Search results for: Content Based Image Retrieval (CBIR)

Authors: Mamta Juneja, Parvinder S. Sandhu, Ekta Walia

Abstract:

Steganography is the process of hiding one file inside another such that others can neither identify the meaning of the embedded object, nor even recognize its existence. Current trends favor using digital image files as the cover file to hide another digital file that contains the secret message or information. One of the most common methods of implementation is Least Significant Bit Insertion, in which the least significant bit of every byte is altered to form the bit-string representing the embedded file. Altering the LSB will only cause minor changes in color, and thus is usually not noticeable to the human eye. While this technique works well for 24-bit color image files, steganography has not been as successful when using an 8-bit color image file, due to limitations in color variations and the use of a colormap. This paper presents the results of research investigating the combination of image compression and steganography. The technique developed starts with a 24-bit color bitmap file, then compresses the file by organizing and optimizing an 8-bit colormap. After the process of compression, a text message is hidden in the final, compressed image. Results indicate that the final technique has potential of being useful in the steganographic world.

Keywords: Compression, Colormap, Encryption, Steganographyand LSB Insertion.

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Authors: P. Strakos, M. Jaros, T. Karasek, T. Kozubek, P. Vavra, T. Jonszta

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In medical imaging, segmentation of different areas of human body like bones, organs, tissues, etc. is an important issue. Image segmentation allows isolating the object of interest for further processing that can lead for example to 3D model reconstruction of whole organs. Difficulty of this procedure varies from trivial for bones to quite difficult for organs like liver. The liver is being considered as one of the most difficult human body organ to segment. It is mainly for its complexity, shape versatility and proximity of other organs and tissues. Due to this facts usually substantial user effort has to be applied to obtain satisfactory results of the image segmentation. Process of image segmentation then deteriorates from automatic or semi-automatic to fairly manual one. In this paper, overview of selected available software applications that can handle semi-automatic image segmentation with further 3D volume reconstruction of human liver is presented. The applications are being evaluated based on the segmentation results of several consecutive DICOM images covering the abdominal area of the human body.

Keywords: Image segmentation, semi-automatic, software, 3D volumetric reconstruction.

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Authors: Mrs.K.Kavitha, S.Arivazhagan

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A spatial classification technique incorporating a State of Art Feature Extraction algorithm is proposed in this paper for classifying a heterogeneous classes present in hyper spectral images. The classification accuracy can be improved if and only if both the feature extraction and classifier selection are proper. As the classes in the hyper spectral images are assumed to have different textures, textural classification is entertained. Run Length feature extraction is entailed along with the Principal Components and Independent Components. A Hyperspectral Image of Indiana Site taken by AVIRIS is inducted for the experiment. Among the original 220 bands, a subset of 120 bands is selected. Gray Level Run Length Matrix (GLRLM) is calculated for the selected forty bands. From GLRLMs the Run Length features for individual pixels are calculated. The Principle Components are calculated for other forty bands. Independent Components are calculated for next forty bands. As Principal & Independent Components have the ability to represent the textural content of pixels, they are treated as features. The summation of Run Length features, Principal Components, and Independent Components forms the Combined Features which are used for classification. SVM with Binary Hierarchical Tree is used to classify the hyper spectral image. Results are validated with ground truth and accuracies are calculated.

Keywords: Multi-class, Run Length features, PCA, ICA, classification and Support Vector Machines.

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Authors: Adrian Samuel Limanto, Yunli Lee

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Interactive public displays give access as an innovative media to promote enhanced communication between people and information. However, digital public displays are subject to a few constraints, such as content presentation. Content presentation needs to be developed to be more interesting to attract people’s attention and motivate people to interact with the display. In this paper, we proposed idea to implement contents with interaction elements for vision-based digital public display. Vision-based techniques are applied as a sensor to detect passers-by and theme contents are suggested to attract their attention for encouraging them to interact with the announcement content. Virtual object, gesture detection and projection installation are applied for attracting attention from passers-by. Preliminary study showed positive feedback of interactive content designing towards the public display. This new trend would be a valuable innovation as delivery of announcement content and information communication through this media is proven to be more engaging.

