

As the global climate changes, the threat from landslides and debris flows increases. Learning how a watershed initiates landslides under abnormal rainfall conditions and predicting landslide magnitude and frequency distribution is thus important. Landslides show a power-law distribution in the frequency-area distribution. The distribution curve shows an exponent gradient 1.0 in the Sandpile model test. Will the landslide frequency-area statistics show a distribution similar to the Sandpile model under extreme rainfall conditions? The purpose of the study is to identify the extreme rainfall-induced landslide frequency-area distribution in the Laonong River Basin in southern Taiwan. Results of the analysis show that a lower gradient of landslide frequency-area distribution could be attributed to the transportation and deposition of debris flow areas that are included in the landslide area.

Keywords: Landslide, power-law distribution, GIS.

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Authors: S. C. Santos, S. R. Dionísio, A. L. D. De Andrade, L. R. Roque, A. C. Da Costa, J. L. Ienczak

Abstract:

In this work, two fermentations at different temperatures (25 and 30ºC), with cell recycling, were accomplished to produce ethanol, using a mix of commercial substrates, xylose (70%) and glucose (30%), as organic source for Scheffersomyces stipitis. Five consecutive fermentations of 80 g L-1 (1º, 2º and 3º recycles), 96 g L-1 (4º recycle) and 120 g L-1 (5º recycle)reduced sugars led to a final maximum ethanol concentration of 17.2 and 34.5 g L-1, at 25 and 30ºC, respectively. Glucose was the preferred substrate; moreover xylose startup degradation was initiated after a remaining glucose presence in the medium. Results showed that yeast acid treatment, performed before each cycle, provided improvements on cell viability, accompanied by ethanol productivity of 2.16 g L-1 h- 1 at 30ºC. A maximum 36% of xylose was retained in the fermentation medium and after five-cycle fermentation an ethanol yield of 0.43 g ethanol/g sugars was observed. S. stipitis fermentation capacity and tolerance showed better results at 30ºC with 83.4% of theoretical yield referenced on initial biomass.

Keywords: 5-carbon sugar, cell recycling fermenter, mixed sugars, xylose-fermenting yeast.

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Authors: A. D. Parekh, P. R. Tailor, Tejendra Patel

Abstract:

Capacity and efficiency of any refrigerating system diminish rapidly as the difference between the evaporating and condensing temperature is increased by a reduction in the evaporator temperature. The single stage vapour compression refrigeration system using various refrigerants are limited to an evaporator temperature of -40 0C. Below temperature of -40 0C the either cascade refrigeration system or multi stage vapour compression system is employed. Present work describes thermal design of condenser (HTS), cascade condenser and evaporator (LTS) of R404A-R508B and R410A-R23 cascade refrigeration system. Heat transfer area of condenser, cascade condenser and evaporator for both systems are compared and the effect of condenser and evaporator temperature on heat-transfer area for both systems is studied under same operating condition. The results shows that the required heat-transfer area of condenser and cascade condenser for R410A-R23 cascade system is lower than the R404A-R508B cascade system but heat transfer area of evaporator is similar for both the system. The heat transfer area of condenser and cascade condenser decreases with increase in condenser temperature (Tc), whereas the heat transfer area of cascade condenser and evaporator increases with increase in evaporator temperature (Te).

Keywords: Heat-transfer area, R410A, R404A, R508B, R23, Refrigeration system, Thermal design

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Authors: M. Azizur Rahman, Tamotsu Oomori

Abstract:

