Search results for: Xinhua Zhang
792 Flow inside Micro-Channel Bounded by Superhydrophobic Surface with Eccentric Micro-Grooves
Authors: Yu Chen, Weiwei Ren, Xiaojing Mu, Feng Zhang, Yi Xu
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The superhydrophobic surface is widely used to reduce friction for the flow inside micro-channel and can be used to control/manipulate fluid, cells and even proteins in lab-on-chip. Fabricating micro grooves on hydrophobic surfaces is a common method to obtain such superhydrophobic surface. This study utilized the numerical method to investigate the effect of eccentric micro-grooves on the friction of flow inside micro-channel. A detailed parametric study was conducted to reveal how the eccentricity of micro-grooves affects the micro-channel flow under different grooves sizes, channel heights, Reynolds number. The results showed that the superhydrophobic surface with eccentric micro-grooves induces less friction than the counter part with aligning micro-grooves, which means requiring less power for pumps.Keywords: eccentricity, micro-channel, micro-grooves, superhydrophobic surface
Procedia PDF Downloads 331791 The LIP’s Electric Propulsion Development for Chinese Spacecraft
Authors: Zhang Tianping, Jia Yanhui, Li Juan, Yang Le, Yang Hao, Yang Wei, Sun Xiaojing, Shi Kai, Li Xingda, Sun Yunkui
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Lanzhou Institute of Physics (LIP) is the major supplier of electric propulsion subsystems for Chinese satellite platforms. The development statuses of these electric propulsion subsystems were summarized including the LIPS-200 ion electric propulsion subsystem (IEPS) for DFH-3B platform, the LIPS-300 IEPS for DFH-5 and DFH-4SP platform, the LIPS-200+ IEPS for DFH-4E platform and near-earth asteroid exploration spacecraft, the LIPS-100 IEPS for small satellite platform, the LHT-100 hall electric propulsion subsystem (HEPS) for flight test on XY-2 satellite, the LHT-140 HEPS for large LEO spacecraft, the LIPS-400 IEPS for deep space exploration mission and other EPS for other Chinese spacecraft.Keywords: ion electric propulsion, hall electric propulsion, satellite platform, LIP
Procedia PDF Downloads 728790 Optimal Location of the I/O Point in the Parking System
Authors: Jing Zhang, Jie Chen
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In this paper, we deal with the optimal I/O point location in an automated parking system. In this system, the S/R machine (storage and retrieve machine) travels independently in vertical and horizontal directions. Based on the characteristics of the parking system and the basic principle of AS/RS system (Automated Storage and Retrieval System), we obtain the continuous model in units of time. For the single command cycle using the randomized storage policy, we calculate the probability density function for the system travel time and thus we develop the travel time model. And we confirm that the travel time model shows a good performance by comparing with discrete case. Finally in this part, we establish the optimal model by minimizing the expected travel time model and it is shown that the optimal location of the I/O point is located at the middle of the left-hand above corner.Keywords: parking system, optimal location, response time, S/R machine
Procedia PDF Downloads 409789 DAG Design and Tradeoff for Full Live Virtual Machine Migration over XIA Network
Authors: Dalu Zhang, Xiang Jin, Dejiang Zhou, Jianpeng Wang, Haiying Jiang
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Traditional TCP/IP network is showing lots of shortages and research for future networks is becoming a hotspot. FIA (Future Internet Architecture) and FIA-NP (Next Phase) are supported by US NSF for future Internet designing. Moreover, virtual machine migration is a significant technique in cloud computing. As a network application, it should also be supported in XIA (expressive Internet Architecture), which is in both FIA and FIA-NP projects. This paper is an experimental study aims at verifying the feasibility of VM migration over XIA. We present three ways to maintain VM connectivity and communication states concerning DAG design and routing table modification. VM migration experiments are conducted intra-AD and inter-AD with KVM instances. The procedure is achieved by a migration control protocol which is suitable for the characters of XIA. Evaluation results show that our solutions can well supports full live VM migration over XIA network respectively, keeping services seamless.Keywords: DAG, downtime, virtual machine migration, XIA
Procedia PDF Downloads 855788 Development Contradictions and Planning Methods of Bicycles in Mountainous Cities: A Case Study of Chongqing
Authors: Chuhan Zhang
