Search results for: biological effects of electric field on human body
7253 Comparative in silico and in vitro Study of N-(1- Methyl-2-Oxo-2-N-Methyl Anilino-Ethyl) Benzene Sulfonamide and Its Analogues as an Anticancer Agent
Authors: Pamita Awasthi, Kirna, Shilpa Dogra, Manu Vatsal, Ritu Barthwal
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Doxorubicin, also known as Adriamycin, is an anthracycline class of drug used in cancer chemotherapy. It is used in the treatment of non-Hodgkin’s lymphoma, multiple myeloma, acute leukemia, breast cancer, lung cancer, endometrium cancer and ovary cancers. It functions via intercalating DNA and ultimately killing cancer cells. The major side effects of doxorubicin are hair loss, myelosuppression, nausea & vomiting, oesophagitis, diarrhea, heart damage and liver dysfunction. The minor modifications in the structure of compound exhibit large variation in the biological activity, has prompted us to carry out the synthesis of sulfonamide derivatives. Sulfonamide is an important feature with broad spectrum of biological activity such as antiviral, antifungal, diuretics, antiinflammatory, antibacterial and anticancer activities. Structure of the synthesized compound N-(1-methyl-2-oxo-2-N-methyl anilinoethyl) benzene sulfonamide confirmed by proton nuclear magnetic resonance (1H NMR),13C NMR, Mass and FTIR spectroscopic tools to assure the position of all protons and hence stereochemistry of the molecule. Further we have reported the binding potential of synthesized sulfonamide analogues in comparison to doxorubicin drug using Auto Dock 4.2 software. Computational binding energy (B.E.) and inhibitory constant (Ki) has been evaluated for the synthesized compound in comparison of doxorubicin against Poly (dA-dT).Poly (dA-dT) and Poly (dG-dC).Poly (dG-dC) sequences. The in vitro cytotoxic study against human breast cancer cell lines confirms the better anticancer activity of the synthesized compound over currently in use anticancer drug doxorubicin. The IC50 value of the synthesized compound is 7.12 μM whereas for doxorubicin is 7.2 μM.
Keywords: Anticancer, Auto Dock, Doxorubicin, Sulfonamide.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 23417252 The Effect of Combining Real Experimentation With Virtual Experimentation on Students-Success
Authors: I. Oral, E. Bozkurt, H. Guzel
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The purpose of this study was to investigate the effect of combining Real Experimentation (RE) With Virtual Experimentation (VE) on students- conceptual understanding of photo electric effect. To achieve this, a pre–post comparison study design was used that involved 46 undergraduate students. Two groups were set up for this study. Participants in the control group used RE to learn photo electric effect, whereas, participants in the experimental group used RE in the first part of the curriculum and VE in another part. Achievement test was given to the groups before and after the application as pre-test and post test. The independent samples t- test, one way Anova and Tukey HSD test were used for testing the data obtained from the study. According to the results of analyzes, the experimental group was found more successful than the control group.Keywords: Computer Based Teaching, Java, Physics Education, Virtual Laboratory.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18087251 Experimental Investigation with Different Inclination Angles on Copper Oscillating Heat Pipes Performance Using Fe2O3/Kerosene under Magnetic Field
Authors: H. R. Goshayeshi, M. Mansori, M. Ahmady, M. Khaloyi
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This paper presents the result of an experimental investigation regarding the use of Fe2O3 nanoparticles added to kerosene as a working fluid, under magnetic field for Copper Oscillating Heat pipe with inclination angle of 0°(horizontal), 15°, 30°,45°, 60°,75° and 90° (vertical). The following were examined; measure the temperature distribution and heat transfer rate on Oscillating Heat Pipe (OHP), with magnetic field under different angles. Results showed that the addition of Fe2O3 nanoparticles under magnetic field improved thermal performance of OHP especially in 75°.Keywords: Copper oscillating heat pipe, Fe2O3, magnetic field, inclination angles.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21717250 Improving Human Hand Localization in Indoor Environment by Using Frequency Domain Analysis
Authors: Wipassorn Vinicchayakul, Pichaya Supanakoon, Sathaporn Promwong
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A human’s hand localization is revised by using radar cross section (RCS) measurements with a minimum root mean square (RMS) error matching algorithm on a touchless keypad mock-up model. RCS and frequency transfer function measurements are carried out in an indoor environment on the frequency ranged from 3.0 to 11.0 GHz to cover federal communications commission (FCC) standards. The touchless keypad model is tested in two different distances between the hand and the keypad. The initial distance of 19.50 cm is identical to the heights of transmitting (Tx) and receiving (Rx) antennas, while the second distance is 29.50 cm from the keypad. Moreover, the effects of Rx angles relative to the hand of human factor are considered. The RCS input parameters are compared with power loss parameters at each frequency. From the results, the performance of the RCS input parameters with the second distance, 29.50 cm at 3 GHz is better than the others.