Keywords: Digital announcement, digital public display, human-information interaction, interactive media.

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Authors: Hamed Vahdat Nejad, Hameed Reza Pourreza, Hasan Ebrahimi

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A new fuzzy filter is presented for noise reduction of images corrupted with additive noise. The filter consists of two stages. In the first stage, all the pixels of image are processed for determining noisy pixels. For this, a fuzzy rule based system associates a degree to each pixel. The degree of a pixel is a real number in the range [0,1], which denotes a probability that the pixel is not considered as a noisy pixel. In the second stage, another fuzzy rule based system is employed. It uses the output of the previous fuzzy system to perform fuzzy smoothing by weighting the contributions of neighboring pixel values. Experimental results are obtained to show the feasibility of the proposed filter. These results are also compared to other filters by numerical measure and visual inspection.

Keywords: Additive noise, Fuzzy logic, Image processing, Noise reduction.

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Authors: Sanghoon Kim, Sun-Tae Chung, Souhwan Jung, Dusik Oh, Jaemin Kim, Seongwon Cho

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Eye localization is necessary for face recognition and related application areas. Most of eye localization algorithms reported so far still need to be improved about precision and computational time for successful applications. In this paper, we propose an eye location method based on multi-scale Gabor feature vectors, which is more robust with respect to initial points. The eye localization based on Gabor feature vectors first needs to constructs an Eye Model Bunch for each eye (left or right eye) which consists of n Gabor jets and average eye coordinates of each eyes obtained from n model face images, and then tries to localize eyes in an incoming face image by utilizing the fact that the true eye coordinates is most likely to be very close to the position where the Gabor jet will have the best Gabor jet similarity matching with a Gabor jet in the Eye Model Bunch. Similar ideas have been already proposed in such as EBGM (Elastic Bunch Graph Matching). However, the method used in EBGM is known to be not robust with respect to initial values and may need extensive search range for achieving the required performance, but extensive search ranges will cause much more computational burden. In this paper, we propose a multi-scale approach with a little increased computational burden where one first tries to localize eyes based on Gabor feature vectors in a coarse face image obtained from down sampling of the original face image, and then localize eyes based on Gabor feature vectors in the original resolution face image by using the eye coordinates localized in the coarse scaled image as initial points. Several experiments and comparisons with other eye localization methods reported in the other papers show the efficiency of our proposed method.

Keywords: Eye Localization, Gabor features, Multi-scale, Gabor wavelets.

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Authors: Sangbum Park, Namki Lee, Youngjoon Han, Hernsoo Hahn

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In this paper, we propose the robust water level detection method based on the accumulated histogram under small changed image which is acquired from water level surveillance camera. In general surveillance system, this is detecting and recognizing invasion from searching area which is in big change on the sequential images. However, in case of a water level detection system, these general surveillance techniques are not suitable due to small change on the water surface. Therefore the algorithm introduces the accumulated histogram which is emphasizing change of water surface in sequential images. Accumulated histogram is based on the current image frame. The histogram is cumulating differences between previous images and current image. But, these differences are also appeared in the land region. The band pass filter is able to remove noises in the accumulated histogram Finally, this algorithm clearly separates water and land regions. After these works, the algorithm converts from the water level value on the image space to the real water level on the real space using calibration table. The detected water level is sent to the host computer with current image. To evaluate the proposed algorithm, we use test images from various situations.

Keywords: accumulated histogram, water level detection, band pass filter.

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Authors: Nahla Ibraheem Jabbar, Monica Mehrotra

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This paper used a fuzzy kohonen neural network for medical image segmentation. Image segmentation plays a important role in the many of medical imaging applications by automating or facilitating the diagnostic. The paper analyses the tumor by extraction of the features of (area, entropy, means and standard deviation).These measurements gives a description for a tumor.

Keywords: FCM, features extraction, medical image processing, neural network, segmentation.

