Search results for: control of development
24174 An Optimal Hybrid EMS System for a Hyperloop Prototype Vehicle
Authors: J. F. Gonzalez-Rojo, Federico Lluesma-Rodriguez, Temoatzin Gonzalez
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Hyperloop, a new mode of transport, is gaining significance. It consists of the use of a ground-based transport system which includes a levitation system, that avoids rolling friction forces, and which has been covered with a tube, controlling the inner atmosphere lowering the aerodynamic drag forces. Thus, hyperloop is proposed as a solution to the current limitation on ground transportation. Rolling and aerodynamic problems, that limit large speeds for traditional high-speed rail or even maglev systems, are overcome using a hyperloop solution. Zeleros is one of the companies developing technology for hyperloop application worldwide. It is working on a concept that reduces the infrastructure cost and minimizes the power consumption as well as the losses associated with magnetic drag forces. For this purpose, Zeleros proposes a Hybrid ElectroMagnetic Suspension (EMS) for its prototype. In the present manuscript an active and optimal electromagnetic suspension levitation method based on nearly zero power consumption individual modules is presented. This system consists of several hybrid permanent magnet-coil levitation units that can be arranged along the vehicle. The proposed unit manages to redirect the magnetic field along a defined direction forming a magnetic circuit and minimizing the loses due to field dispersion. This is achieved using an electrical steel core. Each module can stabilize the gap distance using the coil current and either linear or non-linear control methods. The ratio between weight and levitation force for each unit is 1/10. In addition, the quotient between the lifted weight and power consumption at the target gap distance is 1/3 [kg/W]. One degree of freedom (DoF) (along the gap direction) is controlled by a single unit. However, when several units are present, a 5 DoF control (2 translational and 3 rotational) can be achieved, leading to the full attitude control of the vehicle. The proposed system has been successfully tested reaching TRL-4 in a laboratory test bench and is currently in TRL-5 state development if the module association in order to control 5 DoF is considered.Keywords: active optimal control, electromagnetic levitation, HEMS, high-speed transport, hyperloop
Procedia PDF Downloads 14724173 The Cost of Innovation in Software Development Projects
Authors: Mihai Liviu Despa
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The paper tackles the topic of determining the cost of innovation in software development projects. Innovation can be achieved either in a planned or unplanned manner. The paper approaches the scenarios were innovation is planned for. As a starting point an innovative software development project is analyzed. The project is depicted step by step as it was implemented, from inception to delivery. Costs that are proprietary to innovation in software development are isolated based on the author’s personal experience in managing the above mentioned project. Innovation costs components identified by the author are then validated using open discussions with software development professionals and projects managers on LinkedIn groups. In order to receive relevant feedback only groups that focus on software development and innovation management are targeted. Additional innovation cost components suggested by software development professionals and projects managers are also considered. Based on the identified cost components an indicator is built. The indicator is meant to formalize the process of determining the cost of innovation in a software development project. The indicator aggregates all the innovation cost components that are identified in the research process. The process of calculating each cost component is also described. Conclusions are formulated and new related research topics are submitted for debate.Keywords: innovation cost, IT project management, software development, innovation management
Procedia PDF Downloads 46124172 Estimation of the External Force for a Co-Manipulation Task Using the Drive Chain Robot
Authors: Sylvain Devie, Pierre-Philippe Robet, Yannick Aoustin, Maxime Gautier
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The aim of this paper is to show that the observation of the external effort and the sensor-less control of a system is limited by the mechanical system. First, the model of a one-joint robot with a prismatic joint is presented. Based on this model, two different procedures were performed in order to identify the mechanical parameters of the system and observe the external effort applied on it. Experiments have proven that the accuracy of the force observer, based on the DC motor current, is limited by the mechanics of the robot. The sensor-less control will be limited by the accuracy in estimation of the mechanical parameters and by the maximum static friction force, that is the minimum force which can be observed in this case. The consequence of this limitation is that industrial robots without specific design are not well adapted to perform sensor-less precision tasks. Finally, an efficient control law is presented for high effort applications.Keywords: control, identification, robot, co-manipulation, sensor-less
Procedia PDF Downloads 16124171 Changes in Some Biochemical Parameters and Body Weight of Chicken Exposed to Cadmium
Authors: Khaled Saeed Ali
