Search results for: Pharmaceutical Sales Analysis
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 8814

Search results for: Pharmaceutical Sales Analysis

8244 Performance Analysis of the Time-Based and Periodogram-Based Energy Detector for Spectrum Sensing

Authors: Sadaf Nawaz, Adnan Ahmed Khan, Asad Mahmood, Chaudhary Farrukh Javed

Abstract:

Classically, an energy detector is implemented in time domain (TD). However, frequency domain (FD) based energy detector has demonstrated an improved performance. This paper presents a comparison between the two approaches as to analyze their pros and cons. A detailed performance analysis of the classical TD energy-detector and the periodogram based detector is performed. Exact and approximate mathematical expressions for probability of false alarm (Pf) and probability of detection (Pd) are derived for both approaches. The derived expressions naturally lead to an analytical as well as intuitive reasoning for the improved performance of (Pf) and (Pd) in different scenarios. Our analysis suggests the dependence improvement on buffer sizes. Pf is improved in FD, whereas Pd is enhanced in TD based energy detectors. Finally, Monte Carlo simulations results demonstrate the analysis reached by the derived expressions.

Keywords: Cognitive radio, energy detector, periodogram, spectrum sensing.

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8243 Performance of Histogram-Based Skin Colour Segmentation for Arms Detection in Human Motion Analysis Application

Authors: Rosalyn R. Porle, Ali Chekima, Farrah Wong, G. Sainarayanan

Abstract:

Arms detection is one of the fundamental problems in human motion analysis application. The arms are considered as the most challenging body part to be detected since its pose and speed varies in image sequences. Moreover, the arms are usually occluded with other body parts such as the head and torso. In this paper, histogram-based skin colour segmentation is proposed to detect the arms in image sequences. Six different colour spaces namely RGB, rgb, HSI, TSL, SCT and CIELAB are evaluated to determine the best colour space for this segmentation procedure. The evaluation is divided into three categories, which are single colour component, colour without luminance and colour with luminance. The performance is measured using True Positive (TP) and True Negative (TN) on 250 images with manual ground truth. The best colour is selected based on the highest TN value followed by the highest TP value.

Keywords: image colour analysis, image motion analysis, skin, wavelet transform.

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8242 Application of Mutual Information based Least dependent Component Analysis (MILCA) for Removal of Ocular Artifacts from Electroencephalogram

Authors: V Krishnaveni, S Jayaraman, K Ramadoss

Abstract:

The electrical potentials generated during eye movements and blinks are one of the main sources of artifacts in Electroencephalogram (EEG) recording and can propagate much across the scalp, masking and distorting brain signals. In recent times, signal separation algorithms are used widely for removing artifacts from the observed EEG data. In this paper, a recently introduced signal separation algorithm Mutual Information based Least dependent Component Analysis (MILCA) is employed to separate ocular artifacts from EEG. The aim of MILCA is to minimize the Mutual Information (MI) between the independent components (estimated sources) under a pure rotation. Performance of this algorithm is compared with eleven popular algorithms (Infomax, Extended Infomax, Fast ICA, SOBI, TDSEP, JADE, OGWE, MS-ICA, SHIBBS, Kernel-ICA, and RADICAL) for the actual independence and uniqueness of the estimated source components obtained for different sets of EEG data with ocular artifacts by using a reliable MI Estimator. Results show that MILCA is best in separating the ocular artifacts and EEG and is recommended for further analysis.

