Search results for: axial derivative
419 Investigation of Unconventional Fuels in Co-Axial Engines
Authors: Arya Pirooz
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The effects of different fuels (DME, RME B100, and SME B100) on barrel engines were studied as a general, single dimensional investigation for characterization of these types of engines. A base computational model was created as reference point to be used as a point of comparison with different cases. The models were computed using the commercial computational fluid dynamics program, Diesel-RK. The base model was created using basic dimensions of the PAMAR-3 engine with inline unit injectors. Four fuel cases were considered. Optimized models were also considered for diesel and DME cases with respect to injection duration, fuel, injection timing, exhaust and intake port opening, CR, angular offset. These factors were optimized for highest BMEP, combined PM and NOx emissions, and highest SFC. Results included mechanical efficiency (eta_m), efficiency and power, emission characteristics, combustion characteristics. DME proved to have the highest performing characteristics in relation to diesel and RME fuels for this type of barrel engine.Keywords: DME, RME, Diesel-RK, characterization, inline unit injector
Procedia PDF Downloads 465418 Moment-Curvature Relation for Nonlinear Analysis of Slender Structural Walls
Authors: E. Dehghan, R. Dehghan
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Generally, the slender structural walls have flexural behavior. Since behavior of bending members can be explained by moment–curvature relation, therefore, an analytical model is proposed based on moment–curvature relation for slender structural walls. The moment–curvature relationships of RC sections are constructed through section analysis. Governing equations describing the bond-slip behavior in walls are derived and applied to moment–curvature relations. For the purpose of removing the imprecision in analytical results, the plastic hinge length is included in the finite element modeling. Finally, correlation studies between analytical and experimental results are conducted with the objective to establish the validity of the proposed algorithms. The results show that bond-slip effect is more significant in walls subjected to larger axial compression load. Moreover, preferable results are obtained when ultimate strain of concrete is assumed conservatively.Keywords: nonlinear analysis, slender structural walls, moment-curvature relation, bond-slip, plastic hinge length
Procedia PDF Downloads 305417 Advanced Eales’ Disease with Neovascular Glaucoma at First Presentation: Case Report
Authors: Mohammed A. Alfayyadh, Halla A. AlAbdulhadi, Mahdi H. Almubarak
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Purpose: Eales’ disease is an idiopathic vasculitis that affects the peripheral retina. It is characterized by recurrent vitreous hemorrhage as a complication of retinal neovascularization. It is more prevalent in India and affects young males. Here we present a patient with neovascular glaucoma as a rare first presentation of Eales’ disease. Observations: This is a 24-year-old Indian gentleman, who complained of a sudden decrease in vision in the left eye over less than 24 hours, along with frontal headache and eye pain for the last three weeks. Ocular examination revealed peripheral retinal ischemia in the right eye, very high intraocular pressure, rubeosis iridis, vitreous hemorrhage and extensive retinal ischemia in the left eye, vascular sheathing and neovascularization in both eyes. Purified protein derivative skin test was positive. The patient was managed with anti-glaucoma, intravitreal anti-vascular endothelial growth factor and laser photocoagulation. Systemic steroids and anti-tuberculous therapy were also initiated. Conclusions: Neovascular glaucoma is an infrequent complication of Eales’ disease. However, the lack of early detection of the disease in the early stages might lead to such serious complication.Keywords: case report, Eales’ disease, mycobacterium tuberculosis, neovascular glaucoma
Procedia PDF Downloads 119416 Hysteretic Behavior of the Precast Concrete Column with Head Splice Sleeve Connection
Authors: Seo Soo-Yeon, Kim Sang-Ku, Noh Sang-Hyun, Lee Ji-Eun, Kim Seol-Ki, Lim Jong-Wook
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This paper presents a test result to find the structural capacity of Hollow-Precast Concrete (HPC) column with Head-Splice Sleeve (HSS) for the connection of bars under horizontal cyclic load. Two Half-scaled HPC column specimens were made with the consideration of construction process in site. The difference between the HPC specimens is the location of HSS for bar connection. The location of the first one is on the bottom slab or foundation while the other is above the bottom slab or foundation. Reinforced concrete (RC) column was also made for the comparison. In order to evaluate the hysteretic behavior of the specimens, horizontal cyclic load was applied to the top of specimen under constant axial load. From the test, it is confirmed that the HPC columns with HSS have enough structural capacity that can be emulated to RC column. This means that the HPC column with HSS can be used in the moment resisting frame system.Keywords: structural capacity, hollow-precast concrete column, head-splice sleeve, horizontal cyclic load
Procedia PDF Downloads 361415 Improve Closed Loop Performance and Control Signal Using Evolutionary Algorithms Based PID Controller
Authors: Mehdi Shahbazian, Alireza Aarabi, Mohsen Hadiyan
