Search results for: gene circuit design
4873 Management of Facial Nerve Palsy Following Physiotherapy
Authors: Bassam Band, Simon Freeman, Rohan Munir, Hisham Band
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Objective: To determine efficacy of facial physiotherapy provided for patients with facial nerve palsy. Design: Retrospective study Subjects: 54 patients diagnosed with Facial nerve palsy were included in the study after they met the selection criteria including unilateral facial paralysis and start of therapy twelve months after the onset of facial nerve palsy. Interventions: Patients received the treatment offered at a facial physiotherapy clinic consisting of: Trophic electrical stimulation, surface electromyography with biofeedback, neuromuscular re-education and myofascial release. Main measures: The Sunnybrook facial grading scale was used to evaluate the severity of facial paralysis. Results: This study demonstrated the positive impact of physiotherapy for patient with facial nerve palsy with improvement of 24.2% on the Sunnybrook facial grading score from a mean baseline of 34.2% to 58.2%. The greatest improvement looking at different causes was seen in patient who had reconstructive surgery post Acoustic Neuroma at 31.3%. Conclusion: The therapy shows significant improvement for patients with facial nerve palsy even when started 12 months post onset of paralysis across different causes. This highlights the benefit of this non-invasive technique in managing facial nerve paralysis and possibly preventing the need for surgery.Keywords: facial nerve palsy, treatment, physiotherapy, bells palsy, acoustic neuroma, ramsey-hunt syndrome
Procedia PDF Downloads 5354872 Internet Pornography Consumption and Relationship Commitment of Filipino Married Individuals
Authors: Racidon P. Bernarte, Vincent Jude G. Estella, Dominador Jr. M. Nucon, Jin Danniel O. Villatema
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Purpose: Internet pornography has many negative effects, but one of the disturbing phases of pornography usage is; users are insentient on how pornography influences and affects them. The acceptance of Internet pornography use in a relationship has been found to be higher among men than among women. The use of pornography directly correlates to a decrease in sexual intimacy. Hence, this might lead to the weakening of the relationship of the married individuals to their partner. To find out the relevance of the claim, the researchers aimed to explore the relationship of Internet pornography consumption to the relationship commitment of married individuals in the Philippines. Different factors such as level of satisfaction, the size of the investment, quality of alternatives, relationship stability, and viewing habits of the Filipino married individuals were also considered in determining the relationship of watching pornography online and the relationship commitment of the Filipino married individuals. Design/ Methodology/ Approach –The study used the quantitative research approach, specifically descriptive method and correlation in order to further analyze the gathered data. A self-administered survey was distributed to 400 selected Filipino married individuals who were married individuals that are watching pornography on the Internet who are living in Quezon City. Findings –It is revealed that Internet pornography consumption has a negative effect on the relationship commitment of married individuals. Furthermore, watching pornography online weakened the relationship commitment of the Filipino married individuals that leads to an unstable relationship.Keywords: internet pornography consumption, relationship commitment, married individuals, polytechnic university of the Philippines
Procedia PDF Downloads 4184871 The Impact of Artificial Intelligence on Food Nutrition
Authors: Antonyous Fawzy Boshra Girgis
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Nutrition labels are diet-related health policies. They help individuals improve food-choice decisions and reduce intake of calories and unhealthy food elements, like cholesterol. However, many individuals do not pay attention to nutrition labels or fail to appropriately understand them. According to the literature, thinking and cognitive styles can have significant effects on attention to nutrition labels. According to the author's knowledge, the effect of global/local processing on attention to nutrition labels has not been previously studied. Global/local processing encourages individuals to attend to the whole/specific parts of an object and can have a significant impact on people's visual attention. In this study, this effect was examined with an experimental design using the eye-tracking technique. The research hypothesis was that individuals with local processing would pay more attention to nutrition labels, including nutrition tables and traffic lights. An experiment was designed with two conditions: global and local information processing. Forty participants were randomly assigned to either global or local conditions, and their processing style was manipulated accordingly. Results supported the hypothesis for nutrition tables but not for traffic lights.Keywords: nutrition, public health, SA Harvest, foodeye-tracking, nutrition labelling, global/local information processing, individual differencesmobile computing, cloud computing, nutrition label use, nutrition management, barcode scanning
Procedia PDF Downloads 404870 Electro-Thermo-Mechanical Behaviour of Functionally Graded Material Usage in Lead Acid Storage Batteries and the Benefits
Authors: Sandeep Das
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Terminal post is one of the most important features of a Battery. The design and manufacturing of post are very much critical especially when threaded inserts (Bolt-on type) are used since all the collected energy is delivered from the lead part to the threaded insert (Cu or Cu alloy). Any imperfection at the interface may cause Voltage drop, high resistance, high heat generation, etc. This may be because of sudden change of material properties from lead to Cu alloys. To avoid this problem, a scheme of material gradation is proposed for achieving continuous variation of material properties for the Post used in commercially available lead acid battery. The Functionally graded (FG) material for the post is considered to be composed of different layers of homogeneous material. The volume fraction of the materials used corresponding to each layer is calculated by considering its variation along the direction of current flow (z) according to a power law. Accordingly, the effective properties of the homogeneous layers are estimated and the Post composed of this FG material is modeled using the commercially available ANSYS software. The solid 186 layered structural solid element has been used for discretization of the model of the FG Post. A thermal electric analysis is performed on the layered FG model. The model developed has been validated by comparing the results of the existing Post model& experimental analysisKeywords: ANSYS, functionally graded material, lead-acid battery, terminal post
