Commenced in January 2007
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Search results for: Volodymyr Chegel
1 Modeling of Sensitivity for SPR Biosensors- New Aspects
Authors: Volodymyr Chegel
Abstract:
The computer modeling is carried out for parameter of sensitivity of optoelectronic chemical and biosensors, using phenomena of surface plasmon resonance (SPR). The physical model of SPR-sensor-s is described with (or without) of modifications of sensitive gold film surface by a dielectric layer. The variants of increasing of sensitivity for SPR-biosensors, constructed on the principle gold – dielectric – biomolecular layer are considered. Two methods of mathematical treatment of SPR-curve are compared – traditional, with estimation of sensor-s response as shift of the SPRcurve minimum and proposed, for system with dielectric layer, using calculating of the derivative in the point of SPR-curve half-width.Keywords: Surface Plasmon Resonance, modeling, sensitivity, biosensor
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