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Authors: Hichem Talbi, Mohamed Batouche, Amer Draa

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In this paper we present a new approach to deal with image segmentation. The fact that a single segmentation result do not generally allow a higher level process to take into account all the elements included in the image has motivated the consideration of image segmentation as a multiobjective optimization problem. The proposed algorithm adopts a split/merge strategy that uses the result of the k-means algorithm as input for a quantum evolutionary algorithm to establish a set of non-dominated solutions. The evaluation is made simultaneously according to two distinct features: intra-region homogeneity and inter-region heterogeneity. The experimentation of the new approach on natural images has proved its efficiency and usefulness.

Keywords: Image segmentation, multiobjective optimization, quantum computing, evolutionary algorithms.

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Authors: Pengfei Xiong, Lei Huang, Changping Liu

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In illumination variant face recognition, existing methods extracting face albedo as light normalized image may lead to loss of extensive facial details, with light template discarded. To improve that, a novel approach for realistic facial texture reconstruction by combining original image and albedo image is proposed. First, light subspaces of different identities are established from the given reference face images; then by projecting the original and albedo image into each light subspace respectively, texture reference images with corresponding lighting are reconstructed and two texture subspaces are formed. According to the projections in texture subspaces, facial texture with normal light can be synthesized. Due to the combination of original image, facial details can be preserved with face albedo. In addition, image partition is applied to improve the synthesization performance. Experiments on Yale B and CMUPIE databases demonstrate that this algorithm outperforms the others both in image representation and in face recognition.

Keywords: texture reconstruction, illumination, face recognition, subspaces

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Authors: Won-Hee Cho, GeunHyung Lee, Deok-Hwan Kim

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The flash memory has many advantages such as low power consumption, strong shock resistance, fast I/O and non-volatility. And it is increasingly used in the mobile storage device. The YAFFS, one of the NAND flash file system, is widely used in the embedded device. However, the existing YAFFS takes long time to mount the file system because it scans whole spare areas in all pages of NAND flash memory. In order to solve this problem, we propose a new content-based flash file system using a mounting time reduction technique. The proposed method only scans partial spare areas of some special pages by using content-based block management. The experimental results show that the proposed method reduces the average mounting time by 87.2% comparing with JFFS2 and 69.9% comparing with YAFFS.

Keywords: NAND Flash Memory, Mounting Time, YAFFS, JFFS2, Content-based Block management

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Authors: SeHun Lim, Sanghoon Kim, Sun-Tae Chung, Seongwon Cho

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Face authentication for access control is a face membership authentication which passes the person of the incoming face if he turns out to be one of an enrolled person based on face recognition or rejects if not. Face membership authentication belongs to the two class classification problem where SVM(Support Vector Machine) has been successfully applied and shows better performance compared to the conventional threshold-based classification. However, most of previous SVMs have been trained using image feature vectors extracted from face images of each class member(enrolled class/unenrolled class) so that they are not robust to variations in illuminations, poses, and facial expressions and much affected by changes in member configuration of the enrolled class In this paper, we propose an effective face membership authentication method based on SVM using class discriminating features which represent an incoming face image-s associability with each class distinctively. These class discriminating features are weakly related with image features so that they are less affected by variations in illuminations, poses and facial expression. Through experiments, it is shown that the proposed face membership authentication method performs better than the threshold rule-based or the conventional SVM-based authentication methods and is relatively less affected by changes in member size and membership.

Keywords: Face Authentication, Access control, member ship authentication, SVM.

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Authors: V.R.Vijaykumar, P.T.Vanathi, P.Kanagasabapathy, D.Ebenezer

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In this paper, a robust statistics based filter to remove salt and pepper noise in digital images is presented. The function of the algorithm is to detect the corrupted pixels first since the impulse noise only affect certain pixels in the image and the remaining pixels are uncorrupted. The corrupted pixels are replaced by an estimated value using the proposed robust statistics based filter. The proposed method perform well in removing low to medium density impulse noise with detail preservation upto a noise density of 70% compared to standard median filter, weighted median filter, recursive weighted median filter, progressive switching median filter, signal dependent rank ordered mean filter, adaptive median filter and recently proposed decision based algorithm. The visual and quantitative results show the proposed algorithm outperforms in restoring the original image with superior preservation of edges and better suppression of impulse noise

Keywords: Image denoising, Nonlinear filter, Robust Statistics, and Salt and Pepper Noise.