Procedia PDF Downloads 1394869 A New Instrumented Drop-Weight Test Machine for Studying the Impact Behaviour of Reinforced Concrete Beams
Authors: M. Al-Farttoosi, M. Y. Rafiq, J. Summerscales, C. Williams
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Structures can be subjected to impact loading from various sources like earthquake, tsunami, missiles and explosions. The impact loading can cause different degrees of damage to concrete structures. The demand for strengthening and rehabilitation of damaged structures is increasing. In recent years, Car0bon Fibre Reinforced Polymer (CFRP) matrix composites has gain more attention for strengthening and repairing these structures. To study the impact behaviour of the reinforced concrete (RC) beams strengthened or repaired using CFRP, a heavy impact test machine was designed and manufactured .The machine included a newly designed support system for beams together with various instrumentation. This paper describes the support design configuration of the impact test machine, instrumentation and dynamic analysis of the concrete beams. To evaluate the efficiency of the new impact test machine, experimental impact tests were conducted on simple supported reinforced concrete beam. Different methods were used to determine the impact force and impact response of the RC beams in terms of inertia force, maximum deflection, reaction force and fracture energy. The manufactured impact test machine was successfully used in testing RC beams under impact loading and used successfully to test the reinforced concrete beams strengthened or repaired using CFRP under impact loading.Keywords: beam, concrete, impact, machine
Procedia PDF Downloads 4234868 Designing of Efficient Polysulphide Reservoirs to Boost the Performance of Li-S Battery
Authors: Sarish Rehman, Kishwar Khan, Yanglong Hou
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Among the existed myriad energy-storage technologies, lithium–sulfur batteries (LSBs) show the appealing potential for the ubiquitous growth of next-generation electrical energy storage application, owing to their unparalleled theoretical energy density of 2600 Wh/kg that is over five times larger than that of conventional lithium-ion batteries (LIBs). Despite its significant advances, its large scale implementations are plagued by multitude issues: particularly the intrinsic insulating nature of the sulfur (10-30 S/cm), mechanical degradation of the cathode due to large volume changes of sulfur up to 80 % during cycling and loss of active material (producing polysulfide shuttle effect). We design a unique structure, namely silicon/silica (Si/SiO2) crosslink with hierarchical porous carbon spheres (Si/SiO2@C), and use it as a new and efficient sulfur host to prepare Si/SiO2@C-S hybrid spheres to solve the hurdle of the polysulfides dissolution. As results of intriguing structural advantages developed hybrids spheres, it acts as efficient polysulfides reservoir for enhancing lithium sulfur battery (LSB) in the terms of capacity, rate ability and cycling stability via combined chemical and physical effects.Keywords: high specific surface area, high power density, high content of sulfur, lithium sulfur battery
Procedia PDF Downloads 2274867 Various Factors Affecting Students Performances In A Saudi Medical School
Authors: Raneem O. Salem, Najwa Al-Mously, Nihal Mohamed Nabil, Abdulmohsen H. Al-Zalabani, Abeer F. Al-Dhawi, Nasser Al-Hamdan
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Objective: There are various demographic and educational factors that affect the academic performance of undergraduate medical students. The objective of this study is to identify these factors and correlate them to the GPA of the students. Methods: A cross-sectional study design utilizing grade point averages (GPAs) of two cohorts of students in both levels of the pre-clinical phase. In addition, self-administered questionnaire was used to evaluate the effect of these factors on students with poor and good cumulative GPA. Results: Among the various factors studied, gender, marital status, and the transportation used to reach the faculty significantly affected academic performance of students. Students with a cumulative GPA of 3.0 or greater significantly differed than those with a GPA of less than 3.0 being higher in female students, in married students, and type of transportation used to reach the college. Factors including age, educational factors, and type of transportation used have shown to create a significant difference in GPA between male and females. Conclusion: Factors such as age, gender, marital status, learning resources, study time, and the transportation used have been shown to significantly affect medical student GPA as a whole batch as well as when they are tested for gender.Keywords: academic performance, educational factors, learning resources, study time, gender, socio-demographic factors
Procedia PDF Downloads 2744866 Post-Exercise Effects of Cold Water Immersion over a 48-Hour Recovery Period on the Physical and Haematological Parameters of Male University-Level Rugby Players
Authors: Adele Broodryk, Cindy Pienaar, Martinique Sparks, Ben Coetzee
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Background: Cold water immersion (CWI) is a popular recovery modality utilised. However, discrepancies exist regarding the results over a 48 hour recovery period. Aim: To evaluate the effects of CWI and passive recovery (PAR) on a range of haematological and physical parameters over a 48-hour using a cross-sectional, pre-post-test design. Subjects and Methods: Both the and physical parameters were evaluated at baseline, after a 15-min fitness session, and at 0, 24 and 48 hours post-recovery in 23 male university rugby players. The CWI group sat in a cold water pool (8°C) for 20 min whereas the PAR group remained seated. Results: At 0 hours post-CWI, three (blood lactate (BLa-), Sodium (Na+) and haemoglobin) returned to baseline values, however Vertical Jump Test (VJT) height results decreased whereas after PAR it improved. From 0 to 24 and/or 48 h, four (Partial Oxygen (PO2) VJT-height, plasma glucose, and Na+) significantly increased (p ≤ 0.05) in either and/or both groups. Significant intergroup differences (p ≤ 0.05) were noticed in the physical tests. Conclusions: PAR is superior as an acute modality (0 hours) due to CWI cooling the body down. However, CWI demonstrates advantageous over a 24-hour period in a wide range of haematological variables.Keywords: cryotherapy, recuperation, haematological, rugby
