Search results for: M. S. Mahesh
23 A Programmable FSK-Modulator in 350nm CMOS Technology
Authors: Nasir Mehmood, Saad Rahman, Vinodh Ravinath, Mahesh Balaji
Abstract:
This paper describes the design of a programmable FSK-modulator based on VCO and its implementation in 0.35m CMOS process. The circuit is used to transmit digital data at 100Kbps rate in the frequency range of 400-600MHz. The design and operation of the modulator is discussed briefly. Further the characteristics of PLL, frequency synthesizer, VCO and the whole design are elaborated. The variation among the proposed and tested specifications is presented. Finally, the layout of sub-modules, pin configurations, final chip and test results are presented.Keywords: FSK Modulator, CMOS, VCO, Phase Locked Loop, Frequency Synthesizer.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 172922 Vibration Damping of High-Chromium Ferromagnetic Steel
Authors: Satish BM, Girish BM , Mahesh K
Abstract:
The aim of the present work is to study the effect of annealing on the vibration damping capacity of high-chromium (16%) ferromagnetic steel. The alloys were prepared from raw materials of 99.9% purity melted in a high frequency induction furnace under high vacuum. The samples were heat-treated in vacuum at various temperatures (800 to 1200ºC) for 1 hour followed by slow cooling (120ºC/h). The inverted torsional pendulum method was used to evaluate the vibration damping capacity. The results indicated that the vibration damping capacity of the alloys is influenced by annealing and there exists a critical annealing temperature after 1000ºC. The damping capacity increases quickly below the critical temperature since the magnetic domains move more easily.
Keywords: Vibration, Damping, Ferromagnetic, Steel.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 216421 Modeling and Simulation of Photovoltaic based LED Lighting System
Authors: Ankit R Patel, Ankit A Patel, Mahesh A Patel, Dhaval R Vyas
Abstract:
Although lighting systems powered by Photovoltaic (PV) cells have existed for many years, they are not widely used, especially in lighting for buildings, due to their high initial cost and low conversion efficiency. One of the technical challenges facing PV powered lighting systems has been how to use dc power generated by the PV module to energize common light sources that are designed to operate efficiently under ac power. Usually, the efficiency of the dc light sources is very poor compared to ac light sources. Rapid developments in LED lighting systems have made this technology a potential candidate for PV powered lighting systems. This study analyzed the efficiency of each component of PV powered lighting systems to identify optimum system configurations for different applications.Keywords: Energy Efficiency, LED, Modeling of systems, Photovoltaic.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 320420 Non-Contact Digital Music Instrument Using Light Sensing Technology
Authors: Aishwarya Ravichandra, Kirtana Kirtivasan, Adithi Mahesh, Ashwini S.Savanth
Abstract:
A Non-Contact Digital Music System has been conceptualized and implemented to create a new era of digital music. This system replaces the strings of a traditional stringed instrument with laser beams to avoid bruising of the user’s hand. The system consists of seven laser modules, detector modules and distance sensors that form the basic hardware blocks of this instrument. Arduino ATmega2560 microcontroller is used as the primary interface between the hardware and the software. MIDI (Musical Instrument Digital Interface) is used as the protocol to establish communication between the instrument and the virtual synthesizer software.
Keywords: Arduino, Detector, Laser, MIDI, NOTE ON, NOTE OFF, PITCH BEND, Sharp IR distance sensor.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 157919 Comparative Study of Static and Dynamic Bending Forces during 3-Roller Cone Frustum Bending Process
Authors: Mahesh K. Chudasama, Harit K. Raval
Abstract:
3-roller conical bending process is widely used in the industries for manufacturing of conical sections and shells. It involves static as well dynamic bending stages. Analytical models for prediction of bending force during static as well as dynamic bending stage are available in the literature. In this paper bending forces required for static bending stage and dynamic bending stages have been compared using the analytical models. It is concluded that force required for dynamic bending is very less as compared to the bending force required during the static bending stage.Keywords: Analytical modeling, cone frustum, dynamic bending, static bending.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 263618 A Comparative Study of Force Prediction Models during Static Bending Stage for 3-Roller Cone Frustum Bending
Authors: Mahesh Chudasama, Harit Raval
Abstract:
Conical sections and shells of metal plates manufactured by 3-roller conical bending process are widely used in the industries. The process is completed by first bending the metal plates statically and then dynamic roller bending sequentially. It is required to have an analytical model to get maximum bending force, for optimum design of the machine, for static bending stage. Analytical models assuming various stress conditions are considered and these analytical models are compared considering various parameters and reported in this paper. It is concluded from the study that for higher bottom roller inclination, the shear stress affects greatly to the static bending force whereas for lower bottom roller inclination it can be neglected.