Keywords: Radar cross section (RCS), fingerprint-based localization, minimum root mean square (RMS) error matching algorithm, touchless keypad model.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13567249 Experimental Simulation Set-Up for Validating Out-Of-The-Loop Mitigation when Monitoring High Levels of Automation in Air Traffic Control
Authors: Oliver Ohneiser, Francesca De Crescenzio, Gianluca Di Flumeri, Jan Kraemer, Bruno Berberian, Sara Bagassi, Nicolina Sciaraffa, Pietro Aricò, Gianluca Borghini, Fabio Babiloni
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An increasing degree of automation in air traffic will also change the role of the air traffic controller (ATCO). ATCOs will fulfill significantly more monitoring tasks compared to today. However, this rather passive role may lead to Out-Of-The-Loop (OOTL) effects comprising vigilance decrement and less situation awareness. The project MINIMA (Mitigating Negative Impacts of Monitoring high levels of Automation) has conceived a system to control and mitigate such OOTL phenomena. In order to demonstrate the MINIMA concept, an experimental simulation set-up has been designed. This set-up consists of two parts: 1) a Task Environment (TE) comprising a Terminal Maneuvering Area (TMA) simulator as well as 2) a Vigilance and Attention Controller (VAC) based on neurophysiological data recording such as electroencephalography (EEG) and eye-tracking devices. The current vigilance level and the attention focus of the controller are measured during the ATCO’s active work in front of the human machine interface (HMI). The derived vigilance level and attention trigger adaptive automation functionalities in the TE to avoid OOTL effects. This paper describes the full-scale experimental set-up and the component development work towards it. Hence, it encompasses a pre-test whose results influenced the development of the VAC as well as the functionalities of the final TE and the two VAC’s sub-components.
Keywords: Automation, human factors, air traffic controller, MINIMA, OOTL, Out-Of-The-Loop, EEG, electroencephalography, HMI, human machine interface.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14527248 Pareidolia and Perception of Anger in Vehicle Styles: Survey Results
Authors: Alan S. Hoback
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Most people see human faces in car front and back ends because of the process of pareidolia. 96 people were surveyed to see how many of them saw a face in the vehicle styling. Participants were aged 18 to 72 years. 94% of the participants saw faces in the front-end design of production models. All participants that recognized faces indicated that most styles showed some degree of an angry expression. It was found that women were more likely to see faces in inanimate objects. However, with respect to whether women were more likely to perceive anger in the vehicle design, the results need further clarification. Survey responses were correlated to the design features of vehicles to determine what cues the respondents were likely looking at when responding. Whether the features looked anthropomorphic was key to anger perception. Features such as the headlights which could represent eyes and the air intake that could represent a mouth had high correlations to trends in scores. Results are compared among models, makers, by groupings of body styles classifications for the top 12 brands sold in the US, and by year for the top 20 models sold in the US in 2016. All of the top models sold increased in perception of an angry expression over the last 20 years or since the model was introduced, but the relative change varied by body style grouping.