Procedia PDF Downloads 2644865 A Human Factors Approach to Workload Optimization for On-Screen Review Tasks
Authors: Christina Kirsch, Adam Hatzigiannis
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Rail operators and maintainers worldwide are increasingly replacing walking patrols in the rail corridor with mechanized track patrols -essentially data capture on trains- and on-screen reviews of track infrastructure in centralized review facilities. The benefit is that infrastructure workers are less exposed to the dangers of the rail corridor. The impact is a significant change in work design from walking track sections and direct observation in the real world to sedentary jobs in the review facility reviewing captured data on screens. Defects in rail infrastructure can have catastrophic consequences. Reviewer performance regarding accuracy and efficiency of reviews within the available time frame is essential to ensure safety and operational performance. Rail operators must optimize workload and resource loading to transition to on-screen reviews successfully. Therefore, they need to know what workload assessment methodologies will provide reliable and valid data to optimize resourcing for on-screen reviews. This paper compares objective workload measures, including track difficulty ratings and review distance covered per hour, and subjective workload assessments (NASA TLX) and analyses the link between workload and reviewer performance, including sensitivity, precision, and overall accuracy. An experimental study was completed with eight on-screen reviewers, including infrastructure workers and engineers, reviewing track sections with different levels of track difficulty over nine days. Each day the reviewers completed four 90-minute sessions of on-screen inspection of the track infrastructure. Data regarding the speed of review (km/ hour), detected defects, false negatives, and false positives were collected. Additionally, all reviewers completed a subjective workload assessment (NASA TLX) after each 90-minute session and a short employee engagement survey at the end of the study period that captured impacts on job satisfaction and motivation. The results showed that objective measures for tracking difficulty align with subjective mental demand, temporal demand, effort, and frustration in the NASA TLX. Interestingly, review speed correlated with subjective assessments of physical and temporal demand, but to mental demand. Subjective performance ratings correlated with all accuracy measures and review speed. The results showed that subjective NASA TLX workload assessments accurately reflect objective workload. The analysis of the impact of workload on performance showed that subjective mental demand correlated with high precision -accurately detected defects, not false positives. Conversely, high temporal demand was negatively correlated with sensitivity and the percentage of detected existing defects. Review speed was significantly correlated with false negatives. With an increase in review speed, accuracy declined. On the other hand, review speed correlated with subjective performance assessments. Reviewers thought their performance was higher when they reviewed the track sections faster, despite the decline in accuracy. The study results were used to optimize resourcing and ensure that reviewers had enough time to review the allocated track sections to improve defect detection rates in accordance with the efficiency-thoroughness trade-off. Overall, the study showed the importance of a multi-method approach to workload assessment and optimization, combining subjective workload assessments with objective workload and performance measures to ensure that recommendations for work system optimization are evidence-based and reliable.Keywords: automation, efficiency-thoroughness trade-off, human factors, job design, NASA TLX, performance optimization, subjective workload assessment, workload analysis
Procedia PDF Downloads 1214864 Modeling of a UAV Longitudinal Dynamics through System Identification Technique
Authors: Asadullah I. Qazi, Mansoor Ahsan, Zahir Ashraf, Uzair Ahmad
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System identification of an Unmanned Aerial Vehicle (UAV), to acquire its mathematical model, is a significant step in the process of aircraft flight automation. The need for reliable mathematical model is an established requirement for autopilot design, flight simulator development, aircraft performance appraisal, analysis of aircraft modifications, preflight testing of prototype aircraft and investigation of fatigue life and stress distribution etc. This research is aimed at system identification of a fixed wing UAV by means of specifically designed flight experiment. The purposely designed flight maneuvers were performed on the UAV and aircraft states were recorded during these flights. Acquired data were preprocessed for noise filtering and bias removal followed by parameter estimation of longitudinal dynamics transfer functions using MATLAB system identification toolbox. Black box identification based transfer function models, in response to elevator and throttle inputs, were estimated using least square error technique. The identification results show a high confidence level and goodness of fit between the estimated model and actual aircraft response.Keywords: fixed wing UAV, system identification, black box modeling, longitudinal dynamics, least square error
Procedia PDF Downloads 3254863 Seismic Fragility of Base-Isolated Multi-Story Piping System in Critical Facilities
Authors: Bu Seog Ju, Ho Young Son, Yong Hee Ryu
