Synthesis and Characterization of Silver/Polylactide Nanocomposites
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Synthesis and Characterization of Silver/Polylactide Nanocomposites

Authors: Kamyar Shameli, Mansor Bin Ahmad, Wan Md Zin Wan Yunus, Nor Azowa Ibrahim, Maryam Jokar, Majid Darroudi


Silver/polylactide nanocomposites (Ag/PLA-NCs) were synthesized via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were used as a silver precursor and reducing agent in the polylactide (PLA). The properties of Ag/PLA-NCs were studied as a function of the weight percentages of silver nanoparticles (8, 16 and 32 wt% of Ag-NPs) relative to the weight of PLA. The Ag/PLA-NCs were characterized by Xray diffraction (XRD), transmission electron microscopy (TEM), electro-optical microscopy (EOM), UV-visible spectroscopy (UV-vis) and Fourier transform infrared spectroscopy (FT-IR). XRD patterns confirmed that Ag-NPs crystallographic planes were face centered cubic (fcc) type. TEM images showed that mean diameters of Ag-NPs were 3.30, 3.80 and 4.80 nm. Electro-optical microscopy revealed excellent dispersion and interaction between Ag-NPs and PLA films. The generation of silver nanoparticles was confirmed from the UVvisible spectra. FT-IR spectra showed that there were no significant differences between PLA and Ag/PLA-NCs films. The synthesized Ag/PLA-NCs were stable in organic solution over a long period of time without sign of precipitation.

Keywords: Nanocomposites, Polylactide, Silver Nanoparticles, Sodium Borohydride, Transmission Electron Microscopy.

