Whole Body CT for a Patient with Sepsis

Authors: Y. Yanagawa, K. Aihara, S. Watanabe, M. Takemoto, T. Naito, T. Iba, H. Tanaka

Abstract:

This study retrospectively investigated the significance of whole body CT (WCT) for patients with sepsis. A medical chart review was retrospectively performed for all patients with systemic inflammatory response syndrome that were treated initially between April 2011 and March 2012. The subjects were divided into a WCT group that underwent WCT on arrival and a control group. Results of this study suggested that WCT for sepsis was useful for elderly patients whose chief complaint or physiological findings could not suggest the anatomical site of infection, to determine the infectious focus and indications/method for surgery, to diagnose the basic diseases associated with opportunistic infections and to evaluate complicated diseases

Keywords: Sepsis, CT, outcome.

Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1074946

References:

[1] R.P.Dellinger , M.M.Levy, J.M.Carlet, et al, “Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock,” Crit Care Med vol.36, pp296-327, 2008.
[2] C.P. Bleekr-Rovers, F.J.Vos, E.M.Kleijn, et al, “A prospective multicenter study on fever of unknown origin: the yield of a structured diagnostic protocol,” Medicine (Baltimore), vol.86,pp26-38, 2007.
[3] J.Barkhausen, F.Stöblen, E.Dominguez-Fernandez, et al, “Impact of CT in patients with sepsis of unknown origin,” Acta Radiol vol.40, pp552-5, 1999.
[4] G. Kumar, N. Kumar, A Taneja, et al, “from the Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators. Nationwide trends of severe sepsis in the 21st century (2000-2007),” Chest vol.140, pp1223-31, 2011.
[5] S.Huber-Wagner, R.Lefering, L.M.Qvick, et al; Working Group on Polytrauma of the German Trauma Society, “Effect of whole-body CT during trauma resuscitation on survival: a retrospective, multicentre study,” Lancet, vol 373, pp1455-61,2009.
[6] T.Nagai, C.Inoue, K.Tonouchi, et al,”Multiple Organ Failure Followed by Intrauterine Klebsiella Pneumoiiiae Infection Associated with Diabetes Mellitus,” Kitakanto Med J vol.59, pp151-5, 2009. In Japanese
[7] Y.Eriguchi, S.Ri, N.Fujimura,et al, “A case of invasive Group A Streptococca1 infection,” Rinsho to Kenkyu vol.89, pp111-3, 2012. In Japanese
[8] T.Fujiwara, T.Nagai, K.Kaneko, et al, “Candida Glabrata Fungemia After Amputation of an Infected Diabetic Foot,” Kitakanto Med J vol.60, pp259-63, 2010. In Japanese
[9] Y.Yanagawa, Y.Hirano, N.Matsumoto, et al, “Emphysematous pyelonephritis induced by Citrobacter freundii,” J Emerg Trauma Shock in press.
[10] M.Gotthardt, C.P.Bleeker-Rovers, O.C.Boerman, et al, “Imaging of inflammation by PET, conventional scintigraphy, and other imaging techniques,” J Nucl Med vol.51, pp1937-49, 2010.
[11] S.M.Opal, T.D.Girard, E.W.Ely, , “The immunopathogenesis of sepsis in elderly patients,” Clin Infect Dis. Vol.41 Suppl 7, ppS504-12, 2005.
[12] D.J.Brenner, E.J.Hall, “Computed tomography: An increasing source of radiation exposure,” N Engl J Med vol. 357, pp2277-84, 2007.