Keywords: Electroencephalogram, Ocular Artifacts (OA), Independent Component Analysis (ICA), Mutual Information (MI), Mutual Information based Least dependent Component Analysis(MILCA)

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8241 Analysis of Cooperative Learning Behavior Based on the Data of Students' Movement

Authors: Wang Lin, Li Zhiqiang

Abstract:

The purpose of this paper is to analyze the cooperative learning behavior pattern based on the data of students' movement. The study firstly reviewed the cooperative learning theory and its research status, and briefly introduced the k-means clustering algorithm. Then, it used clustering algorithm and mathematical statistics theory to analyze the activity rhythm of individual student and groups in different functional areas, according to the movement data provided by 10 first-year graduate students. It also focused on the analysis of students' behavior in the learning area and explored the law of cooperative learning behavior. The research result showed that the cooperative learning behavior analysis method based on movement data proposed in this paper is feasible. From the results of data analysis, the characteristics of behavior of students and their cooperative learning behavior patterns could be found.

Keywords: Behavior pattern, cooperative learning, data analyze, K-means clustering algorithm.

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8240 University Ranking Systems – From League Table to Homogeneous Groups of Universities

Authors: M. Jarocka

Abstract:

The paper contains a review of the literature in terms of the critical analysis of methodologies of university ranking systems. Furthermore, the initiatives supported by the European Commission (U-Map, U-Multirank) and CHE Ranking are described. Special attention is paid to the tendencies in the development of ranking systems. According to the author, the ranking organizations should abandon the classic form of ranking, namely a hierarchical ordering of universities from “the best" to “the worse". In the empirical part of this paper, using one of the method of cluster analysis called k-means clustering, the author presents university classifications of the top universities from the Shanghai Jiao Tong University-s (SJTU) Academic Ranking of World Universities (ARWU).

Keywords: Classification, cluster analysis, ranking, university.

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8239 Post Pandemic Mobility Analysis through Indexing and Sharding in MongoDB: Performance Optimization and Insights

Authors: Karan Vishavjit, Aakash Lakra, Shafaq Khan

Abstract:

The COVID-19 pandemic has pushed healthcare professionals to use big data analytics as a vital tool for tracking and evaluating the effects of contagious viruses. To effectively analyse huge datasets, efficient NoSQL databases are needed. The analysis of post-COVID-19 health and well-being outcomes and the evaluation of the effectiveness of government efforts during the pandemic is made possible by this research’s integration of several datasets, which cuts down on query processing time and creates predictive visual artifacts. We recommend applying sharding and indexing technologies to improve query effectiveness and scalability as the dataset expands. Effective data retrieval and analysis are made possible by spreading the datasets into a sharded database and doing indexing on individual shards. Analysis of connections between governmental activities, poverty levels, and post-pandemic wellbeing is the key goal. We want to evaluate the effectiveness of governmental initiatives to improve health and lower poverty levels. We will do this by utilising advanced data analysis and visualisations. The findings provide relevant data that support the advancement of UN sustainable objectives, future pandemic preparation, and evidence-based decision-making. This study shows how Big Data and NoSQL databases may be used to address problems with global health.

Keywords: COVID-19, big data, data analysis, indexing, NoSQL, sharding, scalability, poverty.

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8238 Sentiment Analysis of Fake Health News Using Naive Bayes Classification Models

Authors: Danielle Shackley, Yetunde Folajimi

Abstract:

As more people turn to the internet seeking health related information, there is more risk of finding false, inaccurate, or dangerous information. Sentiment analysis is a natural language processing technique that assigns polarity scores of text, ranging from positive, neutral and negative. In this research, we evaluate the weight of a sentiment analysis feature added to fake health news classification models. The dataset consists of existing reliably labeled health article headlines that were supplemented with health information collected about COVID-19 from social media sources. We started with data preprocessing, tested out various vectorization methods such as Count and TFIDF vectorization. We implemented 3 Naive Bayes classifier models, including Bernoulli, Multinomial and Complement. To test the weight of the sentiment analysis feature on the dataset, we created benchmark Naive Bayes classification models without sentiment analysis, and those same models were reproduced and the feature was added. We evaluated using the precision and accuracy scores. The Bernoulli initial model performed with 90% precision and 75.2% accuracy, while the model supplemented with sentiment labels performed with 90.4% precision and stayed constant at 75.2% accuracy. Our results show that the addition of sentiment analysis did not improve model precision by a wide margin; while there was no evidence of improvement in accuracy, we had a 1.9% improvement margin of the precision score with the Complement model. Future expansion of this work could include replicating the experiment process, and substituting the Naive Bayes for a deep learning neural network model.

