Relationship between Functional Gastrointestinal Disorders and Risk Factors: A Biomechanical Analysis
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 32807
Relationship between Functional Gastrointestinal Disorders and Risk Factors: A Biomechanical Analysis

Authors: Dae Gon Woo, Han Sung Kim, Dohyung Lim, Dong Jin Seo, In Deok Kong, Chang Yong Ko

Abstract:

Functional gastrointestinal disorders (FGID) affect millions of people spread all age regardless of race and sex. Emotional stress and obesity have been associated with increased reporting of gastrointestinal (GI) symptoms, but the relationship between FGID and risk factors (emotional stress or obesity) is unclear. Our aim was to assess the changes of the mechanical characteristics on the gastrointestinal tracts of the mentally fatigued obese and normal rat models. Finally, using the physical characteristics with micro-indentation test, we made a close investigation into the relation between FGID and risk factors quantitatively.

Keywords: Functional gastrointestinal disorders, Risk Factors, Mechanical Characteristics, Gastrointestinal Tract.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1055831

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1571

References:


[1] S. Haag, ''Symptom patterns in functional dyspepsia and irritable bowel syndrome: relationship to disturbances in gastric emptying and response to a nutrient challenge in consulters and non-consulters,'' Gut, vol. 53, pp. 1445-1451, 2004.
[2] N. J. Talley, ''Symptom patterns in functional dyspepsia and irritable bowel syndrome: relationship to disturbances in gastric emptying and response to a nutrient challenge in consulters and non-consulters,'' Am J Gastroenterol., vol. 99, pp. 1807-1814, 2004.
[3] F. Cremonini, ''Relationship between upper gastrointestinal symptoms and changes in body weight in a population-based cohort,'' Neurogastroenterol Motil., vol. 18, pp. 987-994, 2006.
[4] K. M. Flegal, ''Prevalence and trends in obesity among US adults,'' JAMA, vol. 288, pp. 1723-1727, 2002.
[5] M. Nilsson, ''Obesity and estrogen as risk factors for gastroesophageal reflux symptoms,'' JAMA, vol. 290, pp. 66-72, 2003.
[6] J. Lagergren, ''No relation between body mass and gastro-oesophageal reflux symptoms in a Swedish population based study,'' Gut, vol. 47, pp. 26-29. 2000.
[7] M. Nilsson, ''Body mass and reflux oesophagitis: an oestrogen-dependent association?'' Scand J Gastroenterol., vol. 37, pp. 626-630, 2002.
[8] G. R. Locke, ''Risk factors associated with symptoms of gastroesophageal reflux,'' Am J Med., vol. 106, pp. 642-649, 1999.
[9] H. M?nnikes, ''Role of Stress in Functional Gastrointestinal Disorders Evidence for Stress-Induced Alterations in Gastrointestinal Motility and Sensitivity,'' Digestive diseases, vol. 19, no. 3, pp. 201-211, 2001.
[10] R. L. Levy, ''Psychosocial Aspects of the Functional Gastrointestinal Disorders,'' Gastro., vol. 130, pp. 1447-1258, 2006
[11] K. W. Min, ''Interstitial Cells of Cajal (ICC) and Gastrointestinal Stromal Tumor (GIST): facts, speculations, and myths,'' J. Cell Mol Med., vol. 10, pp. 995-1013, 2006.
[12] M. Takaki. ''Cut pacemaker cells: the interstitial cells of cajal (ICC),'' J. Smooth Muscle Res., vol. 39, pp. 137-161, 2003.
[13] K. D. Keef, ''Basal release of nitric oxide induces an oscillatory motor pattern in canine colon,'' J. Physiol., vol. 499, pp. 773-786, 1997.
[14] T. K. Smith, ''Interaction of two electrical pacemakers in the muscularis of the canine proximal colon,'' Am. J. Physiol., vol. 252, pp. 290-299, 1987.
[15] A. C. Guyton, Textbook of medical physiology. 10 ed. W.B. Saunders, Philadelphia, 2000.