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Proportional-Integral-Derivative (PID) controllers are the most widely used controllers in industry because of its simplicity and robustness. Different values of PID parameters make different step response, so an increasing amount of literature is devoted to proper tuning of PID controllers. The problem merits further investigation as traditional tuning methods make large control signal that can damages the system but using evolutionary algorithms based tuning methods improve the control signal and closed loop performance. In this paper three tuning methods for PID controllers have been studied namely Ziegler and Nichols, which is traditional tuning method and evolutionary algorithms based tuning methods, that are, Genetic algorithm and particle swarm optimization. To examine the validity of PSO and GA tuning methods a comparative analysis of DC motor plant is studied. Simulation results reveal that evolutionary algorithms based tuning method have improved control signal amplitude and quality factors of the closed loop system such as rise time, integral absolute error (IAE) and maximum overshoot.Keywords: evolutionary algorithm, genetic algorithm, particle swarm optimization, PID controller
Procedia PDF Downloads 471414 Free Vibration Analysis of Conical Helicoidal Rods Having Elliptical Cross Sections Positioned in Different Orientation
Authors: Merve Ermis, Akif Kutlu, Nihal Eratlı, Mehmet H. Omurtag
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In this study, the free vibration analysis of conical helicoidal rods with two different elliptically oriented cross sections is investigated and the results are compared by the circular cross-section keeping the net area for all cases equal to each other. Problems are solved by using the mixed finite element formulation. Element matrices based on Timoshenko beam theory are employed. The finite element matrices are derived by directly inserting the analytical expressions (arc length, curvature, and torsion) defining helix geometry into the formulation. Helicoidal rod domain is discretized by a two-noded curvilinear element. Each node of the element has 12 DOFs, namely, three translations, three rotations, two shear forces, one axial force, two bending moments and one torque. A parametric study is performed to investigate the influence of elliptical cross sectional geometry and its orientation over the natural frequencies of the conical type helicoidal rod.Keywords: conical helix, elliptical cross section, finite element, free vibration
Procedia PDF Downloads 303413 4(3H)-Quinazolinone Derivatives' Synthesis and Evaluation as Antimalarial and Anti-Leishmanial Agents
Authors: Alemu Tadesse Feroche
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In this study, some 2, 3 distributed quinazoline -4 (3H) - one derivative were synthesized using a three-step synthetic route. They were obtained in a good yield (59.5-85%) by applying different chemical reactions like cyclization and condensation reactions. The chemical structure of the final compounds was also verified by spectroscopic methods (IR, ¹HNMR) and elemental microanalysis. The in vivo antimalarial activity of these compounds on P. berghei infected mice was found to be moderate to high at an oral dose of 0.04846 mmol/kg /day. This is equal to 25 mg/kg of chloroquine phosphate, which causes 100% inhibition of the parasite. It is worth mentioning that most active compounds (E) -3 Phenyl -2- [2- (pyridine -4- yl) vinyl] -4 (3H) -quinazolinone IVa (64.02%, (E)-2-[2-(4 - Hydroxy-3 - methoxystyryl) - vinyl) -3 - phenyl -4 (3H ) - quinazolinone IVc (77.25%) and (E)-2 –[2 –(Pyridin -4-yl) –vinyl] -3 phenenylamine -4(3H) quinazolinone IVe (73.54%) showed a dose-dependent increase in present suppression in antimalarial activities. Furthermore, the synthesized compounds were screened for their in vitro antileishmanial activity against L. aethiopica isolate (CL/039/09). All tested compounds (IVa (0.03766 ug/ml), IVb (0.00538 ug/ml, IVc (0.00412 ug/ml, IVd (0.00110 ug/ml), IVe (0.03017 ug/ml) and IVf (0.03894 ug/ml)) showed excellent potency that is much better than amphotericin B (IC50 = 0,04359 ug/ml). The results of acute toxicity indicated that all test compounds (IVa –IVf) proved to be nontoxic and well tolerated by the experimental animals up to 300 mg/kg in oral and 140 mg/kg in parental studies.Keywords: 4(3H)-quinazolinone, in vivo antimalarial activity, in vitro antileishmanial activity, acute toxicity
Procedia PDF Downloads 93412 Studying Frame-Resistant Steel Structures under Near Field Ground Motion
Authors: S. A. Hashemi, A. Khoshraftar
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This paper presents the influence of the vertical seismic component on the non-linear dynamics analysis of three different structures. The subject structures were analyzed and designed according to recent codes. This paper considers three types of buildings: 5-, 10-, and 15-story buildings. The non-linear dynamics analysis of the structures with assuming elastic-perfectly-plastic behavior was performed using Ram Perform-3D software; the horizontal component was taken into consideration with and without the incorporation of the corresponding vertical component. Dynamic responses obtained for the horizontal component acting alone were compared with those obtained from the simultaneous application of both seismic components. The results show that the effect of the vertical component of the ground motion may increase the axial load significantly in the interior columns and consequently, the stories. The plastic mechanisms would be changed. The P-Delta effect is expected to increase. The punching base plate shear of the columns should be considered. Moreover, the vertical component increases the input energy when the structures exhibit inelastic behavior and are taller.Keywords: inelastic behavior, non-linear dynamic analysis, steel structure, vertical component
Procedia PDF Downloads 305411 Study of Two MPPTs for Photovoltaic Systems Using Controllers Based in Fuzzy Logic and Sliding Mode
Authors: N. Ould cherchali, M. S. Boucherit, L. Barazane, A. Morsli
