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Isolation of β-Sitosterol Diarabinoside from Rhizomes of Alpinia Galanga
Authors: N. K. Fuloria, S. Fuloria
Abstract:
Alpinia galanga is rhizome, generally known as Greater galangal and is selected for isolation of newer constituents accountable for various therapeutic activities. Present study is intended to isolate glycoside from Alpinia galanga rhizomes. Alpinia galanga methanolic extract was column chromatograph and eluted with ethyl acetate-methanol (99:1) to isolate compound β-Sitosterol Diarabinoside. Herein, the isolation and structural elucidation of new compound is described. Chemical investigation of methanolic extract of rhizomes of Alpinia galanga furnished a new compound β- Sitosterol Diarabinoside. The IR, NMR and MASS investigations of isolated compound confirmed its structure as β-Sitosterol Diarabinoside, which is isolated for the first time from a medicinal plant or any synthetic source.Keywords: Alpinia galanga, methanolic extract, β-Sitosterol Diarabinoside.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1334822
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[1] K. R. Kirtikar and B. D. Basu, Indian Medicinal Plants. Dehradoon, India: International Book Distributor, 1996.
[2] K. M. Nadkarni, The Indian Materia Medica. Bombay, India: Popular Prakashan, 2009.
[3] L. V. Asolkar, K. K. Kakkar and O. J. Chakre, Second Supplement To Glossary of Indian Medicinal Plants With Active Principles. New Delhi, India: National Institute of Science Communication and Information Research - CSIR publication, Part - I (A-K), 1992.
[4] B. Vanwyk and M. Wink, Medicinal Plant of The World. USA: Timber press, 2004.
[5] Research Guidelines for Evaluating the Safety and Efficacy of Herbal Medicines. Manila, Philippines: World Health Organization, Regional office for the Western Pacific, 1993.
[6] Y. R. Chadha, The Wealth of India (Raw materials). New Delhi, India: Council of Scientific and Industrial Research, Vol I. revised edition 2003.
[7] R. P. Rastogi and B. N. Mehrotra, Compendium of Indian Medicinal plants, New Delhi, India: National Institute of Science Communication and Information Research, CSIR 1970-1979, Vol. 2 (reprint 2006).
[8] A. M. Janssen and J. C. Scheffer, "Acetoxychavicol acetate an antifungal component of Alpinia galanga," Planta Medica, Vol.6, 507- 511, 1985.
[9] O. Jirawan and S. Tomoko, "Antimicrobial properties and action of galanga (Alpinia galanga Linn.) on Staphylococcus aureus," LWT-Food and Science Technology, Vol. 39, pp. 1214-1220, 2006.
[10] D. Bendjeddou, K. Lalaoui, D. Satta, "Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis," J. Ethnopharmacol., Vol. 88, pp. 155-160, 2003.
[11] H. Matsuda and Morikawa, "Gastro protective effects of phenyl propanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action," Eur. J. Pharmacol., 471, pp. 59-67, 2005.
[12] Ying Ye. BaoAn "Li.19S-19-Acetoxychavicol acetate isolated from Alpinia galanga inhibits human immune deficiency virus type 1 replication by blocking Rev Transport," J. Gen. Virol., 87(7), pp. 2047- 2053, 2006.
[13] S. Jaju, N. Indurwade, D. Sakarkar, N. Fuloria, M. Ali, "Isolation of galangogalloside from rhizomes of Alpinia galangal," Int. J. Green Pharm., 3 (2), pp. 144-147, 2009.
[14] S. B. Jaju, N. J. Indurwade, D. M. Sakarkar, N. K. Fuloria, M. Ali. "Galangoflavonoid Isolated from Rhizome of Alpinia galanga (L) Sw (Zingiberaceae)," Trop. J. Pharm. Res. 2009; 8 (6):545-550.
[15] S. B. Jaju, N. J. Indurwade, D. M. Sakarkar, N. K. Fuloria, M. Ali., Isolation of β-Sitosterodiglucoside and β-Sitsoteryl Arabinoside from Rhizomes Alpinia galanga. Asian J. Chem., 21 (3), pp. 2350-2356, 2009.
[16] S. B. Jaju, N. J. Indurwade, D. M. Sakarkar, N. K. Fuloria, M. Ali. Isolation of β-sitosterol diglucosyl caprate from Alpinia galanga. Pharmacog. Res., 2(4), pp. 264-266, 2010.