Keywords: Roller-bending, static-bending, stress-conditions, analytical-modeling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 104617 Oncogene Identification using Filter based Approaches between Various Cancer Types in Lung
Authors: Michael Netzer, Michael Seger, Mahesh Visvanathan, Bernhard Pfeifer, Gerald H. Lushington, Christian Baumgartner
Abstract:
Lung cancer accounts for the most cancer related deaths for men as well as for women. The identification of cancer associated genes and the related pathways are essential to provide an important possibility in the prevention of many types of cancer. In this work two filter approaches, namely the information gain and the biomarker identifier (BMI) are used for the identification of different types of small-cell and non-small-cell lung cancer. A new method to determine the BMI thresholds is proposed to prioritize genes (i.e., primary, secondary and tertiary) using a k-means clustering approach. Sets of key genes were identified that can be found in several pathways. It turned out that the modified BMI is well suited for microarray data and therefore BMI is proposed as a powerful tool for the search for new and so far undiscovered genes related to cancer.
Keywords: lung cancer, micro arrays, data mining, feature selection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 175416 Fusion of ETM+ Multispectral and Panchromatic Texture for Remote Sensing Classification
Authors: Mahesh Pal
Abstract:
This paper proposes to use ETM+ multispectral data and panchromatic band as well as texture features derived from the panchromatic band for land cover classification. Four texture features including one 'internal texture' and three GLCM based textures namely correlation, entropy, and inverse different moment were used in combination with ETM+ multispectral data. Two data sets involving combination of multispectral, panchromatic band and its texture were used and results were compared with those obtained by using multispectral data alone. A decision tree classifier with and without boosting were used to classify different datasets. Results from this study suggest that the dataset consisting of panchromatic band, four of its texture features and multispectral data was able to increase the classification accuracy by about 2%. In comparison, a boosted decision tree was able to increase the classification accuracy by about 3% with the same dataset.Keywords: Internal texture; GLCM; decision tree; boosting; classification accuracy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 173815 Assessing the Impact of Contour Strips of Perennial Grass with Bio-fuel Potentials on Aquatic Environment
Authors: Roy R. Gu, Mahesh Sahu
Abstract:
The use of contour strips of perennial vegetation with bio-fuel potential can improve surface water quality by reducing NO3-N and sediment outflow from cropland to surface water-bodies. It also has economic benefits of producing ethanol. In this study, The Soil and Water Assessment Tool (SWAT) model was applied to a watershed in Iowa, USA to examine the effectiveness of contour strips of switch grass in reducing the NO3-N outflows from crop fields to rivers or lakes. Numerical experiments were conducted to identify potential subbasins in the watershed that have high water quality impact, and to examine the effects of strip size on NO3-N reduction under various meteorological conditions, i.e. dry, average and wet years. Useful information was obtained for the evaluation of economic feasibility of growing switch grass for bio-fuel in contour strips. The results can assist in cost-benefit analysis and decisionmaking in best management practices for environmental protection.Keywords: ethanol, modeling, water quality, NO3-N, watershed.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 153314 Architecture of Speech-based Registration System
Authors: Mayank Kumar, D B Mahesh Kumar, Ashwin S Kumar, N K Srinath
Abstract:
In this era of technology, fueled by the pervasive usage of the internet, security is a prime concern. The number of new attacks by the so-called “bots", which are automated programs, is increasing at an alarming rate. They are most likely to attack online registration systems. Technology, called “CAPTCHA" (Completely Automated Public Turing test to tell Computers and Humans Apart) do exist, which can differentiate between automated programs and humans and prevent replay attacks. Traditionally CAPTCHA-s have been implemented with the challenge involved in recognizing textual images and reproducing the same. We propose an approach where the visual challenge has to be read out from which randomly selected keywords are used to verify the correctness of spoken text and in turn detect the presence of human. This is supplemented with a speaker recognition system which can identify the speaker also. Thus, this framework fulfills both the objectives – it can determine whether the user is a human or not and if it is a human, it can verify its identity.