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Photovoltaic power is widely used to supply isolated or unpopulated areas (lighting, pumping, etc.). Great advantage is that this source is inexhaustible, it offers great safety in use and it is clean. But the dynamic models used to describe a photovoltaic system are complicated and nonlinear and due to nonlinear I-V and P–V characteristics of photovoltaic generators, a maximum power point tracking technique (MPPT) is required to maximize the output power. In this paper, two online techniques of maximum power point tracking using robust controller for photovoltaic systems are proposed, the first technique use fuzzy logic controller (FLC) and the second use sliding mode controller (SMC) for photovoltaic systems. The two maximum power point tracking controllers receive the partial derivative of power as inputs, and the output is the duty cycle corresponding to maximum power. A Photovoltaic generator with Boost converter is developed using MATLAB/Simulink to verify the preferences of the proposed techniques. SMC technique provides a good tracking speed in fast changing irradiation and when the irradiation changes slowly or is constant the panel power of FLC technique presents a much smoother signal with less fluctuations.Keywords: fuzzy logic controller, maximum power point, photovoltaic system, tracker, sliding mode controller
Procedia PDF Downloads 536410 Cyclic Loading Tests of Reinforced Concrete Frame Structures Strengthened by Externally-Anchored Precast Wall-Panel
Authors: Seung-Ho Choi, Jae Yuel Oh, Chi Sung Lim, Ho Seong Jung, Kang Su Kim
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In recent years, various strengthening methods for buildings have been developed, but most of them require quite a long construction period during which the building users need to be patient on uncomfortable working environments including various lousy noises or even evacuation of the buildings. In this study, externally anchored precast wall-panel method (EPCW) for strengthening non-seismic reinforced concrete (RC) structures has been proposed, which is occupant-friendly technique because the strengthening walls are manufactured at factory and can be tightened to the members very quickly at the site. In order to investigate the structural performance of the specimens strengthened by the EPCW method, a total of four specimens were fabricated, and tested under axial and reversed cyclic lateral loads. The test results showed that the lateral resistances of the specimens strengthened by the EPCW method were greatly enhanced in both positive and negative directions, compared to the RC specimen having non-seismic details.Keywords: precast wall, seismic strengthening, reinforced concrete, externally-anchored
Procedia PDF Downloads 289409 Performance Comparisons between PID and Adaptive PID Controllers for Travel Angle Control of a Bench-Top Helicopter
Authors: H. Mansor, S. B. Mohd-Noor, T. S. Gunawan, S. Khan, N. I. Othman, N. Tazali, R. B. Islam
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This paper provides a comparative study on the performances of standard PID and adaptive PID controllers tested on travel angle of a 3-Degree-of-Freedom (3-DOF) Quanser bench-top helicopter. Quanser, a well-known manufacturer of educational bench-top helicopter has developed Proportional Integration Derivative (PID) controller with Linear Quadratic Regulator (LQR) for all travel, pitch and yaw angle of the bench-top helicopter. The performance of the PID controller is relatively good; however its performance could also be improved if the controller is combined with adaptive element. The objective of this research is to design adaptive PID controller and then compare the performances of the adaptive PID with the standard PID. The controller design and test is focused on travel angle control only. Adaptive method used in this project is self-tuning controller, which controller’s parameters are updated online. Two adaptive algorithms those are pole-placement and deadbeat have been chosen as the method to achieve optimal controller’s parameters. Performance comparisons have shown that the adaptive (deadbeat) PID controller has produced more desirable performance compared to standard PID and adaptive (pole-placement). The adaptive (deadbeat) PID controller attained very fast settling time (5 seconds) and very small percentage of overshoot (5% to 7.5%) for 10° to 30° step change of travel angle.Keywords: adaptive control, deadbeat, pole-placement, bench-top helicopter, self-tuning control
Procedia PDF Downloads 490408 Analysis of Vibratory Signals Based on Local Mean Decomposition (LMD) for Rolling Bearing Fault Diagnosis
Authors: Toufik Bensana, Medkour Mihoub, Slimane Mekhilef
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The use of vibration analysis has been established as the most common and reliable method of analysis in the field of condition monitoring and diagnostics of rotating machinery. Rolling bearings cover a broad range of rotary machines and plays a crucial role in the modern manufacturing industry. Unfortunately, the vibration signals collected from a faulty bearing are generally nonstationary, nonlinear and with strong noise interference, so it is essential to obtain the fault features correctly. In this paper, a novel numerical analysis method based on local mean decomposition (LMD) is proposed. LMD decompose the signal into a series of product functions (PFs), each of which is the product of an envelope signal and a purely frequency modulated FM signal. The envelope of a PF is the instantaneous amplitude (IA), and the derivative of the unwrapped phase of a purely flat frequency demodulated (FM) signal is the IF. After that, the fault characteristic frequency of the roller bearing can be extracted by performing spectrum analysis to the instantaneous amplitude of PF component containing dominant fault information. The results show the effectiveness of the proposed technique in fault detection and diagnosis of rolling element bearing.Keywords: fault diagnosis, rolling element bearing, local mean decomposition, condition monitoring