Keywords: Aggressive driving, face recognition, road rage, vehicle styling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 8017247 Metabolomics Profile Recognition for Cancer Diagnostics
Authors: Valentina L. Kouznetsova, Jonathan W. Wang, Igor F. Tsigelny
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Metabolomics has become a rising field of research for various diseases, particularly cancer. Increases or decreases in metabolite concentrations in the human body are indicative of various cancers. Further elucidation of metabolic pathways and their significance in cancer research may greatly spur medicinal discovery. We analyzed the metabolomics profiles of lung cancer. Thirty-three metabolites were selected as significant. These metabolites are involved in 37 metabolic pathways delivered by MetaboAnalyst software. The top pathways are glyoxylate and dicarboxylate pathway (its hubs are formic acid and glyoxylic acid) along with Citrate cycle pathway followed by Taurine and hypotaurine pathway (the hubs in the latter are taurine and sulfoacetaldehyde) and Glycine, serine, and threonine pathway (the hubs are glycine and L-serine). We studied interactions of the metabolites with the proteins involved in cancer-related signaling networks, and developed an approach to metabolomics biomarker use in cancer diagnostics. Our analysis showed that a significant part of lung-cancer-related metabolites interacts with main cancer-related signaling pathways present in this network: PI3K–mTOR–AKT pathway, RAS–RAF–ERK1/2 pathway, and NFKB pathway. These results can be employed for use of metabolomics profiles in elucidation of the related cancer proteins signaling networks.Keywords: Cancer, metabolites, metabolic pathway, signaling pathway.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 13917246 Effect of Twelve Weeks Brisk Walking on Blood Pressure, Body Mass Index, and Anthropometric Circumference of Obese Males
Authors: Kaukab Azeem
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Introduction: Obesity is a major health risk issue in the present day of life for one and all globally. Obesity is one of the major concerns for public health according to recent increasing trends in obesity-related diseases such as Type 2 diabetes. ( Kazuya, 1994).and hyperlipidemia, (Sakata,1990) .which are more prevalent in Japanese adults with body mass index (BMI) values Z25 kg/m2.( Japanese Ministry of Health and Welfare,1997). The purpose of the study was to assess the effect of twelve weeks of brisk walking on blood pressure and body mass index, anthropometric measurements of obese males. Method: Thirty obese (BMI= above 30) males, aged 18 to 22 years, were selected from King Fahd University of Petroleum & Minerals, Saudi Arabia. The subject-s height (cm) was measured using a stadiometer and body mass (kg) was measured with a electronic weighing machine. BMI was subsequently calculated (kg/m2). The blood pressure was measured with standardized sphygmomanometer in mm of Hg. All the measurements were taken twice before and twice after the experimental period. The pre and post anthropometric measurements of waist and hip circumference were measured with the steel tape in cm. The subjects underwent walking schedule two times in a week for 12 weeks. The 45 minute sessions of brisk walking were undertaken at an average intensity of 65% to 85% of maximum HR (HRmax; calculated as 220-age). Results & Discussion: Statistical findings revealed significant changes from pre test to post test in case of both systolic blood pressure and diastolic blood pressure in the walking group. Results also showed significant decrease in their body mass index and anthropometric measurements i.e. (waist & hip circumference). Conclusion: It was concluded that twelve weeks brisk walking is beneficial for lowering of blood pressure, body mass index, and anthropometric circumference of obese males.Keywords: Anthropometric, Blood pressure, Body mass index
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 30747245 Sun, Salon, and Cosmetic Tanning: Predictors and Motives
Authors: Andrew Reilly, Nancy A. Rudd
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The appearance management behavior of tanning by gay men is examined through the lens of Impression Formation. The study proposes that body image, self-esteem, and internalized homophobia are connected and affect the motives for engaging in sun, salon, and cosmetic tanning. Motives examined were: to look masculine, to look attractive to (potential) partners, to look attractive in general, to socialize, to meet a peer standard, and for personal satisfaction. Using regression analysis to examine data of 103 gay men who engage in at least one method of tanning, results reveal that components of body image and internalized homophobia–but not self-esteem–are linked to various motives and methods of tanning. These findings support and extend the literature of Impression Formation Theory and provide practitioners in the health and healthrelated fields new avenues to pursue when dealing with diseases related to tanning.
Keywords: Body image, gay men, tanning.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15497244 Taxonomy of Threats and Vulnerabilities in Smart Grid Networks
Authors: Faisal Al Yahmadi, Muhammad R. Ahmed
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Electric power is a fundamental necessity in the 21st century. Consequently, any break in electric power is probably going to affect the general activity. To make the power supply smooth and efficient, a smart grid network is introduced which uses communication technology. In any communication network, security is essential. It has been observed from several recent incidents that adversary causes an interruption to the operation of networks. In order to resolve the issues, it is vital to understand the threats and vulnerabilities associated with the smart grid networks. In this paper, we have investigated the threats and vulnerabilities in Smart Grid Networks (SGN) and the few solutions in the literature. Proposed solutions showed developments in electricity theft countermeasures, Denial of services attacks (DoS) and malicious injection attacks detection model, as well as malicious nodes detection using watchdog like techniques and other solutions.
