Association of Selected Biochemical Markers and Body Mass Index in Women with Endocrine Disorders
Authors: M. Mydlárová Blaščáková, J. Bernasovská, J. Poráčová, I. Boroňová
Abstract:
Obesity is frequent attendant phenomenon of patients with endocrinological disease. Between BMI and endocrinological diseases is close correlation. In thesis we focused on the allocation of hormone concentration – PTH and TSH, CHOL a mineral element Ca in a blood serum. The examined group was formed by 100 respondents (women) aged 36 – 83 years, who were divided into two groups – control group (CG), group with diagnosed endocrine disease (DED). The concentration of PTH and TSH, Ca and CHOL was measured through the medium of analyzers Cobas e411 (Japan); Cobas Integra 400 (Switzerland). At individuals was measured body weight as well as stature and thereupon from those data we enumerated BMI. On the basis of Student T-test in biochemical parameter of PTH and Ca we found out significantly meaningful difference (p<0,05) between CG and DED. In CG we made a founding the association between BMI and PTH by means of correlation analysis.
Keywords: Biochemical markers, hormones, obesity, women.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1096125
Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2114References:
[1] J. Čáp, "Onemocnení hypotalamu a neurohypofýzy,” Postgraduální medicína, vol. 15, no. 7, pp. 701, July 2013.
[2] M. J. Bolland, A. B. Grey, G. D. Gamble, I. R. Reid, "Association between primary hyperparathyroidism and increased body weight: a metaanalysis," J Clin Endocrinol Metab., vol. 90, no. 3, pp. 1525–1530, March 2005.
[3] V. Zamrazil, "Nemoci štítne žlázy v klinické praxi,” Postgraduální medicína, vol. 15, no. 7, pp. 720 – 729, July 2013.
[4] G. Boden, G. I. Shulman, "Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction,” Eur J Clin Invest., vol. 32, no. 3, pp. 14 – 23, March 2002.
[5] T. Zima, A. Kazda, R. Průša, P. Štern, M. Aschermann, M. Babjuk et al., "Laboratórni diagnostika” 3. vyd. Praha: Galén, 2013, p. 906, ISBN 978-80-7492-062-2.
[6] Ch. Dreschler, D. C. Grootendorst, E. W. Boeschten, R. T. Krediet, Ch. Wanner, F. W. Dekker, "Changes in parathyroid hormone and body mass index and association with mortality in dialysis patients,” Nephrol Dial Transplant., vol. 19, no. 26, pp. 1340 – 1346, Sept. 2011.
[7] A. Dukát, "Metabolický syndróm predstavuje dnes jeden z najdôležitejších problémov súčasnej medicíny,” Súč klin pr., vol. 3, p. 2- 4, Sept. 2004.
[8] M. Roden, „Metabolic syndrom: a new epidemic? How to manage diabetes and cardiovascular diseases," 3rd International Meeting on Outcomes in Diabetes, Istanbul, Turkey. 15-16 November 2007.
[9] J. Jurkovičová, Ľ. Ághová, Z. Štefániková, "Perception of risk in relation to prevalence of cardiovascular disease risk factor in selected population group,” Homeostasis, vol. 40, no. 3 – 4, p. 139 – 141, April 2000.
[10] D. Dobrota, et al., "Lekárska biochémia,”. 1. vyd. Martin: Osveta, 2012, p. 723, ISBN 978-80-8063-293-9.
[11] E. Kamycheva, J. Sundsfjord, R. Jorde, „Serum parathyroid hormone level is associated with body mass index,” Eur J Endocrinol., vol. 151, no. 2, pp. 167 – 172, Feb. 2004.
[12] C. P. Kovesdy, S. Ahmadzadeh, J. E. Anderson, K. Kalantar-Zadeh, "Obesity is associated with secondary hyperparathyroidism,” Clin J Am Soc Nephrol., vol. 5 no. 2, p. 1024-1029, Sept. 2007.
[13] A. Solanki, S. Bansal, S. Jidal, V. Saxena, U. S. Shukla, "Relationship of serum thyroid stimulating hormone with body mass index in healthy adults,” Indian J Endocrinol Metab., vol. 17, no. 7, pp. 167 – 169, Oct 2013.
[14] C. M. Kitahara, E. A. Platz, P. W. Ladenson, A. M. Mondul, A. Menke, A. B. González, ”Body Fatness and Markers of thyroid function among U.S. men and women,” Plos One, vol. 7, no. 4, pp. 1 – 6, April 2012.
[15] L. Mehran, A. Amouzegar, H. Deshad, F. Azizi, "Association between serum TSH concentration and body mass index in euthyroid subject,” Arch Iran Med., vol. 15, no. 7, pp. 400-403, July 2012.
[16] A. Milionis, Ch. Milionis, "Correlation between body mass index and thyroid function in euthyroid individuals in Greece.” Online. Available: http://dx.doi.org/10.1155/2013/651494, May2014.