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This study is focused on the evaluation of seismic fragility of multi-story piping system installed in critical structures, isolated with triple friction pendulum bearing. The concept of this study is to isolate the critical building structure as well as nonstructural component, especially piping system in order to mitigate the earthquake damage and achieve the reliable seismic design. Then, the building system and multi-story piping system was modeled in OpenSees. In particular, the triple friction pendulum isolator was accounted for the vertical and horizontal coupling behavior in the building system subjected to seismic ground motions. Consequently, in order to generate the seismic fragility of base-isolated multi-story piping system, 21 selected seismic ground motions were carried out, by using Monte Carlo Simulation accounted for the uncertainties in demand. Finally, the system-level fragility curves corresponding to the limit state of the piping system was conducted at each T-joint system, which was commonly failure points in piping systems during and after an earthquake. Additionally, the system-level fragilities were performed to the first floor and second floor level in critical structures.Keywords: fragility, friction pendulum bearing, nonstructural component, seismic
Procedia PDF Downloads 1504862 An Improved Convolution Deep Learning Model for Predicting Trip Mode Scheduling
Authors: Amin Nezarat, Naeime Seifadini
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Trip mode selection is a behavioral characteristic of passengers with immense importance for travel demand analysis, transportation planning, and traffic management. Identification of trip mode distribution will allow transportation authorities to adopt appropriate strategies to reduce travel time, traffic and air pollution. The majority of existing trip mode inference models operate based on human selected features and traditional machine learning algorithms. However, human selected features are sensitive to changes in traffic and environmental conditions and susceptible to personal biases, which can make them inefficient. One way to overcome these problems is to use neural networks capable of extracting high-level features from raw input. In this study, the convolutional neural network (CNN) architecture is used to predict the trip mode distribution based on raw GPS trajectory data. The key innovation of this paper is the design of the layout of the input layer of CNN as well as normalization operation, in a way that is not only compatible with the CNN architecture but can also represent the fundamental features of motion including speed, acceleration, jerk, and Bearing rate. The highest prediction accuracy achieved with the proposed configuration for the convolutional neural network with batch normalization is 85.26%.Keywords: predicting, deep learning, neural network, urban trip
Procedia PDF Downloads 1384861 A Comprehensive Review on the Effect of Corporal Punishment and Development of Defence Styles and Fear of Intimacy
Authors: Sandra Sasikumar, Noorjahan AI, Aurine Anthony
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The background of this article is the frequently unacknowledged effects of corporal punishment in a child's life as they change into adulthood, how it may permutate into various dynamics and combinations and manifest in major areas like fear of intimacy and reactive and ineffective defending styles, which may eventually lead to much more interpersonal problems and in extreme cases psychopathology. Even though such studies require a longitudinal research design, there is a wealth of information on corporal punishment in the literature. Defense styles, or the coping mechanisms that individuals use to deal with stress and difficult emotions, can also be affected by corporal punishment. Individuals who have experienced corporal punishment may develop maladaptive defense styles, such as repression or denial, that can make it difficult for them to process and cope with their emotions. The fear of intimacy, or the fear of getting close to others, is another potential effect of corporal punishment. Individuals who have experienced physical discipline may develop a fear of physical touch, making it difficult for them to form close relationships. This fear can also lead to other mental health issues, such as anxiety and depression. It is important to note that not everyone who experiences corporal punishment will develop these issues, and other factors can contribute to the development of these problems. However, corporal punishment can have a significant impact on an individual's mental and emotional well-being.Keywords: corporal punishment, fear of intimacy, defense styles, attachment
Procedia PDF Downloads 454860 Imparting Second Language Skill through M-Learning
Authors: Subramaniam Chandran, A. Geetha
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This paper addresses three issues: how to prepare instructional design for imparting English language skill from inter-disciplinary self-learning material; how the disadvantaged students are benefited from such kind of language skill imparted through m-learning; and how do the m-learners perform better than the other learners. This paper examines these issues through an experimental study conducted among the distance learners enrolled in preparatory program for bachelor’s degree. This program is designed for the disadvantage learners especially for the school drop-outs to qualify to pursue graduate program through distant education. It also explains how mobile learning helps them to enhance their capacity in learning despite their rural background and other disadvantages. In India nearly half of the students enrolled in schools do not complete their study. The pursuance of higher education is very low when compared with developed countries. This study finds a significant increase in their learning capacity and mobile learning seems to be a viable alternative where conventional system could not reach the disadvantaged learners. Improving the English language skill is one of the reasons for such kind of performance. Exercises framed from the relevant self-learning material for enhancing English language skill not only improves language skill but also widens the subject-knowledge. This paper explains these issues out of the study conducted among the disadvantaged learners.Keywords: English language skill, disadvantaged learners, distance education, m-learning
Procedia PDF Downloads 6664859 Influence of Different Light Levels in Amaryllis (Hippeastrum X hybridum Hort.) Development and Flowering
Authors: Regina Maria M. Castilho, Isabela M. Morita, Ana Carolina T. Malavolta, Maximiliano K. Pagliarini