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Authors: Ayman A. Aly, Abdallah A. Alshnnaway

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The general idea behind the filter is to average a pixel using other pixel values from its neighborhood, but simultaneously to take care of important image structures such as edges. The main concern of the proposed filter is to distinguish between any variations of the captured digital image due to noise and due to image structure. The edges give the image the appearance depth and sharpness. A loss of edges makes the image appear blurred or unfocused. However, noise smoothing and edge enhancement are traditionally conflicting tasks. Since most noise filtering behaves like a low pass filter, the blurring of edges and loss of detail seems a natural consequence. Techniques to remedy this inherent conflict often encompass generation of new noise due to enhancement. In this work a new fuzzy filter is presented for the noise reduction of images corrupted with additive noise. The filter consists of three stages. (1) Define fuzzy sets in the input space to computes a fuzzy derivative for eight different directions (2) construct a set of IFTHEN rules by to perform fuzzy smoothing according to contributions of neighboring pixel values and (3) define fuzzy sets in the output space to get the filtered and edged image. Experimental results are obtained to show the feasibility of the proposed approach with two dimensional objects.

Keywords: Additive noise, edge preserving filtering, fuzzy image filtering, noise reduction, two dimensional mechanical images.

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Authors: Shiraz Ahmad, Zhe-Ming Lu

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An effective visual error concealment method has been presented by employing a robust rotation, scale, and translation (RST) invariant partial patch matching model (RSTI-PPMM) and exemplar-based inpainting. While the proposed robust and inherently feature-enhanced texture synthesis approach ensures the generation of excellent and perceptually plausible visual error concealment results, the outlier pruning property guarantees the significant quality improvements, both quantitatively and qualitatively. No intermediate user-interaction is required for the pre-segmented media and the presented method follows a bootstrapping approach for an automatic visual loss recovery and the image and video error concealment.

Keywords: Exemplar-based image and video inpainting, outlierpruning, RST-invariant partial patch matching model (RSTI-PPMM), visual error concealment.

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Authors: Youngseok Kim, Chul Park, Jonghwa Yi, Sangsik Choi

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The 2-MHz Side Scan SONAR (SSS) attached to the boat for inspection of underwater structures is affected by shaking. It is difficult to determine the exact scale of damage of structure. In this study, a motion sensor is attached to the inside of the 2-MHz SSS to get roll, pitch, and yaw direction data, and developed the image stabilization tool to correct the sonar image. We checked that reliable data can be obtained with an average error rate of 1.99% between the measured value and the actual distance through experiment. It is possible to get the accurate sonar data to inspect damage in underwater structure.

Keywords: Image stabilization, motion sensor, safety inspection, sonar image, underwater structure.

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Authors: Aicha Majda, Abdelhamid El Hassani

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Lung CT image segmentation is a prerequisite in lung CT image analysis. Most of the conventional methods need a post-processing to deal with the abnormal lung CT scans such as lung nodules or other lesions. The simplest similarity measure in the standard Graph Cuts Algorithm consists of directly comparing the pixel values of the two neighboring regions, which is not accurate because this kind of metrics is extremely sensitive to minor transformations such as noise or other artifacts problems. In this work, we propose an improved version of the standard graph cuts algorithm based on the Patch-Based similarity metric. The boundary penalty term in the graph cut algorithm is defined Based on Patch-Based similarity measurement instead of the simple intensity measurement in the standard method. The weights between each pixel and its neighboring pixels are Based on the obtained new term. The graph is then created using theses weights between its nodes. Finally, the segmentation is completed with the minimum cut/Max-Flow algorithm. Experimental results show that the proposed method is very accurate and efficient, and can directly provide explicit lung regions without any post-processing operations compared to the standard method.

