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Kinetic Study of Gluconic Acid Batch Fermentation by Aspergillus niger
Abstract:Gluconic acid is one of interesting chemical products in industries such as detergents, leather, photographic, textile, and especially in food and pharmaceutical industries. Fermentation is an advantageous process to produce gluconic acid. Mathematical modeling is important in the design and operation of fermentation process. In fact, kinetic data must be available for modeling. The kinetic parameters of gluconic acid production by Aspergillus niger in batch culture was studied in this research at initial substrate concentration of 150, 200 and 250 g/l. The kinetic models used were logistic equation for growth, Luedeking-Piret equation for gluconic acid formation, and Luedeking-Piret-like equation for glucose consumption. The Kinetic parameters in the model were obtained by minimizing non linear least squares curve fitting.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1073072Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2324
 J.Z. Liu, L.P. Weng, Q.L. Zhang, H. Xu, L. N. Ji, "A mathematical model for gluconinc acid fermentation by Aspergillus niger", Biochemical Engineering Journal, vol. 14, pp. 15-64, 2003.
 S. Velizarov, V. Beschkov, "Biotransformation of glucose to free gluconic acid by Gluconobacter oxydans: substrate and product inhibition situations", Process Biochemistry, vol. 33, no. 5, pp.527-534, 1998.
 H. Znad, J. Markos, V. Bales, "Production of gluconic acid from glucose by Aspergillus niger: growth and non-growth conditions", Process Biochemistry, vol. 39, pp. 1341-1345, 2004.
 M.L. Shuler, F. Kargi, Bioprocess Engineering Basic Concept. New Jersey: Prentice-Hall Inc., 1992, pp.176.
 T. Takamatsu, S. Shioya, T. Furuya, "Mathematical model of gluconic acid fermentation by Aspergillus niger", J. Chem.. Technol. Biotechnol., vol. 31, pp. 697-704, 1981.
 H. Znad, M. Blazej, V. Bales, J. Markos, "A kinetic model for gluconic acid production by Aspergillus niger", Chem. Pap., vol. 58, no. 1, pp. 23-28, 2004.