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As a typical mountainous city in the world, with the rise of shared transportation, cycling behavior in Chongqing is undergoing a role change from a traditional leisure activity to an important transportation mode. However, with the rapid increase in people's cycling demand, the built environment with mountainous features in Chongqing has become a key constraint hindering the further development of bicycle traffic. Based on the above background, the research summarizes the current development contradictions of bicycle traffic in Chongqing, analyses the global experience in the construction of bicycle-friendly cities with mountain characteristics, and combines the characteristics of bicycle traffic in Chongqing to further propose the planning method of the bicycle in mountain cities, to improve the bikability of Chongqing from the perspective of urban planning.Keywords: bicycle traffic, mountainous city, bicycle-friendly, bikability, Chongqing
Procedia PDF Downloads 99787 Piezoelectric based Passive Vibration Control of Composite Turbine Blade using Shunt Circuit
Authors: Kouider Bendine, Zouaoui Satla, Boukhoulda Farouk Benallel, Shun-Qi Zhang
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Turbine blades are subjected to a variety of loads, lead to an undesirable vibration. Such vibration can cause serious damages or even lead to a total failure of the blade. The present paper addresses the vibration control of turbine blade. The study aims to propose a passive vibration control using piezoelectric material. the passive control is effectuated by shunting an RL circuit to the piezoelectric patch in a parallel configuration. To this end, a Finite element model for the blade with the piezoelectric patch is implemented in ANSYS APDL. The model is then subjected to a harmonic frequency-based analysis for the case of control on and off. The results show that the proposed methodology was able to reduce blade vibration by 18%.Keywords: blade, active piezoelectric vibration control, finite element., shunt circuit
Procedia PDF Downloads 101786 Performance Analysis and Optimization for Diagonal Sparse Matrix-Vector Multiplication on Machine Learning Unit
Authors: Qiuyu Dai, Haochong Zhang, Xiangrong Liu
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Diagonal sparse matrix-vector multiplication is a well-studied topic in the fields of scientific computing and big data processing. However, when diagonal sparse matrices are stored in DIA format, there can be a significant number of padded zero elements and scattered points, which can lead to a degradation in the performance of the current DIA kernel. This can also lead to excessive consumption of computational and memory resources. In order to address these issues, the authors propose the DIA-Adaptive scheme and its kernel, which leverages the parallel instruction sets on MLU. The researchers analyze the effect of allocating a varying number of threads, clusters, and hardware architectures on the performance of SpMV using different formats. The experimental results indicate that the proposed DIA-Adaptive scheme performs well and offers excellent parallelism.Keywords: adaptive method, DIA, diagonal sparse matrices, MLU, sparse matrix-vector multiplication
Procedia PDF Downloads 134785 Multifunctional Composite Structural Elements for Sensing and Energy Harvesting
Authors: Amir H. Alavi, Kaveh Barri, Qianyun Zhang
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This study presents a new generation of lightweight and mechanically tunable structural composites with sensing and energy harvesting functionalities. This goal is achieved by integrating metamaterial and triboelectric energy harvesting concepts. Proof-of-concept polymeric beam prototypes are fabricated using 3D printing methods based on the proposed concept. Experiments and theoretical analyses are conducted to quantitatively investigate the mechanical and electrical properties of the designed multifunctional beams. The results show that these integrated structural elements can serve as nanogenerators and distributed sensing mediums without a need to incorporating any external sensing modules and electronics. The feasibility of design self-sensing and self-powering structural elements at multiscale for next generation infrastructure systems is further discussed.Keywords: multifunctional structures, composites, metamaterial, triboelectric nanogenerator, sensors, structural health monitoring, energy harvesting
Procedia PDF Downloads 196784 A Super-Efficiency Model for Evaluating Efficiency in the Presence of Time Lag Effect
Authors: Yanshuang Zhang, Byungho Jeong