Keywords: Graph cuts, lung CT scan, lung parenchyma segmentation, patch based similarity metric.

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Authors: Khunsa Fatima, Umar K. Khattak, Allah Bakhsh Kausar

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Satellite images interpretation and analysis assist geologists by providing valuable information about geology and minerals of an area to be surveyed. A test site in Fatejang of district Attock has been studied using Landsat ETM+ and ASTER satellite images for lithological mapping. Five different supervised image classification techniques namely maximum likelihood, parallelepiped, minimum distance to mean, mahalanobis distance and spectral angle mapper have been performed upon both satellite data images to find out the suitable classification technique for lithological mapping in the study area. Results of these five image classification techniques were compared with the geological map produced by Geological Survey of Pakistan. Result of maximum likelihood classification technique applied on ASTER satellite image has highest correlation of 0.66 with the geological map. Field observations and XRD spectra of field samples also verified the results. A lithological map was then prepared based on the maximum likelihood classification of ASTER satellite image.

Keywords: ASTER, Landsat-ETM+, Satellite, Image classification.

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Authors: Randa Boukhris Trabelsi, Alima Damak Masmoudi, Dorra Sellami Masmoudi

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Nowadays, hand vein recognition has attracted more attentions in identification biometrics systems. Generally, hand vein image is acquired with low contrast and irregular illumination. Accordingly, if you have a good preprocessing of hand vein image, we can easy extracted the feature extraction even with simple binarization. In this paper, a proposed approach is processed to improve the quality of hand vein image. First, a brief survey on existing methods of enhancement is investigated. Then a Radon Like features method is applied to preprocessing hand vein image. Finally, experiments results show that the proposed method give the better effective and reliable in improving hand vein images.

Keywords: Hand Vein, Enhancement, Contrast, RLF, SDME

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Authors: Ibrahim A. El rube, Mohamad Abou El Nasr , Mostafa M. Naim, Mahmoud Farouk

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In this paper, a watermarking algorithm that uses the wavelet transform with Multiple Description Coding (MDC) and Quantization Index Modulation (QIM) concepts is introduced. Also, the paper investigates the role of Contourlet Transform (CT) versus Wavelet Transform (WT) in providing robust image watermarking. Two measures are utilized in the comparison between the waveletbased and the contourlet-based methods; Peak Signal to Noise Ratio (PSNR) and Normalized Cross-Correlation (NCC). Experimental results reveal that the introduced algorithm is robust against different attacks and has good results compared to the contourlet-based algorithm.

Keywords: image watermarking; discrete wavelet transform, discrete contourlet transform, multiple description coding, quantization index modulation

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Authors: Yen-Yu Chen, Pao-Ching Chu, Ya-Ling Tsai

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The algorithm represents the DCT coefficients to concentrate signal energy and proposes combination and dictator to eliminate the correlation in the same level subband for encoding the DCT-based images. This work adopts DCT and modifies the SPIHT algorithm to encode DCT coefficients. The proposed algorithm also provides the enhancement function in low bit rate in order to improve the perceptual quality. Experimental results indicate that the proposed technique improves the quality of the reconstructed image in terms of both PSNR and the perceptual results close to JPEG2000 at the same bit rate.

Keywords: JPEG 2000, enhancement filter

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Authors: Anindya Roy, Goutam Saha

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Rapid progress in audio compression technology has contributed to the explosive growth of music available in digital form today. In a reversal of ideas, this work makes use of a recently proposed efficient audio compression scheme to develop three important applications in the context of Music Information Retrieval (MIR) for the effective manipulation of large music databases, namely automatic music recommendation (AMR), digital rights management (DRM) and audio finger-printing for song identification. The performance of these three applications has been evaluated with respect to a database of songs collected from a diverse set of genres.

Keywords: Audio compression, Music Information Retrieval, Digital Rights Management, Audio Fingerprinting.