Keywords: Smart grid network, security, threats, vulnerabilities.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5957243 Evaluation of the Weight-Based and Fat-Based Indices in Relation to Basal Metabolic Rate-to-Weight Ratio
Authors: Orkide Donma, Mustafa M. Donma
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Basal metabolic rate is questioned as a risk factor for weight gain. The relations between basal metabolic rate and body composition have not been cleared yet. The impact of fat mass on basal metabolic rate is also uncertain. Within this context, indices based upon total body mass as well as total body fat mass are available. In this study, the aim is to investigate the potential clinical utility of these indices in the adult population. 287 individuals, aged from 18 to 79 years, were included into the scope of the study. Based upon body mass index values, 10 underweight, 88 normal, 88 overweight, 81 obese, and 20 morbid obese individuals participated. Anthropometric measurements including height (m), and weight (kg) were performed. Body mass index, diagnostic obesity notation model assessment index I, diagnostic obesity notation model assessment index II, basal metabolic rate-to-weight ratio were calculated. Total body fat mass (kg), fat percent (%), basal metabolic rate, metabolic age, visceral adiposity, fat mass of upper as well as lower extremities and trunk, obesity degree were measured by TANITA body composition monitor using bioelectrical impedance analysis technology. Statistical evaluations were performed by statistical package (SPSS) for Windows Version 16.0. Scatterplots of individual measurements for the parameters concerning correlations were drawn. Linear regression lines were displayed. The statistical significance degree was accepted as p < 0.05. The strong correlations between body mass index and diagnostic obesity notation model assessment index I as well as diagnostic obesity notation model assessment index II were obtained (p < 0.001). A much stronger correlation was detected between basal metabolic rate and diagnostic obesity notation model assessment index I in comparison with that calculated for basal metabolic rate and body mass index (p < 0.001). Upon consideration of the associations between basal metabolic rate-to-weight ratio and these three indices, the best association was observed between basal metabolic rate-to-weight and diagnostic obesity notation model assessment index II. In a similar manner, this index was highly correlated with fat percent (p < 0.001). Being independent of the indices, a strong correlation was found between fat percent and basal metabolic rate-to-weight ratio (p < 0.001). Visceral adiposity was much strongly correlated with metabolic age when compared to that with chronological age (p < 0.001). In conclusion, all three indices were associated with metabolic age, but not with chronological age. Diagnostic obesity notation model assessment index II values were highly correlated with body mass index values throughout all ranges starting with underweight going towards morbid obesity. This index is the best in terms of its association with basal metabolic rate-to-weight ratio, which can be interpreted as basal metabolic rate unit.
Keywords: Basal metabolic rate, body mass index, children, diagnostic obesity notation model assessment index, obesity.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 10557242 The Role of Social and Technical Lean Implementation in Improving Operational Performance: Insights from the Pharmaceutical Industry
Authors: M. Bernasconi, M. Grothkopp, T. Friedli
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The objective of this paper is to examine the relationships between technical and social lean bundles as well as operational performance in the context of the pharmaceutical industry. We investigate the direct and mediating effects of the lean bundles Total Productive Maintenance (TPM), Total Quality Management (TQM), Just-In-Time (JIT), and Human Resource Management (HRM) on operational performance. Our analysis relies on 113 manufacturing facilities from the St.Gallen OPEX benchmarking database. The results show that HRM has a positive indirect effect on operational performance mediated by the technical lean bundles.
Keywords: Human resource management, operational performance, pharmaceutical industry, technical lean practices.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5887241 FEM Simulation of Triple Diffusive Magnetohydrodynamics Effect of Nanofluid Flow over a Nonlinear Stretching Sheet
Authors: Rangoli Goyal, Rama Bhargava
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The triple diffusive boundary layer flow of nanofluid under the action of constant magnetic field over a non-linear stretching sheet has been investigated numerically. The model includes the effect of Brownian motion, thermophoresis, and cross-diffusion; slip mechanisms which are primarily responsible for the enhancement of the convective features of nanofluid. The governing partial differential equations are transformed into a system of ordinary differential equations (by using group theory transformations) and solved numerically by using variational finite element method. The effects of various controlling parameters, such as the magnetic influence number, thermophoresis parameter, Brownian motion parameter, modified Dufour parameter, and Dufour solutal Lewis number, on the fluid flow as well as on heat and mass transfer coefficients (both of solute and nanofluid) are presented graphically and discussed quantitatively. The present study has industrial applications in aerodynamic extrusion of plastic sheets, coating and suspensions, melt spinning, hot rolling, wire drawing, glass-fibre production, and manufacture of polymer and rubber sheets, where the quality of the desired product depends on the stretching rate as well as external field including magnetic effects.Keywords: FEM, Thermophoresis, Diffusiophoresis, Brownian motion.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14517240 Broadening of Raw Materials in the Steel Industry, by Recycling and Recovery Wastes
Authors: A. Todorut, T. Heput