Procedia PDF Downloads 380407 A New Phenolic Compound Isolated from Laurus nobilis from Lebanon and Comparison of Antioxidant Activity of Different Parts
Authors: Turk Ayman, Ahn Jong Hoon, Khalife K. Hala, Gali-Muhtasib Hala, Lee Mi Kyeong
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Laurus nobilis is an aromatic plant widely distributed in the Mediterranean region. The leaves of this plant are frequently used as a spice and as a traditional medicine for several diseases. In our present study, the methanolic extract of L. nobilis leaves showed antioxidant activity. Chromatographic separations of the EtOAc fraction which had the highest antioxidant activity led to the isolation of 12 compounds. Among them, there was a new phenylpropanoid derivative, which was identified by 1D and 2D NMR experiments, as well as high resolution mass spectrometry. In addition, two major compounds, catechin and epicatechin, which showed strong antioxidant activity may be responsible for the antioxidant activity of L. nobilis leaves. Since different plant parts may contain different types of constituents which contribute to the biological activities, we investigated the antioxidant activity of different parts of L. nobilis such as leaves, stems and fruits. Stems of L. nobilis showed the most potent antioxidant activity, followed by leaves. Further quantitation of total phenol and flavonoids contents revealed a positive correlation between the content of these compounds and antioxidant activity. Taken together, phenolic compounds including flavonoids are responsible for antioxidant activity of L. nobilis. In addition, stem parts of L. nobilis are suggested as good sources for antioxidant activity. Conclusively, L. nobilis might be effective in several free radical mediated diseases.Keywords: antioxidant activity, different parts, Laurus nobilis, phenolic compound
Procedia PDF Downloads 292406 Static Eccentricity Fault Diagnosis in Synchronous Reluctance Motor and Permanent Magnet Assisted Synchronous Reluctance Motor
Authors: M. Naeimi, H. Aghazadeh, E. Afjei, A. Siadatan
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In this paper, a novel view of air gap magnetic field analysis of synchronous reluctance motor and permanent magnet assisted synchronous reluctance motor under static eccentricity to provide the precise fault diagnosis based on three-dimensional finite element method is presented. Analytical nature of this method makes it possible to simulate reliable and precise model by considering the end effects and axial fringing effects. The results of the three-dimensional finite element analysis of synchronous reluctance motor and permanent magnet synchronous reluctance motor such as flux linkage, flux density, and compression both of SynRM and PM-SynRM for various eccentric motor conditions are obtained and analyzed. These results present useful information regarding to the detection of static eccentricity.Keywords: synchronous reluctance motor (SynRM), permanent magnet assisted synchronous reluctance motor (PMaSynRM), finite element method, static eccentricity, fault analysis
Procedia PDF Downloads 306405 Prediction of Concrete Hydration Behavior and Cracking Tendency Based on Electrical Resistivity Measurement, Cracking Test and ANSYS Simulation
Authors: Samaila Muazu Bawa
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Hydration process, crack potential and setting time of concrete grade C30, C40 and C50 were separately monitored using non-contact electrical resistivity apparatus, a plastic ring mould and penetration resistance method respectively. The results show highest resistivity of C30 at the beginning until reaching the acceleration point when C50 accelerated and overtaken the others, and this period corresponds to its final setting time range, from resistivity derivative curve, hydration process can be divided into dissolution, induction, acceleration and deceleration periods, restrained shrinkage crack and setting time tests demonstrated the earliest cracking and setting time of C50, therefore, this method conveniently and rapidly determines the concrete’s crack potential. The highest inflection time (ti), the final setting time (tf) were obtained and used with crack time in coming up with mathematical models for the prediction of concrete’s cracking age for the range being considered. Finally, ANSYS numerical simulations supports the experimental findings in terms of the earliest crack age of C50 and the crack location that, highest stress concentration is always beneath the artificially introduced expansion joint of C50.Keywords: concrete hydration, electrical resistivity, restrained shrinkage crack, ANSYS simulation
Procedia PDF Downloads 230404 Behavior of Double Skin Circular Tubular Steel-Concrete-Composite Column
Authors: Usha Sivasankaran, Seetha Raman
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Experimental work on Double skin Concrete Filled tubes (DSCFT) are a variation of CFT (Concrete- filled steel tubular) with a hollow core formed by two concentric steel tubes in – filled with concrete. Six Specimens with three different volume fractions of steel fibres are cast and tested. Experiments on circular steel tubes in – filled with steel fibre reinforced concrete (SFRC) and normal concrete have been performed to investigate the contribution of steel fibres to the load bearing capacity of Short Composite Columns. The main Variable considered in the test study is the percentage of steel fibres added to the in –filled concrete. All the specimens were tested under axial compression until failure state realisation. This project presents the percentage Variation in the compression strengths of the 3 types of Composite members taken under Study. The results show that 1.5% SFRC in filled steel columns exhibit enhanced ultimate load carrying capacity.Keywords: composite columns, optimization of steel, double skin, DSCFT
