Search results for: Policy Response
922 Impact of the Transport on the Urban Heat Island
Authors: L. Haddad, Z. Aouachria
Abstract:
The development of transport systems has negative impacts on the environment although it has beneficial effects on society. The car policy caused many problems such as: - the spectacular growth of fuel consumption hence the very vast increase in urban pollution, traffic congestion in certain places and at certain times, the increase in the number of accidents. The exhaust emissions from cars and weather conditions are the main factors that determine the level of pollution in urban atmosphere. These conditions lead to the phenomenon of heat transfer and radiation occurring between the air and the soil surface of any town. These exchanges give rise, in urban areas, to the effects of heat islands that correspond to the appearance of excess air temperature between the city and its surrounding space. In this object, we perform a numerical simulation of the plume generated by the cars exhaust gases and show that these gases form a screening effect above the urban city which cause the heat island in the presence of wind flow. This study allows us: 1. To understand the different mechanisms of interactions between these phenomena.2. To consider appropriate technical solutions to mitigate the effects of the heat island.Keywords: Atmospheric pollution, impact on the health, urban transport, heat island.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3002921 A Study of Recycle Materials to Develop for Auto Part
Authors: Sittichai Kaewkuekool, Vanchai Laemlaksakul
Abstract:
At the present, auto part industries have become higher challenge in strategy market. As this consequence, manufacturers need to have better response to customers in terms of quality, cost, and delivery time. Moreover, they need to have a good management in factory to comply with international standard maximum capacity and lower cost. This would lead companies to have to order standard part from aboard and become the major cost of inventory. The development of auto part research by recycling materials experiment is to compare the auto parts from recycle materials to international auto parts (CKD). Factors studied in this research were the recycle material ratios of PU-foam, felt, and fabric. Results of recycling materials were considered in terms of qualities and properties on the parameters such as weight, sound absorption, water absorption, tensile strength, elongation, and heat resistance with the CKD. The results were showed that recycling materials would be used to replace for the CKD.
Keywords: International auto parts, recycling materials.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2074920 Interspecific Variation in Heat Stress Tolerance and Oxidative Damage among 15 C3 Species
Authors: Wagdi S. Soliman, Shu-ichi Sugiyama
Abstract:
The C3 plants are frequently suffering from exposure to high temperature stress which limits the growth and yield of these plants. This study seeks to clarify the physiological mechanisms of heat tolerance in relation to oxidative stress in C3 species. Fifteen C3 species were exposed to prolonged moderately high temperature stress 36/30°C for 40 days in a growth chamber. Chlorophyll fluorescence (Fv/Fm) showed great difference among species at 40 days of the stress. The species showed decreases in Fv/Fm and increases in malondialdehyde (MDA) content under stress condition as well as negative correlation between Fv/Fm and MDA (r = -0.61*) at 40 days of the stress. Hydrogen peroxide (H2O2) content before and after stress in addition to its response under stress showed great differences among species. The results suggest that the difference in heat tolerance among C3 species is closely associated with the ability to suppress oxidative damage but not with the content of reactive oxygen species (ROS) which is regulated by complex network.Keywords: C3 species, Fv/Fm, heat stress, oxidative stress.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1756919 New Findings on the User’s Preferences about Data Visualization of Online Reviews
Authors: Elizabeth Simão Carvalho, Marcirio Silveira Chaves
Abstract:
The information visualization is still a knowledge field that lacks from a solid theory to support it and there is a myriad of existing methodologies and taxonomies that can be combined and adopted as guidelines. In this context, it is necessary to pre-evaluate as much as possible all the assumptions that are considered for its design and development. We present an exploratory study (n = 123) to detect the graphical preferences of travelers using accommodation portals of Web 2.0 (e.g. tripadvisor.com). We took into account some of the most relevant ground rules applied in the field to map visually data and design end-user interaction. Moreover, the evaluation process was completely data visualization oriented. We found out that people tend to refuse more advanced types of visualization and that a hybrid combination between radial graphs and stacked bars should be explored. In sum, this paper introduces new findings about the visual model and the cognitive response of users of accommodation booking websites.
