Search results for: Pargol Ghavam Mostafavi

Authors: Sharareh Sharifi, Pargol Ghavam Mostafavi, Ali Mashinchian Moradi, Mohammad Hadi Givianrad, Hassan Niknejad

Abstract:

Marine organisms such as soft coral, sponge, ascidians, and tunicate containing rich source of natural compound have been studied in last decades because of their special chemical compounds with anticancer properties. The aim of this study was to investigate anti-cancer property of ethyl acetate extracted from marine sea pen Virgularia gustaviana found from Persian Gulf coastal (Bandar Abbas). The extraction processes were carried out with ethyl acetate for five days. Thin layer chromatography (TLC) and high-performance liquid chromatography (HPLC) were used for qualitative identification of crude extract. The viability of HeLa and MDA-Mb-231 cancer cells was investigated using MTT assay at the concentration of 25, 50, and a 100 µl/ml of ethyl acetate is extracted. The crude extract of Virgularia gustaviana demonstrated ten fractions with different Retention factor (Rf) by TLC and Retention time (Rt) evaluated by HPLC. The crude extract dose-dependently decreased cancer cell viability compared to control group. According to the results, the ethyl acetate extracted from Virgularia gustaviana inhibits the growth of cancer cells, an effect which needs to be further investigated in the future studies.

Keywords: Virgularia gustaviana, Cembrane Diterpene, anti-cancer, HeLa cancer Cell, MDA-Md-231 Cancer cell.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1548

Authors: Sandra Ghavam Shirazi, Komeil Valipourian, Mohammad Reza Golhashem

Abstract:

This paper represents the basic idea and mechanisms associated with the durability of geomembranes and discusses the factors influencing the service life and temperature of geomembrane liners. Geomembrane durability is stated as field performance and laboratory test outcomes under various conditions. Due to the high demand of geomembranes as landfill barriers and their crucial role in sensitive projects, sufficient service life of geomembranes is very important, therefore in this paper, the durability, the effect of temperature on geomembrane and the role of this type of reinforcement in different types of soil will be discussed. Also, the role of geomembrane in the earthquake will be considered in the last part of the paper.

Keywords: Geomembrane, durability temperature soil mechanic.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 931

Authors: A. Golshanraz, L. Hakemi, L. Pourkazemi, E. Dadgostar, F. Moradzandi, R. Tabatabaee, F. Moradi, K. Hosseinihajiagha, N. Jazayeri, H. Abedifar, R. Fouladi, M. Khooban, H. Saboori, M. Kiani, M. Sajedi, E. Karooninejad, S.Moeen, M.Ghavam, F.Beiranvand, S.Mansoori, F.Gheisari, H.Barzegari

Abstract:

Supplement use is common in athletes. Besides their cost, they may have side effects on health and performance. 250 questionnaires were distributed among female athletes (mean age 27.08 years). The questionnaire aimed to explore the frequency, type, believes, attitudes and knowledge regarding dietary supplements. Knowledge was good in 30.3%, fair in 60.2%, and poor in 9.1% of respondents. 65.3% of athletes did not use supplements regularly. The most widely used supplements were vitamins (48.4%), minerals (42.9%), energy supplements (21.3%), and herbals (20.9%). 68.9% of athletes believed in their efficacy. 34.4% experienced performance enhancement and 6.8% of reported side effects. 68.2% reported little knowledge and 60.9% were eager to learn more. In conclusion, many of the female athletes believe in the efficacy of supplements and think they are an unavoidable part of competitive sports. However, their information is not sufficient. We have to stress on education, consulting sessions, and rational prescription.

Keywords: athlete, female, sports, supplement

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1744

Authors: Sh. Derakhshan, A. Mostafavi

Abstract:

Nowadays, the challenge in hydraulic turbine design is the multi-objective design of turbine runner to reach higher efficiency. The hydraulic performance of a turbine is strictly depends on runner blades shape. The present paper focuses on the application of the multi-objective optimization algorithm to the design of a small Francis turbine runner. The optimization exercise focuses on the efficiency improvement at the best efficiency operating point (BEP) of the GAMM Francis turbine. A global optimization method based on artificial neural networks (ANN) and genetic algorithms (GA) coupled by 3D Navier-Stokes flow solver has been used to improve the performance of an initial geometry of a Francis runner. The results show the good ability of optimization algorithm and the final geometry has better efficiency with initial geometry. The goal was to optimize the geometry of the blades of GAMM turbine runner which leads to maximum total efficiency by changing the design parameters of camber line in at least 5 sections of a blade. The efficiency of the optimized geometry is improved from 90.7% to 92.5%. Finally, design parameters and the way of selection have been considered and discussed.