Procedia PDF Downloads 542403 Performance of Axially Loaded Single Pile Embedded in Cohesive Soil with Cavities
Authors: Ali A. Al-Jazaairry, Tahsin T. Sabbagh
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The stability of a single model pile located adjacent to a continuous cavity was studied. This paper is an attempt to understand the behaviour of axially loaded single pile embedded in clayey soil with the presences of cavities. The performance of piles located in such soils was studied analytically. A verification analysis was carried out on available studies to assess the ability of analytical model to correctly interpret the system behaviour. The study was adopted by finite element program (PLAXIS). The study included many cases; in each case, there is a critical value in which the presence of cavities has shown minimum effect on the pile performance. Figures including the load carrying capacity of pile with the affecting factors are presented. These figures provide beneficial information for pile design constructed close to underground cavities. It was concluded that the load carrying capacity of the pile is reduced by the presence of the cavity within the soil mass. This reduction varies according to the size and location of cavity.Keywords: axial load, cavity, clay, pile, ultimate capacity
Procedia PDF Downloads 262402 Laboratory Evaluation of Rutting and Fatigue Damage Resistance of Asphalt Mixtures Modified with Carbon Nano Tubes
Authors: Ali Zain Ul Abadeen, Arshad Hussain
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Roads are considered as the national capital, and huge developmental budget is spent on its construction, maintenance, and rehabilitation. Due to proliferating traffic volume, heavier loads and challenging environmental factors, the need for high-performance asphalt pavement is increased. In this research, the asphalt mixture was modified with carbon nanotubes ranging from 0.2% to 2% of binder to study the effect of CNT modification on rutting potential and fatigue life of asphalt mixtures. During this study, the conventional and modified asphalt mixture was subjected to a uni-axial dynamic creep test and dry Hamburg wheel tracking test to study rutting resistance. Fatigue behavior of asphalt mixture was studied using a four-point bending test apparatus. The plateau value of asphalt mixture was taken as a measure of fatigue performance according to the ratio of dissipated energy approach. Results of these experiments showed that CNT modified asphalt mixtures had reduced rut depth and increased rutting and fatigue resistance at higher percentages of carbon nanotubes.Keywords: carbon nanotubes, fatigue, four point bending test, modified asphalt, rutting
Procedia PDF Downloads 131401 Optimal Tuning of Linear Quadratic Regulator Controller Using a Particle Swarm Optimization for Two-Rotor Aerodynamical System
Authors: Ayad Al-Mahturi, Herman Wahid
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This paper presents an optimal state feedback controller based on Linear Quadratic Regulator (LQR) for a two-rotor aero-dynamical system (TRAS). TRAS is a highly nonlinear multi-input multi-output (MIMO) system with two degrees of freedom and cross coupling. There are two parameters that define the behavior of LQR controller: state weighting matrix and control weighting matrix. The two parameters influence the performance of LQR. Particle Swarm Optimization (PSO) is proposed to optimally tune weighting matrices of LQR. The major concern of using LQR controller is to stabilize the TRAS by making the beam move quickly and accurately for tracking a trajectory or to reach a desired altitude. The simulation results were carried out in MATLAB/Simulink. The system is decoupled into two single-input single-output (SISO) systems. Comparing the performance of the optimized proportional, integral and derivative (PID) controller provided by INTECO, results depict that LQR controller gives a better performance in terms of both transient and steady state responses when PSO is performed.Keywords: LQR controller, optimal control, particle swarm optimization (PSO), two rotor aero-dynamical system (TRAS)
Procedia PDF Downloads 318400 Conceptional Design of a Hyperloop Capsule with Linear Induction Propulsion System
Authors: Ahmed E. Hodaib, Samar F. Abdel Fattah
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High-speed transportation is a growing concern. To develop high-speed rails and to increase high-speed efficiencies, the idea of Hyperloop was introduced. The challenge is to overcome the difficulties of managing friction and air-resistance which become substantial when vehicles approach high speeds. In this paper, we are presenting the methodologies of the capsule design which got a design concept innovation award at SpaceX competition in January, 2016. MATLAB scripts are written for the levitation and propulsion calculations and iterations. Computational Fluid Dynamics (CFD) is used to simulate the air flow around the capsule considering the effect of the axial-flow air compressor and the levitation cushion on the air flow. The design procedures of a single-sided linear induction motor are analyzed in detail and its geometric and magnetic parameters are determined. A structural design is introduced and Finite Element Method (FEM) is used to analyze the stresses in different parts. The configuration and the arrangement of the components are illustrated. Moreover, comments on manufacturing are made.Keywords: high-speed transportation, hyperloop, railways transportation, single-sided linear induction Motor (SLIM)
Procedia PDF Downloads 271399 Ensemble Sampler For Infinite-Dimensional Inverse Problems
Authors: Jeremie Coullon, Robert J. Webber