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This study was conducted with 3 week old domestic chicken to determine the effect of supplementation of cadmium to dietary. 10 mg/kg Cadmium chloride added to maize- sesame cake meal diet for 4 weeks. The additional cadmium to the diet induced a decreasing body weight and changes in biochemical parameters of chicken. Chicken were divided into two groups. The first group was given a diet containing the concentration of 10 mg cadmium /kg daily for a period of 30 days and the second group was given diet without cadmium and used as a control group. The result revealed decrease in the body weight of treated chicken by 12.7 % compared to control group, whose body weight increased. The plasma glucose concentration, creatinine, aspartate aminotranseferase (AST), and alanine aminotransferase (ALT) were increased significantly (P<0.05) in Cd treated chicken in comparison to the control group. Cadmium accumulation was observed in the intestine, kidney, liver and bone. The accumulation of cadmium was markedly higher (3-4 times) in cadmium-treated animals compared to the control.Keywords: cadmium, biochemical parameters, body weight, chicken
Procedia PDF Downloads 47224170 Optimal Sliding Mode Controller for Knee Flexion during Walking
Authors: Gabriel Sitler, Yousef Sardahi, Asad Salem
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This paper presents an optimal and robust sliding mode controller (SMC) to regulate the position of the knee joint angle for patients suffering from knee injuries. The controller imitates the role of active orthoses that produce the joint torques required to overcome gravity and loading forces and regain natural human movements. To this end, a mathematical model of the shank, the lower part of the leg, is derived first and then used for the control system design and computer simulations. The design of the controller is carried out in optimal and multi-objective settings. Four objectives are considered: minimization of the control effort and tracking error; and maximization of the control signal smoothness and closed-loop system’s speed of response. Optimal solutions in terms of the Pareto set and its image, the Pareto front, are obtained. The results show that there are trade-offs among the design objectives and many optimal solutions from which the decision-maker can choose to implement. Also, computer simulations conducted at different points from the Pareto set and assuming knee squat movement demonstrate competing relationships among the design goals. In addition, the proposed control algorithm shows robustness in tracking a standard gait signal when accounting for uncertainty in the shank’s parameters.Keywords: optimal control, multi-objective optimization, sliding mode control, wearable knee exoskeletons
Procedia PDF Downloads 8224169 Hearing Conservation Program for Vector Control Workers: Short-Term Outcomes from a Cluster-Randomized Controlled Trial
Authors: Rama Krishna Supramanian, Marzuki Isahak, Noran Naqiah Hairi
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Noise-induced hearing loss (NIHL) is one of the highest recorded occupational diseases, despite being preventable. Hearing Conservation Program (HCP) is designed to protect workers hearing and prevent them from developing hearing impairment due to occupational noise exposures. However, there is still a lack of evidence regarding the effectiveness of this program. The purpose of this study was to determine the effectiveness of a Hearing Conservation Program (HCP) in preventing or reducing audiometric threshold changes among vector control workers. This study adopts a cluster randomized controlled trial study design, with district health offices as the unit of randomization. Nine district health offices were randomly selected and 183 vector control workers were randomized to intervention or control group. The intervention included a safety and health policy, noise exposure assessment, noise control, distribution of appropriate hearing protection devices, training and education program and audiometric testing. The control group only underwent audiometric testing. Audiometric threshold changes observed in the intervention group showed improvement in the hearing threshold level for all frequencies except 500 Hz and 8000 Hz for the left ear. The hearing threshold changes range from 1.4 dB to 5.2 dB with largest improvement at higher frequencies mainly 4000 Hz and 6000 Hz. Meanwhile for the right ear, the mean hearing threshold level remained similar at 4000 Hz and 6000 Hz after 3 months of intervention. The Hearing Conservation Program (HCP) is effective in preserving the hearing of vector control workers involved in fogging activity as well as increasing their knowledge, attitude and practice towards noise-induced hearing loss (NIHL).Keywords: adult, hearing conservation program, noise-induced hearing loss, vector control worker
Procedia PDF Downloads 17024168 An Approach to Control Electric Automotive Water Pumps Deploying Artificial Neural Networks
Authors: Gabriel S. Adesina, Ruixue Cheng, Geetika Aggarwal, Michael Short
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With the global shift towards sustainability and technological advancements, electric Hybrid vehicles (EHVs) are increasingly being seen as viable alternatives to traditional internal combustion (IC) engine vehicles, which also require efficient cooling systems. The electric Automotive Water Pump (AWP) has been introduced as an alternative to IC engine belt-driven pump systems. However, current control methods for AWPs typically employ fixed gain settings, which are not ideal for the varying conditions of dynamic vehicle environments, potentially leading to overheating issues. To overcome the limitations of fixed gain control, this paper proposes implementing an artificial neural network (ANN) for managing the AWP in EHVs. The proposed ANN provides an intelligent, adaptive control strategy that enhances the AWP's performance, supported through MATLAB simulation work illustrated in this paper. Comparative analysis demonstrates that the ANN-based controller surpasses conventional PID and fuzzy logic-based controllers (FLC), exhibiting no overshoot, 0.1secs rapid response, and 0.0696 IAE performance. Consequently, the findings suggest that ANNs can be effectively utilized in EHVs.Keywords: automotive water pump, cooling system, electric hybrid vehicles, artificial neural networks, PID control, fuzzy logic control, IAE, MATLAB
