Commenced in January 2007
Paper Count: 32146
An Experimental Design Approach to Determine Effects of The Operating Parameters on The Rate of Ru promoted Ir Carbonylation of Methanol
Abstract:carbonylation of methanol in homogenous phase is one of the major routesfor production of acetic acid. Amongst group VIII metal catalysts used in this process iridium has displayed the best capabilities. To investigate effect of operating parameters like: temperature, pressure, methyl iodide, methyl acetate, iridium, ruthenium, and water concentrations on the reaction rate, experimental design for this system based upon central composite design (CCD) was utilized. Statistical rate equation developed by this method contained individual, interactions and curvature effects of parameters on the reaction rate. The model with p-value less than 0.0001 and R2 values greater than 0.9; confirmeda satisfactory fitness of the experimental and theoretical studies. In other words, the developed model and experimental data obtained passed all diagnostic tests establishing this model as a statistically significant.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1333536Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 3431
 SRI Consulting, Process Economic Program, Methanol and Derivatives, Vol 3, 2009.
 Noriyuki Yoneda, Satoru Kusano, Makoto Yasui, Peter Pujado, Steve Wilcher. "Recent advances in processes and catalysts for the production of acetic acid".Applied Catalysis A: General, volume: 221 (2001). pp: 253-265.
 Hua Jiang, Zhongyang Liu, Pinglai Pan, Guoqing Yuan,"A novel supported catalyst for the carbonylation of methanol"Journal of Molecular Catalysis A: Chemical. 148 (1999) 215-225.
 Glenn J. Sunley, Derrick J. Watson."High productivity methanol carbonylation catalysis using iridium The CativaTM process for the manufacture of acetic acid".Catalysis Today, Volume: 58 (2000). pp: 293-307.
 Christophe M. Thomas, Georg Suss-Fink." Ligand effects in the rhodium-catalyzed carbonylation of methanol". Coordination Chemistry Reviews. Volume: 243 (2003).pp: 125-142.
 Anthony Haynes, Peter M. Maitlis, George E. Morris, Glenn J. Sunley, Harry Adams, Peter W. Badger, Craig M. Bowers, David B. Cook, Paul I. P. Elliott, TalitGhaffar, Helena Green, Tim R. Griffin, Marc Payne, Jean M. Pearson, Michael J. Taylor, Paul W. Vickers, and Rob J. Watt."Promotion of iridium-catalyzed methanol carbonylation: mechanistic studies of the cativa process". Journal of American Chemical Society. Volume: 126(2004). pp: 2847-2861.
 R.L. Mason, R.F. Gunst, J.L. Hess, Statistical Design and Analysis of Experiments with Applications to Engineering and Science, 2nd ed.,John Wiley & Sons, USA, 2003.
 Zivorad R. Lazic, Design of Experiments in Chemical Engineering, WILEY-VCHVerlag GmbH & Co. KGaA, Germany, 2004.
 C. Montgomery, Design and Analysis of Experiments, 4th ed., John Wiley & Sons, USA, 1996.