Calcite aCalcite and aragonite are the two common polymorphs of CaCO3 observed as biominerals. It is universal that the sea water contents a high Mg2+ (50mM) relative to Ca2+ (10mM). In vivo crystallization, Mg2+ inhibits calcite formation. For this reason, stony corals skeleton may be formed only aragonite crystals in the biocalcification. It is special in case of soft corals of which formed only calcite crystal; however, this interesting phenomenon, still uncharacterized in the marine environment, has been explored in this study using newly purified cell-free proteins isolated from the endoskeletal sclerites of soft coral. By recording the decline of pH in vitro, the control of CaCO3 nucleation and crystal growth by the cellfree proteins was revealed. Using Atomic Force Microscope, here we find that these endoskeletal cell-free proteins significantly design the morphological shape in the molecular-scale kinetics of crystal formation and those proteins act as surfactants to promote ion attachment at calcite steps.nd aragonite are the two common polymorphs of CaCO3 observed as biominerals. It is universal that the sea water contents a high Mg2+ (50mM) relative to Ca2+ (10mM). In vivo crystallization, Mg2+ inhibits calcite formation. For this reason, stony corals skeleton may be formed only aragonite crystals in the biocalcification. It is special in case of soft corals of which formed only calcite crystal; however, this interesting phenomenon, still uncharacterized in the marine environment, has been explored in this study using newly purified cell-free proteins isolated from the endoskeletal sclerites of soft coral. By recording the decline of pH in vitro, the control of CaCO3 nucleation and crystal growth by the cell-free proteins was revealed. Using Atomic Force Microscope, here we find that these endoskeletal cell-free proteins significantly design the morphological shape in the molecular-scale kinetics of crystal formation and those proteins act as surfactants to promote ion attachment at calcite steps. KeywordsBiomineralization, Calcite, Cell-free protein, Soft coral

Keywords: Biomineralization, Calcite, Cell-free protein, Soft coral

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Authors: M. Sadeghi, H. Pezeshk, R. Tusserkani, A. Sharifi Zarchi, A. Malekpour, M. Foroughmand, S. Goliaei, M. Totonchi, N. Ansari–Pour

Abstract:

The role and relative importance of intrinsic and extrinsic factors in the development of complex diseases such as cancer still remains a controversial issue. Determining the amount of variation explained by these factors needs experimental data and statistical models. These models are nevertheless based on the occurrence and accumulation of random mutational events during stem cell division, thus rendering cancer development a stochastic outcome. We demonstrate that not only individual genome sequencing is uninformative in determining cancer risk, but also assigning a unique genome sequence to any given individual (healthy or affected) is not meaningful. Current whole-genome sequencing approaches are therefore unlikely to realize the promise of personalized medicine. In conclusion, since genome sequence differs from cell to cell and changes over time, it seems that determining the risk factor of complex diseases based on genome sequence is somewhat unrealistic, and therefore, the resulting data are likely to be inherently uninformative.

Keywords: Cancer risk, extrinsic factors, genome sequencing, intrinsic factors.

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Authors: Sun Jiaojiao, Fu Jiayan

Abstract:

At present, in China, the research about the urban sustainability construction is still in the exploratory stage. The ecological problems of the coastal area are more sensitive and complicated. In the background of global warming with serious ecological damage, this paper deeply researches on the main characteristics of urban sustainability and measures how to build urban sustainability. Through combining regional environmental with economic ability along the coastal area, then authors put forward the system planning framework, construction strategy and the evaluation index system, in order to seek the way of building urban sustainability along coastal area in China.

Keywords: Urban sustainability, coastal areas, construction strategy, evaluation index system.

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Authors: Yue Du, Sahan C. B. Herath, Qing-Guo Wang, Harry Asada, Peter C. Y. Chen

Abstract:

Mechanical interaction between endothelial cells (ECs) and the extracellular matrix (or collagen gel) is known to influence the sprouting response of endothelial cells during angiogenesis. This influence is believed to impact on the capability of endothelial cells to sense soluble chemical cues. Quantitative analysis of endothelial-cell-mediated displacement of the collagen gel provides a means to explore this mechanical interaction. Existing analysis in this context is generally limited to 2D settings. In this paper, we investigate the mechanical interaction between endothelial cells and the extracellular matrix in terms of the endothelial-cellmediated displacement of the collagen gel in both 2D and 3D. Digital image correlation and Digital volume correlation are applied on confocal reflectance image stacks to analyze cell-mediated displacement of the gel. The skeleton of the sprout is extracted from phase contrast images and superimposed on the displacement field to further investigate the link between the development of the sprout and the displacement of the gel.

Keywords: Angiogenesis, digital image correlation, digital volume correlation, interaction between ECs and ECM.

