Commenced in January 2007
Paper Count: 30850
Fabrication of ZnO Nanorods Based Biosensor via Hydrothermal Method
Abstract:Biosensors are playing vital role in industrial, clinical, and chemical analysis applications. Among other techniques, ZnO based biosensor is an easy approach due to its exceptional chemical and electrical properties. ZnO nanorods have positively charged isoelectric point which helps immobilize the negative charge glucose oxides (GOx). Here, we report ZnO nanorods based biosensors for the immobilization of GOx. The ZnO nanorods were grown by hydrothermal method on indium tin oxide substrate (ITO). The fabrication of biosensors was carried through batch processing using conventional photolithography. The buffer solutions of GOx were prepared in phosphate with a pH value of around 7.3. The biosensors effectively immobilized the GOx and result was analyzed by calculation of voltage and current on nanostructures.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1474976Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 482
 N. A. Rakow and K. S. Suslick, “A colorimetric sensor array for odour visualization”. Nature, vol.406, pp. 710-713, August 2000.
 Y. Yang, H. Yang, M. Yang, G. Shen, and R. Yu, “Amperometric glucose biosensor based on a surface treated nanoporous ZrO 2 /chitosan composite film as immobilization matrix”. Analytica Chimica Acta, vol. 525, pp. 213-220.November 2004.
 C. X. Xu, X. W. Sun, Z. L. Dong, S. T. Tan, Y. P. Cui and B.P. Wang, “Manganese-doped zinc oxide tetratubes and their photoluminescent properties”. Journal of applied physics, vol. 98(11), pp. 113513(1-5), December 2005.
 J. Chen, W. Lei, W. Chai, Z. Zhang, C. Li and X. Zhang, “High field emission enhancement of ZnO-nanorods via hydrothermal synthesis" Solid-State Electronics, vol. 52, pp. 294-298, February 2008.
 Y. W. Heo, S. J. Pearton, “ZnO Thin-Film and Nanowire-Based Sensor Applications”, In Semiconductor Device-Based Sensors for Gas, Chemical, and Biomedical Applications, vol.149, pp. 156-221, April 2016. CRC Press.
 B. Wu, G. Zhang, S. Shuang, and M. M. Choi, “Biosensors for determination of glucose with glucose oxidase immobilized on an eggshell membrane”, Talanta, vol. 64, p.p. 546-553, October 2004.
 S. Ahammad and A. J. “Hydrogen peroxide biosensors based on horseradish peroxidase and hemoglobin”, J Biosens Bioelectron, vol. S9, pp. 1-11, January 2013.
 T. Kong, Y. Chen, Y. Ye, K. Zhang, Z. Wang, and X. Wang, “An amperometric glucose biosensor based on the immobilization of glucose oxidase on the ZnO nanotubes”, Sensors and Actuators B: Chemical, vol. 138, p.p. 344-350, April 2009.
 X. Lu, H. Zhang, Y. Ni, Q. Zhang and J. Chen, “Porous nanosheet-based ZnO microspheres for the construction of direct electrochemical biosensors. Biosensors and bioelectronics, vol. 24, p.p. 93-98, September 2008.
 Z. W. Zhao, X. J. Chen, B. K. Tay, J. S. Chen, Z. J. Han, and K. A. Khor, “A novel amperometric biosensor based on ZnO: Co nanoclusters for biosensing glucose”, Biosensors and Bioelectronics, vol. 23, p.p. 135-139, August 2007.
 P. Bianco, J. Haladjian, C.Bourdillon, “Immobilization of glucose oxidase on carbon electrodes”, Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, vol.293, p.p 151-163, October 1990.
 B. Najma, A. K. Kasi, J. K. Kasi, A. Akbar, S. M. A. Bokhari. and I. R. Stroe, “ZnO/AAO photocatalytic membranes for efficient water disinfection: Synthesis, characterization and antibacterial assay”, Applied Surface Science, vol. 448, pp.104-114, August 2018.
