Search results for: R. Berglund
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 3

Search results for: R. Berglund

3 DNA Methylation Changes Caused by Lawsone

Authors: Zuzana Poborilova, Anna B. Ohlsson, Torkel Berglund, Anna Vildova, Petr Babula

Abstract:

Lawsone is a pigment that occurs naturally in plants. It has been used as a skin and hair dye for a long time. Moreover, its different biological activities have been reported. The present study focused on the effect of lawsone on a plant cell model represented by tobacco BY-2 cell suspension culture, which is used as a model comparable with the HeLa cells. It has been shown that lawsone inhibits the cell growth in the concentration-dependent manner. In addition, changes in DNA methylation level have been determined. We observed decreasing level of DNA methylation in the presence of increasing concentrations of lawsone. These results were accompanied with overproduction of reactive oxygen species (ROS). Since epigenetic modifications can be caused by different stress factors, there could be a connection between the changes in the level of DNA methylation and ROS production caused by lawsone.

Keywords: DNA methylation, Lawsone, Naphthoquinone, Reactive Oxygen Species.

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2 The Effect of Interlamellar Distance in Pearlite on CGI Machining

Authors: Anders Berglund, Cornel Mihai Nicolescu, Henrik Svensson

Abstract:

Swedish truck industry is investigating the possibility for implementing the use of Compacted Graphite Iron (CGI) in their heavy duty diesel engines. Compared to the alloyed gray iron used today, CGI has superior mechanical properties but not as good machinability. Another issue that needs to be addressed when implementing CGI is the inhomogeneous microstructure when the cast component has different section thicknesses, as in cylinder blocks. Thinner sections results in finer pearlite, in the material, with higher strength. Therefore an investigation on its influence on machinability was needed. This paper focuses on the effect that interlamellar distance in pearlite has on CGI machinability and material physical properties. The effect of pearlite content and nodularity is also examined. The results showed that interlamellar distance in pearlite did not have as large effect on the material physical properties or machinability as pearlite content. The paper also shows the difficulties of obtaining a homogeneous microstructure in inhomogeneous workpieces.

Keywords: Compacted graphite iron (CGI), machinability, microstructure, milling, interlamellar distance in pearlite.

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1 Critical Psychosocial Risk Treatment for Engineers and Technicians

Authors: R. Berglund, T. Backström, M. Bellgran

Abstract:

This study explores how management addresses psychosocial risks in seven teams of engineers and technicians in the midst of the fourth industrial revolution. The sample is from an ongoing quasi-experiment about psychosocial risk management in a manufacturing company in Sweden. Each of the seven teams belongs to one of two clusters: a positive cluster or a negative cluster. The positive cluster reports a significantly positive change in psychosocial risk levels between two time-points and the negative cluster reports a significantly negative change. The data are collected using semi-structured interviews. The results of the computer aided thematic analysis show that there are more differences than similarities when comparing the risk treatment actions taken between the two clusters. Findings show that the managers in the positive cluster use more enabling actions that foster and support formal and informal relationship building. In contrast, managers that use less enabling actions hinder the development of positive group processes and contribute negative changes in psychosocial risk levels. This exploratory study sheds some light on how management can influence significant positive and negative changes in psychosocial risk levels during a risk management process.

Keywords: Group process model, risk treatment, risk management, psychosocial.

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