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An essential factor for flower production is solar radiation, which is part of plant vital processes. As excess as shortage of light can harm the development of the culture leading to loss in product quality, Unfeasible or decreasing their commercial value. The objective of this research was to evaluate different light levels and their influence on Amaryllis (Hippeastrum X hybridum Hort.) development and flowering. The experiment was conducted at UNESP, São Paulo State, Brazil from August to October 2014. The bulbs were placed in black vases of 1.2 L filled with commercial substrate and divided into 4 different lighting environments (treatments): T1–greenhouse, T2–greenhouse with shade cloth (50%), T3–low lights indoor (until 500 lx) and T4–medium lights indoor (between 500–1000 lx). The used design was completely randomized with ten repetitions and three vessels (bulbs), totalling 30 vessels (bulbs) per treatment. The evaluated characteristics were: Chlorophyll content, number of leaves, length of leaf, number of simultaneous rods, rod length, rod diameter, number of flowers, flowers diameter, beginning of flowering and flowering duration. The results showed that in greenhouse provided Amaryllis better quality plants.Keywords: açucena, bulbs, light, ornamental plants
Procedia PDF Downloads 4544858 High Gain Mobile Base Station Antenna Using Curved Woodpile EBG Technique
Authors: P. Kamphikul, P. Krachodnok, R. Wongsan
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This paper presents the gain improvement of a sector antenna for mobile phone base station by using the new technique to enhance its gain for microstrip antenna (MSA) array without construction enlargement. The curved woodpile Electromagnetic Band Gap (EBG) has been utilized to improve the gain instead. The advantages of this proposed antenna are reducing the length of MSAs array but providing the higher gain and easy fabrication and installation. Moreover, it provides a fan-shaped radiation pattern, wide in the horizontal direction and relatively narrow in the vertical direction, which appropriate for mobile phone base station. The paper also presents the design procedures of a 1x8 MSAs array associated with U-shaped reflector for decreasing their back and side lobes. The fabricated curved woodpile EBG exhibits bandgap characteristics at 2.1 GHz and is utilized for realizing a resonant cavity of MSAs array. This idea has been verified by both the Computer Simulation Technology (CST) software and experimental results. As the results, the fabricated proposed antenna achieves a high gain of 20.3 dB and the half-power beam widths in the E- and H-plane of 36.8 and 8.7 degrees, respectively. Good qualitative agreement between measured and simulated results of the proposed antenna was obtained.Keywords: gain improvement, microstrip antenna array, electromagnetic band gap, base station
Procedia PDF Downloads 3114857 A Conceptual Framework for Assessing the Development of Health Information Systems Enterprise Architecture Interoperability
Authors: Prosper Tafadzwa Denhere, Ephias Ruhode, Munyaradzi Zhou
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Health Information Systems (HISs) interoperability is emerging to be the future of modern healthcare systems Enterprise Architecture (EA), where healthcare entities are seamlessly interconnected to share healthcare data. The reality that the healthcare industry has been characterised by an influx of fragmented stand-alone e-Health systems, which present challenges of healthcare information sharing across platforms, desires much attention for systems integration efforts. The lack of an EA conceptual framework resultantly crates the need for investigating an ideal solution to the objective of Health Information Systems interoperability development assessment. The study takes a qualitative exploratory approach through a design science research context. The research aims to study the various themes withdrawn from the literature that can help in the assessment of interoperable HISs development through a literature study. Themes derived from the study include HIS needs, HIS readiness, HIS constraints, and HIS technology integration elements and standards tied to the EA development architectural layers of The Open Group Architecture Framework (TOGAF) as an EA development methodology. Eventually, the themes were conceptualised into a framework reviewed by two experts. The essence of the study was to provide a framework within which interoperable EA of HISs should be developed.Keywords: enterprise architecture, eHealth, health information systems, interoperability
Procedia PDF Downloads 1054856 Cyclic NGR Peptide Anchored Block Co-Polymeric Nanoparticles as Dual Targeting Drug Delivery System for Solid Tumor Therapy
Authors: Madhu Gupta, G. P. Agrawa, Suresh P. Vyas
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Certain tumor cells overexpress a membrane-spanning molecule aminopeptidase N (CD13) isoform, which is the receptor for peptides containing the NGR motif. NGR-modified Docetaxel (DTX)-loaded PEG-b-PLGA polymeric nanoparticles (cNGR-DNB-NPs) were developed and evaluated for their in vitro potential in HT-1080 cell line. The cNGR-DNB-NPs containing particles were about 148 nm in diameter with spherical shape and high encapsulation efficiency. Cellular uptake was confirmed both qualitatively and quantitatively by Confocal Laser Scanning Microscopy (CLSM) and flow cytometry. Both quantitatively and qualitatively results confirmed the NGR conjugated nanoparticles revealed the higher uptake of nanoparticles by CD13-overexpressed tumor cells. Free NGR inhibited the cellular uptake of cNGR-DNB-NPs, revealing the mechanism of receptor mediated endocytosis. In vitro cytotoxicity studies demonstrated that cNGR-DNB-NPs, formulation was more cytotoxic than unconjugated one, which were consistent well with the observation of cellular uptake. Hence, the selective delivery of cNGR-DNB-NPs formulation in CD13-overexpressing tumors represents a potential approach for the design of nanocarrier-based dual targeted delivery systems for targeting the tumor cells and vasculature.Keywords: solid Tumor, docetaxel, targeting, NGR ligand
Procedia PDF Downloads 4824855 Application of Response Surface Methodology to Optimize the Thermal Conductivity Enhancement of a Hybrid Nanofluid
Authors: Aminreza Noghrehabadi, Mohammad Behbahani, Ali Pourabbasi
