{"title":"Feasibility of Leukemia Cancer Treatment (K562) by Atmospheric Pressure Plasma Jet","authors":"Mashayekh Amir Shahriar, Akhlaghi Morteza, Rajaee Hajar, Khani Mohammad Reza, Shokri Babak","volume":94,"journal":"International Journal of Physical and Mathematical Sciences","pagesStart":723,"pagesEnd":727,"ISSN":"1307-6892","URL":"https:\/\/publications.waset.org\/pdf\/9999593","abstract":"
A new and novel approach in medicine is the use of
\r\ncold plasma for various applications such as sterilization blood
\r\ncoagulation and cancer cell treatment. In this paper a pin-to-hole
\r\nplasma jet suitable for biological applications is investigated and
\r\ncharacterized and the possibility and feasibility of cancer cell
\r\ntreatment is evaluated. The characterization includes power
\r\nconsumption via Lissajous method, thermal behavior of plasma using
\r\nInfra-red camera as a novel method, Optical Emission Spectroscopy
\r\n(OES) to determine the species that are generated. Treatment of
\r\nleukemia cancer cells is also implemented and MTT assay is used to
\r\nevaluate viability.<\/p>\r\n","references":"[1] Y.Akishev, M. Grushin, A. Napartovich, and N. Turshkin,\u201dNovel ac and\r\ndc non-thermal plasma source for cold surface treatment of polymer\r\nfilms and fabrics at atmospheric pressure,\u201d Plasmas Polym., vol7, no.3,\r\npp. 261-289, sep 2002.W.-K. Chen, Linear Networks and Systems (Book\r\nstyle). Belmont, CA: Wadsworth, 1993, pp. 123\u2013135.\r\n[2] T.I.Lee, K. W.Park, H. K. Baik, and S.-M. Lee \u201cDielectric Barrier\r\nHollow cathode discharge snd its enhanced performance for light\r\nsource,\u201d Appl. Phys. Lett., vol 87, no. 26, pp. 261 502-1-261 502-3, Dec.\r\n26, 2005.\r\n[3] G. Fridman, G. Friedman, A. Gustol, A. B. Shekhter, V. N. Vasilets, and\r\nA. Fridman, \u201cApplied plasma medicine,\u201d Plasma Process. Polym., vol.\r\n5, no. 6, pp. 503-533, Aug. 2008.\r\n[4] R. M. Sankaran and K. P. Giapis, \u201cMaskless etching of silicon using\r\npatterned microdischarges,\u201d Appl. Phys. Lett., vol. 79, no. 5, pp. 593-\r\n595. Jul.30, 2001.\r\n[5] M. Thiyagarajan, A. Sarani, X. Gonzales, \u201cCharacterization of Portable\r\nResistive Barrier Plasma Jet and Its Direct and Indirect Treatment for\r\nAntibiotic Resistant Bacteria and THP-1 Luekemia Cancer cells\u201d IEEE\r\nTransaction on Plasma Science, vol. 40, no. 12, December 2012.\r\n[6] Ulrich Kogelschatz; \u201cDielectric-barrier Discharges: Their History,\r\nDischarge Physics, and Industrial Applications\u201d; Plasma Chemistry and\r\nPlasma Processing, 23, No.1, (2003)..\r\n[7] Ehlbeck J, Schnbel U, Polak M, Winter J, Von Woedtke T, Brandenburg\r\nR, von dem Hagen T and Weltmann K 2011 J.Phys. D: Appl. Phys. 44\r\n013002M. Young, TheTechincal Writers Handbook.Mill Valley, CA:\r\nUniversity Science, 1989.\r\n[8] Fridman G, Shereshevsky A, Jost M M, Brooks A D, Fridman A, Gutsol\r\nA, Vasilets V and Friedman G 2007 Plasma Chem. Plasma Process S.\r\nChen, B. Mulgrew, and P. M. Grant, \u201cA clustering technique for digital\r\ncommunications channel equalization using radial basis function\r\nnetworks,\u201d IEEE Trans. Neural Networks, vol. 4, pp. 570\u2013578, July\r\n1993.\r\n[9] Kalghatgi S U, Fridman G, Cooper M, Nagaraj G, Peddinghaus M,\r\nBalasubramanian M, Vasilets V N, Gutsol A F, Fridman A and\r\nFriedman G 2007; IEEE Trans. Plasma Sci 115016S. P. Bingulac, \u201cOn\r\nthe compatibility of adaptive controllers (Published Conference\r\nProceedings style),\u201d in Proc. 4th Annu. Allerton Conf. Circuits and\r\nSystems Theory, New York, 1994, pp. 8\u201316.\r\n[10] Lloyd G, Friedman G, Jafri S, Schultz G, Fridman A and Harding K;\r\nPlasma Process. Polym. (2010)\r\n[11] Sun P, Pan J, Tian Y, Bai N, Wu H, Wang L, Yu C, Zhang J, Zhu W and\r\nBeckerr K H; IEEE Trans. Plasma Sci, (2010).\r\n[12] E. Stoffels, I. E. Keift, R. E. J. Sladek, L. J. M. van den Bedem, E. P.\r\nvander Laan, and M. Steinbuch, \u201cPlasma needle for in vivo medical\r\ntreatment: Recent developments and perspectives,\u201dPlasma Sources Sci.\r\nTechnol. 15, S169-S180 (2006).","publisher":"World Academy of Science, Engineering and Technology","index":"Open Science Index 94, 2014"}