Evolution of Cord Absorbed Dose during of Larynx Cancer Radiotherapy, with 3D Treatment Planning and Tissue Equivalent Phantom

Authors: Mohammad Hassan Heidari, Amir Hossein Goodarzi, Majid Azarniush

Abstract:

Radiation doses to tissues and organs were measured using the anthropomorphic phantom as an equivalent to the human body. When high-energy X-rays are externally applied to treat laryngeal cancer, the absorbed dose at the laryngeal lumen is lower than given dose because of air space, which it should pass through, before reaching the lesion. Specially, in case of high-energy X-rays, the loss of dose is considerable. Three-dimensional absorbed dose distributions have been computed for high-energy photon radiation therapy of laryngeal and hypopharyngeal cancers, using a coaxial pair of opposing lateral beams in fixed positions. Treatment plans obtained under various conditions of irradiation.

Keywords: 3D Treatment Planning, anthropomorphic phantom, larynx cancer, radiotherapy.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1089593

References:

[1] R. Siegel, D. Naishadham, et al. Cancer statistics, 2013. CA Cancer J Clin 2013; 63:11–30.
[2] R, Amornmarn, T. rempree , J. Jaiwatana, et al "Radiation management of carcinoma of the tonsillar region” Cancer 1984;54:1293–1299.
[3] G. H. Fletcher, H. Goepfert "Larynx and pyriform sinus”. In: Fletcher GH, ed. Textbook of Radiotherapy, 3rd ed. Philadelphia: Lea & Febiger; 1980:330–363.
[4] A. R. Harwood, F. A. Beale, B. J. Cummings, et al. "T2 glottic cancer: An analysis of dose-time-volume factors”. Int J Radiat Oncol Biol Phys 1981; 7:1501–1505.
[5] A. R. Harwood, N. V. Hawkins, W. D. Rider, et al. "Radiotherapy of early glottic cancer”. Int J Radiat Oncol Biol Phys 1979;5:473–476.
[6] G. Busuoli. General characteristics of TL materials. In: Oberhofer M, Scharmann A, editors. Applied thermoluminescence dosimetry: lectures of a course held at the Joint Research Centre, Ispra, 12–16 November 1979, 87. Bristol: Adam Hilger Ltd; 1981.
[7] I.C.R.U. Report 50: Prescribing, Recording, and Reporting Photon Beam Therapy. International Commission on Radiation Units and Measurements, Bethesda, Maryland, USA, 1993.
[8] T. Cheung, M. J. Butson, Yu PKM. "Measurement of high energy x-ray beam penumbra with Gafchromic EBT radiochromic film” Med Phys. 2006;33(8):2912-2914.
[9] T. Cheung, M. J. Butson, Yu PKM "Measurement of high energy x-ray beam penumbra with Gafchromic EBT radiochromic film” Med Phys. 2006; 33(8):2912-2914.
[10] M. Todorovic, M. Fischer, F. Cremers, E. Thom, R. Schmidt "Evaluation of GafChromic EBT prototype B for external beam dose verification” Med Phys. 2006;33(5):1321-1328.
[11] M. J. Butson, T. Cheung, Yu PK "Absorption spectra variations of EBT radiochromic film radiation exposure”. Phys Med Biol. 2005; 50(13):N135-N140.