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[1] Y. Chen, A. F. T. Mak, M. Wang, J. Li, M. S. Wong, PLLA scaffolds with biomimetic apatite coating and biomimetic apatite/collagen composite coating to enhance osteoblastlike cells attachment and activity, Surface and Coatings Technology, 201, 575-580, 2006.
[2] K. Tomihata, Y. Ikada, In vitro and in vivo degradation of films of chitin and its deacetylated derivatives, Biomaterials, 18, 567-575, 1997.
[3] D. H. Reneker, I. Chun, Nanometre diameter fibres of polymer, produced by electrospinning, Nanotechnology, 7, 216-223, 1996.
[4] V. J. Chen, P. X. Ma, The effect of surface area on the degradation rate of nano-fibrous poly (L-lactic acid) foams, Biomaterials, 27, 3708-3715, 2006.
[5] W. J. Li, R. Tuli, X. Huang, P. Laquerriere , R. S. Tuan, Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold, Biomaterials, 26, 5158-5166, 2005.
[6] X. Chen , H. J. Schluesener, Nanosilver: a nanoproduct in medical application, Toxicology Letters, 176, 1-12, 2008.
[7] F. Furno, K. S. Morley, B. Wong, Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection, Journal of Antimicrobial Chemotherapy, 54, 1019-1024, 2004.
[8] D. K. Riley, D.C. Classen, L. E. Stevens, J. P. Burke, A large randomized clinical trial of a silver-impregnated urinary catheter: lack of efficacy and staphylococcal superinfection, The American Journal of Medicine, 98, 349-356, 1995.
[9] J. H. Crabtree, R. J. Burchette, R. A. Siddiqi, I. T. Huen, L. L. Hadnott, D. A. Fishman, The efficacy of silver-ion implanted catheters in reducing peritoneal dialysis-related infections, Peritoneal Dialysis International, 23, 368-374, 2003.
[10] B. Shan, Y. Z. Cai, J. D. Brooks, H. Corke, Antibacterial properties of Polygonum cuspidatum roots and their major bioactive constituents, Food Chemistry, 109, 530-537, 2008.
[11] V. Alt, T. Bechert, P. Steinrucke, An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement, Biomaterials, 25, 4383-4391, 2004.
[12] M. Rong, M. Zhang, H. Liu, H. Zheng, Synthesis of silver nanoparticles and their self organization behavior in epoxy resin, Polymer, 40, 6169- 6178, 1999.
[13] M. Zheng, M. Gu, Y. Jin , G. Jin, Optical properties of silver dispersed PVP thin film, Materials Research Bulletin, 36, 853-859, 2001.
[14] P. K. Khanna, N. Singh, S. Charan, V. V. V. S. Subbarao, R. Gokhale, U. P. Mulik, Synthesis and characterization of Ag/PVA nanocomposites by chemical reduction method Materials Chemistry and Physics, 93, 117- 121, 2005.
[15] H. W. Lu, S. H. Liu, X. L. Wang, X. F. Qian, J.Yin, Z. K. Zhu, Silver nanocrystals by hyperbranched polyurethane-assisted photochemical reduction of Ag+, Materials Chemistry and Physics, 81, 104-107, 2003.
[16] Z. Zhang, L. Zhang, S. Wang, W. Chen, Y. Lei, A convenient route to polyacrylonitrile/silver nanoparticle composite by simultaneous polymerization-reduction approach Polymer, 42, 8315-8318, 2001.
[17] R. A. Jain, The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide) (PLGA) devices, Biomaterials, 2, 2475-2490, 2000.
[18] A. Mikos, M. Lyman, L. Freed, R. Langer, Wetting of poly (L-lactic acid) and poly (D, L-lactic-co-glycolic acid) foams for tissue culture, Biomaterials, 15, 55-58, 1994.
[19] M. S. Taylor, A. U. Daniels, K. P. Andriano, J. Six. Heller, Bioabsorbable polymers: In vitro acute toxicity of accumulated degradation products, Journal of Applied Biomaterials, 5, 151-157, 1994.
[20] T. Park, S. Cohen, R. Langer, Poly (L-lactic acid)/pluronic blends: Characterization of phase separation behavior, degradation, morphology and as protein releasing matrices, macromolecules, 25, 116-122, 1992.
[21] J. Turkevich, P. C. Stevenson, J. Hillier, The nucleation and growth processes in the synthesis of colloidal gold, Discussions of the Faraday Society, 11, 55-75, 1951.
[22] A. Roucoux, J. Schulz, H. Patin, Reduced transition metal colloids: a novel family of reusable catalysts, Chemical Reviews, 102, 3757-3778, 2002.
[23] M. K. Temgire, S. S. Joshi, Optical and structural studies of silver nanoparticles, Radiation Physics and Chemistry, 71, 1039-1044, 2004.
[24] V. Prasad, C. D. Souza, D. Yadav, A. J. Shaikh, N. Vigneshwaran, Spectroscopic characterization of zinc oxide nanorods synthesized by solidstate reaction, Spectrochimica Acta Part A. Molecular and Bimolecular Spectroscopy, 65, 173-178, 2006.
[25] N. Aihara, K. Torigoe, K. Esumi, Preparation and characterization of gold and silver nanoparticles in layered laponite suspensions, Langmuir, 14, 4945-4949, 1998.
[26] X. Z. Lin, X. Teng, H. Yang, Direct synthesis of narrowly dispersed silver nanoparticles using a single-source precursor, Langmuir, 19, 10081-10085, 2003.
[27] J. Lerme, B. Palpant, B. Pevel, M. Pellarin, M. Treilleux, J. L. Vialle, A. Perez, M. Broger, Quenching of the size effects in free and matrixembedded silver clusters, Physical Review Letters, 80, 5105-5108, 1998.
[28] H. Younes, D. Cohn, Phase separation in poly (ethylene glycol)/poly (lactic acid) blends, European Polymer Journal, 24, 765-773, 1988.
[29] M. Agarwal, K. W. Koelling, J. J. Chalmers, Characterization of the degradation of poly- lactic acid in a well-controlled composting system Biotechnology Progress, 14, 517-526, 1998.
[30] E. C. Da silva, M. G. A. Da silva, S. M. P. Meneghetti, G. Machado, M. A. R. C. Alencar, J. M. Hickmann, M. R. Meneghetti, Synthesis of colloids based on gold nanoparticles dispersed in castor oil, Journal of nanoparticle research, 10, 201-208, 2008.