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Authors: Sadi Vural, Hiromi Tomii, Hironori Yamauchi

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As the development of digital technology is increasing, Digital cinema is getting more spread. However, content copy and attack against the digital cinema becomes a serious problem. To solve the above security problem, we propose “Additional Watermarking" for digital cinema delivery system. With this proposed “Additional watermarking" method, we protect content copyrights at encoder and user side information at decoder. It realizes the traceability of the watermark embedded at encoder. The watermark is embedded into the random-selected frames using Hash function. Using it, the embedding position is distributed by Hash Function so that third parties do not break off the watermarking algorithm. Finally, our experimental results show that proposed method is much better than the convenient watermarking techniques in terms of robustness, image quality and its simple but unbreakable algorithm.

Keywords: Decoder, Digital content, JPEG2000 Frame, System-On-Chip and additional watermark.

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Authors: Zaynab Elkhattabi, Youness Tabii, Abdelhamid Benkaddour

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Nowadays, huge amount of multimedia repositories make the browsing, retrieval and delivery of video contents very slow and even difficult tasks. Video summarization has been proposed to improve faster browsing of large video collections and more efficient content indexing and access. In this paper, we focus on approaches to video summarization. The video summaries can be generated in many different forms. However, two fundamentals ways to generate summaries are static and dynamic. We present different techniques for each mode in the literature and describe some features used for generating video summaries. We conclude with perspective for further research.

Keywords: Semantic features, static summarization, video skimming, Video summarization.

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Authors: H. B. Kekre, Tanuja K. Sarode, Bhakti Raul

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In this paper we propose segmentation approach based on Vector Quantization technique. Here we have used Kekre-s fast codebook generation algorithm for segmenting low-altitude aerial image. This is used as a preprocessing step to form segmented homogeneous regions. Further to merge adjacent regions color similarity and volume difference criteria is used. Experiments performed with real aerial images of varied nature demonstrate that this approach does not result in over segmentation or under segmentation. The vector quantization seems to give far better results as compared to conventional on-the-fly watershed algorithm.

Keywords: Image Segmentation, , Codebook, Codevector, data compression, Encoding

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Authors: Shiuh-Jer Huang, Chen-Zon Yan, C. K. Huang, Chun-Chien Ting

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Since the vision system application in industrial environment for autonomous purposes is required intensely, the image recognition technique becomes an important research topic. Here, deep learning algorithm is employed in image system to recognize the industrial object and integrate with a 7A6 Series Manipulator for object automatic gripping task. PC and Graphic Processing Unit (GPU) are chosen to construct the 3D Vision Recognition System. Depth Camera (Intel RealSense SR300) is employed to extract the image for object recognition and coordinate derivation. The YOLOv2 scheme is adopted in Convolution neural network (CNN) structure for object classification and center point prediction. Additionally, image processing strategy is used to find the object contour for calculating the object orientation angle. Then, the specified object location and orientation information are sent to robotic controller. Finally, a six-axis manipulator can grasp the specific object in a random environment based on the user command and the extracted image information. The experimental results show that YOLOv2 has been successfully employed to detect the object location and category with confidence near 0.9 and 3D position error less than 0.4 mm. It is useful for future intelligent robotic application in industrial 4.0 environment.

Keywords: Deep learning, image processing, convolution neural network, YOLOv2, 7A6 series manipulator.

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Authors: P. Mohamed Fathimal, P. Arockia Jansi Rani

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In this era of online communication, which transacts data in 0s and 1s, confidentiality is a priced commodity. Ensuring safe transmission of encrypted data and their uncorrupted recovery is a matter of prime concern. Among the several techniques for secure sharing of images, this paper proposes a k out of n region incrementing image sharing scheme for color images. The highlight of this scheme is the use of simple Boolean and arithmetic operations for generating shares and the Lagrange interpolation polynomial for authenticating shares. Additionally, this scheme addresses problems faced by existing algorithms such as color reversal and pixel expansion. This paper regenerates the original secret image whereas the existing systems regenerates only the half toned secret image.

