Search results for: Liu Yuxin

2 Case Studies of CSAMT Method Applied to Study of Complex Rock Mass Structure and Hidden Tectonic

Authors: Yuxin Chen, Qingyun Di, C. Dinis da Gama

Abstract:

In projects like waterpower, transportation and mining, etc., proving up the rock-mass structure and hidden tectonic to estimate the geological body-s activity is very important. Integrating the seismic results, drilling and trenching data, CSAMT method was carried out at a planning dame site in southwest China to evaluate the stability of a deformation. 2D and imitated 3D inversion resistivity results of CSAMT method were analyzed. The results indicated that CSAMT was an effective method for defining an outline of deformation body to several hundred meters deep; the Lung Pan Deformation was stable in natural conditions; but uncertain after the future reservoir was impounded. This research presents a good case study of the fine surveying and research on complex geological structure and hidden tectonic in engineering project.

Keywords: CSAMT Surveying, Deformation Stability.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2395

1 Optimization of Breast Tumor Cells Isolation Efficiency and Purity by Membrane Filtration

Authors: Bhuvanendran Nair Gourikutty Sajay, Liu Yuxin, Chang Chia-Pin, Poenar Daniel Puiu, Abdur Rub Abdur Rahman

Abstract:

Size based filtration is one of the common methods employed to isolate circulating tumor cells (CTCs) from whole blood. It is well known that this method suffers from isolation efficiency to purity tradeoff. However, this tradeoff is poorly understood. In this paper, we present the design and manufacturing of a special rectangular slit filter. The filter was designed to retain maximal amounts of nucleated cells, while minimizing the pressure on cells, thereby preserving their morphology. The key parameter, namely, input pressure, was optimized to retain the maximal number of tumor cells, whilst maximizing the depletion of normal blood cells (red and white blood cells and platelets). Our results indicate that for a slit geometry of 5 × 40 μm on a 13 mm circular membrane with a fill factor of 21%, a pressure of 6.9 mBar yields the optimum for maximizing isolation of MCF-7 and depletion of normal blood cells.

Keywords: Circulating tumor cells, Parylene slit membrane, Retention, White Blood Cell depletion.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1792