Procedia PDF Downloads 4124167 An Experimental Investigation of the Effect of Control Algorithm on the Energy Consumption and Temperature Distribution of a Household Refrigerator
Authors: G. Peker, Tolga N. Aynur, E. Tinar
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In order to determine the energy consumption level and cooling characteristics of a domestic refrigerator controlled with various cooling system algorithms, a side by side type (SBS) refrigerator was tested in temperature and humidity controlled chamber conditions. Two different control algorithms; so-called drop-in and frequency controlled variable capacity compressor algorithms, were tested on the same refrigerator. Refrigerator cooling characteristics were investigated for both cases and results were compared with each other. The most important comparison parameters between the two algorithms were taken as; temperature distribution, energy consumption, evaporation and condensation temperatures, and refrigerator run times. Standard energy consumption tests were carried out on the same appliance and resulted in almost the same energy consumption levels, with a difference of %1,5. By using these two different control algorithms, the power consumptions character/profile of the refrigerator was found to be similar. By following the associated energy measurement standard, the temperature values of the test packages were measured to be slightly higher for the frequency controlled algorithm compared to the drop-in algorithm. This paper contains the details of this experimental study conducted with different cooling control algorithms and compares the findings based on the same standard conditions.Keywords: control algorithm, cooling, energy consumption, refrigerator
Procedia PDF Downloads 37524166 Hybrid Dynamic Approach to Optimize the Impact of Shading Design and Control on Electrical Energy Demand
Authors: T. Parhizkar, H. Jafarian, F. Aramoun, Y. Saboohi
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Applying motorized shades have substantial effect on reducing energy consumption in building sector. Moreover, the combination of motorized shades with lighting systems and PV panels can lead to considerable reduction in the energy demand of buildings. In this paper, a model is developed to assess and find an optimum combination from shade designs, lighting control systems (dimming and on/off) and implementing PV panels in shades point of view. It is worth mentioning that annual saving for all designs is obtained during hourly simulation of lighting, solar heat flux and electricity generation with the use of PV panel. From 12 designs in general, three designs, two lighting control systems and PV panel option is implemented for a case study. The results illustrate that the optimum combination causes a saving potential of 792kW.hr per year.Keywords: motorized shades, daylight, cooling load, shade control, hourly simulation
Procedia PDF Downloads 17124165 Comparative Analysis of DTC Based Switched Reluctance Motor Drive Using Torque Equation and FEA Models
Authors: P. Srinivas, P. V. N. Prasad
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Since torque ripple is the main cause of noise and vibrations, the performance of Switched Reluctance Motor (SRM) can be improved by minimizing its torque ripple using a novel control technique called Direct Torque Control (DTC). In DTC technique, torque is controlled directly through control of magnitude of the flux and change in speed of the stator flux vector. The flux and torque are maintained within set hysteresis bands. The DTC of SRM is analysed by two methods. In one of the methods, the actual torque is computed by conducting Finite Element Analysis (FEA) on the design specifications of the motor. In the other method, the torque is computed by Simplified Torque Equation. The variation of peak current, average current, torque ripple and speed settling time with Simplified Torque Equation model is compared with FEA based model.Keywords: direct toque control, simplified torque equation, finite element analysis, torque ripple
Procedia PDF Downloads 47924164 Semi-Automatic Design and Fabrication of Water Waste Cleaning Machine
Authors: Chanida Tangjai Benchalak Muangmeesri, Dechrit Maneetham
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Collection of marine garbage in the modern world, where technology is vital to existence. Consequently, technology can assist in reducing the duplicate labor in the subject of collecting trash in the water that must be done the same way repeatedly owing to the consequence of suffering an emerging disease or COVID-19. This is due to the rapid advancement of technology. As a result, solid trash and plastic garbage are increasing. Agricultural gardens, canals, ponds, and water basins are all sources of water. Building boat-like instruments for rubbish collection in the water will be done this time. It has two control options, boat control via remote control and boat control via an Internet of Things system. A solar panel with a power output of 40 watts powers the system being able to store so accurate and precise waste collection, allowing for thorough water cleaning. The primary goals are to keep the water's surface clean and assess its quality to support the aquatic ecology.Keywords: automatic boat, water treatment, cleaning machine, iot
Procedia PDF Downloads 9124163 Efficiency of Treatment in Patients with Newly Diagnosed Destructive Pulmonary Tuberculosis Using Intravenous Chemotherapy
Authors: M. Kuzhko, M. Gumeniuk, D. Butov, T. Tlustova, O. Denysov, T. Sprynsian
