Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 30054
Feasibility of Leukemia Cancer Treatment (K562) by Atmospheric Pressure Plasma Jet

Authors: Mashayekh Amir Shahriar, Akhlaghi Morteza, Rajaee Hajar, Khani Mohammad Reza, Shokri Babak

Abstract:

A new and novel approach in medicine is the use of cold plasma for various applications such as sterilization blood coagulation and cancer cell treatment. In this paper a pin-to-hole plasma jet suitable for biological applications is investigated and characterized and the possibility and feasibility of cancer cell treatment is evaluated. The characterization includes power consumption via Lissajous method, thermal behavior of plasma using Infra-red camera as a novel method, Optical Emission Spectroscopy (OES) to determine the species that are generated. Treatment of leukemia cancer cells is also implemented and MTT assay is used to evaluate viability.

Keywords: Atmospheric Pressure Plasma Jet (APPJ), Plasma Medicine, Cancer cell treatment, leukemia.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1096561

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF

References:


[1] Y.Akishev, M. Grushin, A. Napartovich, and N. Turshkin,”Novel ac and dc non-thermal plasma source for cold surface treatment of polymer films and fabrics at atmospheric pressure,” Plasmas Polym., vol7, no.3, pp. 261-289, sep 2002.W.-K. Chen, Linear Networks and Systems (Book style). Belmont, CA: Wadsworth, 1993, pp. 123–135.
[2] T.I.Lee, K. W.Park, H. K. Baik, and S.-M. Lee “Dielectric Barrier Hollow cathode discharge snd its enhanced performance for light source,” Appl. Phys. Lett., vol 87, no. 26, pp. 261 502-1-261 502-3, Dec. 26, 2005.
[3] G. Fridman, G. Friedman, A. Gustol, A. B. Shekhter, V. N. Vasilets, and A. Fridman, “Applied plasma medicine,” Plasma Process. Polym., vol. 5, no. 6, pp. 503-533, Aug. 2008.
[4] R. M. Sankaran and K. P. Giapis, “Maskless etching of silicon using patterned microdischarges,” Appl. Phys. Lett., vol. 79, no. 5, pp. 593- 595. Jul.30, 2001.
[5] M. Thiyagarajan, A. Sarani, X. Gonzales, “Characterization of Portable Resistive Barrier Plasma Jet and Its Direct and Indirect Treatment for Antibiotic Resistant Bacteria and THP-1 Luekemia Cancer cells” IEEE Transaction on Plasma Science, vol. 40, no. 12, December 2012.
[6] Ulrich Kogelschatz; “Dielectric-barrier Discharges: Their History, Discharge Physics, and Industrial Applications”; Plasma Chemistry and Plasma Processing, 23, No.1, (2003)..
[7] Ehlbeck J, Schnbel U, Polak M, Winter J, Von Woedtke T, Brandenburg R, von dem Hagen T and Weltmann K 2011 J.Phys. D: Appl. Phys. 44 013002M. Young, TheTechincal Writers Handbook.Mill Valley, CA: University Science, 1989.
[8] Fridman G, Shereshevsky A, Jost M M, Brooks A D, Fridman A, Gutsol A, Vasilets V and Friedman G 2007 Plasma Chem. Plasma Process S. Chen, B. Mulgrew, and P. M. Grant, “A clustering technique for digital communications channel equalization using radial basis function networks,” IEEE Trans. Neural Networks, vol. 4, pp. 570–578, July 1993.
[9] Kalghatgi S U, Fridman G, Cooper M, Nagaraj G, Peddinghaus M, Balasubramanian M, Vasilets V N, Gutsol A F, Fridman A and Friedman G 2007; IEEE Trans. Plasma Sci 115016S. P. Bingulac, “On the compatibility of adaptive controllers (Published Conference Proceedings style),” in Proc. 4th Annu. Allerton Conf. Circuits and Systems Theory, New York, 1994, pp. 8–16.
[10] Lloyd G, Friedman G, Jafri S, Schultz G, Fridman A and Harding K; Plasma Process. Polym. (2010)
[11] Sun P, Pan J, Tian Y, Bai N, Wu H, Wang L, Yu C, Zhang J, Zhu W and Beckerr K H; IEEE Trans. Plasma Sci, (2010).
[12] E. Stoffels, I. E. Keift, R. E. J. Sladek, L. J. M. van den Bedem, E. P. vander Laan, and M. Steinbuch, “Plasma needle for in vivo medical treatment: Recent developments and perspectives,”Plasma Sources Sci. Technol. 15, S169-S180 (2006).