Keywords: Information visualization, Data visualization, Visualization evaluation, Online reviews, Booking portal, Hotel booking.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1720918 Signal and Harmonic Analysis of a Compressor Blade for Identification of the Nonlinear Frequency Vibration
Authors: Farhad Asadi, Gholamhasan Payganeh
Abstract:
High-speed turbomachine can experience significant centrifugal and gas bending loads. As a result, the compressor blades must be able to resist high-frequency oscillations due to surge or stall condition in flow field dynamics. In this paper, vibration characteristics of the 6th stage blade compressor have been examined in detail with, using 3-D finite element (FE) methods. The primary aim of this article is to gain an understanding of nonlinear vibration induced in the blade against different loading conditions. The results indicate the nonlinear behavior of the blade as a result of the amplitude of resonances or material properties. Since one of the leading causes of turbine blade failure is high cycle fatigue, simulations were started by specifying the stress distribution in the blade due to the centrifugal rotation. Next, resonant frequencies and critical speeds of the blade were defined by modal analysis. Finally, the harmonic analysis was simulated on the blades.
Keywords: Nonlinear vibration, modal analysis, resonance, frequency response, compressor blade.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 614917 Assessment of the Energy Balance Method in the Case of Masonry Domes
Authors: M. M. Sadeghi, S. Vahdani
Abstract:
Masonry dome structures had been widely used for covering large spans in the past. The seismic assessment of these historical structures is very complicated due to the nonlinear behavior of the material, their rigidness, and special stability configuration. The assessment method based on energy balance concept, as well as the standard pushover analysis, is used to evaluate the effectiveness of these methods in the case of masonry dome structures. The Soltanieh dome building is used as an example to which two methods are applied. The performance points are given from superimposing the capacity, and demand curves in Acceleration Displacement Response Spectra (ADRS) and energy coordination are compared with the nonlinear time history analysis as the exact result. The results show a good agreement between the dynamic analysis and the energy balance method, but standard pushover method does not provide an acceptable estimation.
Keywords: Energy balance method, pushover analysis, time history analysis, masonry dome.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 837916 Highly Linear and Low Noise AMR Sensor Using Closed Loop and Signal-Chopped Architecture
Authors: N. Hadjigeorgiou, A. C. Tsalikidou, E. Hristoforou, P. P. Sotiriadis
Abstract:
During the last few decades, the continuously increasing demand for accurate and reliable magnetic measurements has paved the way for the development of different types of magnetic sensing systems as well as different measurement techniques. Sensor sensitivity and linearity, signal-to-noise ratio, measurement range, cross-talk between sensors in multi-sensor applications are only some of the aspects that have been examined in the past. In this paper, a fully analog closed loop system in order to optimize the performance of AMR sensors has been developed. The operation of the proposed system has been tested using a Helmholtz coil calibration setup in order to control both the amplitude and direction of magnetic field in the vicinity of the AMR sensor. Experimental testing indicated that improved linearity of sensor response, as well as low noise levels can be achieved, when the system is employed.
Keywords: AMR sensor, closed loop, memory effects, chopper, linearity improvement, sensitivity improvement, magnetic noise, electronic noise.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1182915 Near Perfect Reconstruction Quadrature Mirror Filter
Authors: A. Kumar, G. K. Singh, R. S. Anand
Abstract:
In this paper, various algorithms for designing quadrature mirror filter are reviewed and a new algorithm is presented for the design of near perfect reconstruction quadrature mirror filter bank. In the proposed algorithm, objective function is formulated using the perfect reconstruction condition or magnitude response condition of prototype filter at frequency (ω = 0.5π) in ideal condition. The cutoff frequency is iteratively changed to adjust the filters coefficients using optimization algorithm. The performances of the proposed algorithm are evaluated in term of computation time, reconstruction error and number of iterations. The design examples illustrate that the proposed algorithm is superior in term of peak reconstruction error, computation time, and number of iterations. The proposed algorithm is simple, easy to implement, and linear in nature.