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Background: The aim of the research was to determine the effectiveness of chemotherapy using intravenous antituberculosis drugs compared with their oral administration during the intensive phase of treatment. Methods: 152 tuberculosis patients were randomized into 2 groups: Main (n=65) who received isoniazid, ethambutol and sodium rifamycin intravenous + pyrazinamide per os and control (n=87) who received all the drugs (isoniazid, rifampicin, ethambutol, pyrazinamide) orally. Results: After 2 weeks of treatment symptoms of intoxication disappeared in 59 (90.7±3.59 %) of patients of the main group and 60 (68.9±4.9 %) patients in the control group, p<0.05. The mean duration of symptoms of intoxication in patients main group was 9.6±0.7 days, in control group – 13.7±0.9 days. After completing intensive phase sputum conversion was found in all the patients main group and 71 (81.6±4.1 %) patients control group p < 0.05. The average time of sputum conversion in main group was 1.6±0.1 months and 1.9±0.1 months in control group, p > 0.05. In patients with destructive pulmonary tuberculosis time to sputum conversion was 1.7±0.1 months in main group and 2.2±0.2 months in control group, p < 0.05. The average time of cavities healing in main group was 2.9±0.2 months and 3.9±0.2 months in the control group, p < 0.05. Conclusions: In patients with newly diagnosed destructive pulmonary tuberculosis use of isoniazid, ethambutol and sodium rifamycin intravenous in the intensive phase of chemotherapy resulted in a significant reduction in terms of the disappearance of symptoms of intoxication and sputum conversion.Keywords: intravenous chemotherapy, tuberculosis, treatment efficiency, tuberculosis drugs
Procedia PDF Downloads 20224162 Vibration Control of a Functionally Graded Carbon Nanotube-Reinforced Composites Beam Resting on Elastic Foundation
Authors: Gholamhosein Khosravi, Mohammad Azadi, Hamidreza Ghezavati
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In this paper, vibration of a nonlinear composite beam is analyzed and then an active controller is used to control the vibrations of the system. The beam is resting on a Winkler-Pasternak elastic foundation. The composite beam is reinforced by single walled carbon nanotubes. Using the rule of mixture, the material properties of functionally graded carbon nanotube-reinforced composites (FG-CNTRCs) are determined. The beam is cantilever and the free end of the beam is under follower force. Piezoelectric layers are attached to the both sides of the beam to control vibrations as sensors and actuators. The governing equations of the FG-CNTRC beam are derived based on Euler-Bernoulli beam theory Lagrange- Rayleigh-Ritz method. The simulation results are presented and the effects of some parameters on stability of the beam are analyzed.Keywords: carbon nanotubes, vibration control, piezoelectric layers, elastic foundation
Procedia PDF Downloads 27224161 Towards a Secure Storage in Cloud Computing
Authors: Mohamed Elkholy, Ahmed Elfatatry
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Cloud computing has emerged as a flexible computing paradigm that reshaped the Information Technology map. However, cloud computing brought about a number of security challenges as a result of the physical distribution of computational resources and the limited control that users have over the physical storage. This situation raises many security challenges for data integrity and confidentiality as well as authentication and access control. This work proposes a security mechanism for data integrity that allows a data owner to be aware of any modification that takes place to his data. The data integrity mechanism is integrated with an extended Kerberos authentication that ensures authorized access control. The proposed mechanism protects data confidentiality even if data are stored on an untrusted storage. The proposed mechanism has been evaluated against different types of attacks and proved its efficiency to protect cloud data storage from different malicious attacks.Keywords: access control, data integrity, data confidentiality, Kerberos authentication, cloud security
Procedia PDF Downloads 33524160 Development of an Instrument: The Contemporary Adolescent Well-Being Scale (CAWBS)
Authors: Camille Rault, Mark Bahr
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The aim of the present study was to develop a contemporaneous instrument measuring adolescent’s subjective well-being (SWB). The instrument development underwent a three-phase pilot study. Phase one (N = 31) used a qualitative approach to generate domains of SWB relevant to adolescents. During the second phase (N = 22), items were tested targeting these domains. Finally, the third phase (N = 22) assisted in addition, deletion and refinement according to the first two phases of the pilot. A total of 49 items were retained for the final version of the instrument. The Contemporary Adolescent Well-Being Scale (CAWBS) was administered to 1071 school children (599 girls) aged between ten to 18 years old (M = 14,70; SD = 1.45) from Queensland, Australia. Results confirmed the seven-factor construct hypothesized and explained 45% of the variance. The questionnaire pertained to seven domains of adolescent’s SWB, namely; Overall life satisfaction; Bullying; Body image; Social connectedness; Activities; Control appraisal; and Negative feelings. Reliability was shown to be acceptable with Cronbach’s alpha ranging from .58 to .89. Future research should refine the CAWBS and investigate the psychometric properties of this instrument.Keywords: adolescence, construct validity, instrument, subjective well-being
Procedia PDF Downloads 27024159 Detection of Pharmaceutical Personal Protective Equipment in Video Stream