Keywords: Francis Turbine, Runner, Optimization, CFD

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3341

Authors: Mahkameh S. Mostafavi

Abstract:

In this paper an algorithm is used to detect the color defects of ceramic tiles. First the image of a normal tile is clustered using GCMA; Genetic C-means Clustering Algorithm; those results in best cluster centers. C-means is a common clustering algorithm which optimizes an objective function, based on a measure between data points and the cluster centers in the data space. Here the objective function describes the mean square error. After finding the best centers, each pixel of the image is assigned to the cluster with closest cluster center. Then, the maximum errors of clusters are computed. For each cluster, max error is the maximum distance between its center and all the pixels which belong to it. After computing errors all the pixels of defected tile image are clustered based on the centers obtained from normal tile image in previous stage. Pixels which their distance from their cluster center is more than the maximum error of that cluster are considered as defected pixels.

Keywords: C-Means algorithm, color spaces, Genetic Algorithm, image clustering.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1649

Authors: A. Ghaffari, A. S. Mostafavi

Abstract:

Complex assemblies of interacting proteins carry out most of the interesting jobs in a cell, such as metabolism, DNA synthesis, mitosis and cell division. These physiological properties play out as a subtle molecular dance, choreographed by underlying regulatory networks that control the activities of cyclin-dependent kinases (CDK). The network can be modeled by a set of nonlinear differential equations and its behavior predicted by numerical simulation. In this paper, an innovative approach has been proposed that uses genetic algorithms to mine a set of behavior data output by a biological system in order to determine the kinetic parameters of the system. In our approach, the machine learning method is integrated with the framework of existent biological information in a wiring diagram so that its findings are expressed in a form of system dynamic behavior. By numerical simulations it has been illustrated that the model is consistent with experiments and successfully shown that such application of genetic algorithms will highly improve the performance of mathematical model of the cell division cycle to simulate such a complicated bio-system.

Keywords: Cell cycle, Cyclin-dependent kinase, Fission yeast, Genetic algorithms, Mathematical modeling, Wiring diagram

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1505

Authors: Khodadad Mostafavi, Alireza Nabipour, Mohammad Norouzi

Abstract:

Biplot can be used to evaluate cultivars for their oil percent potential and stability and to evaluate trial sites for their discriminating ability and representativeness. Multi-environmental trial (MET) data for oil percent of 10 open pollinating sunflower cultivars were analyzed to investigate the genotype-environment interactions. The genotypes were evaluated in four locations with different climatic conditions in Iran in 2010. In each location, a Randomized Complete Block design with four replications was used. According to both mean and stability, Zaria, Master and R453, had highest performances among all cultivars. The graphical analysis identified best cultivar for each environment. Cultivars Berezans and Record performed best in Khoy and Islamabad. Zaria and R453 were the best genotypes in Sari and Karaj followed by Master and Favorit. The GGE bi-plot indicated two mega-environments, group one contained Karaj, Khoy and Islamabad and the second group contained Sari. The best discriminating location was Karaj followed with Khoy, Islamabad and Sari. The best representative genotypes were Zaria, R453, Master and Favorit. Ranking of ten cultivars based their oil percent was as Zaria > R453 ≈ Master ≈ Favorit > Record ≈ Berezans > Sor > Lakumka > Bulg3 > Bulg5.

Keywords: Stability, Bi-plot, Genotype- environment interaction, Sunflower

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1394

Authors: Mozhgan Ziaie Bidhendi, Rajab Choukan, Farokh Darvish, Khodadad Mostafavi, Eslam Majidi

Abstract:

The selection of parents and breeding strategies for the successful maize hybrid production will be facilitated by heterotic groupings of parental lines and determination of combining abilities of them. Fourteen maize inbred lines, used in maize breeding programs in Iran, were crossed in a diallel mating design. The 91 F1 hybrids and the 14 parental lines were studied during two years at four locations of Iran for investigation of combining ability of gentypes for grain yield and to determine heterotic patterns among germplasm sources, using both, the Griffing-s method and the biplot approach for diallel analysis. The graphical representation offered by biplot analysis allowed a rapid and effective overview of general combining ability (GCA) and specific combining ability (SCA) effects of the inbred lines, their performance in crosses, as well as grouping patterns of similar genotypes. GCA and SCA effects were significant for grain yield (GY). Based on significant positive GCA effects, the lines derived from LSC could be used as parent in crosses to increase GY. The maximum best- parent heterosis values and highest SCA effects resulted from crosses B73 × MO17 and A679 × MO17 for GY. The best heterotic patterns were LSC × RYD, which would be potentially useful in maize breeding programs to obtain high-yielding hybrids in the same climate of Iran.

Keywords: biplot, diallel, Griffing, Heterotic pattern

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 5619