Commenced in January 2007
Paper Count: 31598
Thermo-Mechanical Characterization of Skin Laser Soldering using Au Coated SiO2 Nanoshells
Abstract:Gold coated silica core nanoparticles have an optical response dictated by the plasmon resonance. The wavelength at which the resonance occurs depends on the core and shell sizes, allowing nanoshells to be tailored for particular applications. The purposes of this study was to synthesize and use different concentration of gold nanoshells as exogenous material for skin tissue soldering and also to examine the effect of laser soldering parameters on the properties of repaired skin. Two mixtures of albumin solder and different concentration of gold nanoshells were prepared. A full thickness incision of 2×20 mm2 was made on the surface and after addition of mixtures it was irradiated by an 810nm diode laser at different power densities. The changes of tensile strength σt due to temperature rise, number of scan (Ns), and scan velocity (Vs) were investigated. The results showed at constant laser power density (I), σt of repaired incisions increases by increasing the concentration of gold nanoshells, Ns and decreasing Vs. It is therefore important to consider the trade off between the scan velocity and the surface temperature for achieving an optimum operating condition. In our case this corresponds to σt =1610 gr/cm2 at I~ 60 Wcm-2, T ~ 65ºC, Ns =10 and Vs=0.2mms-1.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1063198Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1302
 M.Gulsoy , Z.Dereli , H.Tabakogh, "closure of skin incisions by 980 nm diode laser welding". Lasers Med Sci ., vol.2, no.1, pp. 5-10 2006.
 M.McNally, B.S.Sorg , E.K.Chan , A.J.Welch , J.M.Dawes, "Optimal parameters for laser tissue soldering. Part I: Tensile strength and scanning electron microscopy analysis". Lasers Surg Med., vol. 26, no.4, pp. 346 - 356,2000.
 S.D. DeCoste, W. Farinelli, T. Flotte, R.R. Anderson , "Dye enhanced laser welding for skin closure". Lasers Surg Med., vol. 12, no.1, pp. 25- 32,1992.
 L.S. Bass , "Laser tissue welding: A comprehensive review of current and future clinical applications", Lasers Surg Med., vol.17, no.4, pp.315-349, 1995.
 D.Spector, Y.Rabi, I.Vasserman, ,A. Hardy, J.Klausner,A. Katzir, " In vitro large diameter bowel anastomosis using a temperature controlled laser tissue soldering system and albumin stent",Lasers Surg Med., vol. 41, no.7, pp.504-508,2009.
 A.C.O'Neill, J.M.Winograd, J.L.Zeballos, M.A.Randolph, K.E.Bujold, I.E.Kochevar, R.W.Redmond, "Microvascular anastomosis using a photochemical tissue bonding technique". Lasers Surg Med., vol.39, no.9, pp. 716 - 722,2007
 B.Zuger, B.Ott, Th. Schaffner, J.Clemence, " Laser solder welding of articular cartilage: Tensile strength and chondrocyte viability". Lasers surg Med ., vol.28, no.5,pp.427-434,2001.
 D.Simhon, M. Halpern.,T. Brosh, T.Vasilyev, N.Kariv, R.Argaman, A.Katzir , "In vivo laser soldering of incisions in juvenile pig skin, using GaAs or CO2 lasers and a temperature control system", SPIE Proc. vol. 5312, pp.162-175,2004.
 M.E.Khosroshahi, M.S.. Nourbakhsh, S. Saremi, F. Tabatabaee F, "Characterization of skin tissue soldering using diode laser and ICG: Invitro studies", Laser Med Sci., vol.25,no.2, pp.207-212, 2010.
 D.Duff, A.Baiker,P.Edwards, "A new hydrogel of gold cluster formation and particle size variation", Langmuir, vol.9, no.9, pp.2301-2309,1993.
 J.M. Stern, J.Stanfield ,W. Kabbani , "Selective prostate cancer thermal ablation with laser activated gold nanoshells". J Urol., vol. 179, no.2, pp.748-753,2008.
 Y.Wang, W.Qian, Y.Tan , "A label-free biosensor based on gold nanoshell monolayers for monitoring biomolecular interactions in diluted whole blood". Biosens Bioelectron vol.23, no.7, pp.1166-1170, 2008.
 L.R.Hirsch, R.J. Stafford, J.A. Bankson, S.R. Sershen, B.Rivera,R.E.Price, J.D.Hazle , N.J.Halas, J.L.West , "Nanoshellmediated near-infrared thermal therapy of tumors under magnetic resonance guidance" , Proc. Natl.Acad .Sci. USA,vol. 100, no.23,pp.13549-13554, 2003.
 D.P.O-Neal , L.R.Hirsch , N.J.Halas, J.D. Payne ,"Photothermal tumor ablation in mice using near infrared-absorbing nanoparticles", Cancer Lett ., vol. 209, no.2, pp.171-176.2004.
 D.K. Dew, R.Serbent, W.S.Hart, G.C. Boynton, J.D.Byrne ,J.G.Evans "Laser assisted microsurgical vessel anastomosis techniques: The use of argon and CO2 lasers". Lasers Surg Med , vol.3, no.2, pp.135-137, 1983.
 M.S.Nourbakhsh, M.E.Khosroshahi,, S. Saremi, F. Tabatabaee F., " Effect of static and dynamic modes on laser tissue soldering: an in-vitro study", NBC proceedings vol.20, pp.2383-385, 2008.
 R.A.Alvarez-Puebla, D.J.Ross, G.A.Nazri, R.F.Aroca , "Surface- Enhanced Raman Scattering on Nanoshells with Tunable Surface Plasmon Resonance", Langmuir , vol.21, no.23, pp. 10504-10508, 2005.