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We introduce a Markov chain Monte Carlo (MCMC) sam-pler for infinite-dimensional inverse problems. Our sam-pler is based on the affine invariant ensemble sampler, which uses interacting walkers to adapt to the covariance structure of the target distribution. We extend this ensem-ble sampler for the first time to infinite-dimensional func-tion spaces, yielding a highly efficient gradient-free MCMC algorithm. Because our ensemble sampler does not require gradients or posterior covariance estimates, it is simple to implement and broadly applicable. In many Bayes-ian inverse problems, Markov chain Monte Carlo (MCMC) meth-ods are needed to approximate distributions on infinite-dimensional function spaces, for example, in groundwater flow, medical imaging, and traffic flow. Yet designing efficient MCMC methods for function spaces has proved challenging. Recent gradi-ent-based MCMC methods preconditioned MCMC methods, and SMC methods have improved the computational efficiency of functional random walk. However, these samplers require gradi-ents or posterior covariance estimates that may be challenging to obtain. Calculating gradients is difficult or impossible in many high-dimensional inverse problems involving a numerical integra-tor with a black-box code base. Additionally, accurately estimating posterior covariances can require a lengthy pilot run or adaptation period. These concerns raise the question: is there a functional sampler that outperforms functional random walk without requir-ing gradients or posterior covariance estimates? To address this question, we consider a gradient-free sampler that avoids explicit covariance estimation yet adapts naturally to the covariance struc-ture of the sampled distribution. This sampler works by consider-ing an ensemble of walkers and interpolating and extrapolating between walkers to make a proposal. This is called the affine in-variant ensemble sampler (AIES), which is easy to tune, easy to parallelize, and efficient at sampling spaces of moderate dimen-sionality (less than 20). The main contribution of this work is to propose a functional ensemble sampler (FES) that combines func-tional random walk and AIES. To apply this sampler, we first cal-culate the Karhunen–Loeve (KL) expansion for the Bayesian prior distribution, assumed to be Gaussian and trace-class. Then, we use AIES to sample the posterior distribution on the low-wavenumber KL components and use the functional random walk to sample the posterior distribution on the high-wavenumber KL components. Alternating between AIES and functional random walk updates, we obtain our functional ensemble sampler that is efficient and easy to use without requiring detailed knowledge of the target dis-tribution. In past work, several authors have proposed splitting the Bayesian posterior into low-wavenumber and high-wavenumber components and then applying enhanced sampling to the low-wavenumber components. Yet compared to these other samplers, FES is unique in its simplicity and broad applicability. FES does not require any derivatives, and the need for derivative-free sam-plers has previously been emphasized. FES also eliminates the requirement for posterior covariance estimates. Lastly, FES is more efficient than other gradient-free samplers in our tests. In two nu-merical examples, we apply FES to challenging inverse problems that involve estimating a functional parameter and one or more scalar parameters. We compare the performance of functional random walk, FES, and an alternative derivative-free sampler that explicitly estimates the posterior covariance matrix. We conclude that FES is the fastest available gradient-free sampler for these challenging and multimodal test problems.Keywords: Bayesian inverse problems, Markov chain Monte Carlo, infinite-dimensional inverse problems, dimensionality reduction
Procedia PDF Downloads 150398 Computational Aerodynamic Shape Optimisation Using a Concept of Control Nodes and Modified Cuckoo Search
Authors: D. S. Naumann, B. J. Evans, O. Hassan
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This paper outlines the development of an automated aerodynamic optimisation algorithm using a novel method of parameterising a computational mesh by employing user–defined control nodes. The shape boundary movement is coupled to the movement of the novel concept of the control nodes via a quasi-1D-linear deformation. Additionally, a second order smoothing step has been integrated to act on the boundary during the mesh movement based on the change in its second derivative. This allows for both linear and non-linear shape transformations dependent on the preference of the user. The domain mesh movement is then coupled to the shape boundary movement via a Delaunay graph mapping. A Modified Cuckoo Search (MCS) algorithm is used for optimisation within the prescribed design space defined by the allowed range of control node displacement. A finite volume compressible NavierStokes solver is used for aerodynamic modelling to predict aerodynamic design fitness. The resulting coupled algorithm is applied to a range of test cases in two dimensions including the design of a subsonic, transonic and supersonic intake and the optimisation approach is compared with more conventional optimisation strategies. Ultimately, the algorithm is tested on a three dimensional wing optimisation case.Keywords: mesh movement, aerodynamic shape optimization, cuckoo search, shape parameterisation
Procedia PDF Downloads 329397 Study of the Influence of Nozzle Length and Jet Angles on the Air Entrainment by Plunging Water Jets
Authors: José Luis Muñoz-Cobo González, Sergio Chiva Vicent, Khaled Harby Mohamed