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In many cases, there is a time lag between the consumption of inputs and the production of outputs. This time lag effect should be considered in evaluating the performance of organizations. Recently, a couple of DEA models were developed for considering time lag effect in efficiency evaluation of research activities. Multi-periods input(MpI) and Multi-periods output(MpO) models are integrated models to calculate simple efficiency considering time lag effect. However, these models can’t discriminate efficient DMUs because of the nature of basic DEA model in which efficiency scores are limited to ‘1’. That is, efficient DMUs can’t be discriminated because their efficiency scores are same. Thus, this paper suggests a super-efficiency model for efficiency evaluation under the consideration of time lag effect based on the MpO model. A case example using a long-term research project is given to compare the suggested model with the MpO model.Keywords: DEA, super-efficiency, time lag, multi-periods input
Procedia PDF Downloads 473783 Application of Blockchain Technology in Geological Field
Authors: Mengdi Zhang, Zhenji Gao, Ning Kang, Rongmei Liu
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Management and application of geological big data is an important part of China's national big data strategy. With the implementation of a national big data strategy, geological big data management becomes more and more critical. At present, there are still a lot of technology barriers as well as cognition chaos in many aspects of geological big data management and application, such as data sharing, intellectual property protection, and application technology. Therefore, it’s a key task to make better use of new technologies for deeper delving and wider application of geological big data. In this paper, we briefly introduce the basic principle of blockchain technology at the beginning and then make an analysis of the application dilemma of geological data. Based on the current analysis, we bring forward some feasible patterns and scenarios for the blockchain application in geological big data and put forward serval suggestions for future work in geological big data management.Keywords: blockchain, intellectual property protection, geological data, big data management
Procedia PDF Downloads 88782 Surface to the Deeper: A Universal Entity Alignment Approach Focusing on Surface Information
Authors: Zheng Baichuan, Li Shenghui, Li Bingqian, Zhang Ning, Chen Kai
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Entity alignment (EA) tasks in knowledge graphs often play a pivotal role in the integration of knowledge graphs, where structural differences often exist between the source and target graphs, such as the presence or absence of attribute information and the types of attribute information (text, timestamps, images, etc.). However, most current research efforts are focused on improving alignment accuracy, often along with an increased reliance on specific structures -a dependency that inevitably diminishes their practical value and causes difficulties when facing knowledge graph alignment tasks with varying structures. Therefore, we propose a universal knowledge graph alignment approach that only utilizes the common basic structures shared by knowledge graphs. We have demonstrated through experiments that our method achieves state-of-the-art performance in fair comparisons.Keywords: knowledge graph, entity alignment, transformer, deep learning
Procedia PDF Downloads 44781 Torque Magnetometry of Low Anisotropic CaCo2As2 Single Crystals
Authors: Kashif Nadeem, W. Zhang, X. G. Qiu
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Role of Co spins in CaCo2As2 single crystal is systematically studied by using dc magnetization and magnetic torque measurements. A spin-flop transition in the antiferromagnetism (AFM) CaCo2As2 single crystal is studied by using dc magnetization and magnetic torque. Field dependent and angle dependent torque magnetometry confirmed the existence of spin-flop transition in this compound which is in agreement with the dc magnetization studies. A comparison of dc magnetization and torque magnetometry measurements for CaCo2As2 single crystal is done in detail. In conclusion, torque magnetometry can be a useful tool to study the spin flop transition in low anisotropic compounds analogous to dc magnetization studies.Keywords: spin flop transition, torque magnetometry, magnetization, anisotropic
Procedia PDF Downloads 548780 A More Powerful Test Procedure for Multiple Hypothesis Testing
Authors: Shunpu Zhang
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We propose a new multiple test called the minPOP test for testing multiple hypotheses simultaneously. Under the assumption that the test statistics are independent, we show that the minPOP test has higher global power than the existing multiple testing methods. We further propose a stepwise multiple-testing procedure based on the minPOP test and two of its modified versions (the Double Truncated and Left Truncated minPOP tests). We show that these multiple tests have strong control of the family-wise error rate (FWER). A method for finding the p-values of the proposed tests after adjusting for multiplicity is also developed. Simulation results show that the Double Truncated and Left Truncated minPOP tests, in general, have a higher number of rejections than the existing multiple testing procedures.Keywords: multiple test, single-step procedure, stepwise procedure, p-value for multiple testing
