Geometrical Based Unequal Droplet Splitting Using Microfluidic Y-Junction
Commenced in January 2007
Frequency: Monthly
Edition: International
Paper Count: 32795
Geometrical Based Unequal Droplet Splitting Using Microfluidic Y-Junction

Authors: Bahram Talebjedi, Amirmohammad Sattari, Ahmed Zoher Sihorwala, Mina Hoorfar


Among different droplet manipulations, controlled droplet-splitting is of great significance due to its ability to increase throughput and operational capability. Furthermore, unequal droplet-splitting can provide greater flexibility and a wider range of dilution factors. In this study, we developed two-dimensional, time-dependent complex fluid dynamics simulations to model droplet formation in a flow focusing device, followed by splitting in a Y-shaped junction with sub-channels of unequal widths. From the results obtained from the numerical study, we correlated the diameters of the droplets in the sub-channels to the Weber number, thereby demarcating the droplet splitting and non-splitting regimes.

Keywords: Microfluidics, unequal droplet splitting, two phase flow, flow focusing device.

Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 677


[1] B. Talebjedi, N. Tasnim, M. Hoorfar, G. F. Mastromonaco, and M. De Almeida Monteiro Melo Ferraz, “Exploiting Microfluidics for Extracellular Vesicle Isolation and Characterization: Potential Use for Standardized Embryo Quality Assessment,” Front. Vet. Sci., vol. 7, p. 1139, 2021.
[2] B. Talebjedi, M. Ghazi, N. Tasnim, S. Janfaza, and M. Hoorfar, “Chemical Engineering and Processing - Process Intensification Performance optimization of a novel passive T-shaped micromixer with deformable baffles,” Chem. Eng. Process. - Process Intensif., vol. 163, no. March, p. 108369, 2021.
[3] R. De Ruiter, A. M. Pit, V. M. De Oliveira, M. H. G. Duits, D. Van Den Ende, and F. Mugele, “Electrostatic potential wells for on-demand drop manipulation in microchannels,” Lab Chip, vol. 14, no. 5, pp. 883–891, Mar. 2014.
[4] J. H. Choi, S. K. Lee, J. M. Lim, S. M. Yang, and G. R. Yi, “Designed pneumatic valve actuators for controlled droplet breakup and generation,” Lab Chip, vol. 10, no. 4, pp. 456–461, 2010.
[5] J. H. Jung, G. Destgeer, B. Ha, J. Park, and H. J. Sung, “On-demand droplet splitting using surface acoustic waves,” Lab Chip, vol. 16, no. 17, pp. 3235–3243, Aug. 2016.
[6] M. Yamada, S. Doi, H. Maenaka, M. Yasuda, and M. Seki, “Hydrodynamic control of droplet division in bifurcating microchannel and its application to particle synthesis,” J. Colloid Interface Sci., vol. 321, no. 2, pp. 401–407, 2008.
[7] C. G. Yang, R. Y. Pan, and Z. R. Xu, “A single-cell encapsulation method based on a microfluidic multi-step droplet splitting system,” Chinese Chem. Lett., vol. 26, no. 12, pp. 1450–1454, 2015.