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Authors: Paola Lecca

Abstract:

Modeling and simulation of biochemical reactions is of great interest in the context of system biology. The central dogma of this re-emerging area states that it is system dynamics and organizing principles of complex biological phenomena that give rise to functioning and function of cells. Cell functions, such as growth, division, differentiation and apoptosis are temporal processes, that can be understood if they are treated as dynamic systems. System biology focuses on an understanding of functional activity from a system-wide perspective and, consequently, it is defined by two hey questions: (i) how do the components within a cell interact, so as to bring about its structure and functioning? (ii) How do cells interact, so as to develop and maintain higher levels of organization and functions? In recent years, wet-lab biologists embraced mathematical modeling and simulation as two essential means toward answering the above questions. The credo of dynamics system theory is that the behavior of a biological system is given by the temporal evolution of its state. Our understanding of the time behavior of a biological system can be measured by the extent to which a simulation mimics the real behavior of that system. Deviations of a simulation indicate either limitations or errors in our knowledge. The aim of this paper is to summarize and review the main conceptual frameworks in which models of biochemical networks can be developed. In particular, we review the stochastic molecular modelling approaches, by reporting the principal conceptualizations suggested by A. A. Markov, P. Langevin, A. Fokker, M. Planck, D. T. Gillespie, N. G. van Kampfen, and recently by D. Wilkinson, O. Wolkenhauer, P. S. Jöberg and by the author.

Keywords: Mathematical structure, algorithmic implementation, biochemical network models.

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Authors: Abu Bakar Sambah, Fusanori Miura

Abstract:

Remote sensing image processing, spatial data analysis through GIS approach, and analytical hierarchy process were introduced in this study for assessing the vulnerability area and inundation area due to tsunami hazard in the area of Rikuzentakata, Iwate Prefecture, Japan. Appropriate input parameters were derived from GSI DEM data, ALOS AVNIR-2, and field data. We used the parameters of elevation, slope, shoreline distance, and vegetation density. Five classes of vulnerability were defined and weighted via pairwise comparison matrix. The assessment results described that 14.35km² of the study area was under tsunami vulnerability zone. Inundation areas are those of high and slightly high vulnerability. The farthest area reached by a tsunami was about 7.50km from the shoreline and shows that rivers act as flooding strips that transport tsunami waves into the hinterland. This study can be used for determining a priority for land-use planning in the scope of tsunami hazard risk management.

Keywords: AHP, GIS, remote sensing, tsunami vulnerability.

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Authors: Helyane Bronoski Borges, Júlio Cesar Nievola

Abstract:

The most important subtype of non-Hodgkin-s lymphoma is the Diffuse Large B-Cell Lymphoma. Approximately 40% of the patients suffering from it respond well to therapy, whereas the remainder needs a more aggressive treatment, in order to better their chances of survival. Data Mining techniques have helped to identify the class of the lymphoma in an efficient manner. Despite that, thousands of genes should be processed to obtain the results. This paper presents a comparison of the use of various attribute selection methods aiming to reduce the number of genes to be searched, looking for a more effective procedure as a whole.

Keywords: Attribute selection, data mining.

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Authors: Shinya Yokoyama, Katsunari Jonouchi, Kenji Imou

Abstract:

This paper discusses the utilization of marine biomass as an energy resource in Japan. A marine biomass energy system in Japan was proposed consisting of seaweed cultivation (Laminaria japonica) at offshore marine farms, biogas production via methane fermentation of the seaweeds, and fuel cell power generation driven by the generated biogas. We estimated energy output, energy supply potential, and CO2 mitigation in Japan on the basis of the proposed system. As a result, annual energy production was estimated to be 1.02-109 kWh/yr at nine available sites. Total CO2 mitigation was estimated to be 1.04-106 tonnes per annum at the nine sites. However, the CO2 emission for the construction of relevant facilities is not taken into account in this paper. The estimated CO2 mitigation is equivalent to about 0.9% of the required CO2 mitigation for Japan per annum under the Kyoto Protocol framework.