Keywords: Aliasing cancellations filter bank, Filter banks, quadrature mirror filter (QMF), subband coding.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2531914 Investigation of Regional Differences in Strong Ground Motions for the Iranian Plateau
Authors: Farhad Sedaghati, Shahram Pezeshk
Abstract:
Regional variations in strong ground motions for the Iranian Plateau have been investigated by using a simple statistical method called Analysis of Variance (ANOVA). In this respect, a large database consisting of 1157 records occurring within the Iranian Plateau with moment magnitudes of greater than or equal to 5 and Joyner-Boore distances up to 200 km has been considered. Geometric averages of horizontal peak ground accelerations (PGA) as well as 5% damped linear elastic response spectral accelerations (SA) at periods of 0.2, 0.5, 1.0, and 2.0 sec are used as strong motion parameters. The initial database is divided into two different datasets, for Northern Iran (NI) and Central and Southern Iran (CSI). The comparison between strong ground motions of these two regions reveals that there is no evidence for significant differences; therefore, data from these two regions may be combined to estimate the unknown coefficients of attenuation relationships.
Keywords: ANOVA, attenuation relationships, Iranian Plateau, PGA, regional variation, SA, strong ground motion.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1296913 Evaluation of the Degree of the Sufficiency of Public Green Spaces as an Indicator of Urban Density in the Chubu Metropolitan Area in Japan
Authors: Kayoko Yamamoto
Abstract:
This study uses GIS (Geographic Information Systems) to conduct an evaluation of the degree of the sufficiency of public green spaces such as parks and urban green areas as an indicator of the density of metropolitan areas, in particular the Chubu metropolitan area, in Japan. To that end, it first grasps the distribution situation of green spaces in the three metropolitan areas in Japan, especially in the Chubu metropolitan area, using GIS digital maps. And based on this result, it conducts a GIS evaluation of the degree of sufficiency of public green spaces and arranges the result for every distance belt from the central part to compare and exam for every distance belt away from the center in the Chubu metropolitan area. Furthermore, after pointing out the insufficient areas of public green spaces based on the result, it also proposes the improvement policy which can be introduced in the Chubu metropolitan area.Keywords: Public Green Spaces, Urban Density, MetropolitanAreas, Land Use, Urbanization, GIS (Geographic InformationSystems)
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2061912 Developing the Personal, Dissolving the Political
Authors: James Moir
Abstract:
The emergence of person-centred discourse based around notions of 'personal development planning- and 'work'life balance' has taken hold in education and the workplace in recent years. This paper examines this discourse with regard to recent developments in higher education as well as the inter-related issue of work-life balance in occupational careers. In both cases there have been national and trans-national policy initiatives directed towards improving both personal opportunities and competitive advantage in a global knowledge-based economy. However, despite an increasing concern with looking outward at this globalised educational and employment marketplace, there is something of a paradox in encouraging people to look inward at themselves in order to become more self-determined. This apparent paradox is considered from a discourse analytic perspective in terms of the ideological effects of an increasing concern with the personal world. Specifically, it is argued that there are tensions that emerge from a concern with an innerdirected process of self-reflection that dissolve any engagement with wider political issues that impact upon educational and career development.Keywords: Personal development planning, higher education, work-life balance, career.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1401911 Experimental Investigation and Constitutive Modeling of Volume Strain under Uniaxial Strain Rate Jump Test in HDPE
Authors: Rida B. Arieby, Hameed N. Hameed
Abstract:
In this work, tensile tests on high density polyethylene have been carried out under various constant strain rate and strain rate jump tests. The dependency of the true stress and specially the variation of volume strain have been investigated, the volume strain due to the phenomena of damage was determined in real time during the tests by an optical extensometer called Videotraction. A modified constitutive equations, including strain rate and damage effects, are proposed, such a model is based on a non-equilibrium thermodynamic approach called (DNLR). The ability of the model to predict the complex nonlinear response of this polymer is examined by comparing the model simulation with the available experimental data, which demonstrate that this model can represent the deformation behavior of the polymer reasonably well.
