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Stability and Bifurcation Analysis in a Model of Hes1 Selfregulation with Time Delay

Authors: Kejun Zhuang, Hailong Zhu


The dynamics of a delayed mathematical model for Hes1 oscillatory expression are investigated. The linear stability of positive equilibrium and existence of local Hopf bifurcation are studied. Moreover, the global existence of large periodic solutions has been established due to the global bifurcation theorem.

Keywords: Hopf Bifurcation, Time Delay, Hes1, transcriptional repression loop

Digital Object Identifier (DOI):

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