Authors: Michael Leontiev, Danil Zhilikov, Dmitry Lobanov, Lenar Klimov, Vyacheslav Chertan, Daniel Bobrov, Vladislav Maslov, Vasilii Vologdin, Ksenia Balabaeva
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Pharmaceutical manufacturing is a complex process, where each stage requires a high level of safety and sterility. Personal Protective Equipment (PPE) is used for this purpose. Despite all the measures of control, the human factor (improper PPE wearing) causes numerous losses to human health and material property. This research proposes a solid computer vision system for ensuring safety in pharmaceutical laboratories. For this, we have tested a wide range of state-of-the-art object detection methods. Composing previously obtained results in this sphere with our own approach to this problem, we have reached a high accuracy ([email protected]) ranging from 0.77 up to 0.98 in detecting all the elements of a common set of PPE used in pharmaceutical laboratories. Our system is a step towards safe medicine production.Keywords: sterility and safety in pharmaceutical development, personal protective equipment, computer vision, object detection, monitoring in pharmaceutical development, PPE
Procedia PDF Downloads 8924158 Relationship among Teams' Information Processing Capacity and Performance in Information System Projects: The Effects of Uncertainty and Equivocality
Authors: Ouafa Sakka, Henri Barki, Louise Cote
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Uncertainty and equivocality are defined in the information processing literature as two task characteristics that require different information processing responses from managers. As uncertainty often stems from a lack of information, addressing it is thought to require the collection of additional data. On the other hand, as equivocality stems from ambiguity and a lack of understanding of the task at hand, addressing it is thought to require rich communication between those involved. Past research has provided weak to moderate empirical support to these hypotheses. The present study contributes to this literature by defining uncertainty and equivocality at the project level and investigating their moderating effects on the association between several project information processing constructs and project performance. The information processing constructs considered are the amount of information collected by the project team, and the richness and frequency of formal communications among the team members to discuss the project’s follow-up reports. Data on 93 information system development (ISD) project managers was collected in a questionnaire survey and analyzed it via the Fisher Test for correlation differences. The results indicate that the highest project performance levels were observed in projects characterized by high uncertainty and low equivocality in which project managers were provided with detailed and updated information on project costs and schedules. In addition, our findings show that information about user needs and technical aspects of the project is less useful to managing projects where uncertainty and equivocality are high. Further, while the strongest positive effect of interactive use of follow-up reports on performance occurred in projects where both uncertainty and equivocality levels were high, its weakest effect occurred when both of these were low.Keywords: uncertainty, equivocality, information processing model, management control systems, project control, interactive use, diagnostic use, information system development
Procedia PDF Downloads 29424157 Teacher Professional Development –Current Practices in a Secondary School in Brunei Darussalam
Authors: Shanthi Thomas
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This research paper presents the current practices of teacher professional development, perceived as beneficial by teachers themselves, in a private secondary school in Brunei Darussalam. This is part of the findings of a larger qualitative study on teacher empowerment, using ethnographic methods for data collection, i.e. participant observation, interviews and document analysis. The field work was carried out over a period of six months in 2013. An analysis of the field data revealed multiple pathways of teacher professional development existing in the school. The results indicate that school leaders, the teacher community in the school, students, and the teachers themselves were the agents in a school that facilitated teacher empowerment. Besides contributing to the knowledge base on teacher professional development, the results of this study provides directions for educational policy makers in their efforts to enhance professional development in secondary schools of similar characteristics. For school leaders and the teacher community, these findings offer guidelines for maximizing the opportunities for these professional development practices, by strengthening collegiality and by using the existing structures optimally for the benefit of all concerned.Keywords: colleagues and the wider teacher community, school leaders, self-driven professional development, teacher professional development
Procedia PDF Downloads 41324156 Retrofitted Semi-Active Suspension System for a Eelectric Model Vehicle
Authors: Shiuh-Jer Huang, Yun-Han Yeh
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A 40 steps manual adjusting shock absorber was refitted with DC motor driving mechanism to construct as a semi-active suspension system for a four-wheel drive electric vehicle. Accelerometer and potentiometer sensors are installed to measure the sprung mass acceleration and suspension system compression or rebound states for control purpose. A fuzzy logic controller was designed to derive appropriate damping target based on vehicle running condition for semi-active suspension system to follow. The damping ratio control of each wheel axis suspension system is executed with a robust fuzzy sliding mode controller (FSMC). Different road surface conditions are chosen to evaluate the control performance of this semi-active suspension system based on wheel axis acceleration signal.Keywords: semi-active suspension, electric vehicle, fuzzy sliding mode control, accelerometer