Keywords: Strain rate jump tests, Volume Strain, High Density Polyethylene, Large strain, Thermodynamics approach.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2123910 T-DOF PI Controller Design for a Speed Control of Induction Motor
Authors: Tianchai Suksri, Satean Tunyasrirut
Abstract:
This paper presents design and implements the T-DOF PI controller design for a speed control of induction motor. The voltage source inverter type space vector pulse width modulation technique is used the drive system. This scheme leads to be able to adjust the speed of the motor by control the frequency and amplitude of the input voltage. The ratio of input stator voltage to frequency should be kept constant. The T-DOF PI controller design by root locus technique is also introduced to the system for regulates and tracking speed response. The experimental results in testing the 120 watt induction motor from no-load condition to rated condition show the effectiveness of the proposed control scheme.Keywords: PI controller, root locus technique, space vector pulse width modulation, induction motor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2144909 Identification of Ductile Damage Parameters for Austenitic Steel
Authors: J. Dzugan, M. Spaniel, P. Konopík, J. Ruzicka, J. Kuzelka
Abstract:
The modeling of inelastic behavior of plastic materials requires measurements providing information on material response to different multiaxial loading conditions. Different triaxiality conditions and values of Lode parameters have to be covered for complex description of the material plastic behavior. Samples geometries providing material plastic behavoiur over the range of interest are proposed with the use of FEM analysis. Round samples with 3 different notches and smooth surface are used together with butterfly type of samples tested at angle ranging for 0 to 90°. Identification of ductile damage parameters is carried out on the basis of obtained experimental data for austenitic stainless steel. The obtained material plastic damage parameters are subsequently applied to FEM simulation of notched CT normally samples used for fracture mechanics testing and results from the simulation are compared with real tests.Keywords: baqus, austenitic steel, computer simulation, ductile damage, triaxiality
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3736908 Speed Sensorless Direct Torque Control of a PMSM Drive using Space Vector Modulation Based MRAS and Stator Resistance Estimator
Authors: A. Ameur, B. Mokhtari, N. Essounbouli, L. Mokrani
Abstract:
This paper presents a speed sensorless direct torque control scheme using space vector modulation (DTC-SVM) for permanent magnet synchronous motor (PMSM) drive based a Model Reference Adaptive System (MRAS) algorithm and stator resistance estimator. The MRAS is utilized to estimate speed and stator resistance and compensate the effects of parameter variation on stator resistance, which makes flux and torque estimation more accurate and insensitive to parameter variation. In other hand the use of SVM method reduces the torque ripple while achieving a good dynamic response. Simulation results are presented and show the effectiveness of the proposed method.Keywords: MRAS, PMSM, SVM, DTC, Speed and Resistance estimation, Sensorless drive
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3869907 Entrepreneurship Education as a 21st Century Strategy for Economic Growth and Sustainable Development
Authors: M. Fems Kurotimi, Agada Franklin, Godsave Aladei, Opigo Helen
Abstract:
Within the last 30 years, entrepreneurship education (EE) has continued to gain massive interest both in the field of research and among policy makers. This surge in interest can be attributed to the perceived importance EE plays in the equipping of potential entrepreneurs and as a 21st century strategy to foster economic growth and development. This paper sets out to ascertain the correlation between EE and economic growth and development. A desk research approach was adopted where a multiplicity of literatures in the field were studied intensely. The findings reveal that indeed EE has a positive effect on entrepreneurship engagement thereby fostering economic growth and development. However, some research studies reported the contrary. That although EE may be able to equip potential entrepreneurs with requisite entrepreneurial skills and competencies, it will only be successful in producing entrepreneurs if they are internally driven to become entrepreneurs, because we cannot make people what they are not. The findings also reveal that countries that adopted EE early have more innovations inspired by entrepreneurs and are more developed than those that only recently adopted EE as a viable tool for entrepreneurship and economic development.
Keywords: Entrepreneurship, entrepreneurship education, economic development, economic growth, sustainable development.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1760906 Citizens’ Perceptions towards e-Governance: Field Study
Authors: Alaa-Aldin Abdul Rahim A. Al Athmay
Abstract:
E-governance is an emerging and challenging initiative in developing countries. It is not only concerning the provision of services through the use ICT but rather entails building external interactions with citizen and businesses, enhancing democracy and trust of the political institutions of government. It embraces among other principles, openness, accountability and citizen engagement in public policy process. This study aims at finding users’ satisfaction with three chosen dimensions of e-governance, namely: openness, collaborative governance, and participation. These dimensions of e-governance are neither studied before in the context of Arab countries and nor explored earlier in relation to some demographics variables. A study of 900 users of e-government in United Arab Emirates (UAE) was undertaken to examine how gender, age, education, nationality, and employment affect their satisfaction with e-governance. Generally, satisfaction ratings vary significantly with these variables. However, the overall level of satisfaction with the three attributes was less favorable. Knowing the differences of citizen’s perceptions towards e-governance services would help policymakers in the design of effective e-governance strategy.