Keywords: CAPTCHA, automatic speech recognition, keyword spotting.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 154813 Personal Authentication Using FDOST in Finger Knuckle-Print Biometrics
Authors: N. B. Mahesh Kumar, K. Premalatha
Abstract:
The inherent skin patterns created at the joints in the finger exterior are referred as finger knuckle-print. It is exploited to identify a person in a unique manner because the finger knuckle print is greatly affluent in textures. In biometric system, the region of interest is utilized for the feature extraction algorithm. In this paper, local and global features are extracted separately. Fast Discrete Orthonormal Stockwell Transform is exploited to extract the local features. Global feature is attained by escalating the size of Fast Discrete Orthonormal Stockwell Transform to infinity. Two features are fused to increase the recognition accuracy. A matching distance is calculated for both the features individually. Then two distances are merged mutually to acquire the final matching distance. The proposed scheme gives the better performance in terms of equal error rate and correct recognition rate.
Keywords: Hamming distance, Instantaneous phase, Region of Interest, Recognition accuracy.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 275912 Development of Analytical Model of Bending Force during 3-Roller Conical Bending Process and Its Experimental Verification
Authors: Mahesh Chudasama, Harit Raval
Abstract:
Conical sections and shells made from metal plates are widely used in various industrial applications. 3-roller conical bending process is preferably used to produce such conical sections and shells. Bending mechanics involved in the process is complex and little work is done in this area. In the present paper an analytical model is developed to predict bending force which will be acting during 3-roller conical bending process. To verify the developed model, conical bending experiments are performed. Analytical results and experimental results were compared. Force predicted by analytical model is in close proximity of the experimental results. The error in the prediction is ±10%. Hence the model gives quite satisfactory results. Present model is also compared with the previously published bending force prediction model and it is found that the present model gives better results. The developed model can be used to estimate the bending force during 3-roller bending process and can be useful to the designers for designing the 3-roller conical bending machine.
Keywords: Bending-force, Experimental-verification, Internal-moment, Roll-bending.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 402511 Thermal Analysis of Circular Pin-fin with Rectangular Slot at the Center by Forced Convection
Authors: Kavita H. Dhanawade, Hanamant S. Dhanawade, Ajay Kashikar, Shweta Matey, Mahesh Bhadane, Sunny Sarraf
Abstract:
Extended surfaces are commonly used in practice to enhance heat transfer. Most of the engineering problems require high performance heat transfer components with light weight, volumes, accommodating shapes, costs and reliability depending on industrial applications. This paper reports an experimental analysis to investigate heat transfer enhancement by forced convection using different sizes of pin-fin with rectangular slots at the center. The cross sectional area of the oblong duct was 200 mm x 80 mm. The info utilized in performance analysis was obtained experimentally for material, aluminum at 200 Watts heat input varying velocity 1 m/s to 5 m/s. Using the Taguchi experimental design method, optimum design parameters and their levels were analysed. Nusselt number and friction factor were considered as a performance characteristic parameter. An An L9 (33) orthogonal array was designated as an experimental proposal. Optimum results were found by experimenting. It is observed that pin-fins with different slots sizes have a better impact on Nusselt Number.Keywords: Heat transfer coefficient, Nusselt Number, pin-fin, forced convection.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 80610 Artificial Neural Network based Modeling of Evaporation Losses in Reservoirs
Authors: Surinder Deswal, Mahesh Pal
Abstract:
An Artificial Neural Network based modeling technique has been used to study the influence of different combinations of meteorological parameters on evaporation from a reservoir. The data set used is taken from an earlier reported study. Several input combination were tried so as to find out the importance of different input parameters in predicting the evaporation. The prediction accuracy of Artificial Neural Network has also been compared with the accuracy of linear regression for predicting evaporation. The comparison demonstrated superior performance of Artificial Neural Network over linear regression approach. The findings of the study also revealed the requirement of all input parameters considered together, instead of individual parameters taken one at a time as reported in earlier studies, in predicting the evaporation. The highest correlation coefficient (0.960) along with lowest root mean square error (0.865) was obtained with the input combination of air temperature, wind speed, sunshine hours and mean relative humidity. A graph between the actual and predicted values of evaporation suggests that most of the values lie within a scatter of ±15% with all input parameters. The findings of this study suggest the usefulness of ANN technique in predicting the evaporation losses from reservoirs.Keywords: Artificial neural network, evaporation losses, multiple linear regression, modeling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 19799 Process Parameter Optimization in Resistance Spot Welding of Dissimilar Thickness Materials
Authors: Pradeep M., N. S. Mahesh, Raja Hussain
Abstract:
Resistance spot welding (RSW) has been used widely to join sheet metals. It has been a challenge to get required weld quality in spot welding of dissimilar thickness materials. Weld parameters are not generally available in standards for thickness beyond 4mm. This paper presents the welding process design and parameter optimization of RSW used in joining of low carbon steel sheet of thickness 0.8 mm and metal strips of cross section 10 x 5mm for electrical motor applications. Taguchi quality design was adopted for weld current and time optimization using L9 orthogonal array. Optimum process parameters (current- 3.5kA and time- 10 cycles) were obtained from the Taguchi analysis and shear test results. Confirmation experiment result revealed that the weld quality was within acceptable interval. Further, numerical simulation of RSW process was carried out with selected weld parameters to quantify the temperature at faying surface and check for formation of appropriate nugget. The nugget geometry measured after peel test and predicted from numerical validation method were similar and in accordance with the standards.