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In technological processes, in addition to the main product, result a large amount of materials, called wastes, but due to the possibilities of recovery, by means of recycling and reusing it can fit in the category of by-products. These large amounts of dust from the steel industry are a major problem in terms of environmental and human health, landscape, etc. Solving these problems, the impressive amounts of waste can be done through their proper management and recovery for every type of waste. In this article it was watched the capitalizing through pelleting and briquetting of small and powdery waste aiming to obtain the sponge iron as raw material, used in blast furnaces and electric arc furnaces. The data have been processed in the Excel spreadsheet program, being presented in the form of diagrams.Keywords: Agglomeration, industry, iron, pellets, wastes.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15467239 An Investigation on the Effect of Various Noises on Human Sensibility by using EEG Signal
Authors: Wonhak Cho, Jongkwan Lee, Taeyoon Son, Hyeonki Choi
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Noise causes significant sensibility changes on a human. This study investigated the effect of five different noises on electroencephalogram (EEG) and subjective evaluation. Six human subjects were exposed to classic piano, ocean wave, alarm in army, ambulance, mosquito noise and EEG data were collected during the experimental session. Alpha band activity in the mosquito noise was smaller than that in the classic piano. Alpha band activity decreased 43.4 ± 8.2 % in the mosquito noise. On the other hand, Beta band activity in the mosquito noise was greater than that in the classic piano. Beta band activity increased 60.1 ± 10.7 % in the mosquito noise. The advances from this study may aid the product design process with human sensibility engineering. This result may provide useful information in designing a human-oriented product to avoid the stress.
Keywords: Electroencephalogram, Human sensibility, Human-oriented product design, Noise.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 15287238 Effects of Global Warming on Climate Change in Udon Thani Province in the Period in 60 Surrounding Years (A.D.1951-2010)
Authors: T. Santiboon
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This research were investigated, determined, and analyzed of the climate characteristically change in the provincial Udon Thani in the period of 60 surrounding years from 1951 to 2010 A.D. that it-s transferred to effects of climatologically data for determining global warming. Statistically significant were not found for the 60 years- data (R2<0.81). Statistically significant were found after adapted data followed as the Sun Spot cycle in 11 year periods, at the level 0.001 (R2= 1.00). These results indicate the Udon Thani-s weather are affected change; temperatures and evaporation were increased, but rainfall and number days of rainfall, cyclone storm, wind speed, and humidity, forest assessment were decreased. The effects of thermal energy from the sun radiation energy and human activities that they-re followed as the sunspot cycle are able to be predicted from the last to the future of the uniformitarian-s the climate change and global warming effect of the world.Keywords: Climate Change, Global Warming, Udon Thani Province Weather
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21097237 Is Cognitive Dissonance an Intrinsic Property of the Human Mind? An Experimental Solution to a Half-Century Debate
Authors: Álvaro Machado Dias, Eduardo Oda, Henrique Teruo Akiba, Leo Arruda, Luiz Felipe Bruder
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Cognitive Dissonance can be conceived both as a concept related to the tendency to avoid internal contradictions in certain situations, and as a higher order theory about information processing in the human mind. In the last decades, this last sense has been strongly surpassed by the former, as nearly all experiment on the matter discuss cognitive dissonance as an output of motivational contradictions. In that sense, the question remains: is cognitive dissonance a process intrinsically associated with the way that the mind processes information, or is it caused by such specific contradictions? Objective: To evaluate the effects of cognitive dissonance in the absence of rewards or any mechanisms to manipulate motivation. Method: To solve this question, we introduce a new task, the hypothetical social arrays paradigm, which was applied to 50 undergraduate students. Results: Our findings support the perspective that the human mind shows a tendency to avoid internal dissonance even when there are no rewards or punishment involved. Moreover, our findings also suggest that this principle works outside the conscious level.
Keywords: Cognitive Dissonance, Cognitive Psychology, Information Processing.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16397236 Lattice Boltzmann Simulation of MHD Natural Convection in a Nanofluid-Filled Enclosure with Non-Uniform Heating on Both Side Walls
Authors: Imen Mejri, Ahmed Mahmoudi, Mohamed A. Abbassi, Ahmed Omri
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This paper examines the natural convection in a square enclosure filled with a water-Al2O3 nanofluid and is subjected to a magnetic field. The side walls of the cavity have spatially varying sinusoidal temperature distributions. The horizontal walls are adiabatic. Lattice Boltzmann method (LBM) is applied to solve the coupled equations of flow and temperature fields. This study has been carried out for the pertinent parameters in the following ranges: Rayleigh number of the base fluid, Ra=103 to 106, Hartmann number varied from Ha=0 to 90, phase deviation (γ=0, π/4, π/2, 3π/4 and π) and the solid volume fraction of the nanoparticles between Ø = 0 and 6%. The results show that the heat transfer rate increases with an increase of the Rayleigh number but it decreases with an increase of the Hartmann number. For γ=π/2 and Ra=105 the magnetic field augments the effect of nanoparticles. At Ha=0, the greatest effects of nanoparticles are obtained at γ = 0 and π/4 for Ra=104 and 105 respectively.