Procedia PDF Downloads 48124155 The Effect of Intimate Partner Violence on Child Abuse in South Korea: Focused on the Moderating Effects of Patriarchal Attitude and Informal Social Control
Authors: Hye Lin Yang, Clifton R. Emery
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Purpose: The purpose of this study is to examine the effects of intimate partner violence on child abuse, whether patriarchal attitude and informal social control moderate the relationship between intimate partner violence and child abuse. This study was conducted with data from The Seoul Families and Neighborhoods Study (SFNS). The SFNS is a representative random probability 3-stage cluster sample of 541 cohabiting couples in Seoul, South Korea collected in 2012. To verify research models, Random effect analysis were used. All analyses were performed using the Stata program. Results: Crucial findings are the following. First, intimate partner violence showed a significantly positive relationship with Child abuse. Second, there are significant moderating effects of informal social control on intimate partner violence - child abuse. Third, there are significant moderating effects of patriarchal attitude on intimate partner violence - child abuse. In other words, Patriarchal attitude is a significant risk factor of child abuse and informal social control is a significant Protection factor of child abuse. Based on results, the policy and practical implications for preventing child abuse, promoting informal social control were discussed.Keywords: Intimate partner violence, child abuse, informal social control, patriarchal attitude
Procedia PDF Downloads 30224154 A Controlled Mathematical Model for Population Dynamics in an Infested Honeybees Colonies
Authors: Chakib Jerry, Mounir Jerry
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In this paper, a mathematical model of infested honey bees colonies is formulated in order to investigate Colony Collapse Disorder in a honeybee colony. CCD, as it is known, is a major problem on honeybee farms because of the massive decline in colony numbers. We introduce to the model a control variable which represents forager protection. We study the controlled model to derive conditions under which the bee colony can fight off epidemic. Secondly we study the problem of minimizing prevention cost under model’s dynamics constraints.Keywords: honey bee, disease transmission model, disease control honeybees, optimal control
Procedia PDF Downloads 42824153 Phenotypic and Genotypic Expression of Hylomma Anatolicum Ticks Silenced for Ferritin Genes through RNA Interference Technology
Authors: Muhammad Sohail Sajid, Mahvish Maqbool, Hafiz Muhammad Rizwan, Muhammad Saqib, Haroon Ahmad
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Ticks are blood-sucking ectoparasite that causes a decrease in production and economic losses and affects mammals, reptiles, and birds. Hyalomma anatolicum is the main vector for CCHF transmission and Pakistan has faced several outbreaks of CCHF in the recent past. Ferritin (fer)is a highly conserved molecule that is ubiquitous in most tick tissues and responsible for iron metabolism and storage. It was hypothesized that the development of acaricidal resistance and residual effects of commercially used acaricides could be controlled by using alternative control methods, including RNA interference. The current study aimed to evaluate the fer silencing effects on tick feeding, average body weight, egg mass index, and mortality. Ticks, collected through the standard collection protocols were further subjected to RNA isolation using the Trizol method. Commercially available kit procedures were followed for cDNA and dsRNA synthesis. The soaking/Immersion method was used for dsRNA delivery. Our findings have shown a 27% reduction in body weight of fer silenced group and showed a significant association of fer and body weight. Silencing of fer had a significant effect on the engorgement percentage (P= 0.0007), oviposition (P=0.008), egg mass (P= 0.004) and hatching (P= 0.001). The soaking method was used for dsRNA delivery and 15°C was found to be an optimum temperature for inducing gene silencing in ticks as at this temperature, maximum survivability after immersion was attained. This study along with previous studies, described that iron toxicity due to the silencing of fer could play an important role in the control of ticks and fer can be used as a potent candidate for vaccine development.Keywords: ticks, iron, ferritin, engorgement, oviposition, immersion, RNA interference
Procedia PDF Downloads 9724152 Circular Approximation by Trigonometric Bézier Curves
Authors: Maria Hussin, Malik Zawwar Hussain, Mubashrah Saddiqa
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We present a trigonometric scheme to approximate a circular arc with its two end points and two end tangents/unit tangents. A rational cubic trigonometric Bézier curve is constructed whose end control points are defined by the end points of the circular arc. Weight functions and the remaining control points of the cubic trigonometric Bézier curve are estimated by variational approach to reproduce a circular arc. The radius error is calculated and found less than the existing techniques.Keywords: control points, rational trigonometric Bézier curves, radius error, shape measure, weight functions
Procedia PDF Downloads 47724151 The Impact of a Sustainable Solar Heating System on the Growth of Strawberry Plants in an Agricultural Greenhouse
Authors: Ilham Ihoume, Rachid Tadili, Nora Arbaoui
