Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 31598
Antibacterial Capacity of Plumeria alba Petals

Authors: M. H. Syakira, L. Brenda


Antibacterial activity of Plumeria alba (Frangipani) petals methanolic extracts were evaluated against Escherichia coli, Proteus vulgaris,Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus saprophyticus, Enterococcus faecalis and Serratia marcescens by using disk diffusion method. Concentration extracts (80 %) showed the highest inhibition zone towards Escherichia coli (14.3 mm). Frangipani extract also showed high antibacterial activity against Staphylococcus saprophyticus, Proteus vulgaris and Serratia marcescens, but not more than the zones of the positive control used. Comparison between two broad specrum antibiotics to frangipani extracts showed that the 80 % concentration extracts produce the same zone of inhibition as Streptomycin. Frangipani extracts showed no bacterial activity towards Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterococcus faecalis. There are differences in the sensitivity of different bacteria to frangipani extracts, suggesting that frangipani-s potency varies between these bacteria. The present results indicate that frangipani showed significant antibacterial activity especially to Escherichia coli.

Keywords: Frangipani, Plumeria alba, anti microbial, Escherichia coli

Digital Object Identifier (DOI):

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2215


[1] Asolkar LV, Kakkar KK, Chakre OJ.(1992) Second Supplement to Glossary of Indian medicinal plants with active principles; pp.173
[2] Amani S, Isla MI, Vattuone M, Poch M, Cudmani N, Sampietro A (1998). Antimicrobial activities in some Argentine Medicinal Plants. Acta Horticulture. 501:115-122.
[3] Arias ME, Gomez JD, Cudmani N, Vattuone MA, Isla MI (2004). Antibacterial activity of ethanolic and aqueous extract of Acacia aroma Gill ex Hook et. Life Science.
[4] Baron, Samuel 1996. Medical Microbiology, 4th ed., The University of Texas Medical Branch at Galveston.75:191-202.
[5] Barrett, S.P., M.A. Savage, M.P. Rebec, N. Guyot A Andrews and S.B. Shrimpton, 2000. Antibiotic sensitivity of bacteria associated with communityacquired urinary tract infection in Britain. J. Antimicrob. Chemother, 44: 359-365
[6] Barton, M.D., 1998. Does the use of antibiotics in animals affect human health? Aust. Vet. J., 76: 177- 180.
[7] Bonten, M., E. Stobberingh, J. Philips and A. Houben, 1992. Antibiotic resistance of Escherichia coli in fecal samples of healthy people in two different areas in an industrialized country. Infection, 20: 258- 262.
[8] Cushnie TP, Lamb AJ (2005). Anti microbial activities of flavonoids. Int. J. Antimicrob. Agents 26:343.
[9] Edward F. Gilman and Dennis G. Watson (October 1994). Plumeria alba White Frangipani.
[10] Essawi T, Srour M (2000). Screening of some Palestinian medicinal plants for antibacterial activity. J. Ethnopharmacol. 70:343-349.
[11] Fluit, A.C., M.E. Jones, F.J. Schmitz, J. Acar, R. Gupta and J. Verhoef, 2000. Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY antimicrobial surveillance program, 1997 and 1998. Clin. Infect. Dis., 30: 454- 460.
[12] George M Beringer, 1895. AMERICAN JOURNAL OF PHARMACY. The APOCYNACEAE in materia medica - Volume 67, #3, March, 1895 - Page 18
[13] Hamil FA, Apio S, Mubiru NK, Bukenya-Ziraba R, Mosango M, Maganyi OW, Soejarto DD (2003). Traditional herbal drugs of southern uganda, II : Literature análysis and antimicrobial assays. J. Ethnopharmacol. 84:57-78.
[14] Hartwell JL. Plants used against cancer (A survey) Quarterman Publications, Inc. Lawrence, Massachu setts. 1982; pp.408.