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In this experimental work, unlike conventional methods that mix two nanoparticles together, silver nanoparticles have been synthesized on the surface of graphene. In this research, the effect of adding modified graphene nanocomposite-silver nanoparticles to the base fluid (distilled water) was studied. Different transmission electron microscopy (TEM) and field emission scanning electron microscope (FESEM) techniques have been used to examine the surfaces and atomic structure of nanoparticles. An ultrasonic device has been used to disperse the nanocomposite in distilled water. Also, the thermal conductivity coefficient was measured by the transient hot wire method using the KD2-pro device. In addition, the thermal conductivity coefficient was measured in the temperature range of 30°C to 50°C, concentration of 10 ppm to 1000 ppm, and ultrasonic time of 2 minutes to 15 minutes. The results showed that with the increase of all three parameters of temperature, concentration and ultrasonic time, the percentage of increase in thermal conductivity will go up until reaching the optimal point, and after passing the optimal point, the percentage of increase in thermal conductivity will have a downward trend. To calculate the thermal conductivity of this nanofluid, a very accurate experimental equation has been obtained using Design Expert software.Keywords: thermal conductivity, nanofluids, enhancement, silver nano particle, optimal point
Procedia PDF Downloads 884854 Peformance of Bali Cattles Fed with Various Levels of Oil Palm Frond Ammoniated
Authors: Mardiati Zain, Ryanto Khasrad, I. Elihasridas, J. Juliantoni
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The research objective was to determine the productivity of cattle fed a complete ration with ammoniated based of oil palm-frond supplemented by Rumen Microbes Growth Factor (RMGF). The research used Randomized Block Design applying 4 rations as treatment and 4 groups cattle. The treatments were: A (60% oil palm frond ammoniated + 40% concentrate + RMGF); B (50% oil palm frond ammoniated + 50% concentrate + RMGF); C (40% oil palm frond ammoniated + 60% concentrate + RMGF); and D (30% oil palm frond ammoniated + 70% concentrate + RMGF). The measured parameters were dry matter (DM) and organic matter (OM) intake, daily weight gain (DWG), feed efficiency, total digestible nutrient (TDN), and digestibility of crude protein (CP), neutral detergent fiber (NDF), acid detergent fiber (ADF), cellulose, hemicellulose. Statistical analysis showed that the treatment had no significant effect (P > 0.05) on DM intake, OM intake, daily weight gain, feed efficiency, digestibility of DM, OM, CP, TDN, NDF, hemicellulose but had a highly significant effect (P < 0.01) on digestibility of ADF and cellulose. All treatments with different ratio (oil palm frond ammoniated: concentrate : RMGF) had no different effect on cattle productivities.Keywords: oil palm frond ammoniated, digestibility, rumen microba growth factor, Bali cattle
Procedia PDF Downloads 3854853 Fatigue Strength of S275 Mild Steel under Cyclic Loading
Authors: T. Aldeeb, M. Abduelmula
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This study examines the fatigue life of S275 mild steel at room temperature. Mechanical components can fail under cyclic loading during period of time, known as the fatigue phenomenon. In order to prevent fatigue induced failures, material behavior should be investigated to determine the endurance limit of the material for safe design and infinite life, thus leading to reducing the economic cost and loss in human lives. The fatigue behavior of S275 mild steel was studied and investigated. Specimens were prepared in accordance with ASTM E3-11, and fatigue tests of the specimen were conducted in accordance with ASTM E466-07 on a smooth plate, with a continuous radius between ends (hourglass-shaped plate). The method of fatigue testing was applied with constant load amplitude and constant frequency of 4 Hz with load ratio (Fully Reversal R= -1). Surface fractures of specimens were investigated using Scanning Electron Microscope (SEM). The experimental results were compared with the results of a Finite Element Analysis (FEA), using simulation software. The experiment results indicated that the endurance fatigue limit of S275 mild steel was 195.47 MPa.Keywords: fatigue strength, fatigue life, finite element analysis(FEA), S275 mild steel, scanning electron microscope (SEM)
Procedia PDF Downloads 1604852 The Students' Mathematical Competency and Attitude towards Mathematics Using the Trachtenberg Speed Math System
Authors: Marlone D. Severo
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A pre- and post-test quasi-experimental design was used to test the intervention of Trachtenberg Speed Math on the mathematical competency of sixty (60) matched-paired students with a poor performing grade in Mathematics from one of the biggest public national high school at the South of Metro Manila. Both control and experimental group were administered with the Attitude Towards Mathematics Inventory (ATMI) before the pretest were given and both group showed high dislike for Mathematics. Pretest showed a 53 percent accuracy for the control group and 51 percent for the experimental group using a 15-item long multiplication test without any aid of a computing device. The experimental group were taught how to use the Trachtenberg number-keys and techniques in multiplication between October 2014 to March 2015. Post-test showed an improvement in the experimental group with 96 percent accuracy for the control group and a dismal 57 percent for the control group in long-multiplication. Post-test ATMI were administered. The control group showed a great dislike towards Mathematics, while the experimental group showed a positive attitude towards the subject.Keywords: attitude towards mathematics, mathematical competency, number-keys, trachtenberg speed math
Procedia PDF Downloads 3674851 Daily Stand-up Meetings - Relationships with Psychological Safety and Well-being in Teams
Authors: Sarah Rietze, Hannes Zacher