Keywords: Sentiment analysis, Naive Bayes model, natural language processing, topic analysis, fake health news classification model.

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8237 Small Signal Stability Assessment of MEPE Test System in Free and Open Source Software

Authors: Kyaw Myo Lin

Abstract:

This paper presents small signal stability study carried over the 140-Bus, 31-Machine, 5-Area MEPE system and validated on free and open source software: PSAT. Well-established linearalgebra analysis, eigenvalue analysis, is employed to determine the small signal dynamic behavior of test system. The aspects of local and interarea oscillations which may affect the operation and behavior of power system are analyzed. Eigenvalue analysis is carried out to investigate the small signal behavior of test system and the participation factors have been determined to identify the participation of the states in the variation of different mode shapes. Also, the variations in oscillatory modes are presented to observe the damping performance of the test system.

Keywords: Eigenvalue analysis, Mode shapes, MEPE test system, Participation factors, Power System oscillations.

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8236 Round Addition Differential Fault Analysis on Lightweight Block Ciphers with On-the-Fly Key Scheduling

Authors: Hideki Yoshikawa, Masahiro Kaminaga, Arimitsu Shikoda, Toshinori Suzuki

Abstract:

Round addition differential fault analysis using operation skipping for lightweight block ciphers with on-the-fly key scheduling is presented. For 64-bit KLEIN, it is shown that only a pair of correct and faulty ciphertexts can be used to derive the secret master key. For PRESENT, one correct ciphertext and two faulty ciphertexts are required to reconstruct the secret key. Furthermore, secret key extraction is demonstrated for the LBlock Feistel-type lightweight block cipher.

Keywords: Differential Fault Analysis (DFA), round addition, block cipher, on-the-fly key schedule.

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8235 Spatial Variability of Brahmaputra River Flow Characteristics

Authors: Hemant Kumar

Abstract:

Brahmaputra River is known according to the Hindu mythology the son of the Lord Brahma. According to this name, the river Brahmaputra creates mass destruction during the monsoon season in Assam, India. It is a state situated in North-East part of India. This is one of the essential states out of the seven countries of eastern India, where almost all entire Brahmaputra flow carried out. The other states carry their tributaries. In the present case study, the spatial analysis performed in this specific case the number of MODIS data are acquired. In the method of detecting the change, the spray content was found during heavy rainfall and in the flooded monsoon season. By this method, particularly the analysis over the Brahmaputra outflow determines the flooded season. The charged particle-associated in aerosol content genuinely verifies the heavy water content below the ground surface, which is validated by trend analysis through rainfall spectrum data. This is confirmed by in-situ sampled view data from a different position of Brahmaputra River. Further, a Hyperion Hyperspectral 30 m resolution data were used to scan the sediment deposits, which is also confirmed by in-situ sampled view data from a different position.

Keywords: Spatial analysis, change detection, aerosol, trend analysis.

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8234 Face Recognition with PCA and KPCA using Elman Neural Network and SVM

Authors: Hossein Esbati, Jalil Shirazi

Abstract:

In this paper, in order to categorize ORL database face pictures, principle Component Analysis (PCA) and Kernel Principal Component Analysis (KPCA) methods by using Elman neural network and Support Vector Machine (SVM) categorization methods are used. Elman network as a recurrent neural network is proposed for modeling storage systems and also it is used for reviewing the effect of using PCA numbers on system categorization precision rate and database pictures categorization time. Categorization stages are conducted with various components numbers and the obtained results of both Elman neural network categorization and support vector machine are compared. In optimum manner 97.41% recognition accuracy is obtained.

