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Performance Evaluation of Complex Electrical Bio-impedance from V/I Four-electrode Measurements

Authors: Salim Istyaq, Towfeeq Fairooz


The passive electrical properties of a tissue depends on the intrinsic constituents and its structure, therefore by measuring the complex electrical impedance of the tissue it might be possible to obtain indicators of the tissue state or physiological activity [1]. Complete bio-impedance information relative to physiology and pathology of a human body and functional states of the body tissue or organs can be extracted by using a technique containing a fourelectrode measurement setup. This work presents the estimation measurement setup based on the four-electrode technique. First, the complex impedance is estimated by three different estimation techniques: Fourier, Sine Correlation and Digital De-convolution and then estimation errors for the magnitude, phase, reactance and resistance are calculated and analyzed for different levels of disturbances in the observations. The absolute values of relative errors are plotted and the graphical performance of each technique is compared.

Keywords: fast fourier transform, Additive White Gaussian Noise, Electrical Impedance, Total Least Square, Digital De-Convolution, Sine-Correlation

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[1] "Development of Electrical Bioimpedance Technology in Future" Proceedings of the 20th Annual Conference of the IEEE Engineering in Medicine and Biology Society, Vol 20, No 2, 1998.
[2] Sverre Grimnes, Orjan Grottem Martinsen 2000 Bioimpedance and Bioelectricity Basics (San Diego, CA: Academic)
[3] "Thoracic Electrical Bioimpedance in the Outpatient Setting" Policy#:MED.00034. Medical Policy. Available: .html
[4] Jaakko Malmivuo & Robert Plonsey, Bioelectromagnetism - Principles and Applications of Bioelectric and Biomagnetic Fields, Oxford University Press, New York, 1995. Available:
[5] Herman P.Schwan and Kenneth R. Foster "Departmental Papers (BE)"Department of Bioengineering, University of Pennsylvania, Year 2002.
[6] Sverre Grimnes, Orjan Grottem Martinsen" Bioimpedance--. University of Oslo, Oslo, Norway. Available:
[7] Y.Komai, E.yasuno, Y.Kinouchi.K.Izukura, T.Iritani, T.Morinoto and M.Takeuchi "Estimation of Bioimpedance Distribution in the Local Tissue Using Divided Electrodes". Seventh International Conference on Control, Automation, Robotics and Vision (ICARV-02), Dec 2002, Singapore. Available: r=1234941&isnumber=27684
[8] Paul Steendijk, Gerrit Mur, Enno T, Van Der Velde, and Jan Baan "The Four -Electrode Resistivity technique in Anisotropic Media: Theoretical Analysis and Application on Myocardial Tissue in Vivo". IEEE Transactions on Biomedical Engineering, Vol. 40, NO 11, November 1993. Available: 45632&isnumber=6298
[9] J.J.Ackmann and A S Seitz, ÔÇÿ-Methods of complex impedance measurements in biological tissue,-- CRC Crit Rev. Biom. Eng., vol. 10, pp. 281-311, 1984.
[10] H.P.Schwan, ÔÇÿ-Determination of biological impedances,-- in Nastuk, Ed. Physical Techniques in Biological Research, New York, Academic, 1963.
[11] Sverre Grimnes et al 2007 ÔÇÿ- Sources of error in tetrapolar impedance measurements on biomaterials and other ionic conductors-- J.Phys. D: Appl. Phys. 40 9-14 doi: 10.1088/0022-3727/40/1/S02. Available:
[12] MD. Anisur Rahman and Kai-Bor Yu, member IEEE ÔÇÿ-Total Least Squares Approach for Frequency Estimation Using Linear Prediction-- IEEE Transactions on Acoustics, Speech and Signal Processing, Vol. ASSP-35, No. 10, October 1987 Available: .