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Evaluation of the Antifungal and Antioxidant Activities of the Leaf Extract of Aloe vera(Aloe barbadensis Miller)

Authors: Tin A. Khaing

Abstract:

Aloe vera has been used worldwide both for pharmaceutical, food, and cosmetic industries due to the plethora of biological activities of some of its metabolites. The aim of this study was to evaluate the antifungal and antioxidant activities of the leaf extract. The antifungal activity was determined by the agar-well diffusion method against plant and human fungal pathogens. The methanol and ethanol portions of the extracts studied were more bioactive than ethyl acetate portion. It was also observed that the activity was more pronounced on plant pathogen than human pathogen except Candida albicans. This is an indication that the extract has the potential to treat plant fungal infections. The Aloe extract showed the significant antioxidant activity by the DPPH radical scavenging method. Therefore, the Aloe extract provided as natural antioxidant has been used in health foods for medical and preservative purposes.

Keywords: Aloe vera, antifungal, antioxidant, DPPH

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1057581

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References:


[1] B. Mahesh and S. Satish, "Antimicrobial activity of some important medicinal plant against plant and human pathogens," World J. Agri.Sci., vol. 4, no. 5, pp. 839-843, 2008.
[2] B. Halliwell, R. Aeschbach, J. Lo Liger and O.I. Aruoma, "The characterization of antioxidant," Food Chem. Toxicol., vol. 33, pp. 601- 617, 1995.
[3] A. Mann, A. Banso , L.C. Clifford, "An Antifungal property of crude plant extracts from Anogeissus leiocarpus and Terminalia avicennioides," Tanzania J. Health Res., vol.10, no. 1, pp. 34-38, 2008.
[4] M. B. Ibrahim, "Anti-microbial effects of extract leaf, stem and root bark of Anogeissus leiocarpus on Staphylococcus aureaus, Streptococcus pyogenes, Escherichia coli and Proteus vulgaris," J. Pharma. Devpt., vol. 2, pp. 20-30, 1997.
[5] O. Ogundipe, O. Akinbiyi, J. O. Moody, "Antibacterial activities of essential ornamental plants," Nigeria J. Natural Products & Medicine., vol. 2, pp. 46-47, 1998.
[6] T. Reynolds, Bot. J. Linn. Soc., vol. 90, pp. 157, 1985.
[7] D. Grindly, T. Reynolds, J. Ethnopharmacology, vol. 16, pp. 117, 1986.
[8] Jr. J. S. Haller, Bulletin of the New York Academy of Medicine, vol. 66, pp. 647, 1990.
[9] U. Eggli, Illustrated Handbook of Succulent Plants: Monocotyledons, Springer, 2001.
[10] L.G. Plaskett, "Aloe vera against infections", Newsletter 9, Publ. Biomedical Information Services Ltd., Launceston, Cornwall, UK, 1997.
[11] K. Fujita, R. Teradaira, T. Nagatsu, "Bradykinase activity in Aloe extract", Biochemical Pharmacology, vol. 25, pp. 205, 1976.
[12] K. R. Anilakumar, K. R. Sudarshanakrishna, G. Chandramohan, Ilaiyaraja, K. Farhath, A. S. Bawa, "Effect of Aloe vera gel extract on antioxidant enzymes and azoxymethane-induced oxidative stress in rats," Ind. J. Expt. Biol., vol. 48, pp. 837-842, 2010.
[13] B. Vazquez, G. Avila, D. Segura, B. Edcalante, "Antiinflammatory activity of extracts from Aloe vera gel," J. Ethanopharmacol, vol . 55, pp. 9-15, 1996.
[14] Yun, N. Nasi, Lee, C. H. Chan-Ho, S. M. Sun-Meec, "Aloe vera could be a potential therapeutic agent for the clinical treatment of sepsis," Food Chem. Toxicol., vol. 47, pp. 1341-1350, 2009.
[15] A. B. K. Chandan, Z. A. K Saxena, S. Sukla, N. Sharma, D. K. Gupta, K. A. Suri, J. Suri, M. Bahauria, B. Singh, " Hepatoprotective potential of Aloe barbedensis Mill. Against carbon tetrachloride induced heptatotoxicity," J. Ethanopharmacol., vol. 11, pp. 560-569, 2007.
[16] L. Zhang, I. R. Tizard, "Activation of a mouse microphage cell line by acemannan: the major carbohydrate fraction from Aloe vera gel," Immuno. Phar., vol. 35, pp. 119-128, 1996.
[17] P. Amruta , G. K. Purushottam, " Alteration in the antioxidant Potential of Aloe vera Due to Fungal Infection," Plant Pathology J., vol. 6, no. 2, pp. 169-173, 2007.
[18] W. B. Williams, M. Cuvelier, C. Berset, "Use of a free radical method to evaluate antioxidant activity," Lebensm-Wiss Technol, vol. 28, pp. 25- 30, 1995.
[19] A. B. Ribeiro, V. S. Bolzani, M. Yoshida, L. S. Santos, M. N. Eberlin, D. H. S. Silva, "A new neolignan and antioxidant phenols from Nectandra grandiflora," J. Braz. Chem. Soc., Vol. 16, pp. 526-530, 2005.
[20] D. Jasso de Rodriguez, D. Hernandez-Castillo, R. Rodriguez-Garcia, J. L. Angulo-Sanchez, "Antifungal activity in vitro of Aloe vera pulp and liquid fraction against plant pathogenic fungi," Ind. Crops Prod., vol. 21, no. 1, pp. 81-87, 2005.
[21] V. Saritha, K. R. Anilakumar, F. Khanum, "Antioxidant and antibacterial activity of Aloe vera gel extracts," Int. J. Pharmaceutical &Bio. Arch., vol. 1, no. 4, pp. 376-384, 2010.