Search results for: biomicroscope

Authors: Xiwei Huang, Hyouk-Kyu Cha, Dongning Zhao, Bin Guo, Minkyu Je, Hao Yu

Abstract:

This paper presents the design and implementation of a fully integrated transimpedance amplifier (TIA) as the analog frontend receiver for Capacitive Micromachined Ultrasound Transducers (CMUTs) for ultrasound biomicroscope imaging application. The amplifier is designed to amplify the received signals from 17.5MHz to 52.5MHz with a center frequency of 35MHz. The TIA was fabricated in GF 0.18μm 1P6M 30V high voltage process. The measurement results show that the designed amplifier can reach a transimpedance gain of 61.08dBΩ and operating frequency from 17.5MHz to 100MHz with 1VP-P output voltage under 6V power supply.

Keywords: 3D ultrasound biomicroscope, analog front-end, transimpedance amplifier, CMUT

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Authors: Bashirah Ishak, Jacyln JiaYing Thye, Bariah Mohd Ali, Norhani Mohidin

Abstract:

Background Contact lens (CL) wear can cause changes in blinking and corneal staining. Aims and Objectives To determine the effects of CL materials (HEMA and SiHy) on spontaneous blink rate, blinking patterns and corneal staining after 2 months of wear. Methods Ninety subjects in 3 groups (control, HEMA and SiHy) were assessed at baseline and 2-months. Blink rate was recorded using a video camera. Blinking patterns were assessed with digital camera and slit lamp biomicroscope. Corneal staining was graded using IER grading scale Results There were no significant differences in all parameters at baseline. At 2 months, CL wearers showed significant increment in average blink rate (F1.626, 47.141 = 7.250, p = 0.003; F2,58 = 6.240, p = 0.004) and corneal staining (χ2 2, n=30 = 31.921, p < 0.001; χ2 2, n=30 = 26.909, p < 0.001). Conclusion Blinking characteristics and corneal staining were not influence by soft CL materials.

Keywords: Spontaneous blinking, cornea staining, grading, soft contact lenses.

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Authors: Haridas Kuruveettil, Dongning Zhao, Cheong Jia Hao, Minkyu Je

Abstract:

We present the design of Analog front end (AFE) low noise pre-amplifier implemented in a high voltage 0.18-µm CMOS technology for  a three dimensional ultrasound  bio microscope (3D UBM) application. The fabricated chip has 4X16 pre-amplifiers implemented to interface   a 2-D array of    high frequency capacitive micro-machined ultrasound transducers (CMUT). Core AFE cell consists of a high-voltage pulser in the transmit path, and a low-noise transimpedance amplifier in the receive path. Proposed system offers a high image resolution by the use of high frequency CMUTs with associated high performance imaging electronics integrated together.  Performance requirements and the design methods of the high bandwidth transimpedance amplifier are described in the paper. A single cell of transimpedance (TIA) amplifier and the bias circuit occupies a silicon area of 250X380 µm² and the full chip occupies a total silicon area of 10x6.8 mm².

Keywords: Ultrasound, analog front end, medical imaging, beam forming, biomicroscope, transimpedance gain.

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