Keywords: E-governance, United Arab Emirates, Citizens' perceptions.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4616905 Structural Basis of Resistance of Helicobacterpylori DnaK to Antimicrobial Peptide Pyrrhocoricin
Authors: Musammat F. Nahar, Anna Roujeinikova
Abstract:
Bacterial molecular chaperone DnaK plays an essential role in protein folding, stress response and transmembrane targeting of proteins. DnaKs from many bacterial species, including Escherichia coli, Salmonella typhimurium and Haemophilus infleunzae are the molecular targets for the insect-derived antimicrobial peptide pyrrhocoricin. Pyrrhocoricin-like peptides bind in the substrate recognition tunnel. Despite the high degree of crossspecies sequence conservation in the substrate-binding tunnel, some bacteria are not sensitive to pyrrhocoricin. This work addresses the molecular mechanism of resistance of Helicobacter pylori DnaK to pyrrhocoricin. Homology modelling, structural and sequence analysis identify a single aminoacid substitution at the interface between the lid and the β-sandwich subdomains of the DnaK substrate-binding domain as the major determinant for its resistance.
Keywords: Helicobacter pylori, molecular chaperone DnaK, pyrrhocoricin, structural biology.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1749904 A Multiagent System for Distributed Systems Management
Authors: H. M. Kelash, H. M. Faheem, M. Amoon
Abstract:
The demand for autonomous resource management for distributed systems has increased in recent years. Distributed systems require an efficient and powerful communication mechanism between applications running on different hosts and networks. The use of mobile agent technology to distribute and delegate management tasks promises to overcome the scalability and flexibility limitations of the currently used centralized management approach. This work proposes a multiagent system that adopts mobile agents as a technology for tasks distribution, results collection, and management of resources in large-scale distributed systems. A new mobile agent-based approach for collecting results from distributed system elements is presented. The technique of artificial intelligence based on intelligent agents giving the system a proactive behavior. The presented results are based on a design example of an application operating in a mobile environment.Keywords: distributed management, distributed systems, efficiency, mobile agent, multiagent, response time
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2084903 The Use of Nuclear Generation to Provide Power System Stability
Authors: Heather Wyman-Pain, Yuankai Bian, Furong Li
Abstract:
The decreasing use of fossil fuel power stations has a negative effect on the stability of the electricity systems in many countries. Nuclear power stations have traditionally provided minimal ancillary services to support the system but this must change in the future as they replace fossil fuel generators. This paper explains the development of the four most popular reactor types still in regular operation across the world which have formed the basis for most reactor development since their commercialisation in the 1950s. The use of nuclear power in four countries with varying levels of capacity provided by nuclear generators is investigated, using the primary frequency response provided by generators as a measure for the electricity networks stability, to assess the need for nuclear generators to provide additional support as their share of the generation capacity increases.Keywords: Frequency control, nuclear power generation, power system stability, system inertia.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1514902 The Effect of Shear Wall Positions on the Seismic Response of Frame-Wall Structures
Authors: Anas M. Fares
Abstract:
The configuration of shear walls in plan of building will affect the seismic design of structure. The position of these walls will change the stiffness of each floor in the structure, the diaphragm center of mass displacement, and the drift of floor. Structural engineers preferred to distribute the walls in buildings to make the center of mass almost close enough to the center of rigidity, but to make this condition satisfied, they have many choices: construct the walls on the perimeter, or use intermediate walls, or use walls as core. In this paper and by using ETABS, each case is studied and compared to other cases according to three parameters: lateral stiffness, diaphragm displacement, and drift. It is found that the core walls are the best choice for the position of the walls in the buildings to resist earthquake loads.
Keywords: Lateral loads, lateral displacement, reinforced concrete, shear wall, seismic, ASCE7-16 code, ACI code, stiffness, drift.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1147901 Analytical Investigation of Replaceable Links with Reduced Web Section for Link-to-Column Connections in Eccentrically Braced Frames
Authors: Daniel Y. Abebe, Sijeong Jeong, Jaehyouk Choi
Abstract:
The use of eccentrically braced frame (EBF) is increasing day by day as EBF possesses high elastic stiffness, stable inelastic response under cyclic lateral loading, and excellent ductility and energy dissipation capacity. The ductility and energy dissipation capacity of EBF depends on the active link beams. Recently, there are two types EBFs; these are conventional EBFs and EBFs with replaceable links. The conventional EBF has a disadvantage during maintenance in post-earthquake. The concept of removable active link beam in EBF is developed to overcome the limitation of the conventional EBF in post-earthquake. In this study, a replaceable link with reduced web section is introduced and design equations are suggested. In addition, nonlinear finite element analysis was conducted in order to evaluate the proposed links.
