Commenced in January 2007
Paper Count: 32229
Nanomaterial Based Electrochemical Sensors for Endocrine Disrupting Compounds
Authors: Gaurav Bhanjana, Ganga Ram Chaudhary, Sandeep Kumar, Neeraj Dilbaghi
Abstract:Main sources of endocrine disrupting compounds in the ecosystem are hormones, pesticides, phthalates, flame retardants, dioxins, personal-care products, coplanar polychlorinated biphenyls (PCBs), bisphenol A, and parabens. These endocrine disrupting compounds are responsible for learning disabilities, brain development problems, deformations of the body, cancer, reproductive abnormalities in females and decreased sperm count in human males. Although discharge of these chemical compounds into the environment cannot be stopped, yet their amount can be retarded through proper evaluation and detection techniques. The available techniques for determination of these endocrine disrupting compounds mainly include high performance liquid chromatography (HPLC), mass spectroscopy (MS) and gas chromatography-mass spectrometry (GC–MS). These techniques are accurate and reliable but have certain limitations like need of skilled personnel, time consuming, interference and requirement of pretreatment steps. Moreover, these techniques are laboratory bound and sample is required in large amount for analysis. In view of above facts, new methods for detection of endocrine disrupting compounds should be devised that promise high specificity, ultra sensitivity, cost effective, efficient and easy-to-operate procedure. Nowadays, electrochemical sensors/biosensors modified with nanomaterials are gaining high attention among researchers. Bioelement present in this system makes the developed sensors selective towards analyte of interest. Nanomaterials provide large surface area, high electron communication feature, enhanced catalytic activity and possibilities of chemical modifications. In most of the cases, nanomaterials also serve as an electron mediator or electrocatalyst for some analytes.
Keywords: Sensors, endocrine disruptors, nanoparticles, electrochemical, microscopy.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1132725Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 817
 Y. Tarumi, M. P. Wilson, O. Szafran, & G. R. Spooner, (2013). Randomized, double-blind, placebo-controlled trial of oral docusate in the management of constipation in hospice patients. Journal of pain and symptom management, 45(1), 2-13.
 P. Paré, & R. N. Fedorak, (2014). Systematic review of stimulant and nonstimulant laxatives for the treatment of functional constipation. Canadian Journal of Gastroenterology and Hepatology, 28(10), 549-557.
 V. Hurdon, R. Viola, & C. Schroder, (2000). How useful is docusate in patients at risk for constipation? A systematic review of the evidence in the chronically ill. Journal of pain and symptom management, 19(2), 130-136.
 G. Bhanjana, N. Dilbaghi, V. Bhalla, K. H. Kim, & S. Kumar, (2017). Direct ultrasensitive redox sensing of mercury using a nanogold platform. Journal of Molecular Liquids, 225, 598-605.
 G. Bhanjana, N. Dilbaghi, N. K. Singhal, K. H. Kim, & S. Kumar, (2017). Zinc oxide nanopillars as an electrocatalyst for direct redox sensing of cadmium. Journal of Industrial and Engineering Chemistry.
 S. Verma, G. Bhanjana, N. Dilbaghi, S Kumar, & A. Umar, (2014). Urea Biosensor Based on Zinc Oxide/Multi-Walled Carbon Nanotubes/Chitosan Nanocomposite Thin Films. Sensor Letters, 12(1), 50-55.
 V. Sosa, C. Barceló, N. Serrano, C. Ariño, J. M. Díaz-Cruz, & M. Esteban, (2015). Antimony film screen-printed carbon electrode for stripping analysis of Cd (II), Pb (II), and Cu (II) in natural samples. Analytica chimica acta, 855, 34-40.
 R. Rosal, I. Rodea-Palomares, K. Boltes, F. Fernández-Piñas, F. Leganés, & A. Petre, (2010). Ecotoxicological assessment of surfactants in the aquatic environment: combined toxicity of docusate sodium with chlorinated pollutants. Chemosphere, 81(2), 288-293.
 G. Bhanjana, N. Dilbaghi, K. H. Kim, & S. Kumar, (2017). Low temperature synthesis of copper oxide nanoflowers for lead removal using sonochemical route. Journal of Molecular Liquids, 244, 506-511.
 K. Phiwdang, S. Suphankij, W. Mekprasart, & W. Pecharapa, (2013). Synthesis of CuO nanoparticles by precipitation method using different precursors. Energy Procedia, 34, 740-745.
 R. Etefagh, E. Azhir, & N. Shahtahmasebi, (2013). Synthesis of CuO nanoparticles and fabrication of nanostructural layer biosensors for detecting Aspergillus niger fungi. Scientia Iranica, 20(3), 1055-1058.