Keywords: CO2 mitigation, Fuel cell power generation, Laminaria japonica, Marine biomass, Seaweed.

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Authors: Surya Prakash, Sunil Kumar Sinha

Abstract:

This paper deals with the application of artificial neural network (ANN) and fuzzy based Adaptive Neuro Fuzzy Inference System(ANFIS) approach to Load Frequency Control (LFC) of multi unequal area hydro-thermal interconnected power system. The proposed ANFIS controller combines the advantages of fuzzy controller as well as quick response and adaptability nature of ANN. Area-1 and area-2 consists of thermal reheat power plant whereas area-3 and area-4 consists of hydro power plant with electric governor. Performance evaluation is carried out by using intelligent controller like ANFIS, ANN and Fuzzy controllers and conventional PI and PID control approaches. To enhance the performance of intelligent and conventional controller sliding surface is included. The performances of the controllers are simulated using MATLAB/SIMULINK package. A comparison of ANFIS, ANN, Fuzzy, PI and PID based approaches shows the superiority of proposed ANFIS over ANN & fuzzy, PI and PID controller for 1% step load variation.

Keywords: Load Frequency Control (LFC), ANFIS, ANN & Fuzzy, PI, PID Controllers, Area Control Error (ACE), Tie-line, MATLAB / SIMULINK.

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Authors: Athanasios T. Alexiou, Maria M. Psiha, John A. Rekkas, Panayiotis M. Vlamos

Abstract:

Mitochondria are dynamic organelles, capable to interact with each other. While the number of mitochondria in a cell varies, their quality and functionality depends on the operation of fusion, fission, motility and mitophagy. Nowadays, several researches declare as an important factor in neurogenerative diseases the disruptions in the regulation of mitochondrial dynamics. In this paper a stochastic model in BioAmbients calculus is presented, concerning mitochondrial fusion and its distribution in the renewal of mitochondrial population in a cell. This model describes the successive and dependent stages of protein synthesis, protein-s activation and merging of two independent mitochondria.

Keywords: Mitochondrial Dynamics, P-Calculus, StochasticModeling.

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Authors: P. Mekpruksawong, S. Chuenchooklin, T. Ichikawa

Abstract:

The aim of research project is to evaluate quantity and quality for conjunctive use of groundwater and surface water in lower in the Lower Nam Kam area, Thailand, even though there have been hints of saline soil and water. The mathematical model named WUSMO and MIKE Basin were applied for the calculation of crop water utilization. Results of the study showed that, in irrigation command area, water consumption rely on various sources; rain water 21.56%, irrigation water 78.29%, groundwater and some small surface storage 0.15%. Meanwhile, for non-irrigation command area, water consumption depends on the Nam Kam and Nambang stream 42%, rain water 36.75% and groundwater and some small surface storage 19.18%. Samples of surface water and groundwater were collected for 2 seasons. The criterion was determined for the assessment of suitable water for irrigation. It was found that this area has very limited sources of suitable water for irrigation.

Keywords: Conjunctive use, Groundwater, Surface water, Saline soil.

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Authors: Mohammad Ali Hosseinpour, Hossein Ghoreishi, Saeid Gitipour, Mona Jafarnejad

Abstract:

REY area has been located in Tehran Province and several archaeological ruins of this area indicate that the settlement in this area has been started since several thousand years ago. In this paper, the main investigation items consist of analysis of oil components and groundwater quality inside the wells. By finding the contents of oil in the well, it is possible to find out the pollution source by comparing the oil contents of well with other oil products that are used inside and outside of the oil farm. Investigation items consist of analysis of BTEX (Benzene, Toluene, Ethyl-benzene, Xylene), Gas chromatographic distillation characteristics, Water content, Density, Sulfur content, Lead content, Atmospheric distillation, MTBE(Methyl tertiary butyl ether). Analysis of polluting oil components showed that except MW(Monitoring Well)10 and MW 15 that oil with slightly heavy components was detected in them; with a high possibility the polluting oil is light oil.

Keywords: BTEX, Oil Component, REY Area, Tehran Oil Refining Company (T.O.R.C) .

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