Procedia PDF Downloads 83779 Attention Multiple Instance Learning for Cancer Tissue Classification in Digital Histopathology Images
Authors: Afaf Alharbi, Qianni Zhang
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The identification of malignant tissue in histopathological slides holds significant importance in both clinical settings and pathology research. This paper introduces a methodology aimed at automatically categorizing cancerous tissue through the utilization of a multiple-instance learning framework. This framework is specifically developed to acquire knowledge of the Bernoulli distribution of the bag label probability by employing neural networks. Furthermore, we put forward a neural network based permutation-invariant aggregation operator, equivalent to attention mechanisms, which is applied to the multi-instance learning network. Through empirical evaluation of an openly available colon cancer histopathology dataset, we provide evidence that our approach surpasses various conventional deep learning methods.Keywords: attention multiple instance learning, MIL and transfer learning, histopathological slides, cancer tissue classification
Procedia PDF Downloads 110778 Global Convergence of a Modified Three-Term Conjugate Gradient Algorithms
Authors: Belloufi Mohammed, Sellami Badreddine
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This paper deals with a new nonlinear modified three-term conjugate gradient algorithm for solving large-scale unstrained optimization problems. The search direction of the algorithms from this class has three terms and is computed as modifications of the classical conjugate gradient algorithms to satisfy both the descent and the conjugacy conditions. An example of three-term conjugate gradient algorithm from this class, as modifications of the classical and well known Hestenes and Stiefel or of the CG_DESCENT by Hager and Zhang conjugate gradient algorithms, satisfying both the descent and the conjugacy conditions is presented. Under mild conditions, we prove that the modified three-term conjugate gradient algorithm with Wolfe type line search is globally convergent. Preliminary numerical results show the proposed method is very promising.Keywords: unconstrained optimization, three-term conjugate gradient, sufficient descent property, line search
Procedia PDF Downloads 375777 Heterogenous Dimensional Super Resolution of 3D CT Scans Using Transformers
Authors: Helen Zhang
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Accurate segmentation of the airways from CT scans is crucial for early diagnosis of lung cancer. However, the existing airway segmentation algorithms often rely on thin-slice CT scans, which can be inconvenient and costly. This paper presents a set of machine learning-based 3D super-resolution algorithms along heterogeneous dimensions to improve the resolution of thicker CT scans to reduce the reliance on thin-slice scans. To evaluate the efficacy of the super-resolution algorithms, quantitative assessments using PSNR (Peak Signal to Noise Ratio) and SSIM (Structural SIMilarity index) were performed. The impact of super-resolution on airway segmentation accuracy is also studied. The proposed approach has the potential to make airway segmentation more accessible and affordable, thereby facilitating early diagnosis and treatment of lung cancer.Keywords: 3D super-resolution, airway segmentation, thin-slice CT scans, machine learning
Procedia PDF Downloads 117776 Mean Square Responses of a Cantilever Beam with Various Damping Mechanisms
Authors: Yaping Zhao, Yimin Zhang
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In the present paper, the stationary random vibration of a uniform cantilever beam is investigated. Two types of damping mechanism, i.e. the external and internal viscous dampings, are taken into account simultaneously. The excitation form is the support motion, and it is ideal white. Because two type of damping mechanism are considered concurrently, the product of the modal damping ratio and the natural frequency is not a constant anymore. As a result, the infinite definite integral encountered in the process of computing the mean square response is more complex than that in the existing literature. One signal progress of this work is to have calculated these definite integrals accurately. The precise solution of the mean square response is thus obtained in the infinite series form finally. Numerical examples are supplied and the numerical outcomes acquired confirm the validity of the theoretical analyses.Keywords: random vibration, cantilever beam, mean square response, white noise
Procedia PDF Downloads 384775 The Investigation and Analysis of Village Remains in Jinzhong Prefecture of Shanxi Province, China
Authors: Zhang Yu