Keywords: Face recognition, Principal Component Analysis, Kernel Principal Component Analysis, Neural network, Support Vector Machine.

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8233 Determinants of Consumer Choice for Online Travel Shopping Sites: A Confirmatory Analysis

Authors: Yu-Min Wang

Abstract:

This study attempts to validate the consumer-oriented criteria list, developed by Wang et al. (2010), for selecting online travel shopping sites. Based on a sample of 985 respondents, confirmatory factor analysis was employed to test the factor structure and assess the reliability and validity of the list. The results support the list developed by Wang et al. (2010) and claim the list can be further used to analyze, explain, and understand consumer behaviors about online travel shopping.

Keywords: Online travel agency, online travel shopping sites, confirmatory analysis.

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8232 Kinematic Analysis of Roll Motion for a Strut/SLA Suspension System

Authors: Yung Chang Chen, Po Yi Tsai, I An Lai

Abstract:

The roll center is one of the key parameters for designing a suspension. Several driving characteristics are affected significantly by the migration of the roll center during the suspension-s motion. The strut/SLA (strut/short-long-arm) suspension, which is widely used in production cars, combines the space-saving characteristics of a MacPherson strut suspension with some of the preferred handling characteristics of an SLA suspension. In this study, a front strut/SLA suspension is modeled by ADAMS/Car software. Kinematic roll analysis is then employed to investigate how the rolling characteristics change under the wheel travel and steering input. The related parameters, including the roll center height, roll camber gain, toe change, scrub radius and wheel track width change, are analyzed and discussed. It is found that the strut/SLA suspension clearly has a higher roll center than strut and SLA suspensions do. The variations in the roll center height under roll analysis are very different as the wheel travel displacement and steering angle are added. The results of the roll camber gain, scrub radius and wheel track width change are considered satisfactory. However, the toe change is too large and needs fine-tuning through a sensitivity analysis.

Keywords: roll analysis, roll center height, steering, strut/SLA suspension, wheel travel

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8231 When Construction Material Traders Goes Electronic: Analysis of SMEs in Malaysian Construction Industry

Authors: Dzul Fahmi Nordin, Rosmini Omar

Abstract:

This paper analyzed the perception of e-commerce application services by construction material traders in Malaysia. Five attributes were tested: usability, reputation, trust, privacy and familiarity. Study methodology consists of survey questionnaire and statistical analysis that includes reliability analysis, factor analysis, ANOVA and regression analysis. The respondents were construction material traders, including hardware stores in Klang Valley, Kuala Lumpur. Findings support that usability and familiarity with e-commerce services in Malaysia have insignificant influence on the acceptance of e-commerce application. However, reputation, trust and privacy attributes have significant influence on the choice of e-commerce acceptance by construction material traders. E-commerce applications studied included customer database, e-selling, emarketing, e-payment, e-buying and online advertising. Assumptions are made that traders have basic knowledge and exposure to ICT services. i.e. internet service and computers. Study concludes that reputation, privacy and trust are the three website attributes that influence the acceptance of e-commerce by construction material traders.

Keywords: Electronic Commerce (e-Commerce), Information and Communications Technology (ICT), Small Medium Enterprise (SME)

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8230 Automatic Fluid-Structure Interaction Modeling and Analysis of Butterfly Valve Using Python Script

Authors: N. Guru Prasath, Sangjin Ma, Chang-Wan Kim

Abstract:

A butterfly valve is a quarter turn valve which is used to control the flow of a fluid through a section of pipe. Generally, butterfly valve is used in wide range of applications such as water distribution, sewage, oil and gas plants. In particular, butterfly valve with larger diameter finds its immense applications in hydro power plants to control the fluid flow. In-lieu with the constraints in cost and size to run laboratory setup, analysis of large diameter values will be mostly studied by computational method which is the best and inexpensive solution. For fluid and structural analysis, CFD and FEM software is used to perform large scale valve analyses, respectively. In order to perform above analysis in butterfly valve, the CAD model has to recreate and perform mesh in conventional software’s for various dimensions of valve. Therefore, its limitation is time consuming process. In-order to overcome that issue, python code was created to outcome complete pre-processing setup automatically in Salome software. Applying dimensions of the model clearly in the python code makes the running time comparatively lower and easier way to perform analysis of the valve. Hence, in this paper, an attempt was made to study the fluid-structure interaction (FSI) of butterfly valves by varying the valve angles and dimensions using python code in pre-processing software, and results are produced.

Keywords: Butterfly valve, fluid-structure interaction, automatic CFD analysis, flow coefficient.

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8229 Intelligent Aid-Analysis Based on the Use of Digital Twin: Application to Electronic Warfare System

Authors: L. Chaussy, M. Nouvel

Abstract:

Workload of the system engineers during Integration Validation Verification process of Electronic Warfare Systems (EWS) is growing with complexity of the systems and with the diversity of tested cases (diversity of operational scenario in front of EWS). Even if the use of Digital Twin makes easier conception and development phases in term of planning and test equipment availability, time to analyze tests results is still too long and too complex. The idea to reduce the system engineer’s workload and improve test coverage is to introduce some intelligent and aid-analysis algorithms to improve this step.

Keywords: Analysis tools, automatic testing, digital twin, electronic warfare system.

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8228 Evaluation of Mixed-Mode Stress Intensity Factor by Digital Image Correlation and Intelligent Hybrid Method

Authors: K. Machida, H. Yamada

Abstract:

Displacement measurement was conducted on compact normal and shear specimens made of acrylic homogeneous material subjected to mixed-mode loading by digital image correlation. The intelligent hybrid method proposed by Nishioka et al. was applied to the stress-strain analysis near the crack tip. The accuracy of stress-intensity factor at the free surface was discussed from the viewpoint of both the experiment and 3-D finite element analysis. The surface images before and after deformation were taken by a CMOS camera, and we developed the system which enabled the real time stress analysis based on digital image correlation and inverse problem analysis. The great portion of processing time of this system was spent on displacement analysis. Then, we tried improvement in speed of this portion. In the case of cracked body, it is also possible to evaluate fracture mechanics parameters such as the J integral, the strain energy release rate, and the stress-intensity factor of mixed-mode. The 9-points elliptic paraboloid approximation could not analyze the displacement of submicron order with high accuracy. The analysis accuracy of displacement was improved considerably by introducing the Newton-Raphson method in consideration of deformation of a subset. The stress-intensity factor was evaluated with high accuracy of less than 1% of the error.

Keywords: Digital image correlation, mixed mode, Newton-Raphson method, stress intensity factor.

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8227 Analysis of Blind Decision Feedback Equalizer Convergence: Interest of a Soft Decision

Authors: S. Cherif, S. Marcos, M. Jaidane

Abstract:

In this paper the behavior of the decision feedback equalizers (DFEs) adapted by the decision-directed or the constant modulus blind algorithms is presented. An analysis of the error surface of the corresponding criterion cost functions is first developed. With the intention of avoiding the ill-convergence of the algorithm, the paper proposes to modify the shape of the cost function error surface by using a soft decision instead of the hard one. This was shown to reduce the influence of false decisions and to smooth the undesirable minima. Modified algorithms using the soft decision during a pseudo-training phase with an automatic switch to the properly tracking phase are then derived. Computer simulations show that these modified algorithms present better ability to avoid local minima than conventional ones.

Keywords: Blind DFEs, decision-directed algorithm, constant modulus algorithm, cost function analysis, convergence analysis, soft decision.