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The use of solar energy is a crucial tactic in the agricultural industry's plan to decrease greenhouse gas emissions. This clean source of energy can greatly lower the sector's carbon footprint and make a significant impact in the fight against climate change. In this regard, this study examines the effects of a solar-based heating system, in a north-south oriented agricultural greenhouse on the development of strawberry plants during winter. This system relies on the circulation of water as a heat transfer fluid in a closed circuit installed on the greenhouse roof to store heat during the day and release it inside at night. A comparative experimental study was conducted in two greenhouses, one experimental with the solar heating system and the other for control without any heating system. Both greenhouses are located on the terrace of the Solar Energy and Environment Laboratory of the Mohammed V University in Rabat, Morocco. The developed heating system consists of a copper coil inserted in double glazing and placed on the roof of the greenhouse, a water pump circulator, a battery, and a photovoltaic solar panel to power the electrical components. This inexpensive and environmentally friendly system allows the greenhouse to be heated during the winter and improves its microclimate system. This improvement resulted in an increase in the air temperature inside the experimental greenhouse by 6 °C and 8 °C, and a reduction in its relative humidity by 23% and 35% compared to the control greenhouse and the ambient air, respectively, throughout the winter. For the agronomic performance, it was observed that the production was 17 days earlier than in the control greenhouse.Keywords: sustainability, thermal energy storage, solar energy, agriculture greenhouse
Procedia PDF Downloads 8924150 Contemplation on Non-Expensive Housing Conception by Stable Approach in Metropolises
Authors: Mahdieh Omranian, Mehran Ghanbari Motlagh
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As we know, today urban growth, development, and intelligent social evolutions have been proposed in metropolises and this matter extends urban life which can have negative items besides positive and strong items. Along with research on urban life desirable development, conditions should be provided to provide the possibility of human stable development and improvement social welfare. These conditions can reinforce social, economic, and political structures related to non-expensive housing. Demand for non-expensive housing is increasing regarding to population increase and incremental urbanizing process. Therefore, the present study by precise exploration on conceptions, challenges, and strategies, should achieve an endogenous pattern and improve housing condition by looking to instant development. Therefore, the general objective of this article recognizes the existed strategies in housing and achieving desirable conditions for all social classes by sustainable development.Keywords: housing strategies, infrastructure, metropolis, sustainable development
Procedia PDF Downloads 33624149 An Improved Method on Static Binary Analysis to Enhance the Context-Sensitive CFI
Authors: Qintao Shen, Lei Luo, Jun Ma, Jie Yu, Qingbo Wu, Yongqi Ma, Zhengji Liu
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Control Flow Integrity (CFI) is one of the most promising technique to defend Code-Reuse Attacks (CRAs). Traditional CFI Systems and recent Context-Sensitive CFI use coarse control flow graphs (CFGs) to analyze whether the control flow hijack occurs, left vast space for attackers at indirect call-sites. Coarse CFGs make it difficult to decide which target to execute at indirect control-flow transfers, and weaken the existing CFI systems actually. It is an unsolved problem to extract CFGs precisely and perfectly from binaries now. In this paper, we present an algorithm to get a more precise CFG from binaries. Parameters are analyzed at indirect call-sites and functions firstly. By comparing counts of parameters prepared before call-sites and consumed by functions, targets of indirect calls are reduced. Then the control flow would be more constrained at indirect call-sites in runtime. Combined with CCFI, we implement our policy. Experimental results on some popular programs show that our approach is efficient. Further analysis show that it can mitigate COOP and other advanced attacks.Keywords: contex-sensitive, CFI, binary analysis, code reuse attack
Procedia PDF Downloads 32324148 Role of Arbuscular Mycorrhiza in Heavy Metal Tolerance in Sweet Basil Plants
Authors: Aboul-Nasr Amal, Sabry Soraya, Sabra Mayada
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The effects of phosphorus amendments and arbuscular mycorrhizal (AM) fungi Glomus intraradices on the sweet basil (Ocimum basilicum L.), chemical composition and percent of volatile oil, and metal accumulation in plants and its availability in soil were investigated in field experiment at two seasons 2012 and 2013 under contaminated soil with Pb and Cu. The content of essential oil and shoot and root dry weights of sweet basil was increased by the application of mineral phosphorus as compared to control. Inoculation with AM fungi reduced the metal concentration in shoot, recording a lowest value of (33.24, 18.60 mg/kg) compared to the control (46.49, 23.46 mg/kg) for Pb and Cu, respectively. Availability of Pb and Cu in soil were decreased after cultivation in all treatments compared to control. However, metal root concentration increased with the inoculation, with highest values of (30.15, 39.25 mg/kg)compared to control (22.01, 33.57mg/kg) for Pb and Cu, respectively. The content of linalool and methyl chavicol in basil oil was significantly increased in all treatments compared to control. We can thus conclude that the AM-sweet basil symbiosis could be employed as an approach to bioremediate polluted soils and enhance the yield and maintain the quality of volatile oil of sweet basil plants.Keywords: arbuscular mycorrhizal fungus, heavy metals, sweet basil, oil composition
