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Biomechanical Prediction of Veins and Soft Tissues beneath Compression Stockings Using Fluid-Solid Interaction Model

Authors: Chongyang Ye, Rong Liu


Elastic compression stockings (ECSs) have been widely applied in prophylaxis and treatment of chronic venous insufficiency of lower extremities. The medical function of ECS is to improve venous return and increase muscular pumping action to facilitate blood circulation, which is largely determined by the complex interaction between the ECS and lower limb tissues. Understanding the mechanical transmission of ECS along the skin surface, deeper tissues, and vascular system is essential to assess the effectiveness of the ECSs. In this study, a three-dimensional (3D) finite element (FE) model of the leg-ECS system integrated with a 3D fluid-solid interaction (FSI) model of the leg-vein system was constructed to analyze the biomechanical properties of veins and soft tissues under different ECS compression. The Magnetic Resonance Imaging (MRI) of the human leg was divided into three regions, including soft tissues, bones (tibia and fibula) and veins (peroneal vein, great saphenous vein, and small saphenous vein). The ECSs with pressure ranges from 15 to 26 mmHg (Classes I and II) were adopted in the developed FE-FSI model. The soft tissue was assumed as a Neo-Hookean hyperelastic model with the fixed bones, and the ECSs were regarded as an orthotropic elastic shell. The interfacial pressure and stress transmission were simulated by the FE model, and venous hemodynamics properties were simulated by the FSI model. The experimental validation indicated that the simulated interfacial pressure distributions were in accordance with the pressure measurement results. The developed model can be used to predict interfacial pressure, stress transmission, and venous hemodynamics exerted by ECSs and optimize the structure and materials properties of ECSs design, thus improving the efficiency of compression therapy.

Keywords: Elastic compression stockings, fluid-solid interaction, tissue and vein properties, prediction.

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[1] N Jones, R Rees, V Kakkar. A Physiological Study of Elastic Compression Stockings in Venous Disorders of the leg, Br J Surg67: pp. 569-572, 1980.
[2] WRobert, DDavid. Clinical Benefits of Lightweight Compression: Reduction of Venous‐Related Symptoms by Ready‐to‐Wear Lightweight Gradient Compression Hosiery.DermatolSurg,25.9, pp. 701-704. 1999.
[3] Liu R, Guo X, Lao TT, Little TJ. A critical review on compression textiles for compression therapy: Textile-based compression interventions for chronic venous insufficiency. Textile Research Journal, 87(9), pp. 1121-1141, 2017.
[4] JOLaurikka, T Sisto, M RTarkka, O Auvinen, and M Hakama,Risk Indicators for Varicose Veins in Forty-to-sixty-year-olds in the Tampere Varicose Vein Study, World Journal of Surgery, 26(6), pp.648, 2002.
[5] Liu R, Lao TT, Kwok YL, Li Y, Ying M. Effects of Graduated Compression Stockings with Different Pressure Profiles on Lower-limb Venous Structures and Hemodynamics. Advances in Therapy, 25(5), pp. 465-478, 2008.
[6] Liu R, Kwok YL, Li Y, Lao TT, Dai XQ, Zhang X. Numerical Simulation of Inner Stress Profiles and Deformations of Lower Extremity beneath Graduated Compression Stockings, Fibers and Polymers, 8(3), pp.301-308, 2007.
[7] Liu R, Kwok YL, Li Y, Lao TT, Zhang X, Dai XQ. Objective Evaluation of Skin Pressure Distribution of Graduated Elastic Compression Stockings. Dermatologic Surgery, 31(6), pp. 615-624, 2005.
[8] H Barhoumi, SMarzougui, SAbdessalem, SB Abdessalem. Clothing Pressure Modeling Using the Modified Laplace’s Law, Text Res J, Vol.38 (2), pp.134-147,2020.
[9] LMacintyre. Designing Pressure Garments Capable of Exerting Specific Pressures on Limbs. Burns, 33, pp. 579–586, 2007.
[10] Liu R, Kwok YL, Li Y, Lao TT, Zhang X. A Three-dimensional Biomechanical Model for Numerical Simulation of Pressure Functional Performances of Graduated Compression Stocking (GCS). Fibers and Polymers, 7(4), pp. 389-397, 2006.
[11] YB Shi, PLawford and R Hose, Review of Zero-D and 1-D Models of Blood Flow in the Cardiovascular System. Biomed Eng Online, 10.1 pp. 33, 2011.
[12] Wakiyama, S, Takano, Y, Shiba, H, Gocho, T, Sakamoto, T, Ishida, Y, and Yanaga, K. "Significance of Portal Venous Velocity in Short-term Graft Function in Living Donor Liver Transplantation." Transpl P 49.5, 2017.
[13] Ibegbuna, Veronica, Delis, Konstantinos T, Nicolaides, Andrew N, and Aina, Olayide. "Effect of Elastic Compression Stockings on Venous Hemodynamics during Walking." J Vasc Surg 37.2 ,2003.
[14] Audebert, Chloe, Peeters, Geert, Segers, Patrick, Laleman, Wim, Monbaliu, Diethard, Korf, Hannelie, Trebicka, Jonel, Vignon-Clementel, Irene E, and Debbaut, Charlotte. "Closed-Loop Lumped Parameter Modeling of Hemodynamics During Cirrhogenesis in Rats." IEEE T Cybernetics 65.10, 2018.
[15] L Dubuis, SAvril, JDebayle, P Badel, Identification of the Material Parameters of Soft Tissues in the Compressed Leg, Comput Methods Biomech Biomed Engin, 15(1), pp.3-11, 2012.
[16] KToya, T Takahashi, Y Fujimoto, T Nishimoto, T Takasoh, K Sasano, Ken, and SKusaka, Effect of Elastic Stockings and Ankle Positions on the Blood Velocity in the Common Femoral Vein, J PhysTherSci, 28.9 pp.608-610, 2016.