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Effects of Bay Leaves on Blood Glucose and Lipid Profiles on the Patients with Type 1 Diabetes
Authors: Abdulrahim Aljamal
Abstract:Bay leaves have been shown to improve insulin function in vitro but the effects on people have not been determined. The objective of this study was to determine if bay leaves may be important in the prevention and/or alleviation of type 1 diabetes. Methods: Fifty five people with type 1 diabetes were divided into two groups, 45 given capsules containing 3 g of bay leaves per day for 30 days and 10 given a placebo capsules. Results All the patients consumed bay leaves shows reduced serum glucose with significant decreases 27% after 30 d. Total cholesterol decreased, 21 %, after 30 days with larger decreases in low density lipoprotein (LDL) 24%. High density lipoprotein (HDL) increased 20% and Triglycerides also decreased 26%. There were no significant changes in the placebo group. Conclusion, this study demonstrates that consumption of bay leaves, 3 g/d for 30 days, decreases risk factors for diabetes and cardiovascular diseases and suggests that bay leaves may be beneficial for people with type 1 diabetes.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1083631Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 2103
 Grundy S.M. Metabolic syndrome: connecting and reconciling cardiovascular and diabetes worlds. J. Am. Coll. Cardiol. 2006;47:1093- 1100.
 Srinivasan K. Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. Int. J. Food Sci. Nutr. 2005;56:399-414.
 Khan A., Bryden N.A., Polansky M.M., Anderson R.A. Insulin potentiating factor and chromium content of selected foods and spices. Biol. Trace Elem. Res. 1990;24:183-188.
 Bailey C.J., Day C. Traditional plant medicines as treatments for diabetes. Diabetes Care. 1989;12:553-564.
 Arteriosclerosis. A report of by the National Heart and Lung Institute Task force on Arteriosclerosis Department of Health. Education and welfare Publication (NIA) 1971. 72- 137. Washington DC. National nstitute of Health, Vol.1.
 Coronary Drug Project Research Group. The coronary drug project. Clofibrate and Niacin in coronary heart disease. JAMA. 1975231:360- 381.
 Turpana, O. 1979. Effect of cholesterol lowering diet on mortality from coronary heart disease and other causes. Circulation. 59:1-7.
 Lipid Research Clinics Programme. The Lipid Research Clinics Coronary Primary Prevention Trial Results. II: The relationships of reduction in the incidence of coronary heart disease to cholesterol. JAMA. 1984.25: 365-374.
 Shaten, B.J., Kuller, L.H. and Neaton, J.D. Association between baseline risk factors, cigarette smoking, and CHD mortality after 10.5 years. Prev. Med. 1991. 20:655-669.
 Castelli, W.P., Anderson, K., Wilson, P.W. and Levy, D. Lipid risk of coronary heart disease: The Framingham Study. Ann. Epidemiol. 1992. 2:23-28.
 Wargovich, M.J., Woods, C., Hollis, D.M. and Zander, M.E. 2001. Herbals, cancer prevention and health. J. Nutr. 131: 3034S-3036S.
 Fang Fang, Shengmin Sang, Kuang Y. Chen, Alexander Gosslau, Chi- Tang Ho, Robert T. Rosen. Isolation and identification of cytotoxic compounds from Bay leaf (Laurus nobilis) Food Chemistry. 2005. 93 497-501
 Yalcin H., Anik M., Sanda M.A., Cakir A. Gas chromatography/mass spectrometry analysis of Laurus nobilis essential oil composition of northern Cyprus. J. Med. Food. 2007;10:715-719.
 Broadhurst C.L., Polansky M.M., Anderson R.A. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J. Agric. Food Chem. 2000;48:849-852.
 Wall M.E., Wani M.C., Brown D.M., Fullas F. Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal. Phytomedicine. 1996;3:281-285.
 Anderson R.A. Chromium and polyphenols from cinnamon improve insulin sensitivity. Proc. Nutr. Soc. 2008;67:48-53.
 Decker, E.A. The role of phenolics, conjugated linoleic acid, carnosine, and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutr. Rev. 1995.53:49-56.
 Nofer, J.R., Kehrel, B., Fobker, M., Levkau, B., Assmann, G.and von Eckardstein, A. HDL and arteriosclerosis:beyond reverse cholesterol transport. Atherosclerosis. 2002.161:1-16.
 Parthasarathy, S., Barnett, J. and Fong, L.G. High-densitylipoprotein inhibits the oxidative modification of lowdensity lipoprotein. Biochem. Biophys. Acta. 1990. 1044:275-285.
 Mackness, M.I. and Durrington, P.N. HDL, its enzymes and its potential to influence lipid peroxidation.Atherosclerosis. 1995.115:243-253.
 Mackness, M.I., Arrol, S., Abbott, C. and Durrington, P.N. Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase. Atherosclerosis. 1993. 104:129-135.
 Mooradian A D & Morin A M, Brain uptake of glucose in diabetes mellitus: The role of glucose transporters, Am J Med Sci, 1990. 30. 173.
 S Lakshmi Devi, S Kannappan & C V Anuradha. Evaluation of in vitro antioxidant activity of Indian bay leaf, Cinnamomum tamala (Buch. - Ham.) T. Nees & Eberm using rat brain synaptosomes as model system. 2007. Indian Journal of Experimental Biology Vol. 45, September. 778- 784.
 Draznin B & Eckel RH, Diabetes and atherosclerosis, in Molecular basis and clinical aspects (Elsevier Publishers, New York) 1993, 203.
 Celik S & Ozkaya A, Effects of intraperitoneally administered lipoic acid, vitamin E and linalool on the level of total lipid and fatty acids in guinea pig brain with oxidative stress induced by H2O2. J Biochem Mol Biol, 2002. 35 547.