Effects of the Intermittent Exercise Programs on Lipid Profile and Anthropometric Characteristics at Obese Young Subjects

Authors: Vasilescu M., Rusu L, Balseanu TA., Cosma G., Dragomir M.

Abstract:

The aim of our research was to evaluate the effects of physical exercise on lipid profile and anthropometric characteristics in young subjects, diagnosed with metabolic syndrome (MS). The study has been developed during 28 weeks on 20 young obese patients which have undertaken an intermittent submaximal exercise program. After 28 weeks of physical activity, the results show significant effects on anthropometric characteristics and serum lipid profile of research subjects. Additionally, the results of this study confirms the major correlation between the variations of intraabdominal adiposity, determined ultrasonographycally, and the changes of serum lipid concentrations, a better correlation than it is used abdominal circumference or body weight index.

Keywords: lipid metabolism, adiposity, physical exercise

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1080576

References:

[1] Cornier MA, Dabelea D., Hernandez T Letal. (2008). The Metabolic Syndrome. Endocrine Reviews 29:777-822.
[2] Grundy SM, Brewer HB Jr, Cleeman JI, Smith SC Jr, Lenfant C. (2004). Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/ American Heart Association conference on scientific issues related to definition. Circulation; 109: 433-438.
[3] Lorenzo C, Williams K, Hunt KJ, Haffner SM (2007). The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes. Diabetes Care; 30:8-13.
[4] Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).(2001) JAMA; 285: 2486-2497.
[5] Grundy SM, Cleeman JI, Daniels SR et al. (2005). Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation; 112: 2735-2752.
[6] Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Final report (2002). Circulation; 106: 3143-3421.
[7] Hunt KJ, Resendez, Williams K, Haffner SM, Stern MP (2004). National Cholesterol Education Program versus World Health Organization metabolic syndrome in relation to all-cause and cardiovascular mortality in the San Antonio Heart Study. Circulation 110: 1251-1257.
[8] R. Kahn, J. Buse, E. Ferrannini, and M. Stern (2005). The Metabolic Syndrome: Time for a Critical Appraisal: Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care; 28(9): 2289 - 2304.
[9] Vague J. La differénciation sexuelle, facteur determinant des formes de l-obésité. Presse méd., 1947, 55:339-340.
[10] Bergman RN, Kim SP, Catalano KJ, Hsu IR, Chiu JD, Kabir M, Hucking K, Ader M. Why Visceral Fat is Bad: Mechanisms of the Metabolic Syndrome, Obesity, 2006, 14, 16S-19S.
[11] Fisher, S. J., Kahn, CR, Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production. J Clin Invest, 2003,111: 463-468.
[12] Rizza, R. A., Mandarino, L. J., Genest, J., Baker, B. A., Gerich, JE, Production of insulin resistance by hyperinsulinaemia in man, Diabetologia, 1985, 28: 70-75.
[13] Miyazaki Y, Defronzo RA, Visceral fat dominant distribution in male type 2 diabetic patients is closely related to hepatic insulin resistance, irrespective of body type, Cardiovascular Diabetology, 2009, 8:44.
[14] Gastaldelli A, Cusi K, Pettiti M, Hardies J, Miyazaki Y, Berria R, Buzzigoli E, Sironi AM, Cerosimo E, Ferrannini E, Defronzo RA, Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects, Gastroenterology, 2007, 133:496-506.
[15] Armellini F, Zamboni M, Rigo L, et al, The contribution of sonography to the measurement of intraabdominal fat. J Clin Ultrasound, 1990; 18:563-567.
[16] Ribeiro-Filho FF, Faria AN, Azjen S, Zanella MT, Ferreira SR, Methods of estimation of visceral fat: advantages of ultrasonography,Obes Res 2003, 11:1488-1494.
[17] Weber R, Buckley M, Fried S, Kral J, Subcutaneous lipectomy causes a metabolic syndrome in hamsters, Am J Physiol Regul Integr Comp Physiol, 2000, 279:R936-43.
[18] Desprès J-P, Prud-Homme D, Pouliot MC, Tremblay A, Bouchard C, Estimation of deep abdominal adipose tissue accumulation from simple anthropometric measurements in men, Am J Clin Nutr, 1991, 54:471- 477.
[19] Kissebah AH, Central obesity: measurement and metabolic effects, Diabetes Rev,1997, 5:8-2.
[20] Kvist H, Chowdhury B, Grangard U, Tylén U, Sjöström L, Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations, Am J Clin Nutr, 1988, 48:1351-1361.
[21] Despres J-P, Lamarche B, Low-intensity endurance training, plasma lipoproteinas and the risk of coronary heart disease, J Intern Med, 1994, 236:7-22.
[22] Oshida T, Yamanouchi K, Hayamizu S, Sato Y, Long-term mild jogging increases insulin action despite no influence on body mass index or VO2 max, J Appl Physiol, 1989, 66:2206-2210.
[23] Abe T, Sakurai T, Kurata J, Kawakami Y, Fukunaga T, Subcutaneous and visceral fat distribution and daily physical activity: comparison between young and middle aged women, Br J Sports Med, 1996, 30:297-300.
[24] Grundy SM, Brewer HB JR, Cleeman JI, Smith SC JR, Lenfant C, Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Arterioscler Thromb Vasc Biol, 2004, 24: e13-e18.
[25] Friedwald WT, Levy RI, Fredrickson DS, Estimation of the concentration of the low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge, Clin Chem,1972, 18:499- 502.
[26] World Health Organisation, The challenge of obesity in the WHO European Region. Copenhagen, Bucharest 12 September 2005.
[27] Stolk RP, Wink O, Zelissen PM, Meijer R, Van Gils AP, Grobbee DE. Validity and reproducibility of ultrasonography for the measurement of intra-abdominal adipose tissue. Int J Obes Relat Metab Disord, 2001, 25:1346-1351