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Daily stand-up meetings are the most commonly used method in agile teams. In daily stand-ups, team members gather to coordinate and align their efforts, typically for a predefined period of no more than 15 minutes. The primary purpose is to ask and answer the following three questions: What was accomplished yesterday? What will be done today? What obstacles are impeding my progress? Daily stand-ups aim to enhance communication, mutual understanding, and support within the team, as well as promote collective learning from mistakes through daily synchronization and transparency. The use of daily stand-ups is intended to positively influence psychological safety within teams, which is the belief that it is safe to show oneself and take personal risks. Two studies will be presented, which explore the relationships between daily stand-ups, psychological safety, and psychological well-being. In a first study, based on survey results (n = 318), we demonstrated that daily stand-ups have a positive indirect effect on job satisfaction and a negative indirect effect on turnover intention through their impact on psychological safety. In a second study, we investigate, using an experimental design, how the use of daily stand-ups in teams enhances psychological safety and well-being compared to a control group that does not use daily stand-ups. Psychological safety is considered one of the most crucial cultural factors for a sustainable, agile organization. Agile approaches, such as daily stand-ups, are a critical part of the evolving work environment and offer a proactive means to shape and foster psychological safety within teams.Keywords: occupational wellbeing, agile work practices, psychological safety, daily stand-ups
Procedia PDF Downloads 654850 Comprehensive Review of Ultralightweight Security Protocols
Authors: Prashansa Singh, Manjot Kaur, Rohit Bajaj
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The proliferation of wireless sensor networks and Internet of Things (IoT) devices in the quickly changing digital landscape has highlighted the urgent need for strong security solutions that can handle these systems’ limited resources. A key solution to this problem is the emergence of ultralightweight security protocols, which provide strong security features while respecting the strict computational, energy, and memory constraints imposed on these kinds of devices. This in-depth analysis explores the field of ultralightweight security protocols, offering a thorough examination of their evolution, salient features, and the particular security issues they resolve. We carefully examine and contrast different protocols, pointing out their advantages and disadvantages as well as the compromises between resource limitations and security resilience. We also study these protocols’ application domains, including the Internet of Things, RFID systems, and wireless sensor networks, to name a few. In addition, the review highlights recent developments and advancements in the field, pointing out new trends and possible avenues for future research. This paper aims to be a useful resource for researchers, practitioners, and developers, guiding the design and implementation of safe, effective, and scalable systems in the Internet of Things era by providing a comprehensive overview of ultralightweight security protocols.Keywords: wireless sensor network, machine-to-machine, MQTT broker, server, ultralightweight, TCP/IP
Procedia PDF Downloads 814849 Removal of Mixed Heavy Metals from Contaminated Clay Soils Using Pulsed Electrokinetic Process
Authors: Nuhu Dalhat Mu’azu, Abdullahi Usman, A. Bukhari, Muhammad Hussain Essa, Salihu Lukman
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Electrokinetic remediation process was employed for the removal of four (4) heavy metals (Cr, Cu, Hg and Pb) from contaminated clay and bentonite soils under pulsed current supply mode. The effects of voltage gradient, pulse duty cycle and bentonite/clay ratio on the simultaneous removal efficiencies of the heavy metals were investigated. A total of thirteen experiments were designed and conducted according to factorial design with each experiment allowed to continuously ran for 3 weeks. Results obtained showed that increase in bentonite ratio decreased the removal efficiency of the heavy metals with no significant effect on the energy consumption. Conversely, increase in both voltage gradient and pulse duty cycle increased the heavy metals removal efficiencies with increased in energy consumption. Additionally, increase in voltage gradient increased the electrical conductivity and the soil pH due to due to continuous refill and replacement of process fluids as they decomposed under the induced voltage gradient. Under different operating conditions, the maximum removal efficiencies obtained for Cr, Cu, Hg, and Pb were 21.87, 83.2, 62.4, 78.06 and 16.65% respectively.Keywords: clay, bentonite, soil remediation, mixed contaminants, heavy metals, and electrokinetic-adsorption
Procedia PDF Downloads 4324848 Light-Emitting Diode Assisted Synthesis of Ag@Fe3O4 Nanoparticles and Their Application in Magnetic and Photothermal Hyperthermia Therapy
Authors: Pei-Wen Lin, Ta-I Yang
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Cancer has been one of the leading causes of human death for centuries. Considerable effort has been devoted to developing new treatments to reduce and control cancers. Magnetic particle hyperthermia and near-infrared photothermal therapy are the promising strategies to treat cancers due to its effectiveness with only mild side effects. This study focused on synthesizing magnetic Ag@Fe3O4 nanoparticles applicable for both of magnetic hyperthermia and near-infrared photothermal therapy. The hydrophilic poly(diallyldimethylammonium chloride) polymer was utilized to prepare superparamagnetic Fe3O4 clusters and to promote silver nanoparticles grown on Fe3O4 surfaces, obtaining Ag@Fe3O4 nanoparticles. The morphology (shape and dimension) of Ag nanoparticles was subsequently tailored using commercial LED lights. Therefore, the resulting Ag@Fe3O4 nanoparticles can absorb specific wavelength of light ranging from 400 nm to 800 nm by adjusting the wavelength of LED lights and the free silver ions in reaction solution. Heating performance tests confirmed that the synthesized Ag@Fe3O4 nanoparticles show appreciable heating capability for both of magnetic particle hyperthermia and near-infrared photothermal therapy. The findings in this study could provide new ideas to design functional materials to treat cancers.Keywords: light-emitting diode assisted synthesis, magnetic particles, photothermal materials, hyperthermia
Procedia PDF Downloads 2844847 Utilization of an Object Oriented Tool to Perform Model-Based Safety Analysis According to Extended Failure System Models
Authors: Royia Soliman, Salma ElAnsary, Akram Amin Abdellatif, Florian Holzapfel