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8226 Using Social Network Analysis for Cyber Threat Intelligence

Authors: Vasileios Anastopoulos

Abstract:

Cyber threat intelligence assists organisations in understanding the threats they face and helps them make educated decisions on preparing their defences. Sharing of threat intelligence and threat information is increasingly leveraged by organisations and enterprises, and various software solutions are already available, with the open-source malware information sharing platform (MISP) being a popular one. In this work, a methodology for the production of cyber threat intelligence using the threat information stored in MISP is proposed. The methodology leverages the discipline of social network analysis and the diamond model, a model used for intrusion analysis, to produce cyber threat intelligence. The workings of the proposed methodology are demonstrated with a case study on a production MISP instance of a real organisation. The paper concludes with a discussion on the proposed methodology and possible directions for further research.

Keywords: Cyber threat intelligence, diamond model, malware information sharing platform, social network analysis.

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8225 Optimization of Loudspeaker Part Design Parameters by Air Viscosity Damping Effect

Authors: Yue Hu, Xilu Zhao, Takao Yamaguchi, Manabu Sasajima, Yoshio Koike, Akira Hara

Abstract:

This study optimized the design parameters of a cone loudspeaker as an example of high flexibility of the product design. We developed an acoustic analysis software program that considers the impact of damping caused by air viscosity. In sound reproduction, it is difficult to optimize each parameter of the loudspeaker design. To overcome the limitation of the design problem in practice, this study presents an acoustic analysis algorithm to optimize the design parameters of the loudspeaker. The material character of cone paper and the loudspeaker edge were the design parameters, and the vibration displacement of the cone paper was the objective function. The results of the analysis showed that the design had high accuracy as compared to the predicted value. These results suggested that although the parameter design is difficult, with experience and intuition, the design can be performed easily using the optimized design found with the acoustic analysis software.

Keywords: Air viscosity, design parameters, loudspeaker, optimization.

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8224 Coherence Analysis between Respiration and PPG Signal by Bivariate AR Model

Authors: Yue-Der Lin, Wei-Ting Liu, Ching-Che Tsai, Wen-Hsiu Chen

Abstract:

PPG is a potential tool in clinical applications. Among such, the relationship between respiration and PPG signal has attracted attention in past decades. In this research, a bivariate AR spectral estimation method was utilized for the coherence analysis between these two signals. Ten healthy subjects participated in this research with signals measured at different respiratory rates. The results demonstrate that high coherence exists between respiration and PPG signal, whereas the coherence disappears in breath-holding experiments. These results imply that PPG signal reveals the respiratory information. The utilized method may provide an attractive alternative approach for the related researches.

Keywords: Coherence analysis, photoplethysmography (PPG), bivariate AR spectral estimation.

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8223 Advanced Image Analysis Tools Development for the Early Stage Bronchial Cancer Detection

Authors: P. Bountris, E. Farantatos, N. Apostolou

Abstract:

Autofluorescence (AF) bronchoscopy is an established method to detect dysplasia and carcinoma in situ (CIS). For this reason the “Sotiria" Hospital uses the Karl Storz D-light system. However, in early tumor stages the visualization is not that obvious. With the help of a PC, we analyzed the color images we captured by developing certain tools in Matlab®. We used statistical methods based on texture analysis, signal processing methods based on Gabor models and conversion algorithms between devicedependent color spaces. Our belief is that we reduced the error made by the naked eye. The tools we implemented improve the quality of patients' life.

Keywords: Bronchoscopy, digital image processing, lung cancer, texture analysis.

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8222 Competitor Analysis to Quantify the Benefits and for Different Use of Transport Infrastructure

Authors: Dimitrios J. Dimitriou, Maria F. Sartzetaki

Abstract:

Different transportation modes have key operational advantages and disadvantages, providing a variety of different transport options to users and passengers. This paper reviews key variables for the competition between air transport and other transport modes. The aim of this paper is to review the competition between air transport and other transport modes, providing results in terms of perceived cost for the users, for destinations high competitiveness for all transport modes. The competitor analysis variables include the cost and time outputs for each transport option, highlighting the level of competitiveness on high demanded Origin-Destination corridors. The case study presents the output of a such analysis for the OD corridor in Greece that connects the Capital city (Athens) with the second largest city (Thessaloniki) and the different transport modes have been considered (air, train, road). Conventional wisdom is to present an easy to handle tool for planners, managers and decision makers towards pricing policy effectiveness and demand attractiveness, appropriate to use for other similar cases.