 R. Tenne, Inorganic nanotubes and fullerene-like nanoparticles. Journal of materials research. vol. 21, pp. 2726-43, Nov 2006.
 AE. Nel, L. Mädler, D. Velegol, T. Xia, EM. Hoek, P. Somasundaran, F. Klaessig, V. Castranova, M. Thompson. “Understanding biophysicochemical interactions at the nano–bio interface”. Nature materials, vol. 8, pp. 543, Jul 2009.
 T. Kong, Y. Chen, Y. Ye, K. Zhang, Z. Wang, X. Wang, “An amperometric glucose biosensor based on the immobilization of glucose oxidase on the ZnO nanotubes”, Sensors and Actuators B: Chemical. Vol. 138, pp.344-350, April 2009.
 A. Salimi, E. Sharifi, A. Noorbakhsh, S. Soltanian, “Immobilization of glucose oxidase on electrodeposited nickel oxide nanoparticles: direct electron transfer and electrocatalytic activity”, Biosensors and Bioelectronics, vol. 22, pp. 3146-3153, June 2007.
 O. Y. Nadzhafova, V. N. Zaitsev, M. V. Drozdova, A. Vaze, J. F. Rusling, “Heme proteins sequestered in silica sol–gels using surfactants feature direct electron transfer and peroxidase activity”, Electrochemistry communications, vol. 6, pp. 205-209, Feb 2004.
 T. Kong, Y. Chen Y. Ye, K. Zhang, Z. Wang, X. Wang, “An amperometric glucose biosensor based on the immobilization of glucose oxidase on the ZnO nanotubes”, Sensors and Actuators B: Chemical. Vol. 138, pp.344-350, April 2009.
 M. Ahmad, C. Pan, Z. Luo, J. Zhu, “A single ZnO nanofiber-based highly sensitive amperometric glucose biosensor”, The Journal of Physical Chemistry C, vol. 114, pp. 9308-9313, May 2010.
 X. Lu, H. Zhang, Y. Ni,Q. Zhang, J. Chen, “Porous nanosheet-based ZnO microspheres for the construction of direct electrochemical biosensors”, Biosensors and bioelectronics, vol.24, pp.93-98, Sep 2008.
 J. Wang, S. Li, Y. Zhang, “A sensitive DNA biosensor fabricated from gold nanoparticles, carbon nanotubes, and zinc oxide nanowires on a glassy carbon electrode”, Electrochimica Acta, vol.55, pp. 4436- 4440, Jun 2010.
 L. Lu, L. Zhang, X. Zhang, Z. Wu, S. Huan, G. Shen, R. A. Yu, “A MgO Nanoparticles Composite Matrix‐Based Electrochemical Biosensor for Hydrogen Peroxide with High Sensitivity. Electroanalysis”, An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, vol.22, pp. 471-477, Feb 2010.
 A. Wei, X. W. Sun, J. X. Wang, Y. Lei, X. P. Cai, C. M. Li, Z. L. Dong, W. Huang, “Enzymatic glucose biosensor based on ZnO nanorod array grown by hydrothermal decomposition”, Applied Physics Letters, vol.89, pp. 123902, Sep 2006.
 Z. Yan, X. Y. Zhou, G. K. Pang, T. Zhang, W. L. Liu, J. G. Cheng, Z. T Song, S. L. Feng, L. H. Lai, J. Z. Chen, Y. Wang, “ZnO-based film bulk acoustic resonator for high sensitivity biosensor applications”, Applied physics letters, vol.90, pp. 143503, Apr 2007.
 X. Lu, H. Zhang, Y. Ni, Q. Zhang, J. Chen, “ Porous nanosheet-based ZnO microspheres for the construction of direct electrochemical biosensors”, Biosensors and bioelectronics, vol.24, pp. 93-98, Sep 2008.
 J.K. Kasi, A.K. Kasi, M. Bokhari, and N. Afzulpurkar, “Fabrication of Zinc Oxidenanorods Based Gas Sensor”, World applied Science Journal, vol.30, pp.198-204, March 2014.