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Shanxi Province is a province with a long history in China. The historical characteristics of Jinzhong Prefecture in Shaanxi Province are very prominent. This research has done a lot of field research and analysis, and has analyzed a large number of documents. The formation and characteristics of villages in Jinzhong Prefecture are summarized. But the remains of many areas have not been systematically discovered and analyzed. This study found that the reasons for the formation of villages are natural, cultural, traffic and economic reasons. It mainly includes water, mountain, and developed business culture during the Ming and Qing Dynasties. By analyzing the evolution characteristics of each period, the characteristics and remains of the existing villages are explained in detail. These types of relics mainly include courtyards, fortresses, and Exchange shops. This study can provide systematic guidance on the protection of future village remains.Keywords: Jinzhong Prefecture, village, features, remains
Procedia PDF Downloads 146774 Study on Fabrication of Surface Functional Micro and Nanostructures by Femtosecond Laser
Authors: Shengzhu Cao, Hui Zhou, Gan Wu, Lanxi Wanhg, Kaifeng Zhang, Rui Wang, Hu Wang
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The functional micro and nanostructures, which can endow material surface with unique properties such as super-absorptance, hydrophobic and drag reduction. Recently, femtosecond laser ablation has been demonstrated to be a promising technology for surface functional micro and nanostructures fabrication. In this paper, using femtosecond laser ablation processing technique, we fabricated functional micro and nanostructures on Ti and Al alloy surfaces, test results showed that processed surfaces have 82%~96% absorptance over a broad wavelength range from ultraviolet to infrared. The surface function properties, which determined by micro and nanostructures, could be modulated by variation laser parameters. These functional surfaces may find applications in such areas as photonics, plasmonics, spaceborne devices, thermal radiation sources, solar energy absorbers and biomedicine.Keywords: surface functional, micro and nanostructures, femtosecond laser, ablation
Procedia PDF Downloads 368773 Task Space Synchronization Control of Multi-Robot Arms with Position Synchronous Method
Authors: Zijian Zhang, Yangyang Dong
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Synchronization is of great importance to ensure the multi-arm robot to complete the task. Therefore, a synchronous controller is designed to coordinate task space motion of the multi-arm in the paper. The position error, the synchronous position error, and the coupling position error are all considered in the controller. Besides, an adaptive control method is used to adjust parameters of the controller to improve the effectiveness of coordinated control performance. Simulation in the Matlab shows the effectiveness of the method. At last, a robot experiment platform with two 7-DOF (Degree of Freedom) robot arms has been established and the synchronous controller simplified to control dual-arm robot has been validated on the experimental set-up. Experiment results show the position error decreased 10% and the corresponding frequency is also greatly improved.Keywords: synchronous control, space robot, task space control, multi-arm robot
Procedia PDF Downloads 165772 Optimization Design of Superposition Wave Form Automotive Exhaust Bellows Structure
Authors: Zhang Jianrun, He Tangling
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Superposition wave form automotive exhaust bellows is a new type of bellows, which has the characteristics of large compensation, good vibration isolation performance and long life. It has been paid more and more attention and applications in automotive exhaust pipe system. Aiming at the lack of current design methods of superposition wave form automotive exhaust bellows, this paper proposes a response surface parameter optimization method where the fatigue life and vibration transmissibility of the bellows are set as objectives. The parametric modeling of bellow structure is also adopted to achieve the high efficiency in the design. The approach proposed in this paper provides a new way for the design of superposition wave form automotive exhaust bellows. It embodies good engineering application value.Keywords: superposition wave form, exhaust bellows, optimization, vibration, fatigue life
Procedia PDF Downloads 96771 A Method for Modeling Flexible Manipulators: Transfer Matrix Method with Finite Segments
Authors: Haijie Li, Xuping Zhang