Keywords: Resistance spot welding, dissimilar thickness, weld parameters, Taguchi method, numerical modeling.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 51898 Three-Dimensional, Non-Linear Finite Element Analysis of Bullet Penetration through Thin AISI 4340 Steel Target Plate
Authors: Abhishek Soni, A. Kumaraswamy, M. S. Mahesh
Abstract:
Bullet penetration in steel plate is investigated with the help of three-dimensional, non-linear, transient, dynamic, finite elements analysis using explicit time integration code LSDYNA. The effect of large strain, strain-rate and temperature at very high velocity regime was studied from number of simulations of semi-spherical nose shape bullet penetration through single layered circular plate with 2 mm thickness at impact velocities of 500, 1000, and 1500 m/s with the help of Johnson Cook material model. Mie-Gruneisen equation of state is used in conjunction with Johnson Cook material model to determine pressure-volume relationship at various points of interests. Two material models viz. Plastic-Kinematic and Johnson- Cook resulted in different deformation patterns in steel plate. It is observed from the simulation results that the velocity drop and loss of kinetic energy occurred very quickly up to perforation of plate, after that the change in velocity and changes in kinetic energy are negligibly small. The physics behind this kind of behaviour is presented in the paper.Keywords: AISI 4340 steel, ballistic impact simulation, bullet penetration, non-linear FEM.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 12647 Ensemble Learning with Decision Tree for Remote Sensing Classification
Authors: Mahesh Pal
Abstract:
In recent years, a number of works proposing the combination of multiple classifiers to produce a single classification have been reported in remote sensing literature. The resulting classifier, referred to as an ensemble classifier, is generally found to be more accurate than any of the individual classifiers making up the ensemble. As accuracy is the primary concern, much of the research in the field of land cover classification is focused on improving classification accuracy. This study compares the performance of four ensemble approaches (boosting, bagging, DECORATE and random subspace) with a univariate decision tree as base classifier. Two training datasets, one without ant noise and other with 20 percent noise was used to judge the performance of different ensemble approaches. Results with noise free data set suggest an improvement of about 4% in classification accuracy with all ensemble approaches in comparison to the results provided by univariate decision tree classifier. Highest classification accuracy of 87.43% was achieved by boosted decision tree. A comparison of results with noisy data set suggests that bagging, DECORATE and random subspace approaches works well with this data whereas the performance of boosted decision tree degrades and a classification accuracy of 79.7% is achieved which is even lower than that is achieved (i.e. 80.02%) by using unboosted decision tree classifier.Keywords: Ensemble learning, decision tree, remote sensingclassification.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 25866 Assessment of Heavy Metal Concentrations in Tunas Caught from Lakshweep Islands, India
Authors: Mahesh Kumar Farejiya, Anil Kumar Dikshit
Abstract:
The toxic metal contamination and their biomagnification in marine fishes is a serious public health concern specially, in the coastal areas and the small islands. In the present study, concentration of toxic heavy metals like zinc (Zn), cadmium (Cd), lead (Pb), nickel (Ni), cobalt (Co), chromium (Cr) and mercury (Hg) were determined in the tissues of tunas (T. albacores) caught from the area near to Lakshdweep Islands. The heavy metals are one of the indicators for the marine water pollution. Geochemical weathering, industrialization, agriculture run off, fishing, shipping and oil spills are the major pollutants. The presence of heavy toxic metals in the near coastal water fishes at both western coast and eastern coast of India has been well established. The present study was conducted assuming that the distant island will not have the metals presence in a way it is at the near main land coast. However, our study shows that there is a significant amount of the toxic metals present in the tissues of tuna samples. The gill, lever and flash samples were collected in waters around Lakshdweep Islands. They were analyzed using ICP–AES for the toxic metals after microwave digestion. The concentrations of the toxic metals were found in all fish samples and the general trend of presence was in decreasing order as Zn > Al > Cd > Pb > Cr > Ni > Hg. The amount of metals was found to higher in fish having more weight.