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When a vertical liquid jet plunges into a liquid surface, after passing through a surrounding gas phase, it entrains a large amount of gas bubbles into the receiving pool, and it forms a large submerged two-phase region with a considerable interfacial area. At the intersection of the plunging jet and the liquid surface, free-surface instabilities are developed, and gas entrainment may be observed. If the jet impact velocity exceeds an inception velocity that is a function of the plunging flow conditions, the gas entrainment takes place. The general goal of this work is to study the effect of nozzle parameters (length-to-diameter ratio (lN/dN), jet angle (α) with the free water surface) and the jet operating conditions (initial jet diameters dN, initial jet velocity VN, and jet length x1) on the flow characteristics such as: inception velocity of the gas entrainment Ve, bubble penetration depth Hp, gas entrainment rate, Qa, centerline jet velocity Vc, and the axial jet velocity distribution Vx below the free water surface in a plunging liquid jet system.Keywords: inclined plunging water jets, entrainment, two phase flow, nozzle length
Procedia PDF Downloads 454396 Experimental Study on Aerodynamic Noise of Radiator Cooling Fan with Different Diameter in Hemi-Anechoic Chamber
Authors: Malinda Sabrina, F. Andree Yohanes, Khoerul Anwar
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There are many sources that cause noise in a car, one of them is noise from radiator cooling fan. This part is used to control engine temperature by ensuring adequate airflow through radiator. Radiator cooling fan noise is a very important matter especially for vehicle manufacturers. This can affect brand image of the car and their customer satisfaction. Therefore, some experiments to measure noise level of the fan are required. Sound pressure level measurements for two axial fans with different diameter have been investigated in a hemi-anechoic chamber based on standard JIS-B8346, focusing on aerodynamic noise. Both fans have the same profile and shape with diameter respectively 43 cm and 49 cm. The measurement was performed in hemi-anechoic chamber in order to obtain a background noise at measuring point as low as possible. Noise characterizations of these radiator cooling fans were measured in five different rotating speed and the results were compared. The measurement result shows that the sound pressure level increases with increasing rotational speed of the fan. In comparison with a smaller diameter, it is shown that fan with larger diameter produces higher noise level at the same rotational speed.Keywords: aerodynamics noise, hemi-anechoic chamber, radiator cooling fan, sound pressure level
Procedia PDF Downloads 323395 PEG-b-poly(4-vinylbenzyl phosphonate) Coated Magnetic Iron Oxide Nanoparticles as Drug Carrier System: Biological and Physicochemical Characterization
Authors: Magdalena Hałupka-Bryl, Magdalena Bednarowicz, Ryszard Krzyminiewski, Yukio Nagasaki
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Due to their unique physical properties, superparamagnetic iron oxide nanoparticles are increasingly used in medical applications. They are very useful carriers for delivering antitumor drugs in targeted cancer treatment. Magnetic nanoparticles (PEG-PIONs/DOX) with chemotherapeutic were synthesized by coprecipitation method followed by coating with biocompatible polymer PEG-derivative (poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate). Complete physicochemical characterization was carried out (ESR, HRTEM, X-ray diffraction, SQUID analysis) to evaluate the magnetic properties of obtained PEG-PIONs/DOX. Nanoparticles were investigated also in terms of their stability, drug loading efficiency, drug release and antiproliferative effect on cancer cells. PEG-PIONs/DOX have been successfully used for the efficient delivery of an anticancer drug into the tumor region. Fluorescent imaging showed the internalization of PEG-PIONs/DOX in the cytoplasm. Biodistribution studies demonstrated that PEG-PIONs/DOX preferentially accumulate in tumor region via the enhanced permeability and retention effect. The present findings show that synthesized nanosystem is promising tool for potential magnetic drug delivery.Keywords: targeted drug delivery, magnetic properties, iron oxide nanoparticles, biodistribution
Procedia PDF Downloads 457394 Comparison of the Effects of Rod Types of Rigid Fixation Devices on the Loads in the Lumbar Spine: A Finite Element Analysis
Authors: Bokku Kang, Changsoo Chon, Han Sung Kim
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We developed new design of rod of pedicle screw system that is beneficial in maintaining the spacing between the vertebrae and assessed the performance of the posterior fixation screw systems by numerical analysis according to the range of motion (flexion, extension, lateral bending, and axial rotation) of the vertebral column after inserting the pedicle screws. The simulation results showed that the conventional rod was the most low equivalent stress value among implant units in the case of flexion, extension and lateral bending of the vertebrae. In all cases except the torsional rotation, the results showed that the stress level of the single and double rounded rod exceeded about 30% to 70% compare to the conventional rod. Therefore, this product is not suitable for actual application in the field yet and it seems that product design optimization is necessary. Acknowledgement: This research was supported by the Ministry of Trade, Industry & Energy (MOTIE), Korea Institute for Advancement of Technology (KIAT) through the Encouragement Program for The Industries of Economic Cooperation Region.Keywords: lumber spine, internal fixation device, finite element method, biomechanics
Procedia PDF Downloads 370393 Agricultural Biotechnology Crop Improvement
Authors: Mohsen Rezaei Aghdam