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This paper presents a computationally efficient method for the modeling of robot manipulators with flexible links and joints. This approach combines the Discrete Time Transfer Matrix Method with the Finite Segment Method, in which the flexible links are discretized by a number of rigid segments connected by torsion springs; and the flexibility of joints are modeled by torsion springs. The proposed method avoids the global dynamics and has the advantage of modeling non-uniform manipulators. Experiments and simulations of a single-link flexible manipulator are conducted for verifying the proposed methodologies. The simulations of a three-link robot arm with links and joints flexibility are also performed.Keywords: flexible manipulator, transfer matrix method, linearization, finite segment method
Procedia PDF Downloads 428770 Monitoring and Analysis of Bridge Crossing Ground Fissures
Authors: Zhiqing Zhang, Xiangong Zhou, Zihan Zhou
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Ground fissures can be seen in some cities all over the world. As a special urban geological disaster, ground fissures in Xi'an have caused great harm to infrastructure. Chang'an Road Interchange in Xi'an City is a bridge across ground fissures. The damage to Chang'an Road interchange is the most serious and typical. To study the influence of ground fissures on the bridge, we established a bridge monitoring system. The main monitoring items include elevation monitoring, structural displacement monitoring, etc. The monitoring results show that the typical failure is mainly reflected in the bridge deck damage caused by horizontal tension and vertical dislocation. For the construction of urban interchange spanning ground fissures, the interchange should be divided reasonably, a simple support structure with less restriction should be adopted, and the monitoring of supports should be strengthened to prevent the occurrence of beam falling.Keywords: bridge monitoring, ground fissures, typical disease, structural displacement
Procedia PDF Downloads 223769 A Resilience Process Model of Natural Gas Pipeline Systems
Authors: Zhaoming Yang, Qi Xiang, Qian He, Michael Havbro Faber, Enrico Zio, Huai Su, Jinjun Zhang
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Resilience is one of the key factors for system safety assessment and optimization, and resilience studies of natural gas pipeline systems (NGPS), especially in terms of process descriptions, are still being explored. Based on the three main stages, which are function loss process, recovery process, and waiting process, the paper has built functions and models which are according to the practical characteristics of NGPS and mainly analyzes the characteristics of deterministic interruptions. The resilience of NGPS also considers the threshold of the system function or users' satisfaction. The outcomes, which quantify the resilience of NGPS in different evaluation views, can be combined with the max flow and shortest path methods, help with the optimization of extra gas supplies and gas routes as well as pipeline maintenance strategies, the quick analysis of disturbance effects and the improvement of NGPS resilience evaluation accuracy.Keywords: natural gas pipeline system, resilience, process modeling, deterministic disturbance
Procedia PDF Downloads 126768 Investigating the Role of Circular RNA GATAD2A on H1N1 Replication
Authors: Tianqi Yu, Yingnan Ding, Yina Zhang, Yulan Liu, Yahui Li, Jing Lei, Jiyong Zhou, Suquan Song, Boli Hu
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Circular RNAs (circRNAs) play critical roles in various diseases. However, whether and how circular RNA regulates influenza A virus (IAV) infection is unknown. Here, we studied the role of circular RNA GATA Zinc Finger Domain Containing 2A (circ-GATAD2A) in the replication of IAV H1N1 in A549 cells. Circ-GATAD2A was formed upon H1N1 infection. Knockdown of circ-GATAD2A in A549 cells enhanced autophagy and inhibited H1N1 replication. By contrast, overexpression of circ-GATAD2A impaired autophagy and promoted H1N1 replication. Similarly, knockout of vacuolar protein sorting 34 (VPS34) blocked autophagy and increased H1N1 replication. However, the expression of circ-GATAD2A could not further enhance H1N1 replication in VPS34 knockout cells. Collectively, these data indicated that circ-GATAD2A promotes the replication of H1N1 by inhibiting autophagy.Keywords: autophagy, circ-GATAD2A, H1N1, replication
Procedia PDF Downloads 154767 Trace Network: A Probabilistic Relevant Pattern Recognition Approach to Attribution Trace Analysis
Authors: Jian Xu, Xiaochun Yun, Yongzheng Zhang, Yafei Sang, Zhenyu Cheng
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Network attack prevention is a critical research area of information security. Network attack would be oppressed if attribution techniques are capable to trace back to the attackers after the hacking event. Therefore attributing these attacks to a particular identification becomes one of the important tasks when analysts attempt to differentiate and profile the attacker behind a piece of attack trace. To assist analysts in expose attackers behind the scenes, this paper researches on the connections between attribution traces and proposes probabilistic relevance based attribution patterns. This method facilitates the evaluation of the plausibility relevance between different traceable identifications. Furthermore, through analyzing the connections among traces, it could confirm the existence probability of a certain organization as well as discover its affinitive partners by the means of drawing relevance matrix from attribution traces.Keywords: attribution trace, probabilistic relevance, network attack, attacker identification