Keywords: Lattice Boltzmann Method, magnetic field, Natural convection, nanofluid, Sinusoidal temperature distribution.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 30147235 Computational Study on Cardiac-Coronary Interaction in Terms of Coronary Flow-Pressure Waveforms in Presence of Drugs: Comparison Between Simulated and In Vivo Data
Authors: C. De Lazzari, E. Del Prete, I. Genuini, F. Fedele
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Cardiovascular human simulator can be a useful tool in understanding complex physiopathological process in cardiocirculatory system. It can also be a useful tool in order to investigate the effects of different drugs on hemodynamic parameters. The aim of this work is to test the potentiality of our cardiovascular numerical simulator CARDIOSIM© in reproducing flow/pressure coronary waveforms in presence of two different drugs: Amlodipine (AMLO) and Adenosine (ADO). In particular a time-varying intramyocardial compression, assumed to be proportional to the left ventricular pressure, was related to the venous coronary compliances in order to study its effects on the coronary blood flow and the flow/pressure loop. Considering that coronary circulation dynamics is strongly interrelated with the mechanics of the left ventricular contraction, relaxation, and filling, the numerical model allowed to analyze the effects induced by the left ventricular pressure on the coronary flow.Keywords: Cardiovascular system, Coronary blood flow, Hemodynamic, Numerical simulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17357234 Hand Motion and Gesture Control of Laboratory Test Equipment Using the Leap Motion Controller
Authors: Ian A. Grout
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In this paper, the design and development of a system to provide hand motion and gesture control of laboratory test equipment is considered and discussed. The Leap Motion controller is used to provide an input to control a laboratory power supply as part of an electronic circuit experiment. By suitable hand motions and gestures, control of the power supply is provided remotely and without the need to physically touch the equipment used. As such, it provides an alternative manner in which to control electronic equipment via a PC and is considered here within the field of human computer interaction (HCI).
Keywords: Control, hand gesture, human computer interaction, test equipment.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 9767233 Development of Transmission Line Sleeve Inspection Robot
Authors: Jae-Kyung Lee, Nam-Joon Jung, Byung-Hak Cho
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The line sleeves on power transmission line connects two conductors while the transmission line is constructing. However, the line sleeves sometimes cause transmission line break down, because the line sleeves are deteriorated and decayed by acid rain. When the transmission line is broken, the economical loss is huge. Therefore the line sleeves on power transmission lines should be inspected periodically to prevent power failure. In this paper, Korea Electric Power Research Institute reviewed several robots to inspect line status and proposes a robot to inspect line sleeve by measuring magnetic field on line sleeve. The developed inspection tool can reliable to move along transmission line and overcome several obstacles on transmission line. The developed system is also applied on power transmission line and verified the efficiency of the robot.Keywords: Transmission line inspection, line sleeve, transmission line inspection robot, line sleeve inspection
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22777232 An Assessment of the Effects of Microbial Products on the Specific Oxygen Uptake in Submerged Membrane Bioreactor
Authors: M. F. R. Zuthi, H. H. Ngo, W. S. Guo, S. S. Chen, N. C. Nguyen, L. J. Deng, T. D. C. Tran
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Sustaining a desired rate of oxygen transfer for microbial activity is a matter of major concern for biological wastewater treatment (MBR). The study reported in the paper was aimed at assessing the effects of microbial products on the specific oxygen uptake rate (SOUR) in a conventional membrane bioreactor (CMBR) and that in a sponge submerged MBR (SSMBR). The production and progressive accumulation of soluble microbial products (SMP) and bound-extracellular polymeric substances (bEPS) were affecting the SOUR of the microorganisms which varied at different stages of operation of the MBR systems depending on the variable concentrations of the SMP/bEPS. The effect of bEPS on the SOUR was stronger in the SSMBR compared to that of the SMP, while relative high concentrations of SMP had adverse effects on the SOUR of the CMBR system. Of the different mathematical correlations analyzed in the study, logarithmic mathematical correlations could be established between SOUR and bEPS in SSMBR, and similar correlations could also be found between SOUR and SMP concentrations in the CMBR.