Keywords: Competitor analysis, generalized cost, transport economics, quantitative modelling.

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8221 Probabilistic Robustness Assessment of Structures under Sudden Column-Loss Scenario

Authors: Ali Y Al-Attraqchi, P. Rajeev, M. Javad Hashemi, Riadh Al-Mahaidi

Abstract:

This paper presents a probabilistic incremental dynamic analysis (IDA) of a full reinforced concrete building subjected to column loss scenario for the assessment of progressive collapse. The IDA is chosen to explicitly account for uncertainties in loads and system capacity. Fragility curves are developed to predict the probability of progressive collapse given the loss of one or more columns. At a broader scale, it will also provide critical information needed to support the development of a new generation of design codes that attempt to explicitly quantify structural robustness.

Keywords: Incremental dynamic analysis, progressive collapse, structural engineering, pushdown analysis.

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8220 The Impact of Bus Rapid Transit on Land Development: A Case Study of Beijing, China

Authors: Taotao Deng, John D. Nelson

Abstract:

Bus Rapid Transit (BRT) has emerged as a cost-effective transport system for urban mobility. However its ability to stimulate land development remains largely unexplored. The study makes use of qualitative (interview method) and quantitative analysis (questionnaire survey and longitudinal analysis of property data) to investigate land development impact resulting from BRT in Beijing, China. The empirical analysis suggests that BRT has a positive impact on the residential and commercial property attractiveness along the busway corridor. The statistical analysis suggests that accessibility advantage conferred by BRT is capitalized into higher property price. The average price of apartments adjacent to a BRT station has gained a relatively faster increase than those not served by the BRT system. The capitalization effect mostly occurs after the full operation of BRT, and is more evident over time and particularly observed in areas which previously lack alternative mobility opportunity.

Keywords: accessibility, Bus Rapid Transit (BRT), Beijing, property value uplift

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8219 Application of Artificial Neural Network in Assessing Fill Slope Stability

Authors: An-Jui. Li, Kelvin Lim, Chien-Kuo Chiu, Benson Hsiung

Abstract:

This paper details the utilization of artificial intelligence (AI) in the field of slope stability whereby quick and convenient solutions can be obtained using the developed tool. The AI tool used in this study is the artificial neural network (ANN), while the slope stability analysis methods are the finite element limit analysis methods. The developed tool allows for the prompt prediction of the safety factors of fill slopes and their corresponding probability of failure (depending on the degree of variation of the soil parameters), which can give the practicing engineer a reasonable basis in their decision making. In fact, the successful use of the Extreme Learning Machine (ELM) algorithm shows that slope stability analysis is no longer confined to the conventional methods of modeling, which at times may be tedious and repetitive during the preliminary design stage where the focus is more on cost saving options rather than detailed design. Therefore, similar ANN-based tools can be further developed to assist engineers in this aspect.

Keywords: Landslide, limit analysis, ANN, soil properties.