Procedia PDF Downloads 366766 A Dirty Page Migration Method in Process of Memory Migration Based on Pre-copy Technology
Authors: Kang Zijian, Zhang Tingyu, Burra Venkata Durga Kumar
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This article investigates the challenges in memory migration during the live migration of virtual machines. We found three challenges probably existing in pre-copy technology. One of the main challenges is the challenge of downtime migration. Decrease the downtime could promise the normal work for a virtual machine. Although pre-copy technology is greatly decreasing the downtime, we still need to shut down the machine in order to finish the last round of data transfer. This paper provides an optimization scheme for the problems existing in pro-copy technology, mainly the optimization of the dirty page migration mechanism. The typical pre-copy technology copy n-1th’s dirty pages in nth turn. However, our idea is to create a double iteration method to solve this problem.Keywords: virtual machine, pre-copy technology, memory migration process, downtime, dirty pages migration method
Procedia PDF Downloads 150765 Multivariate Genome-Wide Association Studies for Identifying Additional Loci for Myopia
Authors: Qiao Fan, Xiaobo Guo, Junxian Zhu, Xiaohu Ding, Ching-Yu Cheng, Tien-Yin Wong, Mingguang He, Heping Zhang, Xueqin Wang
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A systematic, simultaneous analysis of multiple phenotypes in genome-wide association studies (GWASs) draws a great attention to integrate the signals from single phenotypes with increased power. However, lacking an interpretable and efficient multivariate GWAS analysis impede the application of such approach. In this study, we propose to decompose the multivariate model into a series of simple univariate models. This transformation illuminates what exactly the individual trait contributes to the significant signals from the multivariate analyses. By employing our approach in the analysis of three myopia-related endophenotypes from the Singapore Malay Eye Study (SIMES), we identify novel candidate loci which were successfully validated in an independent Guangzhou Twin Eye Study (GTES).Keywords: GWAS multivariate, multiple traits, myopia, association
Procedia PDF Downloads 223764 An Improved Circulating Tumor Cells Analysis Method for Identifying Tumorous Blood Cells
Authors: Salvador Garcia Bernal, Chi Zheng, Keqi Zhang, Lei Mao
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Circulating Tumor Cells (CTC) is used to detect tumoral cell metastases using blood samples of patients with cancer (lung, breast, etc.). Using an immunofluorescent method a three channel image (Red, Green, and Blue) are obtained. These set of images usually overpass the 11 x 30 M pixels in size. An aided tool is designed for imaging cell analysis to segmented and identify the tumorous cell based on the three markers signals. Our Method, it is cell-based (area and cell shape) considering each channel information and extracting and making decisions if it is a valid CTC. The system also gives information about number and size of tumor cells found in the sample. We present results in real-life samples achieving acceptable performance in identifying CTCs in short time.Keywords: Circulating Tumor Cells (CTC), cell analysis, immunofluorescent, medical image analysis
Procedia PDF Downloads 213763 Analysis of Nonlinear Bertrand Duopoly Game with Heterogeneous Players
Authors: Jixiang Zhang
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A dynamic of Bertrand duopoly game is analyzed, where players use different production methods and choose their prices with bounded rationality. The equilibriums of the corresponding discrete dynamical systems are investigated. The stability conditions of Nash equilibrium under a local adjustment process are studied. The stability conditions of Nash equilibrium under a local adjustment process are studied. The stability of Nash equilibrium, as some parameters of the model are varied, gives rise to complex dynamics such as cycles of higher order and chaos. On this basis, we discover that an increase of adjustment speed of bounded rational player can make Bertrand market sink into the chaotic state. Finally, the complex dynamics, bifurcations and chaos are displayed by numerical simulation.Keywords: Bertrand duopoly model, discrete dynamical system, heterogeneous expectations, nash equilibrium
Procedia PDF Downloads 407