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Model-Based Safety Analysis (MBSA) is an approach in which the system and safety engineers share a common system model created using a model-based development process. The model can also be extended by the failure modes of the system components. There are two famous approaches for the addition of fault behaviors to system models. The first one is to enclose the failure into the system design directly. The second approach is to develop a fault model separately from the system model, thus combining both independent models for safety analysis. This paper introduces a hybrid approach of MBSA. The approach tries to use informal abstracted models to investigate failure behaviors. The approach will combine various concepts such as directed graph traversal, event lists and Constraint Satisfaction Problems (CSP). The approach is implemented using an Object Oriented programming language. The components are abstracted to its failure logic and relationships of connected components. The implemented approach is tested on various flight control systems, including electrical and multi-domain examples. The various tests are analyzed, and a comparison to different approaches is represented.Keywords: flight control systems, model based safety analysis, safety assessment analysis, system modelling
Procedia PDF Downloads 1644846 Enablers of Total Quality Management for Social Enterprises: A Study of UAE Social Organizations
Authors: Farhat Sultana
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Originality: TQM principles are considered the tools to enhance organizational performance for most organizations. The paper contributes to the literature on the social enterprise because social organizations are still far behind in implementing TQM as compared to other private, public, and nonprofit organizations. Study design: The study is based on the data and information provided by two case studies and one focus group of social enterprises. Purpose: The purpose of the study is to get a deep understating of TQM implementation and to recognize the enablers of TQM in social enterprises that enhance the organizational performance of social enterprises located in UAE. Findings: As per the findings of the study, key enablers of Total Quality management in the case enterprises are leadership support, strategic approach for quality, continuous improvement, process improvement, employee empowerment and customer focus practices, though some inhibitors for TQM implementation such as managerial structure for quality assurance and performance appraisal mechanism are also pointed out by the study. Research limitations: The study findings are only based on two case studies and one focus group, which is not enough to generalize the findings to all social organizations. Practical Implications: Identified TQM enablers can help management to implement TQM successfully in social enterprises. Social implications: The study provides enabling path for Social enterprises to implement TQM to seek quality output to build a better society.Keywords: TQM, social enterprise, enablers of TQM, UAE
Procedia PDF Downloads 1104845 Design, Development and Application of a Green Manure Fertilizer Based on Mucuna Pruriens (L.) in Pelletized Presentation
Authors: Andres Zuñiga Orozco
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Green manure fertilizers have special importance in the development of organic and sustainable agriculture as a substitute or complement to chemical fertilization. They have many advantages, but they have application limitations in greenhouse crops and in open field crops that have low growing size. On the other hand, the logistics of sowing, harvesting and applying have been difficult for producers to adopt. For this reason, a pelletized presentation was designed in conjunction with Trichoderma harzianum. The biopellet was applied in pineapple as the first experience, managing to improve carbon levels in the soil and some nutrients. Then it was applied to tomatoes where it was proven that, nutritionally, it is possible to nourish the crop up to day 60 only with the biopellet, improve carbon levels in soil and control the fungus Fusarium oxysporum. Subsequently, it was applied to coffee seedlings with an organo-mineral formulation. Here, the improvement in the growth and nutrition of the plants was notable, as well as the increase in the microbial activity of the soil. M. pruriens biopellets allow crops to be nourished, allow biocontrolers to be added, improve soil conditions to promote greater microbial activity, reincorporate carbon and CO2 into the soil, are easily applicable, allow dosing and have a favorable shelf-life. They can be applied to all types of crops, both in the greenhouse and in the field.Keywords: Mucuna pruriens, pellets, carbon, Trichoderma, Fusarium
Procedia PDF Downloads 594844 Health Satisfaction and Family Impact of Parents of Children with Cancer
Authors: Ekhlas Al Gamal, Tony Long
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The impact on the parents of caring for a child with cancer was intense and wide-ranging. A high level of distress and low level or resilience remains during treatment. Even completion of treatment can be a time of increased anxiety and stress for parents particularly with worries about recurrence or relapse. The purpose of this study to examine the associations between parental satisfactions with healthcare provided for their child and the impact of being a caregiver for a child with cancer. Methodology: A descriptive, correlational and cross-sectional design was employed using data from Arabic versions of self-report questionnaires which were administered to 113 parents with children with cancer in Jordan during 2015. Findings: the result indicated that Family relationship functioning was ranked as the highest (better functioning) domain while daily activities were ranked as the lowest (poorer functioning) domain. Parents were generally satisfied with the health care provided, but their emotional needs were not met adequately. Parents with better social functioning were more satisfied in all areas of healthcare satisfaction other than emotional needs and communication. Parents who had a child with more emotional and behavioural problems were more likely to experience a negative impact on the family and a poor level of family functioning. Conclusion and Significance: Nurses and other health care providers should emphasis on family centred approach rather than child centred approach.Keywords: parents, children, cancer, Jordan
Procedia PDF Downloads 340