Hemodynamic Characteristics in the Human Carotid Artery Model Induced by Blood-Arterial Wall Interactions

Authors: Taewon Seo

Abstract:

The characteristics of physiological blood flow in human carotid arterial bifurcation model have been numerically studied using a fully coupled fluid-structure interaction (FSI) analysis. This computational model with the fluid-structure interaction is constructed to investigate the flow characteristics and wall shear stress in the carotid artery. As the flow begins to decelerate after the peak flow, a large recirculation zone develops at the non-divider wall of both internal carotid artery (ICA) and external carotid artery (ECA) in FSI model due to the elastic energy stored in the expanding compliant wall. The calculated difference in wall shear stress (WSS) in both Non-FSI and FSI models is a range of between 5 and 11% at the mean WSS. The low WSS corresponds to regions of carotid artery that are more susceptible to atherosclerosis.

Keywords: Carotid artery, Fluid-structure interaction, Hemodynamics, Wall shear stress.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1088454

References:

[1] P.J. Blanco, M.R. Pivello, R. A. Feijoo, & S.Urquiza, Sensitivity of blood flow at the carotid artery to the heart inflow boundary condition, 3rd International Congress on Comput. Bioeng., Isla de Maragarita, Venezuela(2007) 1-6.
[2] S.Z. Zhao, X.Y. Xu, A.D. Hughes, S.A. Thom, A.V. Stanton, B. Ariff, & Q. Long, Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation,J. of Biomech, 33 (2000)975-984.
[3] N. A., Buchmann& M.C. Jermy, Blood flow measurements in idealized and patient specific models of the human carotid artery, 14th Int. Symp. On Applications of Laser Techniques to Fluid Mechanics, Lisbon, Portugal (2008) 1-11.
[4] S.W. Lee, L. Antiga, D. Spence & D.A. Steinman, Geometry of the carotid bifurcation predicts its exposure to disturbed flow, Stroke AHAJ, 39 (2008)2341-2347.
[5] E. Shaik, K.A. Hoffmann & J.F. Dietiker, Numerical flow simulations of blood in arteries, 4th AIAA Aerospace Science Meeting and Exhibit, Reno, Nevada, USA (2006)294-307.
[6] D. Tang, J. Yang, C. Yang & D. N. Ku, Experiment – based numerical simulation of unsteady viscous flow in Stenotic Elastic Tubes, J. Biomech. Eng., 121 (2001) 299-320.
[7] B. E. Powell Experimental measurements of Flow through stenotic collapsible tubes, M. S. Thesis, Georgia Inst. of Tech. (1991).
[8] Jr., J. R. Buchanan, C. Kleinstreuer& J. K. Comer, Rheological Effects on Pulsatile Hemodynamic in a Stenosed Tube, Compute. Fluids, 29 (2000) 695–724.
[9] B.Buriev& T.W. Seo, Fluid-Structure Interactions of Physiological Flow in Stenosed Artery, J. Korea-Australia Rheology, 21 (2009) 39-46.
[10] Y. Fan, W. Jiang, Y. Zou, J. Li,J.Chen& X. Deng, Numerical simulation of pulsatile non-Newtonian flow in the carotid artery bifurcation, ActaMech Sin, 25 (2009)249-255.