Keywords: Biomagnifications, marine environment, toxic heavy metals, Tuna fish.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 14255 Managing Iterations in Product Design and Development
Authors: K. Aravindhan, Trishit Bandyopadhyay, Mahesh Mehendale, Supriya Kumar De
Abstract:
The inherent iterative nature of product design and development poses significant challenge to reduce the product design and development time (PD). In order to shorten the time to market, organizations have adopted concurrent development where multiple specialized tasks and design activities are carried out in parallel. Iterative nature of work coupled with the overlap of activities can result in unpredictable time to completion and significant rework. Many of the products have missed the time to market window due to unanticipated or rather unplanned iteration and rework. The iterative and often overlapped processes introduce greater amounts of ambiguity in design and development, where the traditional methods and tools of project management provide less value. In this context, identifying critical metrics to understand the iteration probability is an open research area where significant contribution can be made given that iteration has been the key driver of cost and schedule risk in PD projects. Two important questions that the proposed study attempts to address are: Can we predict and identify the number of iterations in a product development flow? Can we provide managerial insights for a better control over iteration? The proposal introduces the concept of decision points and using this concept intends to develop metrics that can provide managerial insights into iteration predictability. By characterizing the product development flow as a network of decision points, the proposed research intends to delve further into iteration probability and attempts to provide more clarity.
Keywords: Decision Points, Iteration, Product Design, Rework.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 21924 Improved Estimation of Evolutionary Spectrum based on Short Time Fourier Transforms and Modified Magnitude Group Delay by Signal Decomposition
Authors: H K Lakshminarayana, J S Bhat, H M Mahesh
Abstract:
A new estimator for evolutionary spectrum (ES) based on short time Fourier transform (STFT) and modified group delay function (MGDF) by signal decomposition (SD) is proposed. The STFT due to its built-in averaging, suppresses the cross terms and the MGDF preserves the frequency resolution of the rectangular window with the reduction in the Gibbs ripple. The present work overcomes the magnitude distortion observed in multi-component non-stationary signals with STFT and MGDF estimation of ES using SD. The SD is achieved either through discrete cosine transform based harmonic wavelet transform (DCTHWT) or perfect reconstruction filter banks (PRFB). The MGDF also improves the signal to noise ratio by removing associated noise. The performance of the present method is illustrated for cross chirp and frequency shift keying (FSK) signals, which indicates that its performance is better than STFT-MGDF (STFT-GD) alone. Further its noise immunity is better than STFT. The SD based methods, however cannot bring out the frequency transition path from band to band clearly, as there will be gap in the contour plot at the transition. The PRFB based STFT-SD shows good performance than DCTHWT decomposition method for STFT-GD.Keywords: Evolutionary Spectrum, Modified Group Delay, Discrete Cosine Transform, Harmonic Wavelet Transform, Perfect Reconstruction Filter Banks, Short Time Fourier Transform.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 16113 Water and Soil Environment Pollution Reduction by Filter Strips
Authors: Roy R. Gu, Mahesh Sahu, Xianggui Zhao
Abstract:
Contour filter strips planted with perennial vegetation can be used to improve surface and ground water quality by reducing pollutant, such as NO3-N, and sediment outflow from cropland to a river or lake. Meanwhile, the filter strips of perennial grass with biofuel potentials also have economic benefits of producing ethanol. In this study, The Soil and Water Assessment Tool (SWAT) model was applied to the Walnut Creek Watershed to examine the effectiveness of contour strips in reducing NO3-N outflows from crop fields to the river or lake. Required input data include watershed topography, slope, soil type, land-use, management practices in the watershed and climate parameters (precipitation, maximum/minimum air temperature, solar radiation, wind speed and relative humidity). Numerical experiments were conducted to identify potential subbasins in the watershed that have high water quality impact, and to examine the effects of strip size and location on NO3-N reduction in the subbasins under various meteorological conditions (dry, average and wet). Variable sizes of contour strips (10%, 20%, 30% and 50%, respectively, of a subbasin area) planted with perennial switchgrass were selected for simulating the effects of strip size and location on stream water quality. Simulation results showed that a filter strip having 10%-50% of the subbasin area could lead to 55%- 90% NO3-N reduction in the subbasin during an average rainfall year. Strips occupying 10-20% of the subbasin area were found to be more efficient in reducing NO3-N when placed along the contour than that when placed along the river. The results of this study can assist in cost-benefit analysis and decision-making in best water resources management practices for environmental protection.Keywords: modeling, SWAT, water quality, NO3-N, watershed.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 17432 Action Potential of Lateral Geniculate Neurons at Low Threshold Currents: Simulation Study