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8218 Patient Support Program in Pharmacovigilance: Foster Patient Confidence and Compliance

Authors: Atul Khurana, Rajul Rastogi, Hans-Joachim Gamperl

Abstract:

The pharmaceutical companies are getting more inclined towards patient support programs (PSPs) which assist patients and/or healthcare professionals (HCPs) in more desirable disease management and cost-effective treatment. The utmost objective of these programs is patient care. The PSPs may include financial assistance to patients, medicine compliance programs, access to HCPs via phone or online chat centers, etc. The PSP has a crucial role in terms of customer acquisition and retention strategies. During the conduct of these programs, Marketing Authorisation Holder (MAH) may receive information related to concerned medicinal products, which is usually reported by patients or involved HCPs. This information may include suspected adverse reaction(s) during/after administration of medicinal products. Hence, the MAH should design PSP to comply with regulatory reporting requirements and avoid non-compliance during PV inspection. The emergence of wireless health devices is lowering the burden on patients to manually incorporate safety data, and building a significant option for patients to observe major swings in reference to drug safety. Therefore, to enhance the adoption of these programs, MAH not only needs to aware patients about advantages of the program, but also recognizes the importance of time of patients and commitments made in a constructive manner. It is indispensable that strengthening the public health is considered as the topmost priority in such programs, and the MAH is compliant to Pharmacovigilance (PV) requirements along with regulatory obligations.

Keywords: Drug safety, good pharmacovigilance practice, patient support program, pharmacovigilance.

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8217 Comprehensive Analysis of Data Mining Tools

Authors: S. Sarumathi, N. Shanthi

Abstract:

Due to the fast and flawless technological innovation there is a tremendous amount of data dumping all over the world in every domain such as Pattern Recognition, Machine Learning, Spatial Data Mining, Image Analysis, Fraudulent Analysis, World Wide Web etc., This issue turns to be more essential for developing several tools for data mining functionalities. The major aim of this paper is to analyze various tools which are used to build a resourceful analytical or descriptive model for handling large amount of information more efficiently and user friendly. In this survey the diverse tools are illustrated with their extensive technical paradigm, outstanding graphical interface and inbuilt multipath algorithms in which it is very useful for handling significant amount of data more indeed.

Keywords: Classification, Clustering, Data Mining, Machine learning, Visualization.

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8216 Estimation of Attenuation and Phase Delay in Driving Voltage Waveform of an Ultra-High-Speed Image Sensor by Dimensional Analysis

Authors: V. T. S. Dao, T. G. Etoh, C. Vo Le, H. D. Nguyen, K. Takehara, T. Akino, K. Nishi

Abstract:

We present an explicit expression to estimate driving voltage attenuation through RC networks representation of an ultrahigh- speed image sensor. Elmore delay metric for a fundamental RC chain is employed as the first-order approximation. By application of dimensional analysis to SPICE simulation data, we found a simple expression that significantly improves the accuracy of the approximation. Estimation error of the resultant expression for uniform RC networks is less than 2%. Similarly, another simple closed-form model to estimate 50 % delay through fundamental RC networks is also derived with sufficient accuracy. The framework of this analysis can be extended to address delay or attenuation issues of other VLSI structures.

Keywords: Dimensional Analysis, Elmore model, RC network, Signal Attenuation, Ultra-High-Speed Image Sensor.

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8215 Multidimensional Visualization Tools for Analysis of Expression Data

Authors: Urska Cvek, Marjan Trutschl, Randolph Stone II, Zanobia Syed, John L. Clifford, Anita L. Sabichi

Abstract:

Expression data analysis is based mostly on the statistical approaches that are indispensable for the study of biological systems. Large amounts of multidimensional data resulting from the high-throughput technologies are not completely served by biostatistical techniques and are usually complemented with visual, knowledge discovery and other computational tools. In many cases, in biological systems we only speculate on the processes that are causing the changes, and it is the visual explorative analysis of data during which a hypothesis is formed. We would like to show the usability of multidimensional visualization tools and promote their use in life sciences. We survey and show some of the multidimensional visualization tools in the process of data exploration, such as parallel coordinates and radviz and we extend them by combining them with the self-organizing map algorithm. We use a time course data set of transitional cell carcinoma of the bladder in our examples. Analysis of data with these tools has the potential to uncover additional relationships and non-trivial structures.

Keywords: microarrays, visualization, parallel coordinates, radviz, self-organizing maps.

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