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Recombinant DNA technology has meaningfully augmented the conventional crop improvement and has a great possibility to contribution plant breeders to encounter the augmented food request foretold for the 21st century. Predictable changes in weather and its erraticism, chiefly extreme fevers and vicissitudes in rainfall are expected to brand crop upgrading even more vital for food manufacture. Tissue attitude has been downtrodden to create genetic erraticism from which harvest plants can be better, to improve the state of health of the recognized physical and to upsurge the number of wanted germplasms obtainable to the plant breeder. This appraisal delivers an impression of the chances obtainable by the integration of vegetable biotechnology into plant development efforts and increases some of the social subjects that need to be considered in their application. Public-private companies offer chances to catalyze new approaches and investment while accelerating integrated research and development and commercial supply chain-based solutions. Novel varieties derivative by encouraged mutatgenesis are used commonly: rice in Thailand. These paper combinations obtainable data about the influence of change breeding-derived crop changes around the world, traveler magnetism the possibility of mutation upbringing as a flexible and feasible approach appropriate to any crop if that suitable objectives and selection approaches are used.Keywords: crop, improve, genetic, agricultural
Procedia PDF Downloads 154392 Co-Registered Identification and Treatment of Skin Tumor with Optical Coherence Tomography-Guided Laser Therapy
Authors: Bo-Huei Huang, Chih-Hsun Yang, Meng-Tsan Tsai
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Optical coherence tomography (OCT) enables to provide advantages of noninvasive imaging, high resolution, and high imaging speed. In this study, we integrated OCT and a CW laser for tumor diagnosis and treatment. The axial and transverse resolutions of the developed OCT system are 3 μm and 1 μm, respectively. The frame rate of OCT system is 30 frames/s. In this study, the tumor cells were implanted into the mice skin and scanned by OCT to observe the morphological and angiographic changes. With OCT imaging, 3D microstructures and skin angiography of mice skin can be simultaneously acquired, which can be utilized for identification of the tumor distribution. Then, the CW laser beam can be accurately controlled to expose on the center of the tumor, according to the OCT results. Moreover, OCT was used to monitor the induced photothermolysis and to evaluate the treatment outcome. The results showed that OCT-guided laser therapy could efficiently improve the treatment outcome and the extra damage induced by CW can be greatly reduced. Such OCT-guided laser therapy system could be a potential tool for dermatological applications.Keywords: optical coherence tomography, laser therapy, skin tumor, position guide
Procedia PDF Downloads 271391 The Study of Natural Synthetic Linalool Isolated from Ginger (Zingiber officinale) Using Photochemical Reactions
Authors: Elgendy M. Eman, Sameeh Y. Manal
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Ginger (Zingiber officinale) is so important plant for its medicinal properties from ancient time and used as a spicy herb all over the world. This study was designed to examine the chemical composition of the essential oil and various crude extracts (n-hexane, chloroform and ethanol) of Zingiber officinale as well. GC–MS analyses of the essential oil resulted in the identification of 68 compounds,; 1,8-cineole (8.9%) and linalool (15.1%) were the main components in the essential oil .The crude extracts were analyzed with TLC plates and revealed several spots under UV light; however the hexane extract exhibited the highest number of spots compared to the other extracts. Hexane extract was selected for GC-MS profile, and the results revealed the presence of several volatile compounds and linalool was the major component with high percentage (11.4 %). Further investigation on the structure elucidation of the bioactive compound (linalool) using IR, GC-MS and NMR techniques compared to authenticated linalool then subjected to purification using preparative and column chromatography. Linalool has been epoxidized using m-chloroperbenzoicacid (mcpba) at room temperature in the presence of florescent lamps to give two cyclic oxygenated products (furan epoxide & pyran epoxide) as a stereospecific product.it is concluded that, oxidation process is enhanced by irradiation to form epoxide derivative, which acts as the precursor of important products.Keywords: epoxide, ginger, irradiation, linalool
Procedia PDF Downloads 292390 Complex Cooling Approach in Microchannel Heat Exchangers Using Solid and Hollow Fins
Authors: Nahum Yustus Godi
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A three-dimensional numerical optimisation of combined microchannels with constructal solid, half hollow, and hollow circular fins is documented in this paper. The technique seeks to minimize peak temperature in the entire volume of the microchannel heat sink. The volume and axial length were all fixed, while the width of the microchannel could morph. High-density heat flux was applied at the bottom wall of the microchannel. The coolant employed to remove the heat deposited at the bottom surface of the microchannel was a single-phase fluid (water) in a forced convection laminar condition, and heat transfer was a conjugate problem. The unit cell symmetrical computation domain was discretised, and governing equations were solved using computational fluid dynamic (CFD) code. The results reveal that the combined microchannel with hollow circular fins and solid fins performed better at different Reynolds numbers. The numerical study was validated for the single microchannel without fins and found to be in good agreement with previous studies.Keywords: constructal fins, complex heat exchangers, cooling technique, numerical optimisation
Procedia PDF Downloads 213