Keywords: EBFs, replaceable link, earthquake disaster, reduced section.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1465900 Active Control of Multiferroic Composite Shells Using 1-3 Piezoelectric Composites
Authors: S. C. Kattimani
Abstract:
This article deals with the analysis of active constrained layer damping (ACLD) of smart multiferroic or magneto-electro-elastic doubly curved shells. The kinematics of deformations of the multiferroic doubly curved shell is described by a layer-wise shear deformation theory. A three-dimensional finite element model of multiferroic shells has been developed taking into account the electro-elastic and magneto-elastic couplings. A simple velocity feedback control law is employed to incorporate the active damping. Influence of layer stacking sequence and boundary conditions on the response of the multiferroic doubly curved shell has been studied. In addition, for the different orientation of the fibers of the constraining layer, the performance of the ACLD treatment has been studied.Keywords: Active constrained layer damping, doubly curved shells, magneto-electro-elastic, multiferroic composite, smart structures.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1039899 NFκB Pathway Modeling for Optimal Drug Combination Therapy on Multiple Myeloma
Authors: Huiming Peng, Jianguo Wen, Hongwei Li, Jeff Chang, Xiaobo Zhou
Abstract:
NFκB activation plays a crucial role in anti-apoptotic responses in response to the apoptotic signaling during tumor necrosis factor (TNFa) stimulation in Multiple Myeloma (MM). Although several drugs have been found effective for the treatment of MM by mainly inhibiting NFκB pathway, there are no any quantitative or qualitative results of comparison assessment on inhibition effect between different single drugs or drug combinations. Computational modeling is becoming increasingly indispensable for applied biological research mainly because it can provide strong quantitative predicting power. In this study, a novel computational pathway modeling approach is employed to comparably assess the inhibition effects of specific single drugs and drug combinations on the NFκB pathway in MM, especially the prediction of synergistic drug combinations.
Keywords: Computational modeling, drug combination, inhibition effect, multiple myeloma, NFkB pathway.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3047898 Frozen Fish: Control of Glazing Operation
Authors: Tânia Manso, Luís Teixeira, Paula M. Reis Correia
Abstract:
Glazing is a process used to reduce undesirable drying or dehydration of fish during frozen or cold storage. To evaluate the effect of the time/ temperature binomial of the cryogenic frozen tunnel in the amount of glazing watera Central Composite Rotatable Design was used, with application of the Response Surface Methodology. The results reveal that the time/ temperature obtained for pink cusk-eel in experimental conditions for glazing water are similar to the industrial process, but for red fish and merluza the industrial process needs some adjustments. Control charts were established and implementedto control the amount of glazing water on sardine and merluza. They show that the freezing process was statistically controlled but there were some tendencies that must be analyzed, since the trend of sample mean values approached either of the limits, mainly in merluza. Thus, appropriate actions must be taken, in order to improve the process.