Keywords: Microbial products, Microbial activity, Specific oxygen uptake rate, Membrane bioreactor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18887231 Unsteady Transient Free Convective Flow of an Incompressible Viscous Fluid under Influence of Uniform Transverse Magnetic Field
Authors: Praveen Saraswat, Vipin Kumar Verma, Rudraman Singh
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The unsteady transient free convection flow of an incompressible dissipative viscous fluid between parallel plates at different distances have been investigated under porous medium. Due to presence of heat flux under the influence of uniform transverse magnetic field the velocity distribution and the temperature distribution, is shown graphically. Since exact solution is not possible so we find parametrical solution by perturbation technique. The result is shown in graph for different parameters. We notice that heat generation effects fluid velocity keeping in which of free convection which cools.
Keywords: Transient, Convection, MHD, Viscous, Porous.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14917230 Modeling and Simulating Human Arm Movement Using a 2 Dimensional 3 Segments Coupled Pendulum System
Authors: Loay A. Al-Zu'be, Asma A. Al-Tamimi, Thakir D. Al-Momani, Ayat J. Alkarala, Maryam A. Alzawahreh
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A two dimensional three segments coupled pendulum system that mathematically models human arm configuration was developed along with constructing and solving the equations of motions for this model using the energy (work) based approach of Lagrange. The equations of motion of the model were solved iteratively both as an initial value problem and as a two point boundary value problem. In the initial value problem solutions, both the initial system configuration (segment angles) and initial system velocity (segment angular velocities) were used as inputs, whereas, in the two point boundary value problem solutions initial and final configurations and time were used as inputs to solve for the trajectory of motion. The results suggest that the model solutions are sensitive to small changes in the dynamic forces applied to the system as well as to the initial and boundary conditions used. To overcome the system sensitivity a new approach is suggested.
Keywords: Body Configurations, Equations of Motion, Mathematical Modeling, Movement Trajectories.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21577229 Biodegradable Surfactants for Advanced Drug Delivery Strategies
Authors: C. Hönnscheidt, R. Krull
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Oxidative stress makes up common incidents in eukaryotic metabolism. The presence of diverse components disturbing the equilibrium during oxygen metabolism increases oxidative damage unspecifically in living cells. Body´s own ubiquinone (Q10) seems to be a promising drug in defending the heightened appearance of reactive oxygen species (ROS). Though, its lipophilic properties require a new strategy in drug formulation to overcome their low bioavailability. Consequently, the manufacture of heterogeneous nanodispersions is in focus for medical applications. The composition of conventional nanodispersions is made up of a drug-consisting core and a surfactive agent, also named as surfactant. Long-termed encapsulation of the surfactive components into tissues might be the consequence of the use during medical therapeutics. The potential of provoking side-effects is given by their nonbiodegradable properties. Further improvements during fabrication process use the incorporation of biodegradable components such as modified γ-polyglutamic acid which decreases the potential of prospective side-effects.
Keywords: Biopolymers, γ-Polyglutamic acid, Oxidative stress, Ubiquinone.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 22387228 Study on Planning of Smart GRID using Landscape Ecology
Authors: Sunglim Lee, Susumu Fujii, Koji Okamura
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Smart grid is a new approach for electric power grid that uses information and communications technology to control the electric power grid. Smart grid provides real-time control of the electric power grid, controlling the direction of power flow or time of the flow. Control devices are installed on the power lines of the electric power grid to implement smart grid. The number of the control devices should be determined, in relation with the area one control device covers and the cost associated with the control devices. One approach to determine the number of the control devices is to use the data on the surplus power generated by home solar generators. In current implementations, the surplus power is sent all the way to the power plant, which may cause power loss. To reduce the power loss, the surplus power may be sent to a control device and sent to where the power is needed from the control device. Under assumption that the control devices are installed on a lattice of equal size squares, our goal is to figure out the optimal spacing between the control devices, where the power sharing area (the area covered by one control device) is kept small to avoid power loss, and at the same time the power sharing area is big enough to have no surplus power wasted. To achieve this goal, a simulation using landscape ecology method is conducted on a sample area. First an aerial photograph of the land of interest is turned into a mosaic map where each area is colored according to the ratio of the amount of power production to the amount of power consumption in the area. The amount of power consumption is estimated according to the characteristics of the buildings in the area. The power production is calculated by the sum of the area of the roofs shown in the aerial photograph and assuming that solar panels are installed on all the roofs. The mosaic map is colored in three colors, each color representing producer, consumer, and neither. We started with a mosaic map with 100 m grid size, and the grid size is grown until there is no red grid. One control device is installed on each grid, so that the grid is the area which the control device covers. As the result of this simulation we got 350m as the optimal spacing between the control devices that makes effective use of the surplus power for the sample area.