Keywords: Threshold Secret Sharing Scheme, Access Control, Steganography, Authentication, Secret Image Sharing, XOR, Pixel Expansion.

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Authors: Rajlaxmi Chouhan, Pritee Khanna

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In this manuscript, a wavelet-based blind watermarking scheme has been proposed as a means to provide security to authenticity of a fingerprint. The information used for identification or verification of a fingerprint mainly lies in its minutiae. By robust watermarking of the minutiae in the fingerprint image itself, the useful information can be extracted accurately even if the fingerprint is severely degraded. The minutiae are converted in a binary watermark and embedding these watermarks in the detail regions increases the robustness of watermarking, at little to no additional impact on image quality. It has been experimentally shown that when the minutiae is embedded into wavelet detail coefficients of a fingerprint image in spread spectrum fashion using a pseudorandom sequence, the robustness is observed to have a proportional response while perceptual invisibility has an inversely proportional response to amplification factor “K". The DWT-based technique has been found to be very robust against noises, geometrical distortions filtering and JPEG compression attacks and is also found to give remarkably better performance than DCT-based technique in terms of correlation coefficient and number of erroneous minutiae.

Keywords: Fingerprint watermarking, minutiae, discrete wavelet transform, PN sequence

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Authors: Yayun Hsu, Henry Horng-Shing Lu

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This paper proposes a data-driven, biology-inspired neural segmentation method of 3D drosophila Brainbow images. We use Bayesian Sequential Partitioning algorithm for probabilistic modeling, which can be used to detect somas and to eliminate crosstalk effects. This work attempts to develop an automatic methodology for neuron image segmentation, which nowadays still lacks a complete solution due to the complexity of the image. The proposed method does not need any predetermined, risk-prone thresholds, since biological information is inherently included inside the image processing procedure. Therefore, it is less sensitive to variations in neuron morphology; meanwhile, its flexibility would be beneficial for tracing the intertwining structure of neurons.

Keywords: Brainbow, 3D imaging, image segmentation, neuron morphology, biological data mining, non-parametric learning.

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Authors: Yasuyuki Takahashi, Hayato Ishimura, Masao Miyagawa, Teruhito Mochizuki

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Quantitative measurement of myocardium perfusion is possible with single photon emission computed tomography (SPECT) using a semiconductor detector. However, accumulation of ^99mTc-tetrofosmin in the liver may make it difficult to assess that accurately in the inferior myocardium. Our idea is to reduce the high accumulation in the liver by using dynamic SPECT imaging and a technique called time subtraction. We evaluated the performance of a new SPECT system with a cadmium-zinc-telluride solid-state semi- conductor detector (Discovery NM 530c; GE Healthcare). Our system acquired list-mode raw data over 10 minutes for a typical patient. From the data, ten SPECT images were reconstructed, one for every minute of acquired data. Reconstruction with the semiconductor detector was based on an implementation of a 3-D iterative Bayesian reconstruction algorithm. We studied 20 patients with coronary artery disease (mean age 75.4 ± 12.1 years; range 42-86; 16 males and 4 females). In each subject, 259 MBq of ^99mTc-tetrofosmin was injected intravenously. We performed both a phantom and a clinical study using dynamic SPECT. An approximation to a liver-only image is obtained by reconstructing an image from the early projections during which time the liver accumulation dominates (0.5~2.5 minutes SPECT image-5~10 minutes SPECT image). The extracted liver-only image is then subtracted from a later SPECT image that shows both the liver and the myocardial uptake (5~10 minutes SPECT image-liver-only image). The time subtraction of liver was possible in both a phantom and the clinical study. The visualization of the inferior myocardium was improved. In past reports, higher accumulation in the myocardium due to the overlap of the liver is un-diagnosable. Using our time subtraction method, the image quality of the ^99mTc-tetorofosmin myocardial SPECT image is considerably improved.

Keywords: 99mTc-tetrofosmin, dynamic SPECT, time subtraction, semiconductor detector.

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