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Symmetry Breaking and the Emergence of Branching Structures in Morphogenesis: Minimal Conditions and Mechanical Interactions between Cells

Authors: M. Margarida Costa, Jorge Simão


The minimal condition for symmetry breaking in morphogenesis of cellular population was investigated using cellular automata based on reaction-diffusion dynamics. In particular, the study looked for the possibility of the emergence of branching structures due to mechanical interactions. The model used two types of cells an external gradient. The results showed that the external gradient influenced movement of cell type-I, also revealed that clusters formed by cells type-II worked as barrier to movement of cells type-I.

Keywords: Morphogenesis, branching structures, symmetrybreaking

Digital Object Identifier (DOI):

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