Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 31103
Thermodynamic Study for Aggregation Behavior of Hydrotropic Solution

Authors: Meghal Desai, Jigisha Parikh


Aggregation behavior of sodium salicylate and sodium cumene sulfonate was studied in aqueous solution at different temperature. Specific conductivity and relative viscosity were measured at different temperature to find minimum hydrotropic concentration. The thermodynamic parameters (free energy, enthalpy and entropy) were evaluated in the temperature range of 30°C-70°C. The free energy decreased with increase in temperature. The aggregation was found to be exothermic in nature and favored by positive value of entropy.

Keywords: Entropy, Free Energy, Enthalpy, Hydrotropes, Minimum Hydrotropic Concentration

Digital Object Identifier (DOI):

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1421


[1] Lee, J., Lee, S. C., Acharya, G., Chang, C. and Park, K., "Hydrotropic solubilization of paclitaxel: analysis of chemical structures for hydrotropic property," Pharm. Res., vol. 20, no. 7, pp. 1022-1030, 2003.
[2] B. M. Khadilkar, V. G. Gaikar and A. A. Chitnavis, "HAqueous hydrotrope solution as a safer medium for microwave enhanced hantzsch dihydropyridine ester synthesis,"H Tetrahedron Lett., vol. 36, no. 44, pp. 8083-8086, 1995.
[3] V. G. Gaikar and P. V. Phatak, "Selective solubilization of isomers in hydrotrope solutions: o-/p-chlorobenzoic acids and o-/pnitroanilines," Sep. Sci. Technol., vol. 34, no. 3, pp. 439-459, 1999.
[4] D. V. Dandekar and V. G. Gaikar, "Hydrotropic extraction of curcuminoids from turmeric," Sep. Sci. Technol., vol. 38, no. 5, pp. 1185-1215, 2003.
[5] G. Raman and V. G. Gaikar, "Extraction of piperine from Piper nigrum (black pepper) by hydrotropic solubilization," Ind. Eng. Chem. Res., vol. 41, no. 12, pp. 2966-2976, 2002.
[6] G. Raman and V. G. Gaikar, "HHydrotropic solubilization of boswellic acids from boswellia serrata resinH," Langmuir, vol. 19, no. 19, pp. 8026-8032, 2003.
[7] M. Bhat and V. G. Gaikar, "HCharacterization of interaction between butylbenzene sulfonates and cetyl pyridinium chloride in a mixed aggregate systemH," Langmuir, vol. 16, no. 4, pp. 1580-1592, 2000.
[8] M. Bhat and V. G. Gaikar, "HCharacterization of interaction between butyl benzene sulfonates and cetyl trimethylammonium bromide in mixed aggregate systemsH," Langmuir, vol. 15, no. 14, pp. 4740-4751, 1999.
[9] V. G. Gaikar and M. M. Sharma, "Separations with hydrotropes," Sep. Technol., vol. 3, no. 1, pp. 2-11, 1993.
[10] G. Perron and J. E. Desnoyers, "Volumes and heat capacities of sodium perfluoroalkanoates in water," J. Chem. Eng. Data, vol. 42, no. 1, pp. 172-178, 1997.
[11] F. Quiron and J. E. Desnoyers, "HA thermodynamic study of the postmicellar transition of cetyltrimethylammonium bromide in waterH," J. Colloid Interface Sci., vol. 112, no. 2, pp. 565-572, 1986.
[12] D. Balasubramanian, V. Srinivas, V. G. Gaikar and M. M. Sharma, "Aggregation behavior of hydrotropic compounds in aqueous solution," J. Phys. Chem., vol. 93, no. 9, pp. 3865-3870, 1989.
[13] P. Bahadur, J. Parikh and D. Varade, "Adsorption characteristics and micelle formation of two cationic surfactants and their mixtures in aqueous solution," Tenside Surf. Det., vol. 40, no. 4, pp. 215-219, 2003.
[14] V. B. Wagle, P. S. Kothari and V. G. Gaikar, "Effect of temperature on aggregation behavior of aqueous solutions of sodium cumene sulfonate," J. Mol. Liq., vol. 133, no. 1-3, pp. 68-76, 2007.