Authors: Faris Tarlochan, Siva Mahesh Tangutooru
Abstract:
Lateral Geniculate Nucleus (LGN) is the relay center in the visual pathway as it receives most of the input information from retinal ganglion cells (RGC) and sends to visual cortex. Low threshold calcium currents (IT) at the membrane are the unique indicator to characterize this firing functionality of the LGN neurons gained by the RGC input. According to the LGN functional requirements such as functional mapping of RGC to LGN, the morphologies of the LGN neurons were developed. During the neurological disorders like glaucoma, the mapping between RGC and LGN is disconnected and hence stimulating LGN electrically using deep brain electrodes can restore the functionalities of LGN. A computational model was developed for simulating the LGN neurons with three predominant morphologies each representing different functional mapping of RGC to LGN. The firings of action potentials at LGN neuron due to IT were characterized by varying the stimulation parameters, morphological parameters and orientation. A wide range of stimulation parameters (stimulus amplitude, duration and frequency) represents the various strengths of the electrical stimulation with different morphological parameters (soma size, dendrites size and structure). The orientation (0-1800) of LGN neuron with respect to the stimulating electrode represents the angle at which the extracellular deep brain stimulation towards LGN neuron is performed. A reduced dendrite structure was used in the model using Bush–Sejnowski algorithm to decrease the computational time while conserving its input resistance and total surface area. The major finding is that an input potential of 0.4 V is required to produce the action potential in the LGN neuron which is placed at 100 μm distance from the electrode. From this study, it can be concluded that the neuroprostheses under design would need to consider the capability of inducing at least 0.4V to produce action potentials in LGN.Keywords: Lateral geniculate nucleus, visual cortex, finite element, glaucoma, neuroprostheses.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 20251 Comparison of Multivariate Adaptive Regression Splines and Random Forest Regression in Predicting Forced Expiratory Volume in One Second
Authors: P. V. Pramila, V. Mahesh
Abstract:
Pulmonary Function Tests are important non-invasive diagnostic tests to assess respiratory impairments and provides quantifiable measures of lung function. Spirometry is the most frequently used measure of lung function and plays an essential role in the diagnosis and management of pulmonary diseases. However, the test requires considerable patient effort and cooperation, markedly related to the age of patients resulting in incomplete data sets. This paper presents, a nonlinear model built using Multivariate adaptive regression splines and Random forest regression model to predict the missing spirometric features. Random forest based feature selection is used to enhance both the generalization capability and the model interpretability. In the present study, flow-volume data are recorded for N= 198 subjects. The ranked order of feature importance index calculated by the random forests model shows that the spirometric features FVC, FEF25, PEF, FEF25-75, FEF50 and the demographic parameter height are the important descriptors. A comparison of performance assessment of both models prove that, the prediction ability of MARS with the `top two ranked features namely the FVC and FEF25 is higher, yielding a model fit of R2= 0.96 and R2= 0.99 for normal and abnormal subjects. The Root Mean Square Error analysis of the RF model and the MARS model also shows that the latter is capable of predicting the missing values of FEV1 with a notably lower error value of 0.0191 (normal subjects) and 0.0106 (abnormal subjects) with the aforementioned input features. It is concluded that combining feature selection with a prediction model provides a minimum subset of predominant features to train the model, as well as yielding better prediction performance. This analysis can assist clinicians with a intelligence support system in the medical diagnosis and improvement of clinical care.
Keywords: FEV1, Multivariate Adaptive Regression Splines Pulmonary Function Test, Random Forest.
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3738