Keywords: Control charts, frozen fish, glazing, RSM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 4452897 Design of Power System Stabilizer Based on Sliding Mode Control Theory for Multi- Machine Power System
Authors: Hossein Shahinzadeh, Ladan Darougaran, Ebrahim Jalili Sani, Hamed Yavari, Mahdi Mozaffari Legha
Abstract:
This paper present a new method for design of power system stabilizer (PSS) based on sliding mode control (SMC) technique. The control objective is to enhance stability and improve the dynamic response of the multi-machine power system. In order to test effectiveness of the proposed scheme, simulation will be carried out to analyze the small signal stability characteristics of the system about the steady state operating condition following the change in reference mechanical torque and also parameters uncertainties. For comparison, simulation of a conventional control PSS (lead-lag compensation type) will be carried out. The main approach is focusing on the control performance which later proven to have the degree of shorter reaching time and lower spike.Keywords: Power system stabilizer (PSS), multi-machine power system, sliding mode control
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2371896 The Nature of the Complicated Fabric Textures: How to Represent in Primary Visual Cortex
Authors: J. L. Liu, L. Wang, B. Zhu, J. Zhou, W. D. Gao
Abstract:
Fabric textures are very common in our daily life. However, the representation of fabric textures has never been explored from neuroscience view. Theoretical studies suggest that primary visual cortex (V1) uses a sparse code to efficiently represent natural images. However, how the simple cells in V1 encode the artificial textures is still a mystery. So, here we will take fabric texture as stimulus to study the response of independent component analysis that is established to model the receptive field of simple cells in V1. We choose 140 types of fabrics to get the classical fabric textures as materials. Experiment results indicate that the receptive fields of simple cells have obvious selectivity in orientation, frequency and phase when drifting gratings are used to determine their tuning properties. Additionally, the distribution of optimal orientation and frequency shows that the patch size selected from each original fabric image has a significant effect on the frequency selectivity.Keywords: Fabric Texture, Receptive Filed, Simple Cell, Spare Coding.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1474895 Transient Thermal Stresses of Functionally Graded Thick Hollow Cylinder under the Green-Lindsay Model
Authors: Tariq T. Darabseh
Abstract:
The transient thermoelastic response of thick hollow cylinder made of functionally graded material under thermal loading is studied. The generalized coupled thermoelasticity based on the Green-Lindsay model is used. The thermal and mechanical properties of the functionally graded material are assumed to be varied in the radial direction according to a power law variation as a function of the volume fractions of the constituents. The thermal and elastic governing equations are solved by using Galerkin finite element method. All the finite element calculations were done by using commercial finite element program FlexPDE. The transient temperature, radial displacement, and thermal stresses distribution through the radial direction of the cylinder are plotted.
Keywords: Finite element method, thermal stresses, Green-Lindsay theory, functionally graded material.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2005894 An Efficient Framework to Build Up Malware Dataset
Authors: Madihah Mohd Saudi, Zul Hilmi Abdullah
Abstract:
This research paper presents a framework on how to build up malware dataset.Many researchers took longer time to clean the dataset from any noise or to transform the dataset into a format that can be used straight away for testing. Therefore, this research is proposing a framework to help researchers to speed up the malware dataset cleaningprocesses which later can be used for testing. It is believed, an efficient malware dataset cleaning processes, can improved the quality of the data, thus help to improve the accuracy and the efficiency of the subsequent analysis. Apart from that, an in-depth understanding of the malware taxonomy is also important prior and during the dataset cleaning processes. A new Trojan classification has been proposed to complement this framework.This experiment has been conducted in a controlled lab environment and using the dataset from VxHeavens dataset. This framework is built based on the integration of static and dynamic analyses, incident response method and knowledge database discovery (KDD) processes.This framework can be used as the basis guideline for malware researchers in building malware dataset.
Keywords: Dataset, knowledge database discovery (KDD), malware, static and dynamic analyses.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3472893 ECA-SCTP: Enhanced Cooperative ACK for SCTP Path Recovery in Concurrent Multiple Transfer
Authors: GangHeok Kim, SungHoon Seo, JooSeok Song
Abstract:
Stream Control Transmission Protocol (SCTP) has been proposed to provide reliable transport of real-time communications. Due to its attractive features, such as multi-streaming and multihoming, the SCTP is often expected to be an alternative protocol for TCP and UDP. In the original SCTP standard, the secondary path is mainly regarded as a redundancy. Recently, most of researches have focused on extending the SCTP to enable a host to send its packets to a destination over multiple paths simultaneously. In order to transfer packets concurrently over the multiple paths, the SCTP should be well designed to avoid unnecessary fast retransmission and the mis-estimation of congestion window size through the paths. Therefore, we propose an Enhanced Cooperative ACK SCTP (ECASCTP) to improve the path recovery efficiency of multi-homed host which is under concurrent multiple transfer mode. We evaluated the performance of our proposed scheme using ns-2 simulation in terms of cwnd variation, path recovery time, and goodput. Our scheme provides better performance in lossy and path asymmetric networks.Keywords: SCTP, Concurrent Multiple Transfer, CooperativeSack, Dynamic ack policy
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1546