[15] Henry AN, Kumeri GR, Chitra V. Flora of Tamil Nadu, India. 1987; pp.78.
[16] Hooton, T. M., and W. E. Stamm. 1997. Diagnosis and treatment of uncomplicated urinary tract infection. Infect. Dis. Clin. N. Am. 11:551- 581
[17] Huouinen P.2001.Bacteriotherapy: The time has come.BMJ.323:353- 354.
[18] Ika¨heimo, R., A. Siitonen, T. Heiskanen, U. Karkkainen, P. Kuosmanen, P. Lipponen, and P. H. Makela. 1996. Recurrence of urinary tract infection in a primary care setting: analysis of a 1-year follow-up of 179 women. Clin.Infect. Dis. 22:91-99.
[19] Izzo AA (2004). Drug interactions with St. John-s wort (Hypericum perforation): A review of the clinical evidence. Int. J. Clin. Pharmacol. Thera 42:139-148.
[20] Machado T B, Pinto A V, Pinto M C F R, Leal I C R, Silva M G, Amaral A C F, Kuster R M, Netto - dosSantos K R (2003). Invitro activity of Brazilian medicinal plants, naturally occurring naphthoqinones and their analogues, against methicillin-resistant staphylococcus aureus. Int. J. of Antimicrobial Agents 21:279-284.
[21] Kodera, Y.1997.Ch.11.In: Nutraceuticals: Designer Foods III Garlic, Soy and Licorice, Trumbell, Ct: Food & Nutrition Press), Paul Lanchance; ed.,pp.95-105
[22] Julia F. Morton, Director, Morton. Collectanea University of Miami Coral Gables, Ornamental flowers with toxic and/or irritant properties,1962
[23] McKeon, D.M., J.P. Calabrese and G.K. Bissonnette, 1995. Antibiotic resistant gram-negative bacteria in rural ground water supplies. Water Res., 29: 1902- 1908.
[24] Meng JC, Zhu QX, Tan RX (2000). New antimicrobial mono- and sesquiterpenes from soroseris hookeriana Subsp.erysimoides. Planta Medica 66: 541-544.
[25] M.P Darokar , A.Mathur, S. Dwivedi, R. Bhalla, S.P.S Khanuja, Sushil Kumar, Currents Science Volume, 75, No 3, 1998
[26] Neu, H.C., 1992. The crisis in antibiotic resistance. Sci., 257: 1064- 1073.
[27] New Directions Laboratory of Australia, Certificate of Analysis and Material Safety Data Sheet, Frangipani Absolute - Batch R1742 - BCRO1 (2006)
[28] Olaleye, Mary Tolulope (2007). Cytotoxocity and antibacterial activity of Methanolic extract of Hibiscuss sabdariffa. Journal of Medicinal Plants Research.1: 009 - 013
[29] Ordonez AA, Cudmani NM, Gomez D, Vattuone MA, Isla MI (2003). Antimicrobial activity of nine extracts of sechium edule (Jacq) Swartz. Microbiology Ecology in Health and Disease 15:33-39.
[30] ├ûsterberg E, Hallander HO, Kallner A, Lundin A, Svensson SB, Åberg H. Female urinary tract infection in primary health care: bacteriological and clinical characteristics. Scand J Infect Dis 1990; 22: 477-484.
[31] Poyart-Salmeron C, Carlier C, Trieu-cuot P, Courtieu A L, Courvalin P (1990). Transferable plasmid - mediated antibiotic resistance in Listeria monocytogenes. The Lancet 335:1422-1426.
[32] Rasool S.N, Jaheerunnisa S, Kumar Chitta and Jayaveera K.N (2008), Antimicrobial activities of Plmeria acutfolia. Journal of Medicinal Plants Research; 2: 077 - M. Young, The Techincal Writers Handbook. Mill Valley, CA: University Science, 1989.
[33] Reid G; Bruce. 2003. Urogenital infection in women: can probiotics help? Post graduate medical journal.79:428-432.
[34] Salvat A, Antonnacci L, Fartunato RH, Suarez EY, Godoy HM (2001). Screening of some plants from Northern Argentina for their antimicrobial activity. Letters in Applied Microbiology 32: 293-297
[35] W. Rizvi, A. Kumar, R. Kumar, N. Haider. 2010. Evaluation of Anti filarial activity in roots of Plumeria alba.Proceedings of the 6th Conference of Medicinal and Aromatic Plants of Southeast European countries. pp 132