Procedia PDF Downloads 25324147 Flow Control Optimisation Using Vortex Generators in Turbine Blade
Authors: J. Karthik, G. Vinayagamurthy
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Aerodynamic flow control is achieved by interaction of flowing medium with corresponding structure so that its natural flow state is disturbed to delay the transition point. This paper explains the aerodynamic effect and optimized design of Vortex Generators on the turbine blade to achieve maximum flow control. The airfoil is chosen from NREL [National Renewable Energy Laboratory] S-series airfoil as they are characterized with good lift characteristics and lower noise. Vortex generators typically chosen are Ogival, Rectangular, Triangular and Tapered Fin shapes attached near leading edge. Vortex generators are typically distributed from the primary to tip of the blade section. The design wind speed is taken as 6m/s and the computational analysis is executed. The blade surface is simulated using k- ɛ SST model and results are compared with X-FOIL results. The computational results are validated using Wind Tunnel Testing of the blade corresponding to the design speed. The effect of Vortex generators on the flow characteristics is studied from the results of analysis. By comparing the computational and test results of all shapes of Vortex generators; the optimized design is achieved for effective flow control corresponding to the blade.Keywords: flow control, vortex generators, design optimisation, CFD
Procedia PDF Downloads 40824146 Level of IGF-I and IGFBP-3 in Gingival Crevicular Fluid and Plasma in Patients with Aggressive Periodontitis
Authors: Youjeong Hwang
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Purpose: Insulin-like growth factor-I (IGF-I) promotes B-cell development, immunoglobulin formation, and interleukin-6 (IL-6) production, then regulate the immune response and inflammation. As IGF-I and their receptor also exist in the periodontal tissue, they may affect the immune response caused by periodontal pathogens in aggressive periodontitis (AgP) patients. The function of IGF is regulated by IGF binding proteins (IGFBPs), and IGFBP-3 is known to most abundant in plasma. The aim of the present study was to assess the concentration of IGF-I and IGFBP-3 in plasma and gingival crevicular fluid (GCF) in AgP patients and to find out their association. Methods: Nine patients with AgP (test group) and nine healthy subjects (control group) were included in this study. None of the subjects had a history of systemic disease, smoking or steroids medication. GCF samples were collected by microcapillary pipettes and plasma samples were obtained by venipuncture. Probing pocket depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were recorded. Samples were assayed for IGF-I and IGFBP-3 levels using ELISA. Results: Mean IGF-I level in GCF was higher in the test group than control. Mean IGF-I level in plasma and IGFBP-3 level in GCF and plasma in control group were higher than that of the test group. However, there was no statistical significance (p > 0.05). The mean level of IGF-I and IGFBP-3 in GCF was lower than those in plasma. Mean IGF-I level in plasma showed a negative correlation with PD and CAL (p < 0.05) in both groups. The levels of IGF-I and IGFBP-3 in GCF seemed to be negatively correlated with BOP in the test group (p < 0.05). Conclusions: The difference in the level of IGF-I and IGFBP-3 between AgP and healthy subjects was not significant. Further studies that explain the mechanism of the protective role of IGF-I with more samples are needed.Keywords: aggressive periodontitis, pathogenesis, insulin-like growth factor, insulin-like growth factor binding protein
Procedia PDF Downloads 21124145 Effects of Probiotics on Specific Immunity in Broiler Chicken in Syria
Authors: Moussa Majed, Omar Yaser
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The main objective of this experiment was to study the impact of Probiotic compound on the specific immunity as the case study of infectious bursal disease. Total of 8000 one-day old Ross 108 broiler were randomly divided into two experimental groups; control group (4500 birds) and experimental group (3500 birds). Birds in two groups were reared under similar environmental conditions. Birds in control group received basal diets without probiotic whereas the birds in experimental one were fed basal diets supplemented with a commercial probiotic mixture) probiotic lacting k, which contains bacteria cells beyond to lactobacillus, Streptococcus and bifidobacterium genus that are isolated from gut microflora in healthy chickens(. The commercial probiotic were used according to the manufacturer instruction. 400 blood samples for each group were collected from wing vein every 5-7 days as interval period till 42 days old. Indirect Enzyme-Linked Immunosorbent Assay (ELISA) test was performed to detect the level of infectious bursal disease virus (IBDV) antibodies. The results clearly showed that the mean of immune titers was significantly (p= 0.03) higher in trail group than control one. The coefficient of variance percentages were 55% and 39% for control and trial groups respectively, this illustrates that homogeneity of immunity titers in the trail group was much better comparing with control group. The values of geometric means of titers in the control group and trial group were reported 3820 and 8133, respectively. The crude mortality rate in the experimental group was two times lower comparing with control group (14% and 28% respectively, p = 0.005Keywords: probiotic, broiler chicken, infectious bursal disease, immunity, ELISA test
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