Case Series on Comparison Between Dexmedetomidine Versus Propofol as Pre Anaesthetic Medication for Awake Fibreoptic Intubation

Authors: Vanadana Gopal K., Harshalata Suryavanshi

Abstract:

Background: Awake fibreoptic intubation is a challenging procedure that requires effective sedation. Dexmedetomidine and propofol are two commonly used sedatives, but their comparative efficacy and safety in this setting are unclear. Methods: This retrospective case series compared the sedation quality, hemodynamic stability, and recovery profiles of 6 patients, three who received dexmedetomidine and three patients who received propofol for awake fibreoptic intubation. Results: Dexmedetomidine provided better sedation quality, hemodynamic stability, and faster recovery times compared to propofol. Additionally, dexmedetomidine resulted in a lower incidence of post-operative nausea and vomiting. Conclusion: Dexmedetomidine appears to be a suitable alternative to propofol for awake fibreoptic intubation, offering better sedation quality, hemodynamic stability, and recovery profiles. Further prospective studies are needed to confirm these findings.

Keywords: dexmedetomidine, propofol, hemodynamic stability, efficacy