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Information Theoretical Analysis of Neural Spiking Activity with Temperature Modulation
Authors: Young-Seok Choi
Abstract:This work assesses the cortical and the sub-cortical neural activity recorded from rodents using entropy and mutual information based approaches to study how hypothermia affects neural activity. By applying the multi-scale entropy and Shannon entropy, we quantify the degree of the regularity embedded in the cortical and sub-cortical neurons and characterize the dependency of entropy of these regions on temperature. We study also the degree of the mutual information on thalamocortical pathway depending on temperature. The latter is most likely an indicator of coupling between these highly connected structures in response to temperature manipulation leading to arousal after global cerebral ischemia.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1105939Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1296
 W. Rosamond, K. Flegal, G. Friday, K. Furie, A. Go, K. Greenlund, N. Haase, M. Ho, V. Howard, B. Kissela, S. Kittner, D. Lloyd-Jones, M. McDermott, J. Meigs, C. Moy, G. Nichol, C. J. O'Donnell, V. Roger, J. Rumsfeld, P. Sorlie, J. Steinberger, T. Thom, S. Wasserthiel-Smoller, and Y. Hong, "Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee," Circulation, vol. 115, pp. e69-171, Feb 6 2007.
 H. C. Shin, S. Tong, S. Yamashita, X. Jia, R. G. Geocadin, and N. V. Thakor, "Quantitative EEG and effect of hypothermia on brain recovery after cardiac arrest," IEEE Trans Biomed Eng, vol. 53, pp. 1016-23, Jun 2006.
 "Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest," N Engl J Med, vol. 346, pp. 549-56, Feb 21 2002.
 S. A. Bernard, T. W. Gray, M. D. Buist, B. M. Jones, W. Silvester, G. Gutteridge, and K. Smith, "Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia," N Engl J Med, vol. 346, pp. 557-63, Feb 21 2002.
 X. Jia, M. A. Koenig, H. C. Shin, G. Zhen, C. A. Pardo, D. F. Hanley, N. V. Thakor, and R. G. Geocadin, "Improving neurological outcomes post-cardiac arrest in a rat model: immediate hypothermia and quantitative EEG monitoring," Resuscitation, vol. 76, pp. 431-42, Mar 2008.
 Y. S. Mednikova, N. V. Pasikova, and F. V. Kopytova, "Effects of temperature on the spike activity of cortical neurons in guinea pigs," Neurosci Behav Physiol, vol. 34, pp. 459-65, Jun 2004.
 Z. Nenadic and J. W. Burdick, "Spike detection using the continuous wavelet transform," IEEE Trans Biomed Eng, vol. 52, pp. 74-87, Jan 2005.
 R. Q. Quiroga, Z. Nadasdy, and Y. Ben-Shaul, "Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering," Neural Comput, vol. 16, pp. 1661-87, Aug 2004.
 C. Shannon, "A mathematical theory of communication," Bell Syst. Tech. J. , vol. 27, pp. 379-423/623-656, 1948.
 M. Costa, A. L. Goldberger, and C. K. Peng, "Multiscale entropy analysis of complex physiologic time series," Phys Rev Lett, vol. 89, p. 068102, Aug 5 2002.
 A. L. Goldberger, L. A. Amaral, L. Glass, J. M. Hausdorff, P. C. Ivanov, R. G. Mark, J. E. Mietus, G. B. Moody, C. K. Peng, and H. E. Stanley, "PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals," Circulation, vol. 101, pp. E215-20, Jun 13 2000.
 A. Kraskov, H. Stogbauer, and P. Grassberger, "Estimating mutual information," Phys Rev E Stat Nonlin Soft Matter Phys, vol. 69, p. 066138, Jun 2004.
 G. Buzsaki, "Large-scale recording of neuronal ensembles," Nat Neurosci, vol. 7, pp. 446-51, May 2004.
 S. M. Sherman, "A wake-up call from the thalamus," Nat Neurosci, vol. 4, pp. 344-6, Apr 2001.
 R. W. Hickey, P. M. Kochanek, H. Ferimer, H. L. Alexander, R. H. Garman, and S. H. Graham, "Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats," Crit Care Med, vol. 31, pp. 531-5, Feb 2003.