Keywords: Landscape ecology, IT, smart grid, aerial photograph, simulation.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19677227 Interactive Shadow Play Animation System
Authors: Bo Wan, Xiu Wen, Lingling An, Xiaoling Ding
Abstract:
The paper describes a Chinese shadow play animation system based on Kinect. Users, without any professional training, can personally manipulate the shadow characters to finish a shadow play performance by their body actions and get a shadow play video through giving the record command to our system if they want. In our system, Kinect is responsible for capturing human movement and voice commands data. Gesture recognition module is used to control the change of the shadow play scenes. After packaging the data from Kinect and the recognition result from gesture recognition module, VRPN transmits them to the server-side. At last, the server-side uses the information to control the motion of shadow characters and video recording. This system not only achieves human-computer interaction, but also realizes the interaction between people. It brings an entertaining experience to users and easy to operate for all ages. Even more important is that the application background of Chinese shadow play embodies the protection of the art of shadow play animation.
Keywords: Gesture recognition, Kinect, shadow play animation, VRPN.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 27037226 Contamination of Organochlorine Pesticides in Nest Soil, Egg, and Blood of the Snail-eating Turtle (Malayemys macrocephala) from the Chao Phraya River Basin, Thailand
Authors: Sarun Keithmaleesatti, Pakorn Varanusupakul, Wattasit Siriwong, Kumthorn Thirakhupt, Mark Robson, Noppadon Kitana
Abstract:
Organochlorine pesticides (OCPs) are known to be persistent and bioaccumulative toxicants that may cause reproductive impairments in wildlife as well as human. The current study uses the snail-eating turtle Malayemys macrocephala, a long-lived animal commonly distribute in rice field habitat in central part of Thailand, as a sentinel to monitor OCP contamination in environment. The nest soil, complete clutch of eggs, and blood of the turtle were collected from agricultural areas in the Chao Phraya River Basin, Thailand during the nesting season of 2007-2008. The novel methods for tissue extraction by an accelerated solvent extractor (ASE, for egg) and liquid-liquid extraction (for blood) have been developed. The nineteen OCP residues were analyzed by gas chromatography with micro-electron captured detector (GC-μECD). The validated methods have met requirements of the AOAC standard. The results indicated that significant amounts of OCPs are still contaminated in nest soil and eggs of the turtle even though the OCPs had been banned in this area for many years. This suggested the potential risk to health of wildlife as well as human in the area.Keywords: Gas chromatography, persistent organic pollutants, rice field, sentinel species.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 18167225 The Effect of Biochar, Inoculated Biochar and Compost Biological Component of the Soil
Authors: H. Dvořáčková, I. Mikajlo, J. Záhora, J. Elbl
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Biochar can be produced from the waste matter and its application has been associated with returning of carbon in large amounts into the soil. The impacts of this material on physical and chemical properties of soil have been described. The biggest part of the research work is dedicated to the hypothesis of this material’s toxic effects on the soil life regarding its effect on the soil biological component. At present, it has been worked on methods which could eliminate these undesirable properties of biochar. One of the possibilities is to mix biochar with organic material, such as compost, or focusing on the natural processes acceleration in the soil. In the experiment has been used as the addition of compost as well as the elimination of toxic substances by promoting microbial activity in aerated water environment. Biochar was aerated for 7 days in a container with a volume of 20 l. This way modified biochar had six times higher biomass production and reduce mineral nitrogen leaching. Better results have been achieved by mixing biochar with compost.Keywords: Leaching of nitrogen, soil, biochar, compost.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 30317224 Hypersonic Flow of CO2-N2 Mixture around a Spacecraft during the Atmospheric Reentry
Authors: Zineddine Bouyahiaoui, Rabah Haoui
Abstract:
The aim of this work is to analyze a flow around the axisymmetric blunt body taken into account the chemical and vibrational nonequilibrium flow. This work concerns the entry of spacecraft in the atmosphere of the planet Mars. Since the equations involved are non-linear partial derivatives, the volume method is the only way to solve this problem. The choice of the mesh and the CFL is a condition for the convergence to have the stationary solution.Keywords: Hypersonic flow, nonequilibrium flow, shock wave, blunt body.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 926